WO2005005398A3 - Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof - Google Patents
Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof Download PDFInfo
- Publication number
- WO2005005398A3 WO2005005398A3 PCT/US2004/020734 US2004020734W WO2005005398A3 WO 2005005398 A3 WO2005005398 A3 WO 2005005398A3 US 2004020734 W US2004020734 W US 2004020734W WO 2005005398 A3 WO2005005398 A3 WO 2005005398A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- derivatives
- group substituted
- cyclopropyl group
- substituted oxazolidinone
- species
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Abstract
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2530140A CA2530140C (en) | 2003-07-02 | 2004-06-29 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof |
DE602004027811T DE602004027811D1 (en) | 2003-07-02 | 2004-06-29 | CYCLOPROPYL GROUP SUBSTITUTED OXAZOLIDINONANTIBIOTICS AND DERIVATIVES THEREOF |
CN200480019102.2A CN1816548B (en) | 2003-07-02 | 2004-06-29 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof |
AU2004256083A AU2004256083B2 (en) | 2003-07-02 | 2004-06-29 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof |
EP04777196A EP1646629B1 (en) | 2003-07-02 | 2004-06-29 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof |
AT04777196T ATE471937T1 (en) | 2003-07-02 | 2004-06-29 | CYCLOPROPYL GROUP SUBSTITUTED OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF |
BRPI0411688-7A BRPI0411688A (en) | 2003-07-02 | 2004-06-29 | cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof |
NZ544237A NZ544237A (en) | 2003-07-02 | 2004-06-29 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof |
JP2006517736A JP4607107B2 (en) | 2003-07-02 | 2004-06-29 | Cyclopropyl-substituted oxazolidinone antibiotics and their derivatives |
MXPA06000228A MXPA06000228A (en) | 2003-07-02 | 2004-06-29 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof. |
IS8178A IS8178A (en) | 2003-07-02 | 2005-12-13 | Oxazolidinone Fukuyl substituted with cyclopropyl group and their derivatives |
IL172785A IL172785A0 (en) | 2003-07-02 | 2005-12-22 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof |
NO20060558A NO20060558L (en) | 2003-07-02 | 2006-02-02 | Cyclopropyl group substituted oxazolidinone antibiotic agents and derivatives thereof |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48390403P | 2003-07-02 | 2003-07-02 | |
US60/483,904 | 2003-07-02 | ||
US54698404P | 2004-02-24 | 2004-02-24 | |
US60/546,984 | 2004-02-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005005398A2 WO2005005398A2 (en) | 2005-01-20 |
WO2005005398A3 true WO2005005398A3 (en) | 2005-04-28 |
Family
ID=34068173
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/020734 WO2005005398A2 (en) | 2003-07-02 | 2004-06-29 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof |
Country Status (23)
Country | Link |
---|---|
US (2) | US7462633B2 (en) |
EP (1) | EP1646629B1 (en) |
JP (1) | JP4607107B2 (en) |
KR (1) | KR20060113625A (en) |
AR (1) | AR044990A1 (en) |
AT (1) | ATE471937T1 (en) |
AU (1) | AU2004256083B2 (en) |
BR (1) | BRPI0411688A (en) |
CA (1) | CA2530140C (en) |
CL (1) | CL2004001678A1 (en) |
DE (1) | DE602004027811D1 (en) |
EC (1) | ECSP056257A (en) |
IL (1) | IL172785A0 (en) |
IS (1) | IS8178A (en) |
MA (1) | MA27938A1 (en) |
MX (1) | MXPA06000228A (en) |
MY (1) | MY140137A (en) |
NO (1) | NO20060558L (en) |
NZ (1) | NZ544237A (en) |
PE (1) | PE20050732A1 (en) |
RU (1) | RU2348628C2 (en) |
TW (1) | TW200510421A (en) |
WO (1) | WO2005005398A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2794494C2 (en) * | 2016-10-17 | 2023-04-19 | МЕРК ШАРП И ДОУМ ЭлЭлСи | Oxazolidinone compounds and methods of their application as antibacterial agents |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002360238B2 (en) * | 2001-04-17 | 2007-11-15 | Kyorin Pharmaceutical Co., Ltd. | Bicyclo[3,1,0]hexane containing oxazolidinone antibiotic and derivatives thereof |
WO2005019211A2 (en) * | 2003-06-03 | 2005-03-03 | Rib-X Pharmaceuticals, Inc. | Biaryl heterocyclic compounds and methods of making and using the same |
US8324398B2 (en) | 2003-06-03 | 2012-12-04 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of biaryl oxazolidinones |
EP1646629B1 (en) | 2003-07-02 | 2010-06-23 | Merck Sharp & Dohme Corp. | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof |
US20070293493A1 (en) * | 2003-07-02 | 2007-12-20 | Milton Hammond | Oxazolidinone antibiotics and derivatives thereof |
US7129259B2 (en) * | 2003-12-17 | 2006-10-31 | Rib-X Pharmaceuticals, Inc. | Halogenated biaryl heterocyclic compounds and methods of making and using the same |
KR100854211B1 (en) | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | Novel oxazolidinone derivatives, a process for the preparation thereof and pharmaceutical composition comprising the same for antibiotics |
EP1799677A1 (en) * | 2004-10-08 | 2007-06-27 | Ranbaxy Laboratories Limited | Oxazolidinone derivatives as antimicrobials |
JP5534497B2 (en) | 2005-06-08 | 2014-07-02 | メリンタ セラピューティクス,インコーポレイテッド | Method for synthesizing triazoles |
US20090018123A1 (en) * | 2005-06-20 | 2009-01-15 | Milind D Sindkhedkar | Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation |
US7838526B2 (en) * | 2005-08-05 | 2010-11-23 | Esther Baldinger | Method of treating neurological disorders |
AR054608A1 (en) * | 2005-08-08 | 2007-06-27 | Actelion Pharmaceuticals Ltd | OXAZOLIDINONE DERIVATIVES LINKED TO QUINOLONES AS ANTIBACTERIALS |
AU2008260647A1 (en) * | 2007-05-23 | 2008-12-11 | Merck Sharp & Dohme Corp. | Cyclopropyl pyrrolidine orexin receptor antagonists |
US8604209B2 (en) | 2008-10-10 | 2013-12-10 | Trius Therapeutics, Inc. | Methods for preparing oxazolidinones and compositions containing them |
KR101739923B1 (en) | 2009-02-03 | 2017-05-25 | 머크 샤프 앤드 돔 코포레이션 | Crystalline form of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
US8580767B2 (en) * | 2009-05-28 | 2013-11-12 | Trius Therapeutics, Inc. | Oxazolidinone containing dimer compounds, compositions and methods to make and use |
KR20120106697A (en) | 2009-06-26 | 2012-09-26 | 파나세아 바이오테크 리미티드 | Novel azabicyclohexanes |
BR112013007566A2 (en) | 2010-09-28 | 2016-08-02 | Panacea Biotec Ltd | new bicyclic compounds |
WO2017066964A1 (en) * | 2015-10-22 | 2017-04-27 | Merck Sharp & Dohme Corp. | Oxazolidinone compounds and methods of use thereof as antibacterial agents |
Citations (7)
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EP0352781A2 (en) * | 1988-07-29 | 1990-01-31 | The Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
WO1994013649A1 (en) * | 1992-12-08 | 1994-06-23 | The Upjohn Company | Tropone-substituted phenyloxazolidinone antibacterial agents |
US5736545A (en) * | 1996-02-26 | 1998-04-07 | Pharmacia & Upjohn Company | Azolyl piperazinyl phenyl oxazolidinone antimicrobials |
WO2001094342A1 (en) * | 2000-06-05 | 2001-12-13 | Dong A Pharm. Co., Ltd. | Novel oxazolidinone derivatives and a process for the preparation thereof |
WO2003027083A1 (en) * | 2001-04-17 | 2003-04-03 | Merck & Co., Inc. | Bicyclo[3,1,0]hexane containing oxazolidinone antibiotic and derivatives thereof |
WO2004048350A2 (en) * | 2002-11-28 | 2004-06-10 | Astrazeneca Ab | Oxazolidinones as antibacterial agents |
US20040147760A1 (en) * | 2002-02-25 | 2004-07-29 | Thomas Richard Charles | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
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US4053593A (en) * | 1975-11-26 | 1977-10-11 | Lew Frumoff | Medical product combining antimicrobial, antiporasitic and vitamin complex |
AU667198B2 (en) * | 1991-11-01 | 1996-03-14 | Pharmacia & Upjohn Company | Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents |
TW286317B (en) | 1993-12-13 | 1996-09-21 | Hoffmann La Roche | |
DE4425612A1 (en) * | 1994-07-20 | 1996-04-04 | Bayer Ag | 6-membered nitrogen-containing heteroaryl oxazolidinones |
HRP960159A2 (en) * | 1995-04-21 | 1997-08-31 | Bayer Ag | Benzocyclopentane oxazolidinones containing heteroatoms |
ATE204874T1 (en) | 1995-05-11 | 2001-09-15 | Upjohn Co | SPIROCYCLIC AND BICYCLIC DIAZINYL AND CARBAZINYLOXAZOLIDINONES |
WO2000070758A1 (en) | 1999-05-14 | 2000-11-23 | Kabushiki Kaisha Toshiba | Surface acoustic wave device |
US6608081B2 (en) * | 1999-08-12 | 2003-08-19 | Ortho-Mcneil Pharmaceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
JP2003522763A (en) | 2000-02-10 | 2003-07-29 | ファルマシア・アンド・アップジョン・カンパニー | Oxazolidinone thioamide with piperazine amide substituent |
GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
BR0112826A (en) * | 2000-07-17 | 2003-06-24 | Ranbaxy Lab Ltd | Oxazolidinone derivatives as antimicrobials |
AU2001293163A1 (en) * | 2000-09-27 | 2002-04-08 | Lynx Therapeutics, Inc. | Method for determining relative abundance of nucleic acid sequences |
US6689769B2 (en) | 2000-12-21 | 2004-02-10 | Pharmacia & Upjohn Company | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections |
YU52403A (en) | 2000-12-26 | 2006-03-03 | Dr.Reddy's Research Foundation | Heterocyclic compounds having antibacterial activity, process for their preparation and pharmaceutical compositions containing them |
EP1448536A1 (en) | 2001-11-29 | 2004-08-25 | Merck & Co., Inc. | Cyclopropyl-containing oxazolidinone antibiotics and derivatives thereof |
CN1155585C (en) | 2001-12-19 | 2004-06-30 | 中国医学科学院医药生物技术研究所 | 3,5-substituted oxazolidinone derivative and its preparing process and application |
TW200302095A (en) | 2002-01-25 | 2003-08-01 | Upjohn Co | Oxazolidinone cotherapy |
AR038536A1 (en) | 2002-02-25 | 2005-01-19 | Upjohn Co | N-ARIL-2-OXAZOLIDINONA-5- CARBOXAMIDS AND ITS DERIVATIVES |
US7473699B2 (en) | 2002-02-28 | 2009-01-06 | Astrazeneca Ab | 3-cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and their use as antibacterial agents |
BR0310074A (en) | 2002-05-15 | 2005-03-08 | Ranbaxy Lab Ltd | Polymorphic forms of phenyl oxazolidinone derivatives |
US6875784B2 (en) | 2002-10-09 | 2005-04-05 | Pharmacia & Upjohn Company | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives |
TW200500360A (en) * | 2003-03-01 | 2005-01-01 | Astrazeneca Ab | Hydroxymethyl compounds |
WO2004089943A1 (en) | 2003-04-09 | 2004-10-21 | Pharmacia & Upjohn Company Llc | Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues |
EP1625124A1 (en) | 2003-05-06 | 2006-02-15 | Ranbaxy Laboratories, Ltd. | Oxazolidinone derivatives as antimicrobials |
EP1656357A1 (en) * | 2003-07-02 | 2006-05-17 | Merck & Co., Inc. | Oxazolidinone antibiotics and derivatives thereof |
US20070293493A1 (en) * | 2003-07-02 | 2007-12-20 | Milton Hammond | Oxazolidinone antibiotics and derivatives thereof |
EP1646629B1 (en) * | 2003-07-02 | 2010-06-23 | Merck Sharp & Dohme Corp. | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof |
JP2007521283A (en) * | 2003-07-02 | 2007-08-02 | メルク アンド カンパニー インコーポレーテッド | Oxazolidinone antibiotics and derivatives thereof substituted with cyclopropyl groups |
-
2004
- 2004-06-29 EP EP04777196A patent/EP1646629B1/en active Active
- 2004-06-29 RU RU2005140379/04A patent/RU2348628C2/en not_active IP Right Cessation
- 2004-06-29 DE DE602004027811T patent/DE602004027811D1/en active Active
- 2004-06-29 AT AT04777196T patent/ATE471937T1/en not_active IP Right Cessation
- 2004-06-29 WO PCT/US2004/020734 patent/WO2005005398A2/en active Search and Examination
- 2004-06-29 US US10/878,637 patent/US7462633B2/en not_active Expired - Fee Related
- 2004-06-29 AU AU2004256083A patent/AU2004256083B2/en not_active Ceased
- 2004-06-29 NZ NZ544237A patent/NZ544237A/en unknown
- 2004-06-29 CA CA2530140A patent/CA2530140C/en not_active Expired - Fee Related
- 2004-06-29 BR BRPI0411688-7A patent/BRPI0411688A/en not_active IP Right Cessation
- 2004-06-29 MX MXPA06000228A patent/MXPA06000228A/en active IP Right Grant
- 2004-06-29 JP JP2006517736A patent/JP4607107B2/en not_active Expired - Fee Related
- 2004-06-29 KR KR1020067000071A patent/KR20060113625A/en not_active Application Discontinuation
- 2004-07-01 MY MYPI20042639A patent/MY140137A/en unknown
- 2004-07-01 CL CL200401678A patent/CL2004001678A1/en unknown
- 2004-07-01 AR ARP040102330A patent/AR044990A1/en unknown
- 2004-07-01 PE PE2004000629A patent/PE20050732A1/en not_active Application Discontinuation
- 2004-07-02 TW TW093120081A patent/TW200510421A/en unknown
-
2005
- 2005-12-13 IS IS8178A patent/IS8178A/en unknown
- 2005-12-22 IL IL172785A patent/IL172785A0/en unknown
- 2005-12-28 EC EC2005006257A patent/ECSP056257A/en unknown
-
2006
- 2006-01-30 MA MA28763A patent/MA27938A1/en unknown
- 2006-02-02 NO NO20060558A patent/NO20060558L/en not_active Application Discontinuation
-
2007
- 2007-01-22 US US11/655,840 patent/US7582659B2/en not_active Expired - Fee Related
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0352781A2 (en) * | 1988-07-29 | 1990-01-31 | The Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
WO1994013649A1 (en) * | 1992-12-08 | 1994-06-23 | The Upjohn Company | Tropone-substituted phenyloxazolidinone antibacterial agents |
US5523403A (en) * | 1992-12-08 | 1996-06-04 | The Upjohn Company | Tropone-substituted phenyloxazolidinone antibacterial agents |
US5736545A (en) * | 1996-02-26 | 1998-04-07 | Pharmacia & Upjohn Company | Azolyl piperazinyl phenyl oxazolidinone antimicrobials |
WO2001094342A1 (en) * | 2000-06-05 | 2001-12-13 | Dong A Pharm. Co., Ltd. | Novel oxazolidinone derivatives and a process for the preparation thereof |
WO2003027083A1 (en) * | 2001-04-17 | 2003-04-03 | Merck & Co., Inc. | Bicyclo[3,1,0]hexane containing oxazolidinone antibiotic and derivatives thereof |
US20040147760A1 (en) * | 2002-02-25 | 2004-07-29 | Thomas Richard Charles | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
WO2004048350A2 (en) * | 2002-11-28 | 2004-06-10 | Astrazeneca Ab | Oxazolidinones as antibacterial agents |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2794494C2 (en) * | 2016-10-17 | 2023-04-19 | МЕРК ШАРП И ДОУМ ЭлЭлСи | Oxazolidinone compounds and methods of their application as antibacterial agents |
Also Published As
Publication number | Publication date |
---|---|
AU2004256083A1 (en) | 2005-01-20 |
JP2007521281A (en) | 2007-08-02 |
MXPA06000228A (en) | 2006-06-27 |
IL172785A0 (en) | 2006-06-11 |
EP1646629B1 (en) | 2010-06-23 |
IS8178A (en) | 2005-12-13 |
JP4607107B2 (en) | 2011-01-05 |
US7462633B2 (en) | 2008-12-09 |
TW200510421A (en) | 2005-03-16 |
US20070203187A1 (en) | 2007-08-30 |
NO20060558L (en) | 2006-02-02 |
CA2530140A1 (en) | 2005-01-20 |
AR044990A1 (en) | 2005-10-12 |
ATE471937T1 (en) | 2010-07-15 |
CA2530140C (en) | 2010-11-09 |
NZ544237A (en) | 2008-09-26 |
DE602004027811D1 (en) | 2010-08-05 |
AU2004256083B2 (en) | 2007-10-11 |
PE20050732A1 (en) | 2005-11-02 |
US7582659B2 (en) | 2009-09-01 |
WO2005005398A2 (en) | 2005-01-20 |
MY140137A (en) | 2009-11-30 |
US20050038092A1 (en) | 2005-02-17 |
CL2004001678A1 (en) | 2005-05-20 |
RU2348628C2 (en) | 2009-03-10 |
ECSP056257A (en) | 2006-04-19 |
BRPI0411688A (en) | 2006-12-26 |
EP1646629A2 (en) | 2006-04-19 |
MA27938A1 (en) | 2006-06-01 |
RU2005140379A (en) | 2007-08-10 |
KR20060113625A (en) | 2006-11-02 |
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