WO2008010070A3 - Novel oxazolidinone derivatives - Google Patents
Novel oxazolidinone derivatives Download PDFInfo
- Publication number
- WO2008010070A3 WO2008010070A3 PCT/IB2007/002019 IB2007002019W WO2008010070A3 WO 2008010070 A3 WO2008010070 A3 WO 2008010070A3 IB 2007002019 W IB2007002019 W IB 2007002019W WO 2008010070 A3 WO2008010070 A3 WO 2008010070A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- present
- pneumoniae
- derivatives
- oxazolidinone derivatives
- novel oxazolidinone
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
The present invention relates to novel compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof. The present invention more particularly provides novel Oxazolidinone derivatives of the general formula (I). The novel Oxazolidinone derivatives of the present invention may be useful as antibacterial agents, particularly for intravenous injections and are also useful in the treatment of conditions such as nosocomial pneumoniae, community acquired pneumoniae, Vancomycin resistant enterococci (VRE) caused by Methicillin resistant Staphylococcus Aureus (MRSA) and penicillin resistant Streptococcus Pneumoniae. The compounds of the present invention are effective against a number of human or animal pathogens, clinical isolates, including Vancomycin and Methicillin resistant organisms.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1253CH2006 | 2006-07-19 | ||
IN1253/CHE/2006 | 2006-07-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008010070A2 WO2008010070A2 (en) | 2008-01-24 |
WO2008010070A3 true WO2008010070A3 (en) | 2010-02-11 |
Family
ID=38957145
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2007/002019 WO2008010070A2 (en) | 2006-07-19 | 2007-07-18 | Novel oxazolidinone derivatives |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2008010070A2 (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993023384A1 (en) * | 1992-05-08 | 1993-11-25 | The Upjohn Company | Oxazolidinones containing a substituted diazine moiety and their use as antimicrobials |
JPH11322729A (en) * | 1998-03-09 | 1999-11-24 | Hokuriku Seiyaku Co Ltd | Dithiocarbamic acid derivative |
EP1130016A1 (en) * | 1998-11-11 | 2001-09-05 | Hokuriku Seiyaku Co., Ltd. | Thiocarbamic acid derivatives |
-
2007
- 2007-07-18 WO PCT/IB2007/002019 patent/WO2008010070A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993023384A1 (en) * | 1992-05-08 | 1993-11-25 | The Upjohn Company | Oxazolidinones containing a substituted diazine moiety and their use as antimicrobials |
JPH11322729A (en) * | 1998-03-09 | 1999-11-24 | Hokuriku Seiyaku Co Ltd | Dithiocarbamic acid derivative |
EP1130016A1 (en) * | 1998-11-11 | 2001-09-05 | Hokuriku Seiyaku Co., Ltd. | Thiocarbamic acid derivatives |
Non-Patent Citations (2)
Title |
---|
DATABASE CAPLUS [online] 20 March 2009 (2009-03-20), Database accession no. 2007:249549 * |
DATABASE CAPLUS [online] 20 March 2009 (2009-03-20), Database accession no. 2007:413000 * |
Also Published As
Publication number | Publication date |
---|---|
WO2008010070A2 (en) | 2008-01-24 |
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