WO2010042887A3 - Methods for preparing oxazolidinones and compositions containing them - Google Patents
Methods for preparing oxazolidinones and compositions containing them Download PDFInfo
- Publication number
- WO2010042887A3 WO2010042887A3 PCT/US2009/060267 US2009060267W WO2010042887A3 WO 2010042887 A3 WO2010042887 A3 WO 2010042887A3 US 2009060267 W US2009060267 W US 2009060267W WO 2010042887 A3 WO2010042887 A3 WO 2010042887A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- compositions containing
- preparing
- oxazolidinones
- preparing oxazolidinones
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
- C07F5/02—Boron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
Abstract
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020117010217A KR101674146B1 (en) | 2008-10-10 | 2009-10-09 | Methods for preparing oxazolidinones and compositions containing them |
JP2011531233A JP5773875B2 (en) | 2008-10-10 | 2009-10-09 | Methods of preparing oxazolidinones and compositions containing them |
CN200980140144.4A CN102177156B (en) | 2008-10-10 | 2009-10-09 | Prepare the method for (oxazolidinon-5-yl-methyl)-2-thiophene-carboxamides and the composition containing (oxazolidinon-5-yl-methyl)-2-thiophene-carboxamides |
EP09749235.9A EP2346858B1 (en) | 2008-10-10 | 2009-10-09 | Methods for preparing oxazolidinones and compositions containing them |
CA2738671A CA2738671C (en) | 2008-10-10 | 2009-10-09 | Methods for preparing oxazolidinones and compositions containing them |
ES09749235T ES2748505T3 (en) | 2008-10-10 | 2009-10-09 | Methods for the preparation of oxazolidinones and compositions containing them |
MX2011003820A MX2011003820A (en) | 2008-10-10 | 2009-10-09 | Methods for preparing oxazolidinones and compositions containing them. |
EP14159112.3A EP2757104B1 (en) | 2008-10-10 | 2009-10-09 | Compounds used in the synthesis of oxazolidinones |
AU2009303301A AU2009303301B2 (en) | 2008-10-10 | 2009-10-09 | Methods for preparing oxazolidinones and compositions containing them |
RU2011115109/04A RU2556234C2 (en) | 2008-10-10 | 2009-10-09 | Methods of producing oxazolidinones and compositions containing same |
MX2014004600A MX366793B (en) | 2008-10-10 | 2009-10-09 | Methods for preparing oxazolidinones and compositions containing them. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10446908P | 2008-10-10 | 2008-10-10 | |
US61/104,469 | 2008-10-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2010042887A2 WO2010042887A2 (en) | 2010-04-15 |
WO2010042887A3 true WO2010042887A3 (en) | 2010-06-24 |
Family
ID=41382395
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2009/060267 WO2010042887A2 (en) | 2008-10-10 | 2009-10-09 | Methods for preparing oxazolidinones and compositions containing them |
Country Status (13)
Country | Link |
---|---|
US (2) | US8604209B2 (en) |
EP (2) | EP2346858B1 (en) |
JP (1) | JP5773875B2 (en) |
KR (1) | KR101674146B1 (en) |
CN (2) | CN106220621B (en) |
AU (1) | AU2009303301B2 (en) |
CA (1) | CA2738671C (en) |
ES (2) | ES2748505T3 (en) |
HK (2) | HK1200169A1 (en) |
MX (2) | MX366793B (en) |
RU (2) | RU2556234C2 (en) |
SG (2) | SG195544A1 (en) |
WO (1) | WO2010042887A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2659792C1 (en) * | 2008-10-10 | 2018-07-04 | Мерк Шарп Энд Домэ Корп. | Oxazolidinones and the method of their cleaning |
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KR100854211B1 (en) * | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | Novel oxazolidinone derivatives, a process for the preparation thereof and pharmaceutical composition comprising the same for antibiotics |
KR101739923B1 (en) | 2009-02-03 | 2017-05-25 | 머크 샤프 앤드 돔 코포레이션 | Crystalline form of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
US8580767B2 (en) * | 2009-05-28 | 2013-11-12 | Trius Therapeutics, Inc. | Oxazolidinone containing dimer compounds, compositions and methods to make and use |
US20120065170A1 (en) | 2010-09-10 | 2012-03-15 | Micurx Pharmaceuticals, Inc. | Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections |
WO2016009401A2 (en) * | 2014-07-18 | 2016-01-21 | Dr. Reddy's Laboratories Limited | Preparation of tedizolid phosphate |
CN105367547B (en) * | 2014-08-19 | 2019-04-23 | 北京桦冠生物技术有限公司 | A kind of new synthesis process of oxazoline ketone antibiotic |
WO2016041505A1 (en) * | 2014-09-17 | 2016-03-24 | 正大天晴药业集团股份有限公司 | Tedizolid phosphate, intermediate and preparation method thereof |
CN104496979A (en) * | 2014-09-17 | 2015-04-08 | 博瑞生物医药技术(苏州)有限公司 | Method for preparing oxazolidinone compound and intermediate thereof |
CN104327119A (en) * | 2014-10-17 | 2015-02-04 | 苏州明锐医药科技有限公司 | Preparation method of tedizolid phosphate |
WO2016088101A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
WO2016088102A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
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WO2016088100A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
CN104558034A (en) * | 2015-01-21 | 2015-04-29 | 齐鲁制药有限公司 | Novel crystal form of tedizolid phosphate disodium salt and preparation method of novel crystal form |
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CN104892592A (en) * | 2015-03-30 | 2015-09-09 | 成都惟新医药科技有限公司 | Preparation method for tedizolid |
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KR101674146B1 (en) | 2016-11-08 |
US9328087B2 (en) | 2016-05-03 |
SG10201702946RA (en) | 2017-05-30 |
HK1232221A1 (en) | 2018-01-05 |
AU2009303301B2 (en) | 2014-09-11 |
CN102177156A (en) | 2011-09-07 |
CA2738671C (en) | 2018-05-01 |
EP2757104A1 (en) | 2014-07-23 |
SG195544A1 (en) | 2013-12-30 |
EP2346858B1 (en) | 2019-08-07 |
RU2556234C2 (en) | 2015-07-10 |
ES2748505T3 (en) | 2020-03-17 |
HK1200169A1 (en) | 2015-07-31 |
US20140206878A1 (en) | 2014-07-24 |
CN106220621A (en) | 2016-12-14 |
RU2659792C1 (en) | 2018-07-04 |
ES2744907T3 (en) | 2020-02-26 |
US8604209B2 (en) | 2013-12-10 |
CN102177156B (en) | 2016-08-24 |
CN106220621B (en) | 2019-06-11 |
EP2757104B1 (en) | 2019-08-14 |
MX2011003820A (en) | 2011-06-16 |
JP2012505252A (en) | 2012-03-01 |
RU2011115109A (en) | 2012-11-20 |
KR20110071107A (en) | 2011-06-28 |
AU2009303301A1 (en) | 2010-04-15 |
CA2738671A1 (en) | 2010-05-15 |
US20100093669A1 (en) | 2010-04-15 |
MX366793B (en) | 2019-07-24 |
JP5773875B2 (en) | 2015-09-02 |
EP2346858A2 (en) | 2011-07-27 |
WO2010042887A2 (en) | 2010-04-15 |
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