WO2000019919A1 - Laser handpiece having zero time positioning system - Google Patents
Laser handpiece having zero time positioning system Download PDFInfo
- Publication number
- WO2000019919A1 WO2000019919A1 PCT/US1999/023302 US9923302W WO0019919A1 WO 2000019919 A1 WO2000019919 A1 WO 2000019919A1 US 9923302 W US9923302 W US 9923302W WO 0019919 A1 WO0019919 A1 WO 0019919A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fiber
- handpiece
- sensor
- optical fiber
- laser
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
- A61B18/24—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor with a catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00132—Setting operation time of a device
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00238—Type of minimally invasive operation
- A61B2017/00243—Type of minimally invasive operation cardiac
- A61B2017/00247—Making holes in the wall of the heart, e.g. laser Myocardial revascularization
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00345—Vascular system
- A61B2018/00351—Heart
- A61B2018/00392—Transmyocardial revascularisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/06—Measuring instruments not otherwise provided for
- A61B2090/062—Measuring instruments not otherwise provided for penetration depth
Definitions
- the present disclosure relates generally to a laser ablation device for surgical use More specifically, the present disclosure relates to a laser ablation handpiece having a zero time positioning system designed to provide an accurate location of the distal end of an optical fiber prior to starting a surgical procedure.
- TMR transmyocardial revascularization
- TMR is a procedure for producing channels of small diameters within the myocardium, which channels extend into the ventricle Such channels are believed to facilitate delivery of blood directly from the ventricle to oxygen starved areas of the heart TMR is typically used on patients with ischemic heart disease who are not candidates for coronary artery bypass or percutaneous transluminal angioplasty
- channels are created from the epicardium, through the myocardium and endocardium and into the ventricle, with each channel being of sufficiently small diameter such that the end portions of the channels at the epicardium can be closed by blood clotting
- the channels are preferably created by employing either a mechanical coring apparatus or an advancing lasing device, such as an optical fiber In the case of the latter, the optical fiber is advanced through a handpiece in proximity to the heart tissue and a laser is fired to transmit laser energy through the fiber to ablate the heart tissue
- a TMR procedure is generally performed either percutaneously or by exposing the heart via a thoracotomy, i e , an open procedure
- a laser fiber is navigated through the tortuous arterial pathways to reach a ventricular cavity
- Laser energy is then transmitted through the laser fiber to create TMR channels within the heart tissue
- the surgeon places the optical fiber in proximity to the epicardium and subsequently fires the laser to create TMR channels within the heart tissue
- the surgeon Before laser energy is transmitted to ablate heart tissue, i e , at time zero, it is desirable for the surgeon to know the location of the distal end of the fiber This location information is useful in letting the surgeon know if the fiber has exited the handpiece and if so, how much fiber has exited the handpiece This information is necessary to prevent premature firing of the laser, i.e., firing the laser before the fiber has exited the handpiece Premature firing could damage the handpiece and other components therein, including the fiber sheath Additionally, if too much fiber exits the handpiece prior to the TMR procedure, heart tissue in proximity to the handpiece may be inadvertently scratched or pierced It is preferred for the surgeon to know the location of the distal end within 0.50 mm for open procedures and 0 25 mm for percutaneous procedures
- a laser ablation device having a zero time positioning system
- the laser ablation device includes a handpiece having a sensor adjacent the distal end of a tube from which an optical fiber exits the handpiece This sensor senses the fiber's position within the tube by detecting a signal such as the red light which emanates from the fiber prior to firing Upon detection of the red signal, the sensor sends feedback information to a control module which can suspend further advancement of the fiber
- the sensor could include an infrared detector, a photodetector, or a heat/temperature sensor
- a sensor is provided for detecting a marker on the fiber sheath as the fiber sheath moves relative to the handpiece Upon detection of the marker, the sensor sends feedback information to the control module which can suspend further advancement of the fiber
- the distance from the distal end of the fiber to the marker and the position of the sensor can be arranged such that when the control module suspends advancement of the fiber, the fiber
- FIG 3 is an enlarged perspective view of the handpiece of the laser ablation device shown in FIG 1 ,
- FIG 4 is an enlarged perspective view with parts separated showing the various components of the handpiece
- FIG 4A is an enlarged perspective view of a light-detecting sensor
- FIG 5 is an enlarged perspective view of the distal end of the handpiece shown in FIG.
- FIG 6 is an enlarged perspective view of the distal end of the handpiece shown in FIG 1 with the articulating tube being in the articulating position
- FIGS 7-12 illustrate a TMR procedure using the laser ablation device of FIG 1,
- FIG 7 is a side view showing the articulating tube moved into the articulating position
- FIG 8 is a side view showing distal translation of an optical fiber through the articulating tube
- FIG 8A is an enlarged side view showing the optical fiber exiting the articulating tube
- FIG 9 is an enlarged side view in partial cross-section illustrating the fiber piercing the epicardium
- FIG 10 is an enlarged side view in partial cross-section illustrating the formation of a channel through heart tissue
- FIG 1 1 is an enlarged side view in partial cross-section illustrating the fiber withdrawn from the heart tissue
- FIG 12 is an enlarged side view of the handpiece illustrating the fiber retracted back into the articulating tube
- FIG 13 is a perspective view of an alternative laser ablation device
- FIG 13A is an enlarged perspective view of a marker positioned on an optical fiber of the laser ablation device of FIG 13,
- FIG 14 is an enlarged perspective view with parts separated showing the various components of the handpiece of the laser ablation dev ice of FIG 13
- FIG 15 is an enlarged perspective view of the handpiece of the laser ablation device of FIG. 13,
- FIG. 16 is an enlarged cross-sectional view showing a sensor within the handpiece detecting a marker positioned on the optical fiber of the laser ablation device of FIG. 13,
- FIG. 17 is an enlarged perspective view of the distal end of the handpiece shown in FIG.
- FIG. 18 is another alternative laser ablation device
- FIG. 19 is an enlarged perspective view of a marker on the optical fiber of the laser ablation device of FIG. 18;
- FIG. 20 is a cross-sectional view of an alternate handpiece for operating with the laser ablation device shown by FIG l, and
- FIG. 21 is an enlarged cross-sectional view of the area of detail circled in FIG 20
- a laser ablation device having a zero time positioning system is shown and designated generally by reference numeral 10
- Laser ablation device 10 is employed to perform a TMR procedure in accordance with the present disclosure
- Lasing device 10 is similar to lasing devices disclosed in copending, commonly assigned U.S. Patent Application Serial No 08/648,638 to Pacala et al , filed May 13, 1996, the subject matter of which is incorporated herein by reference Device 10 is capable of advancing a laser ablation member 12, e g., an optical fiber, optical fiber bundle or other laser energy transmission mechanism, through heart tissue while concomitantly outputting laser energy, where the advancement rate is coordinated with the magnitude of laser energy generated and with the pulsing frequency of the laser source It is contemplated that the advancement rate, the magnitude of laser energy generated, and the pulsing frequency of the laser source are automatically controlled by feedback control systems
- Laser ablation device 10 includes a handpiece 14, an optical fiber advancing mechanism 16, a laser generator 18, a foot operated actuator 20. a control module 22, and a zero time positioning system 27.
- Handpiece 14 includes an elongated, rigid tube 24 having an articulating tube 26 traverse therethrough.
- Zero time positioning system 27 includes at least one sensor 28 capable of detecting the red positioning light emanating from fiber 12 prior to firing of the laser generator 18 as further described below.
- the Max-30 excimer laser manufactured by Medolas of Germany and the Spectranetics CVX-300 excimer laser both transmit a red positioning light through the fiber prior to firing the laser. It is also contemplated that other signals could be utilized to activate the sensor. For example, sound, magnetic, electromagnetic, and chemical.
- Zero time positioning system 27 further includes circuitry within control module 22 for processing signals transmitted from sensor 28 via a wire 3 1 for determining when fiber 12 has exited articulating tube 26.
- Sensor 28 could include an infrared detector, a photodetector, or a heat/temperature sensor. It is also contemplated to utilize more than one sensor to position fiber 12 relative to handpiece 14.
- Laser generator 18 may be either a continuous wave laser or a pulsed, high energy laser, such as, for example, an excimer, C0 2 , Yag or an alexandrite laser.
- Optical fiber advancing mechanism 16 and laser generator 18 are operably connected to foot actuator 20.
- Optical fiber advancing mechanism 16 is of the type capable of precisely transmitting longitudinal motion to optical fiber 12 and to suspend advancement of fiber 12 upon detection of the red positioning light by sensor 28.
- the controlled longitudinal motion can be provided by one or more motors and preferably by one or more stepper motors which can deliver approximately four pounds of pushing force and 1.25 pounds of pull force to a 1.4 mm fiber bundle.
- foot actuator 20 After sensor 28 has detected the red positioning light, i.e., after time zero, foot actuator 20 is depressed to transmit laser energy through optical fiber 12 while fiber advancing mechanism 16 contemporaneously advances optical fiber 12 relative to handpiece 14. An electrical signal from foot actuator 20 actuates control module 22 which communicates with fiber advancing mechanism 16. Control module 22 is programmable and controls the motors or other suitable advancing structure in advancing mechanism 16 upon actuation of foot actuator 20.
- control module 22 is shown with a programmable computer 74 having a terminal 76 and a keyboard 78 for storing instructions required to operate advancing mechanism 16.
- Computer 74 may be programmed to suspend operation of advancing mechanism 16 when sensor 28 has detected the red positioning light and the fiber 12 has advanced a predetermined distance relative to handpiece 14.
- a toggle switch 35 may be provided on control module 22 to switch from an operation mode to a test mode. In a particular test mode, when foot actuator 20 is acted upon, flexible optical fiber 12 is moved sequentially from a retracted position, to a predetermined extended position, and back to the retracted position. It is contemplated that the predetermined extended position is the desired position of fiber 12 relative to handpiece 14 after sensor 28 has detected the red positioning light.
- Fiber advancing mechanism 16 is equipped with two limit switches which are set to control the amount of advancement of optical fiber 12 within the heart tissue. Preferably, these limit switches are automatic, however manual switches are also contemplated. Both limit switches are preempted by control module 22 during ablation if control module 22 determines that optical fiber 12 has entered the ventricle.
- the first limit switch is activated when optical fiber 12 is at a desired retracted position (i.e., a "home" position), wherein the mechanism that is retracting the fiber is caused to stop.
- Optical fiber 12 is in the retracted position unless foot actuator 20 is depressed or the test mode is activated.
- the exact retracted position can be selected by means of programming control module 22 or manually setting selector 36 which is a rotatable knob.
- the second limit switch limits/controls the maximum distance that optical fiber 12 can extend from handpiece 14.
- This limit switch may cooperatively operate with the zero time positioning system to receive feedback signals for determining the amount of advancement of fiber 12.
- External selector 36 is provided so that the operator can select the desired maximum extension of the distal end of optical fiber 12 from a distal end 30 of the articulating tube 26.
- selector 36 is in the form of a rotatable knob that can be set at selectable positions, wherein each position corresponds to a predetermined maximum longitudinal position of optical fiber 12. When the fiber reaches the selected maximum position, the fibers advancement is automatically terminated. It is contemplated that external selector 36 can be controlled automatically to control the amount of maximum extension of optical fiber 12 beyond handpiece 14.
- the operator can select maximum fiber extension positions so that the distal end of fiber 12 extends from the distal end of articulating tube 26 from between about 1.5 mm and about 50 mm, with the ability to select in increments of about 2.5 mm to about 5 mm.
- the zero time positioning system can send signals to computer 74 to compute the amount of advancement of fiber 12 by taking into consideration the rate of advancement of optical fiber 12 and the amount of extension of fiber 12 beyond the distal end of articulating tube 26 at time zero.
- the maximum extension position is preferably chosen to be slightly longer than the heart wall thickness for the particular patient such that fiber 12 will penetrate into the patient's ventricle. Once the maximum extended, position is reached, output of laser energy is automatically suspended.
- handpiece 14 includes housing 40 formed from molded housing half-sections 40a and 40b.
- Housing 40 has an elongated body 42 with a conically tapered section 44.
- Tube 24 traverses through housing 40 and rests against channel 80 formed within conically tapered section 44 of housing half-sections 40a and 40b.
- Articulating tube 26 which guides optical fiber 12 traverses a portion of tube 24 and is held within tube 24 by washers 82 and 84.
- Washer 84 includes a proximal end 85 which is press fit to a distal end of inner tube 88 which traverses rigid tube 24.
- a proximal end of articulating tube 26 is press fit to a distal end 87 of washer 84 for articulating tube 26 to be held within rigid tube 24.
- a proximal end of tube 24 is press fit within a first cavity 86 of slidable lever 46 as shown by broken line "A".
- Inner tube 88 traverses a second cavity 90, a channel (not shown) within wall 92 of lever 46 and tube 24.
- a distal end of inner tube 88 rests against channel 91 formed in housing 40 and flange 81 rests against groove 83 to fix inner tube 88 to housing 40.
- lever 46 When lever 46 is moved proximally along slot 89 formed between housing half-sections 40a and 40b, rigid tube 24 is moved proximally over inner tube 88 to cause articulating tube 26 to move into the articulating position as shown by FIGS. 6 and 7.
- Articulating tube 26 is manufactured from shape memory, alloy. Two ridged surfaces 47 are formed on lever 46 to facilitate grasping and moving of lever 46.
- At least one sensor 28 of the zero time positioning system 27 is fitted adjacent the distal end of articulating tube 26 and is electrically coupled to magnetic stripe 29 traversing articulating tube 26.
- Magnetic stripe 29 is coupled to a wire 31 which exits at the proximal end of handpiece 14.
- the wire 3 1 is connected to circuitry within control module 22 via an adapter 45 as shown by FIG. 3.
- a flexible support tube 48 surrounds the distal end of sheath 50 covering optical fiber 12 to reduce stress at the proximal end of handpiece 14.
- An elongated tubular portion 92 of metallic washer 94 is inserted within a distal end of support tube 48 to connect support tube 48 with handpiece 14. Washer 94 is housed within elongated body 42 of housing 40.
- Advancing mechanism 16 is then actuated by depressing foot actuator 20 to advance optical fiber 12 a predetermined distance beyond the distal end of articulating tube 26
- the predetermined distance can be programmed into control module 22 by using selector 36 as discussed above It is preferred that optical fiber 12 is advanced approximately 1.5 mm beyond articulating tube 26 as shown by FIG. 8.
- Zero positioning system 27 prevents fiber 12 from being advanced more than 1.5 mm by sending at least one feedback signal to control module 22 to suspend operation of advancing mechanism 16. Then at least one feedback signal is generated by sensor 28 after detecting the red positioning light emanating from fiber 12, as shown by FIG. 8 A.
- zero positioning system 27 ensures that the tip of fiber 12 is protruding approximately 1 5 mm at zero time or whatever distance the surgeon programmed control module 22 to suspend operation of advancing mechanism 16 after detection of the red positioning light.
- handpiece 14 is brought in proximity to the epicardium. It is preferred to position the distal end of optical fiber 12 either on the epicardium or to about 0.5 mm from the epicardium prior to firing laser generator 18 to initiate the TMR procedure.
- An alternate contemplated procedure is to position optical fiber 12 approximately 1.5 mm from the epicardium. With an advancement rate of 1 mm per second and a pulse rate of 30 pulses per second, upon further activation of the advancing mechanism 16, there are approximately 45 laser pulses prior to contact of fiber 12 with the epicardium. It may be desirable to fire laser generator 18 prior to contact of fiber 12 with the epicardium to loosen any debris on fiber 12 or between fiber 12 and the distal end of articulating tube 26
- fiber 12 is brought into contact with epicardium 60 without actuating laser generator 18 so as to mechanically pierce and thus separate the epicardial outer surface to facilitate the formation of a flap to prevent bleeding as shown by FIG. 9.
- epicardial and myocardial tissue 64 adjacent to the fiber tip is pushed aside This pushed aside tissue 64 will not be ablated with laser energy since foot actuator 20 has not yet been activated Tissue 64 will substantially return to its natural position following channel formation and act as a cap to reduce bleeding from the channel.
- the surgeon then commences TMR channel formation by depressing foot actuator 20.
- This initiates operation of laser generator 18 and advancing mechanism 16 to transmit laser energy from the tip of fiber 12 to ablate heart tissue while correspondingly advancing fiber 12
- Optical fiber 12 is advanced through the myocardium 62 and endocardium 66 until it reaches its maximum extended position corresponding to a predetermined distance as preset by selector 36 or until its advancement is suspended by control module 22 in response to feedback control signals or other parameters
- Optical fiber 12 is preferably advanced at a rate of between about 0 5 mm/sec (0.02 in/sec) to about 12.7 mm/sec (0.5 in/sec) with a laser power level of about 10 mJ/mm 2 to about 60 mJ/mm 2 and a pulsing frequency of about 5 Hz to about 100 Hz.
- the optical fiber is advanced at a rate of about 1 0 mm/sec to about 2 0 mm sec with a laser power level of between about 30 ml/mm 2 to about 40 mJ/mm 2 and a pulse frequency of about 50 Hz.
- the rate of advancement of the optical fiber is no greater than the rate of ablation of tissue in order to minimize mechanical tearing by the fiber
- the advancing mechanism can be manually set to advance the fiber at a rate greater than the ablation rate.
- Handpiece 14 is then is moved to another location on epicardium 60 to begin forming another channel.
- the overall procedure wherein dozens of channels are typically formed can thus be performed much faster as compared to prior an methods, since each channel 70 can be provided with a cap to prevent bleeding and fiber 12 is automatically retracted into articulating tube 26 following the formation of each TMR channel
- Laser ablation device 100 includes a handpiece 104, an optical fiber advancing mechanism 106, a laser generator 108, a foot operated actuator (not shown), a control module 1 12, and a zero time positioning system 1 13 Similarly to laser ablation device 10, laser ablation device 100 is capable of accurately positioning laser ablation member 12 a predetermined distance beyond the distal end of a handpiece at zero time and advancing laser ablation member 12 through heart tissue during a TMR procedure.
- handpiece 104 includes an elongated, rigid tube 1 14 having an articulating tube 1 16 traverse therethrough and other components similar to handpiece 14
- Sensor 1 18 is mounted within handpiece 104 on inner tube 1 10 to detect marker 120, as shown by FIG. 13N on sheath 122 as fiber 12 is advanced relative to handpiece 104
- At least one electrical signal is transmitted to control module 1 12 via wire 124 as sensor 1 18 detects marker 120 on sheath 122, as shown by FIG 16
- control module 1 12 can suspend operation of advancing mechanism 106
- marker 120 is positioned on sheath 122 where upon detection by sensor 1 18 fiber 12 has advanced approximately 1 5 mm beyond the distal end of articulating tube 1 16, as shown by letter "D" in FIG 17 It is contemplated that marker 120 is movable along sheath 122 to change the amount of advancement of fiber 12 from articulating tube 1 16 at time zero. It is further contemplated that sensor 1 18 is inductive for sensing a pattern created by marker 120 to emulate a magnetic Hall effect sensor.
- markers 202 are spaced apart on sheath 204 and are designed to create different signals as they are detected by a sensor (not shown) within handpiece 210 Each signal is indicative of a different marker 202 for relaying the amount of advancement of fiber 12 beyond the distal end of articulating tube 206 The signals are sent to control module 208 which determines the amount of advancement of fiber 12
- a handpiece for preferably performing TMR designated generally by reference numeral 300 and having a fiber positioning calibration mechanism 302
- Calibration mechanism 302 permits a surgeon to manually calibrate the position of the distal end of handpiece 300 relative to fiber 12
- calibration mechanism 302 includes an inner member 304 having an outer threaded surface 306 and an outer member 308 having an inner threaded bore 3 10
- Inner member 304 includes a bore 3 12 configured and dimensioned to matingly engage tubing 3 14 housing fiber 12 therein
- Tubing 3 14 is preferably made from hard plastics
- the surgeon grasps handpiece 300 with one hand and tubing 3 14 with the other hand and rotates inner member 304 within outer member 308 to move tubing 3 14 distally or proximally depending on the direction of rotation
- the distal end of handpiece 300 moves proximally relative to fiber 12.
- the maximum distance fiber 12 can be exposed by calibration mechanism 302 is 3 mm.
- the calibration mechanism 302 or a similar mechanism can be provided at the proximal end of tubing 3 14, such as at or near advancing mechanism 16. It is further contemplated to provide a marking on the distal end of tubing 3 14 to provide a reference point to easily determine the amount of displacement of fiber 12 with respect to handpiece 300.
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002346657A CA2346657A1 (en) | 1998-10-06 | 1999-10-06 | Laser handpiece having zero time positioning system |
EP99954763A EP1119301A1 (en) | 1998-10-06 | 1999-10-06 | Laser handpiece having zero time positioning system |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10329598P | 1998-10-06 | 1998-10-06 | |
US60/103,295 | 1998-10-06 |
Publications (2)
Publication Number | Publication Date |
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WO2000019919A1 true WO2000019919A1 (en) | 2000-04-13 |
WO2000019919A9 WO2000019919A9 (en) | 2000-08-31 |
Family
ID=22294435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/023302 WO2000019919A1 (en) | 1998-10-06 | 1999-10-06 | Laser handpiece having zero time positioning system |
Country Status (3)
Country | Link |
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EP (1) | EP1119301A1 (en) |
CA (1) | CA2346657A1 (en) |
WO (1) | WO2000019919A1 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002102266A1 (en) * | 2001-06-15 | 2002-12-27 | Diomed Inc. | Medical laser device |
US6986766B2 (en) | 2001-06-15 | 2006-01-17 | Diomed Inc. | Method of endovenous laser treatment |
WO2016090302A3 (en) * | 2014-12-05 | 2016-07-28 | Convergent Dental, Inc. | Systems and methods for alignment of a laser beam |
US10064569B2 (en) | 2011-08-09 | 2018-09-04 | Koninklijke Philips N.V. | Displacement feedback device and method for sensing or therapy delivery probes |
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US4716288A (en) * | 1980-11-01 | 1987-12-29 | Asahi Kogaku Kogyo Kabushiki Kaisha | Security device for detecting defects in transmitting fiber |
US5129896A (en) * | 1989-11-13 | 1992-07-14 | Hasson Harrith M | Holder to facilitate use of a laser in surgical procedures |
US5221279A (en) * | 1990-10-12 | 1993-06-22 | Surgical Laser Technologies, Inc. | Adjustable touch control handpiece |
US5275593A (en) * | 1992-04-30 | 1994-01-04 | Surgical Technologies, Inc. | Ophthalmic surgery probe assembly |
US5334207A (en) * | 1993-03-25 | 1994-08-02 | Allen E. Coles | Laser angioplasty device with magnetic direction control |
US5372595A (en) * | 1991-03-13 | 1994-12-13 | Georgetown University | Contact probe for laser cyclophotocoagulation |
-
1999
- 1999-10-06 CA CA002346657A patent/CA2346657A1/en not_active Abandoned
- 1999-10-06 EP EP99954763A patent/EP1119301A1/en not_active Withdrawn
- 1999-10-06 WO PCT/US1999/023302 patent/WO2000019919A1/en not_active Application Discontinuation
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
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US4716288A (en) * | 1980-11-01 | 1987-12-29 | Asahi Kogaku Kogyo Kabushiki Kaisha | Security device for detecting defects in transmitting fiber |
US5129896A (en) * | 1989-11-13 | 1992-07-14 | Hasson Harrith M | Holder to facilitate use of a laser in surgical procedures |
US5221279A (en) * | 1990-10-12 | 1993-06-22 | Surgical Laser Technologies, Inc. | Adjustable touch control handpiece |
US5372595A (en) * | 1991-03-13 | 1994-12-13 | Georgetown University | Contact probe for laser cyclophotocoagulation |
US5275593A (en) * | 1992-04-30 | 1994-01-04 | Surgical Technologies, Inc. | Ophthalmic surgery probe assembly |
US5334207A (en) * | 1993-03-25 | 1994-08-02 | Allen E. Coles | Laser angioplasty device with magnetic direction control |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002102266A1 (en) * | 2001-06-15 | 2002-12-27 | Diomed Inc. | Medical laser device |
US6981971B2 (en) | 2001-06-15 | 2006-01-03 | Diomed Inc. | Medical laser device |
US6986766B2 (en) | 2001-06-15 | 2006-01-17 | Diomed Inc. | Method of endovenous laser treatment |
US10064569B2 (en) | 2011-08-09 | 2018-09-04 | Koninklijke Philips N.V. | Displacement feedback device and method for sensing or therapy delivery probes |
WO2016090302A3 (en) * | 2014-12-05 | 2016-07-28 | Convergent Dental, Inc. | Systems and methods for alignment of a laser beam |
US9980789B2 (en) | 2014-12-05 | 2018-05-29 | Convergent Dental, Inc. | System and methods for alignment of a laser beam |
US10470843B2 (en) | 2014-12-05 | 2019-11-12 | Convergent Dental, Inc. | Systems and methods for alignment of a laser beam |
Also Published As
Publication number | Publication date |
---|---|
EP1119301A1 (en) | 2001-08-01 |
CA2346657A1 (en) | 2000-04-13 |
WO2000019919A9 (en) | 2000-08-31 |
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