WO2007133803A3 - Treatment of mycobacterial infections - Google Patents
Treatment of mycobacterial infections Download PDFInfo
- Publication number
- WO2007133803A3 WO2007133803A3 PCT/US2007/011722 US2007011722W WO2007133803A3 WO 2007133803 A3 WO2007133803 A3 WO 2007133803A3 US 2007011722 W US2007011722 W US 2007011722W WO 2007133803 A3 WO2007133803 A3 WO 2007133803A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- treatment
- mycobacterial infections
- mediated
- mycobacteria
- infections caused
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
Abstract
The present invention relates to methods for treating, reducing the risk of, and preventing mycobacterial infections, for example infections caused or mediated by Mycobacterium tuberculosis or nontuberculosis mycobacteria and in particular those infections caused or mediated by resistant or highly virulent strains of mycobacteria, using a safe and effective amount of an antibiotic compound.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80077806P | 2006-05-15 | 2006-05-15 | |
US60/800,778 | 2006-05-15 | ||
US89909507P | 2007-02-01 | 2007-02-01 | |
US60/899,095 | 2007-02-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007133803A2 WO2007133803A2 (en) | 2007-11-22 |
WO2007133803A3 true WO2007133803A3 (en) | 2008-01-10 |
Family
ID=38578556
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/011722 WO2007133803A2 (en) | 2006-05-15 | 2007-05-15 | Treatment of mycobacterial infections |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2007133803A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2776310A1 (en) * | 2009-10-13 | 2011-04-21 | Rib-X Pharmaceuticals, Inc. | Pharmaceutical compositions of radezolid and theur use in treting, preventing, or reducing the risk of microbial infections |
WO2011139832A2 (en) * | 2010-04-28 | 2011-11-10 | Rib-X Pharmaceuticals, Inc. | Method for treating mycobacterial infections |
WO2016061772A1 (en) | 2014-10-22 | 2016-04-28 | Merck Sharp & Dohme Corp. | Nargenicin compounds and uses thereof as antibacterial agents |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0352781A2 (en) * | 1988-07-29 | 1990-01-31 | The Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
WO1993009103A1 (en) * | 1991-11-01 | 1993-05-13 | The Upjohn Company | Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents |
WO2004029066A2 (en) * | 2002-09-26 | 2004-04-08 | Rib-X Pharmaceuticals, Inc. | Bifunctional heterocyclic compounds and methods of making and using same |
WO2005061468A1 (en) * | 2003-12-17 | 2005-07-07 | Rib-X Pharmaceuticals, Inc. | Halogenated biaryl heterocyclic compounds and methods of making and using the same |
WO2006133397A2 (en) * | 2005-06-08 | 2006-12-14 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of triazoles |
-
2007
- 2007-05-15 WO PCT/US2007/011722 patent/WO2007133803A2/en active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0352781A2 (en) * | 1988-07-29 | 1990-01-31 | The Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
WO1993009103A1 (en) * | 1991-11-01 | 1993-05-13 | The Upjohn Company | Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents |
WO2004029066A2 (en) * | 2002-09-26 | 2004-04-08 | Rib-X Pharmaceuticals, Inc. | Bifunctional heterocyclic compounds and methods of making and using same |
WO2005061468A1 (en) * | 2003-12-17 | 2005-07-07 | Rib-X Pharmaceuticals, Inc. | Halogenated biaryl heterocyclic compounds and methods of making and using the same |
WO2006133397A2 (en) * | 2005-06-08 | 2006-12-14 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of triazoles |
Non-Patent Citations (1)
Title |
---|
WEIDNER-WELLS M A ET AL: "The synthesis and antimicrobial evaluation of a new series of isoxazolinyl oxazolidinones", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, vol. 14, no. 12, 21 June 2004 (2004-06-21), pages 3069 - 3072, XP004841345, ISSN: 0960-894X * |
Also Published As
Publication number | Publication date |
---|---|
WO2007133803A2 (en) | 2007-11-22 |
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