USRE45962E1 - Device for the implantation and fixation of prosthetic valves - Google Patents
Device for the implantation and fixation of prosthetic valves Download PDFInfo
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- USRE45962E1 USRE45962E1 US14/454,334 US201414454334A USRE45962E US RE45962 E1 USRE45962 E1 US RE45962E1 US 201414454334 A US201414454334 A US 201414454334A US RE45962 E USRE45962 E US RE45962E
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- stent component
- heart valve
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- native heart
- valve
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2409—Support rings therefor, e.g. for connecting valves to tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/243—Deployment by mechanical expansion
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/243—Deployment by mechanical expansion
- A61F2/2433—Deployment by mechanical expansion using balloon catheter
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/2436—Deployment by retracting a sheath
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/958—Inflatable balloons for placing stents or stent-grafts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2002/9528—Instruments specially adapted for placement or removal of stents or stent-grafts for retrieval of stents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
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- A—HUMAN NECESSITIES
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
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- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
- A61F2230/0054—V-shaped
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- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/006—Additional features; Implant or prostheses properties not otherwise provided for modular
Definitions
- the present invention relates to a device for the transvascular implantation and fixation of prosthetic heart valves having a self-expanding heart valve stent with a prosthetic heart valve at its proximal end.
- a device of this type is, in principle, known to medical technology.
- biological or mechanical valve models are available to substitute for human heart valves which are usually fixedly sewn into the bed of the heart valve during a surgical procedure through an opening in the chest after removal of the diseased heart valve.
- the patient's circulation must be maintained by a heart-lung machine, whereby cardiac arrest is induced during the implantation of the prosthetic heart valve.
- cardiac arrest is induced during the implantation of the prosthetic heart valve.
- One approach provides for implanting a self-expanding prosthetic heart valve with an artificial heart valve and a collapsible and expandable stent connected to the heart valve into the human body by means of an appropriate catheter system.
- the catheter system is used to guide such a self-expanding prosthetic heart valve through a femoral artery or vein to its site of implantation at the heart.
- the stent which consists for example of a plurality of self-expanding stent segments which can be bent relative one another in the longitudinal direction, can then be successively expanded.
- anchoring hooks can for example support the anchoring of the prosthetic heart valve at least in the respective blood vessel close to the heart.
- the actual prosthetic heart valve itself is thereby in the direct proximal area of the stent.
- a device for fastening and anchoring prosthetic heart valves which is essentially formed from wire-shaped interconnected elements.
- the device provides for using various different arched elements in order to attain a secure retention and support for the prosthetic heart valve.
- the device described in this printed publication makes use of three identical pairs of arched elements, offset from one another by 120°. These arched elements are interconnected by means of solid articulations, whereby the solid articulations fulfill the function of pivot bearings.
- Additional arched elements bent opposite to each other are furthermore provided which form rocker arms as equal in length as possible in order to achieve a secure anchoring of the arched elements even when subject to peristaltic actions on the heart and blood vessels and a solid sealing for an implanted and anchored prosthetic heart valve.
- an implantation malalignment of a less than optimally positioned prosthetic heart valve can lead to, for example, leakage or valvular regurgitation, which puts a substantial burden on the ventricle.
- a prosthetic heart valve be implanted too high above the actual heart valve plane, this can lead to occlusion of the coronary artery origination (coronaries) and thus to a fatal coronary ischemia with myocardiac infarction. It is therefore imperative for an implanted prosthetic heart valve to meet all the respective requirements for both the accuracy of the lateral positioning as well as the angular positioning.
- the prosthesis is usually introduced using a guide wire and catheters, whereby conventional balloon catheters can also be used.
- the prosthetic heart valve must be able to be maneuvered as much as possible in the respective coronary artery during the implantation procedure so as to ensure optimum positioning accuracy and, on the other hand, the implanted prosthesis must be able to be firmly anchored at its site of implantation in order to effectively prevent subsequent prosthesis misalignment.
- the present invention addresses the problem that the known devices for transvascular implantation and fixation of prosthetic heart valves are often not suitable for easily implanting a prosthetic heart valve in a patient's ventricle with the necessary positioning accuracy.
- the necessary lateral positioning accuracy and the angular position of the prosthetic heart valve can usually only be sufficiently guaranteed when the person performing the procedure has the corresponding experience.
- explanting a previously implanted prosthetic heart valve in a minimally-invasive procedure or accordingly correcting an incorrectly positioned prosthetic heart valve has to date only been possible with great effort, if at all.
- the present invention proposes a device which enables a prosthetic heart valve to be implanted into a patient in a minimally-invasive procedure in as simple a manner as possible, wherein an increased positioning accuracy to the prosthesis in the patient's ventricle can in particular be ensured.
- a device is to, in particular, reduce the risk of an incorrect deployment to the greatest extent possible.
- this task is solved by a device as described at the outset by the device having, in addition to the self-expanding heart valve stent with a prosthetic heart valve at its proximal end, a self-expanding positioning stent insertable into a position in the patient's aortic valve, which is configured separate from the heart valve stent, wherein the positioning stent and the heart valve stent are configured such that they each work in concert in their expanded states so that the positioning stent helps to hold the heart valve stent in a position relative the patient's heart valve predefined by the positioning stent.
- the device according to the invention exhibits an entire array of substantial advantages over the prosthetic heart valves known from the prior art and described above.
- the two-part configuration of the device in the design of the heart valve stent and the positioning stent configured separately therefrom can, in particular, greatly increase the positioning accuracy of the prosthetic heart valve in the patient's ventricle.
- the positioning stent hereby primarily assumes the function of determining the position of the prosthetic heart valve in the patient's ventricle as well as the function of anchoring or fixing the prosthesis at optimum placement.
- the prosthetic heart valve is not on or in the positioning stent, but instead configured separately from the positioning stent on the heart valve stent. This has the advantage that the dimensions of the positioning stent in its collapsed state are extremely small, which increases the stent's maneuverability.
- the heart valve stent primarily serves the inventive device only as a supporting structure for the prosthetic heart valve to be implanted. This function sharing enables both the positioning stent as well as the heart valve stent to be of relatively simple configuration. What can be achieved in particular is that compared to a stent on which both a prosthetic heart valve as well as means for positioning and fixing the prosthetic heart valve are arranged, the positioning stent can be configured to exhibit only relatively small dimensions in its collapsed state. Inserting the positioning stent in the patient's artery is thus—due to the better maneuverability achieved—substantially simpler. A direct consequence of this is increased positioning accuracy for the positioning stent.
- the device according to the invention is configured in such a manner that not until the positioning stent is positioned into the patient's artery and after aligning the stent with respect to a predefinable axial rotation and horizontal position relative an (old) heart valve of the patient is the heart valve stent configured separately from the positioning stent inserted into the artery or vein.
- the heart valve stent which has the prosthetic heart valve at its proximal end, independently orientates itself to the exactly-positioned positioning stent as fixed at the arterial wall.
- the heart valve stent is independently guided within the expanded positioning stent into the implantation position predefined by the positioning stent at which the prosthetic heart valve is in an optimum position relative the patient's old heart valve.
- the full expansion of the heart valve stent is induced, for example by an external manipulation, as a consequence of which the heart valve stent according to the invention interacts with the positioning stent in such a way that the heart valve stent, and thus also the prosthetic heart valve disposed at its proximal end, is positionally fixed into the implantation position.
- the positioning stent serves—in addition to the already mentioned function of defining the position for the prosthetic heart valve in the patient's ventricle and the function of anchoring or fixing the prosthesis at this position—also the function of guiding the heart valve stent into the optimum position for the prosthetic heart valve during the implantation procedure.
- the advantages attainable with the inventive device are obvious: in particular, an optimum positioning is enabled for the prosthetic heart valve in its final implanted position, whereby the alignment and fixing of the prosthetic heart valve ensues independently based on the co-operative action of the heart valve stent and the positioning stent.
- a position-contingent, inaccurate implantation of the prosthetic heart valve can hereby be excluded.
- the device is characterized by the implantation and anchoring of the prosthetic heart valve ensuing in a particularly simple manner.
- the positioning stent according to the invention is configured to be an insertable, self-expanding component in a patient's blood vessel, it can be inserted beforehand; i.e., prior to the actual implantation of the prosthetic heart valve disposed at the proximal end of the heart valve stent. It would thus be conceivable here for the positioning stent to first be brought into the aorta and optimally positioned and fixed there, whereby the heart valve stent with the prosthetic heart valve is thereafter introduced and inserted optimally by means of the positioning stent already in position and fixed there.
- both the heart valve stent as well as the positioning stent are configured to self-expand, which facilitates the respective introduction of these components. Because the positioning stent assuming the task of determining the position for the heart valve stent, the prosthetic heart valve disposed thereon respectively, can be configured to be substantially smaller in comparison to previous self-expanding prosthetic heart valves, the maneuverability of the positioning stent is increased considerably, which ultimately results in being able to select an extremely precise position at which the positioning stent is anchored relative the heart valve and one ideally adapted to the respective requirements.
- This advantage of exact positioning of the easily-maneuvered and minutely-configured positioning stent extends to the subsequent implantation of the prosthetic heart valve since the heart valve stent, at the proximal end of which the prosthetic heart valve is arranged, is held in the position defined by the (optimally positioned) positioning stent.
- the heart valve stent provides for the heart valve stent to be configured to be reversibly expandable and collapsible. It is thereby conceivable for the heart valve stent to be collapsed, for example via external manipulation, and extracted using an explantation catheter. Specifically, this embodiment enables the heart valve stent in collapsed form to be connectably received in a cartridge of a positioning catheter, an explantation catheter respectively.
- the positioning stent In order for the heart valve stent to be optimally inserted into a patient's blood vessel and positioned there in a predefined position relative the heart valve, it is necessary for the positioning stent to be as small as possible in its collapsed state so that the stent can be optimally navigated with as little impact as possible on the heart valve. This is achieved by the prosthetic heart valve implant not being affixed to the positioning stent but rather to the heart valve stent.
- the positioning stent is furthermore configured such that all the components of the stent in the collapsed state have a certain measure of pretensioning acting in a radially outward direction which effects the self-expansion following release from the cartridge.
- the positioning stent can then be implanted with the cartridge in conventional manner using a positioning stent catheter, for example through a femoral artery. Should the positioning stent be inaccurately deployed, for example if the positioning stent is not positioned precisely accurately in the patient's aorta, or when an explantation of the positioning stent is necessary for other reasons, it is provided for the positioning stent to be convertible from its expanded state back into its collapsed state. This is done for example by external manipulation using an implantation catheter. The positioning stent is thus fully reversibly withdrawable in the catheter, which enables the stent to be completely removed.
- the inventive device for transvascular implantation and fixation of prosthetic heart valves can advantageously provide for the positioning stent to have an anchorage at its proximal end, in particular an anchoring support, whereby this anchoring support is configured such that the positioning stent self-positions into a pre-defined position relative the patient's heart valve in its expanded state and is held by means of the anchoring support.
- the positioning stent is thereby configured such that the anchoring support is received in collapsed form in a cartridge connectable with a catheter.
- the anchoring support is thereby to be compressed such that it is pretensioned in a radially outward direction which effects the self-expansion following release from the cartridge.
- Configuring the positioning stent so that it self-positions into a given position relative the patient's heart valve in its expanded state and is held there by means of the anchoring support enables the position of the positioning stent and thus the position of the heart valve stent to be precisely definable beforehand so that inaccurate implantations, as can occur with the known solutions, can be excluded.
- the positioning stent'can advantageously furthermore exhibit pretensioning elements in order to radially pretension the positioning stent in its position defined by the anchorage.
- the pretensioning elements are thereby also configured to be reversible so that their pretensioning function can be countermanded by external manipulation, which enables the positioning stent to be collapsed and thus be retracted into a catheter, enabling the positioning stent to be removed completely.
- the anchoring support to have at least one support strut which is configured such that it self-positions into the pockets of the patient's heart valve in the expanded state of the positioning stent and thus fixes the orientation of the positioning stent relative the heart valve in the axial and horizontal direction.
- the support struts configured at the proximal end of the positioning stent implant independently in the pockets of the respective patient's heart valve during the implantation procedure, whereby the pockets of the heart valve form a counter bearing for counteracting the proximal insertion motion so that the anchoring supports can be precisely positioned laterally with the positioning stent.
- the pockets represent a guide per se for the support struts during insertion, this ensures at the same time that the anchoring support and the positioning stent can adopt a precise angular position.
- the heart valve stent configured separately from the positioning stent deployed with the help of, for example, a heart valve catheter.
- the heart valve stent exhibiting the prosthetic heart valve at its proximal end is then optimally implanted at the most favorable and ideal site by means of the positioning stent already having been exactly positioned and fixed.
- the support struts of the positioning stent are positioned at the patient's heart valve following implantation of the positioning stent. Because the positioning stent is of relatively simple configuration, since it for example does not comprise the prosthetic heart valve which is disposed separately from the positioning stent on the heart valve stent, the struts of the positioning stent can exhibit a relatively large radius, which entails a lesser risk of injury to the heart valve.
- the support strut disposed on an anchoring support or anchorage should be curved convexly and arcuately in the proximal direction because such a rounded form wards off injuries to the heart's blood vessel as well as facilitates the unfolding in the self-expansion process. With such a design, inserting the support struts into the pockets of the old heart valve is thus likewise easier without engendering any corresponding injuries to the tissue or the blood vessels of the region.
- Additional stabilizing struts can also be provided on the anchoring supports, which achieves increased fixedness following the self-expansion of the anchored anchoring supports.
- Such stabilizing struts can be advantageous since in order to benefit from the self-expansion effect required of an anchoring support for securely fixing the anchoring support with the positioning stent, accepting that the anchoring supports collapsed within a to cartridge during the introduction phase must be of the smallest volume possible, small cross-sections for the respective struts must be maintained.
- All the struts of an anchoring support should thereby be arranged, configured and dimensioned such that the successively ensuing release of the supporting struts and the other struts with the further elements provided on an anchoring support, as the case may be, can be achieved by the appropriate manipulation of cartridge and/or catheter. In so doing, the design of the cartridge or at least a portion of the cartridge should, of course, also be taken into consideration.
- each of the supporting struts disposed on an anchoring support should be provided.
- each of the supporting struts disposed on an anchoring support should be at an angular offset from one another.
- the supporting struts with their proximal members are then introduced into the pockets of an old heart valve in the implanted state and the old heart valve can then be tightly secured and fixed with the supporting struts.
- the stability of an implanted and fixed positioning stent can be optimally increased by means of at least one ring support, which can be an element on an anchoring support.
- a ring support which can be an element on an anchoring support.
- the heart valve stent After the positioning stent is positioned at the heart and held there by the anchorage, the heart valve stent is introduced. It is hereby advantageously provided for the heart valve stent to be configured such that the prosthetic heart valve in its expanded state presses the patient's heart valve against the aorta wall, whereby the at least one anchorage of the positioning stent positions between the aorta wall and the heart valve expanded by the prosthetic heart valve.
- the positioning stent In order to have the heart valve stent be held in a position defined by the positioning stent relative the patient's heart valve using the positioning stent, the positioning stent has at least one engaging element at its distal end.
- the heart valve stent should thereby exhibit a correspondingly complementary-configured retaining element at its distal end, whereby in the expanded state of the positioning stent and in the fully expanded state of the heart valve stent, the at least one retaining element forms a positive connection with the at least one engaging element of the positioning stent. This thus achieves the positioning of the prosthetic heart valve in the coronary artery in the position predefined by the positioning stent and it being held there by the positioning stent.
- engaging clips on the heart valve stent are thereby among the elements of the heart valve stent which are not released to expand until the heart valve stem is accurately inserted into its implantation deployment site at the patient's heart valve by means of the already implanted positioning stent.
- the engaging clips of the heart valve stent expand, they engage with the engaging elements of the positioning stent and thus hold the heart valve stent in the position given by the positioning stent.
- portions of the respective patient's old heart valve then each work into an anchoring strut of the positioning stent and the expanded prosthetic heart valve so that the respective portions of the old heart valve can be clamped and held between these elements following the successful expanding of the prosthetic heart valve, similar to how a sheet of paper is held between the brackets of a paper clip.
- the heart valve stent is in particular configured such that it does not adopt its fully expanded state, in which both the prosthetic heart valve as well as also the retaining element is released, until the heart valve stent is in the position as defined by the positioning stent.
- the heart valve stent is also advantageously configured to be reversible in its folding action, whereby the positive connection with the positioning stent is disengaged in the collapsed state. This thus allows the prosthetic heart valve disposed on the heart valve stent to again be explanted, for example in the case of an improper implantation, without also having to extract the positioning stent in order to do so.
- explantation elements can be provided at the distal end of the heart valve stent which work in concert with the heart valve stent such that when externally manipulated, for example, the explantation elements disengage the positive connection between the heart valve stent and the positioning stent, and the heart valve stent collapses.
- One advantageous realization of the explantation elements provides for their being engageable, for example by means of an explantation catheter, whereby retracting the explantation elements in the explantation catheter disengages the positive connection between the heart valve stent and the positioning stent, and the heart valve stent folds back up.
- the heart valve stent is advantageously accommodated in the collapsed state in a cartridge connectable to a heart valve stent catheter and/or explantation catheter, whereby a predefinable motion of the cartridge will release the heart valve stent.
- a predefinable first motion of the cartridge will only release the prosthetic heart valve to expand, whereby the retaining element of the heart valve stent is released by at least one second subsequent motion of the cartridge, the catheter respectively.
- the movements of a cartridge or individual parts of a cartridge to be realized can be a proximal and/or distal displacement, which can ensue in several successive stages, each covering different paths in order to successively release the corresponding parts for their respective expansion during implantation.
- a first movement for example, can be a distal retraction of the cartridge or a portion of a cartridge.
- a proximal movement of the cartridge or a portion of a cartridge can then be effected to re-collapse the already-expanded retaining elements acting radially outwardly with a pretensioning force, the prosthetic heart valve of the heart valve stent respectively, and to bring same into the interior of the cartridge so as to enable the device to be removed from the patient.
- Bowden cables or flexible push tubes guided through the interior of the catheter to the cartridge or to a portion of the cartridge can be used as the actuating elements for a manipulation and the associated displacing movement of the cartridge or individual parts of the cartridge.
- Such actuating elements can, however, also engage with fastening elements, for example eyelets, provided on the anchoring support.
- the solution according to the invention thus also provides the possibility of aborting prosthetic heart valve implantations which will be unsuccessful and removing the device again by withdrawing the catheter, whereby in so doing, the heart valve stent which has already expanded re-collapses again and can be guided back into a cartridge or a portion of a cartridge.
- the positioning stent to furthermore comprise anchoring elements, in particular hooks, in order to anchor the positioning stent in its predefinable position at the heart.
- anchoring elements in particular hooks
- the heart valve stent it would be conceivable for the heart valve stent to also comprise anchoring elements such as hooks, for example, in order to anchor the heart valve stent in the position in the aorta as predefined by the positioning stent. Both solutions ultimately serve the secure fixing of the implanted prosthetic heart valve at its site of implantation as predefined by the positioning stent.
- markers can be disposed on the positioning stent, in particular x-ray markers.
- the positioning stent and/or the heart valve stent can furthermore exhibit guiding means which are configured in such a manner that the heart valve stent is guided independently in the expanded positioning stent into the position predefined by the positioning stent.
- the guiding means can be configured as elements tapering to the distal end of the positioning stent, the heart valve stent respectively, so as to realize a self-adjusting of the heart valve stent in the positioning stent and thus into the position predefined by the positioning stent.
- the device according to the invention can also be used together with a balloon catheter.
- a balloon catheter With a balloon catheter, the old heart valve can be pushed away prior to the self-expansion of the anchoring support.
- FIG. 1 a preferred embodiment of a positioning stent of the device according to the invention in the inserted and expanded state;
- FIG. 2A a preferred embodiment of a heart valve stent of the device according to the invention in the expanded state
- FIG. 2B the heart valve stent of FIG. 2A in the implanted state
- FIG. 3A ,B one schematic representation each to illustrate the explantation process with a preferred embodiment of the heart valve stent
- FIG. 4 a detailed representation of the explantation elements provided on the heart valve stent, the positioning stent respectively, as well as their mode of operation.
- FIG. 1 shows a preferred embodiment of a positioning stent 20 for the device according to the invention in the inserted state.
- the positioning stent 20 is in its expanded state in the embodiment shown.
- the positioning stent 20 has an anchoring segment 21 ′ with anchoring supports 21 at its proximal end.
- the anchoring supports 21 are hereby configured such that they optimize themselves into the pockets T of the old heart valve relative to axial rotation as well as horizontal position.
- the positioning stent 20 is supported by means of anchoring supports 21 in pockets T of the old heart valve.
- the anchoring supports 21 themselves are connected to docking segment 23 by means of shoulders 22 .
- the docking segment 24 ′ of positioning stent 20 provided at its distal end, exhibits a plurality of engaging elements 24 which fix a heart valve stent to be implanted (not explicitly shown in FIG. 1 ).
- the positioning stent 20 is configured as a self-expanding component. Due to the simple configuration of positioning stent 20 , which essentially consists only of anchoring segment 21 ′, docking segment 24 ′ and shoulders 22 , the positioning stent 20 exhibits extremely small dimensions when in its collapsed state. Thus, when inserting positioning stent 20 , for example using a positioning stent catheter, the positioning stent 20 has very good maneuverability within aorta A. After positioning stent 20 has been inserted into aorta A, it is expanded, enabled, for example, by means of an external manipulation of the positioning stent catheter.
- the anchoring supports 21 of the expanded positioning stent 20 self-position into the pockets T of the patient's heart valve, whereby the alignment of the positioning stent 20 in the axial and horizontal direction is fixed relative the heart valve. So that the positioning stent 20 will expand independently, suitable pretensioning elements can be (optionally) provided. In the embodiment as shown, pretensioning elements are realized in the form of anchoring supports 21 .
- a heart valve stent 10 ( FIG. 2A ) disposed with a prosthetic heart valve 11 at its proximal end is inserted into positioning stent 20 . It expands subsequent to release and, in doing so, presses the old valve against the aorta wall, the positioning stent 20 respectively.
- FIG. 2A shows a heart valve stent 10 in the expanded state.
- the heart valve stent 10 has the prosthetic heart valve 11 at its proximal end and an anchoring segment 12 ′ comprising at least one retaining element 12 at its distal end.
- FIG. 2B provides a representation of how the heart valve stent 10 is held in the already positioned and fixed positioning stent 20 .
- the heart valve stent 10 is guided by guide elements 17 , 27 in positioning stent 20 relative to rotation and axial position such that the new heart valve is optimally positioned. Thereafter, further releasing of the heart valve stent 10 introduces its anchoring segment 12 ′ into docking segment 24 ′ ( FIG. 1 ) of the positioning stent 20 .
- the anchoring segment 12 ′ comprises retaining elements 12 which form a positive connection with the engaging elements 24 of the positioning stent 10 in order to position the prosthetic heart valve 11 in the position in the coronary artery as predefined by the positioning stent 20 and to hold same there by means of positioning stent 20 .
- the heart valve stent 10 of the present device does not have retaining clips to engage behind the old heart valve but rather engaging clips in the form of retaining elements 12 in the anchoring segment 12 ′ of heart valve stent 10 . These engaging clips interact with the engaging elements 24 disposed in the docking segment 24 ′ of positioning stent 20 .
- the advantage of this is that the heart valve stent 10 is commutably anchored in positioning stent 20 . By means of its self-expanding induced by guide means 17 , 27 , heart valve stent 10 independently slides inside positioning stent 20 and cannot slide any further.
- the guide means 17 , 27 are configured as elements tapering to the distal end of positioning stent 20 and/or heart valve stent 10 . Due to the special design of engaging elements 23 of positioning stent 20 and the retaining elements 12 of heart valve stent 10 as clips formed in zigzag fashion (Z-clips), a finer angular positioning of the heart valve stent 10 can in particular ensue. Both the positioning stent 20 as well as the heart valve stent 10 can be configured of individual segments, whereby the individual segments can be rotated relative one another. This increases flexibility when inserting the two stents into the aorta. It is in particular possible to realize a finer angular positioning to heart valve stent 10 .
- the segmented configuration is also of advantage with respect to the collapsing of the heart valve stent and the positioning stent since the segmented stents in collapsed state can be housed compressed within a catheter.
- FIGS. 3A, 3B and 4 are schematic representations of how the heart valve stent 10 in the already positioned and implanted positioning stent 20 can be explanted.
- the mechanically stable connection between the positioning stent 20 and the heart valve stent 10 as described above can be disengaged again by external manipulation. This can be realized, for example, by using a catheter 30 with a cartridge 33 affixed thereto to engage explantation elements 13 . After retracting the explantation elements 13 into the variable funnel-shaped explantation catheter 30 , the heart valve stent 10 is pulled into same and can thus be replaced with a new one.
- the positioning stent 20 remains as a marking and anchoring base for a new heart valve stent 10 .
- Positioning stent 20 can, of course, also be explanted in a similar procedure.
- the docking segment 24 ′ of the positioning stent can comprise eyelets or nubs to which the explantation catheter 30 is to be affixed in order to effect such an explantation. Attaching to eyelets is possible via preferably three to six eyelets and three to six loops which are subsequently pulled out of the eyelets.
- the positioning stent 20 as well as the heart valve stent 10 is in particular completely reversibly withdrawable in the catheter, which enables the complete removal of the positioning stent and/or the heart valve stent.
- the disengaging of the mechanically stable connection between positioning stent 20 and heart valve stent 10 by means of external manipulation, in the case of valve dysfunction for example, is possible when the previously implanted heart valve stent 10 exhibits a retrievable structure suitable for this purpose.
- the positioning stent 20 is made from a solid mesh (wire, polymer, etc.) or produced in a laser-cutting process. Applicable as suitable materials for the positioning stent are NiTi, high-grade steel or biocompatible plastics. For spatial orientation, x-ray markers can furthermore be disposed on positioning stent 20 .
Abstract
Description
Claims (28)
Priority Applications (1)
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US14/454,334 USRE45962E1 (en) | 2005-10-28 | 2014-08-07 | Device for the implantation and fixation of prosthetic valves |
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US11/589,570 US8092521B2 (en) | 2005-10-28 | 2006-10-30 | Device for the implantation and fixation of prosthetic valves |
US13/315,913 US8551160B2 (en) | 2005-10-28 | 2011-12-09 | Device for the implantation and fixation of prosthetic valves |
US14/454,334 USRE45962E1 (en) | 2005-10-28 | 2014-08-07 | Device for the implantation and fixation of prosthetic valves |
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US14/020,497 Active US9044320B2 (en) | 2005-10-28 | 2013-09-06 | Device for the implantation and fixation of prosthetic valves |
US14/087,316 Active US8834561B2 (en) | 2005-10-28 | 2013-11-22 | Device for the implantation and fixation of prosthetic valves |
US14/454,334 Active USRE45962E1 (en) | 2005-10-28 | 2014-08-07 | Device for the implantation and fixation of prosthetic valves |
US14/454,285 Active 2027-05-31 USRE45790E1 (en) | 2005-10-28 | 2014-08-07 | Device for the implantation and fixation of prosthetic valves |
US14/708,892 Active US9402717B2 (en) | 2005-10-28 | 2015-05-11 | Device for the implantation and fixation of prosthetic valves |
US15/195,625 Active US9855142B2 (en) | 2005-10-28 | 2016-06-28 | Device for the implantation and fixation of prosthetic valves |
US15/821,012 Active US10363134B2 (en) | 2005-10-28 | 2017-11-22 | Device for the implantation and fixation of prosthetic valves |
US16/442,793 Active 2027-10-10 US11116628B2 (en) | 2005-10-28 | 2019-06-17 | Device for the implantation and fixation of prosthetic valves |
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US14/020,497 Active US9044320B2 (en) | 2005-10-28 | 2013-09-06 | Device for the implantation and fixation of prosthetic valves |
US14/087,316 Active US8834561B2 (en) | 2005-10-28 | 2013-11-22 | Device for the implantation and fixation of prosthetic valves |
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US14/454,285 Active 2027-05-31 USRE45790E1 (en) | 2005-10-28 | 2014-08-07 | Device for the implantation and fixation of prosthetic valves |
US14/708,892 Active US9402717B2 (en) | 2005-10-28 | 2015-05-11 | Device for the implantation and fixation of prosthetic valves |
US15/195,625 Active US9855142B2 (en) | 2005-10-28 | 2016-06-28 | Device for the implantation and fixation of prosthetic valves |
US15/821,012 Active US10363134B2 (en) | 2005-10-28 | 2017-11-22 | Device for the implantation and fixation of prosthetic valves |
US16/442,793 Active 2027-10-10 US11116628B2 (en) | 2005-10-28 | 2019-06-17 | Device for the implantation and fixation of prosthetic valves |
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Families Citing this family (247)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6006134A (en) | 1998-04-30 | 1999-12-21 | Medtronic, Inc. | Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers |
US8016877B2 (en) | 1999-11-17 | 2011-09-13 | Medtronic Corevalve Llc | Prosthetic valve for transluminal delivery |
US8579966B2 (en) | 1999-11-17 | 2013-11-12 | Medtronic Corevalve Llc | Prosthetic valve for transluminal delivery |
US7018406B2 (en) | 1999-11-17 | 2006-03-28 | Corevalve Sa | Prosthetic valve for transluminal delivery |
US7749245B2 (en) | 2000-01-27 | 2010-07-06 | Medtronic, Inc. | Cardiac valve procedure methods and devices |
DE10010074B4 (en) | 2000-02-28 | 2005-04-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Device for fastening and anchoring heart valve prostheses |
DE10010073B4 (en) | 2000-02-28 | 2005-12-22 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anchoring for implantable heart valve prostheses |
US8366769B2 (en) | 2000-06-01 | 2013-02-05 | Edwards Lifesciences Corporation | Low-profile, pivotable heart valve sewing ring |
WO2002005888A1 (en) | 2000-06-30 | 2002-01-24 | Viacor Incorporated | Intravascular filter with debris entrapment mechanism |
US6409758B2 (en) | 2000-07-27 | 2002-06-25 | Edwards Lifesciences Corporation | Heart valve holder for constricting the valve commissures and methods of use |
US8623077B2 (en) | 2001-06-29 | 2014-01-07 | Medtronic, Inc. | Apparatus for replacing a cardiac valve |
US7544206B2 (en) | 2001-06-29 | 2009-06-09 | Medtronic, Inc. | Method and apparatus for resecting and replacing an aortic valve |
US8771302B2 (en) | 2001-06-29 | 2014-07-08 | Medtronic, Inc. | Method and apparatus for resecting and replacing an aortic valve |
FR2826863B1 (en) | 2001-07-04 | 2003-09-26 | Jacques Seguin | ASSEMBLY FOR PLACING A PROSTHETIC VALVE IN A BODY CONDUIT |
FR2828091B1 (en) | 2001-07-31 | 2003-11-21 | Seguin Jacques | ASSEMBLY ALLOWING THE PLACEMENT OF A PROTHETIC VALVE IN A BODY DUCT |
FR2828263B1 (en) | 2001-08-03 | 2007-05-11 | Philipp Bonhoeffer | DEVICE FOR IMPLANTATION OF AN IMPLANT AND METHOD FOR IMPLANTATION OF THE DEVICE |
US7097659B2 (en) | 2001-09-07 | 2006-08-29 | Medtronic, Inc. | Fixation band for affixing a prosthetic heart valve to tissue |
US7201771B2 (en) | 2001-12-27 | 2007-04-10 | Arbor Surgical Technologies, Inc. | Bioprosthetic heart valve |
US7959674B2 (en) | 2002-07-16 | 2011-06-14 | Medtronic, Inc. | Suture locking assembly and method of use |
US8551162B2 (en) | 2002-12-20 | 2013-10-08 | Medtronic, Inc. | Biologically implantable prosthesis |
US7201772B2 (en) * | 2003-07-08 | 2007-04-10 | Ventor Technologies, Ltd. | Fluid flow prosthetic device |
US8021421B2 (en) | 2003-08-22 | 2011-09-20 | Medtronic, Inc. | Prosthesis heart valve fixturing device |
US9579194B2 (en) | 2003-10-06 | 2017-02-28 | Medtronic ATS Medical, Inc. | Anchoring structure with concave landing zone |
US7556647B2 (en) | 2003-10-08 | 2009-07-07 | Arbor Surgical Technologies, Inc. | Attachment device and methods of using the same |
US7871435B2 (en) | 2004-01-23 | 2011-01-18 | Edwards Lifesciences Corporation | Anatomically approximate prosthetic mitral heart valve |
ITTO20040135A1 (en) | 2004-03-03 | 2004-06-03 | Sorin Biomedica Cardio Spa | CARDIAC VALVE PROSTHESIS |
CN101052359A (en) | 2004-04-23 | 2007-10-10 | 3F医疗有限公司 | Implantable prosthetic valve |
DE102005003632A1 (en) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Catheter for the transvascular implantation of heart valve prostheses |
ITTO20050074A1 (en) * | 2005-02-10 | 2006-08-11 | Sorin Biomedica Cardio Srl | CARDIAC VALVE PROSTHESIS |
US8574257B2 (en) | 2005-02-10 | 2013-11-05 | Edwards Lifesciences Corporation | System, device, and method for providing access in a cardiovascular environment |
US7513909B2 (en) | 2005-04-08 | 2009-04-07 | Arbor Surgical Technologies, Inc. | Two-piece prosthetic valves with snap-in connection and methods for use |
US7914569B2 (en) | 2005-05-13 | 2011-03-29 | Medtronics Corevalve Llc | Heart valve prosthesis and methods of manufacture and use |
EP2901967B1 (en) | 2005-05-24 | 2019-10-02 | Edwards Lifesciences Corporation | Rapid deployment prosthetic heart valve |
WO2006130505A2 (en) | 2005-05-27 | 2006-12-07 | Arbor Surgical Technologies, Inc. | Gasket with collar for prosthetic heart valves and methods for using them |
US7776084B2 (en) | 2005-07-13 | 2010-08-17 | Edwards Lifesciences Corporation | Prosthetic mitral heart valve having a contoured sewing ring |
US20070078510A1 (en) | 2005-09-26 | 2007-04-05 | Ryan Timothy R | Prosthetic cardiac and venous valves |
DE102005051849B4 (en) | 2005-10-28 | 2010-01-21 | JenaValve Technology Inc., Wilmington | Device for implantation and attachment of heart valve prostheses |
DE102005052628B4 (en) | 2005-11-04 | 2014-06-05 | Jenavalve Technology Inc. | Self-expanding, flexible wire mesh with integrated valvular prosthesis for the transvascular heart valve replacement and a system with such a device and a delivery catheter |
US20070213813A1 (en) | 2005-12-22 | 2007-09-13 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
US7967857B2 (en) | 2006-01-27 | 2011-06-28 | Medtronic, Inc. | Gasket with spring collar for prosthetic heart valves and methods for making and using them |
US8075615B2 (en) | 2006-03-28 | 2011-12-13 | Medtronic, Inc. | Prosthetic cardiac valve formed from pericardium material and methods of making same |
WO2007130881A2 (en) | 2006-04-29 | 2007-11-15 | Arbor Surgical Technologies, Inc. | Multiple component prosthetic heart valve assemblies and apparatus and methods for delivering them |
US8021161B2 (en) | 2006-05-01 | 2011-09-20 | Edwards Lifesciences Corporation | Simulated heart valve root for training and testing |
GB0617219D0 (en) * | 2006-08-31 | 2006-10-11 | Barts & London Nhs Trust | Blood vessel prosthesis and delivery apparatus |
US8414643B2 (en) | 2006-09-19 | 2013-04-09 | Medtronic Ventor Technologies Ltd. | Sinus-engaging valve fixation member |
US8834564B2 (en) | 2006-09-19 | 2014-09-16 | Medtronic, Inc. | Sinus-engaging valve fixation member |
US11304800B2 (en) | 2006-09-19 | 2022-04-19 | Medtronic Ventor Technologies Ltd. | Sinus-engaging valve fixation member |
EP2083901B1 (en) | 2006-10-16 | 2017-12-27 | Medtronic Ventor Technologies Ltd. | Transapical delivery system with ventriculo-arterial overflow bypass |
JP5593545B2 (en) | 2006-12-06 | 2014-09-24 | メドトロニック シーブイ ルクセンブルク エス.アー.エール.エル. | System and method for transapical delivery of a self-expanding valve secured to an annulus |
EP1935378B1 (en) * | 2006-12-19 | 2014-09-17 | Sorin Group Italia S.r.l. | Instrument for in situ positioning of cardiac valve prostheses |
US8070799B2 (en) * | 2006-12-19 | 2011-12-06 | Sorin Biomedica Cardio S.R.L. | Instrument and method for in situ deployment of cardiac valve prostheses |
WO2008103295A2 (en) * | 2007-02-16 | 2008-08-28 | Medtronic, Inc. | Replacement prosthetic heart valves and methods of implantation |
US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US9138315B2 (en) | 2007-04-13 | 2015-09-22 | Jenavalve Technology Gmbh | Medical device for treating a heart valve insufficiency or stenosis |
FR2915087B1 (en) | 2007-04-20 | 2021-11-26 | Corevalve Inc | IMPLANT FOR TREATMENT OF A HEART VALVE, IN PARTICULAR OF A MITRAL VALVE, EQUIPMENT INCLUDING THIS IMPLANT AND MATERIAL FOR PLACING THIS IMPLANT. |
EP2150210B1 (en) | 2007-05-15 | 2016-10-12 | JenaValve Technology, Inc. | Handle for manipulating a catheter tip, catheter system and medical insertion system for inserting a self-expandable heart valve stent |
US8747458B2 (en) | 2007-08-20 | 2014-06-10 | Medtronic Ventor Technologies Ltd. | Stent loading tool and method for use thereof |
US8808367B2 (en) * | 2007-09-07 | 2014-08-19 | Sorin Group Italia S.R.L. | Prosthetic valve delivery system including retrograde/antegrade approach |
US8114154B2 (en) | 2007-09-07 | 2012-02-14 | Sorin Biomedica Cardio S.R.L. | Fluid-filled delivery system for in situ deployment of cardiac valve prostheses |
US10856970B2 (en) | 2007-10-10 | 2020-12-08 | Medtronic Ventor Technologies Ltd. | Prosthetic heart valve for transfemoral delivery |
US9848981B2 (en) * | 2007-10-12 | 2017-12-26 | Mayo Foundation For Medical Education And Research | Expandable valve prosthesis with sealing mechanism |
US7981151B2 (en) * | 2007-10-15 | 2011-07-19 | Edwards Lifesciences Corporation | Transcatheter heart valve with micro-anchors |
US8715337B2 (en) * | 2007-11-09 | 2014-05-06 | Cook Medical Technologies Llc | Aortic valve stent graft |
EP2254512B1 (en) | 2008-01-24 | 2016-01-06 | Medtronic, Inc. | Markers for prosthetic heart valves |
US8157852B2 (en) | 2008-01-24 | 2012-04-17 | Medtronic, Inc. | Delivery systems and methods of implantation for prosthetic heart valves |
US9149358B2 (en) * | 2008-01-24 | 2015-10-06 | Medtronic, Inc. | Delivery systems for prosthetic heart valves |
US9393115B2 (en) | 2008-01-24 | 2016-07-19 | Medtronic, Inc. | Delivery systems and methods of implantation for prosthetic heart valves |
JP5687070B2 (en) | 2008-01-24 | 2015-03-18 | メドトロニック,インコーポレイテッド | Stent for prosthetic heart valve |
WO2009094197A1 (en) | 2008-01-24 | 2009-07-30 | Medtronic, Inc. | Stents for prosthetic heart valves |
WO2009092782A1 (en) | 2008-01-25 | 2009-07-30 | Jenavalve Technology Inc. | Medical apparatus for the therapeutic treatment of an insufficient cardiac valve |
GB0803302D0 (en) * | 2008-02-22 | 2008-04-02 | Barts & London Nhs Trust | Blood vessel prosthesis and delivery apparatus |
WO2011104269A1 (en) | 2008-02-26 | 2011-09-01 | Jenavalve Technology Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
US8465540B2 (en) | 2008-02-26 | 2013-06-18 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis |
US8398704B2 (en) | 2008-02-26 | 2013-03-19 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US9168130B2 (en) | 2008-02-26 | 2015-10-27 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US8317858B2 (en) | 2008-02-26 | 2012-11-27 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
WO2009108355A1 (en) | 2008-02-28 | 2009-09-03 | Medtronic, Inc. | Prosthetic heart valve systems |
US8313525B2 (en) * | 2008-03-18 | 2012-11-20 | Medtronic Ventor Technologies, Ltd. | Valve suturing and implantation procedures |
US8430927B2 (en) | 2008-04-08 | 2013-04-30 | Medtronic, Inc. | Multiple orifice implantable heart valve and methods of implantation |
US8696743B2 (en) | 2008-04-23 | 2014-04-15 | Medtronic, Inc. | Tissue attachment devices and methods for prosthetic heart valves |
US8312825B2 (en) | 2008-04-23 | 2012-11-20 | Medtronic, Inc. | Methods and apparatuses for assembly of a pericardial prosthetic heart valve |
EP2119417B2 (en) | 2008-05-16 | 2020-04-29 | Sorin Group Italia S.r.l. | Atraumatic prosthetic heart valve prosthesis |
US8323335B2 (en) | 2008-06-20 | 2012-12-04 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves and methods for using |
EP2358307B1 (en) | 2008-09-15 | 2021-12-15 | Medtronic Ventor Technologies Ltd. | Prosthetic heart valve having identifiers for aiding in radiographic positioning |
US8721714B2 (en) | 2008-09-17 | 2014-05-13 | Medtronic Corevalve Llc | Delivery system for deployment of medical devices |
EP2367505B1 (en) | 2008-09-29 | 2020-08-12 | Edwards Lifesciences CardiAQ LLC | Heart valve |
CA2739275C (en) | 2008-10-01 | 2017-01-17 | Impala, Inc. | Delivery system for vascular implant |
US8690936B2 (en) | 2008-10-10 | 2014-04-08 | Edwards Lifesciences Corporation | Expandable sheath for introducing an endovascular delivery device into a body |
US8137398B2 (en) | 2008-10-13 | 2012-03-20 | Medtronic Ventor Technologies Ltd | Prosthetic valve having tapered tip when compressed for delivery |
US8449625B2 (en) | 2009-10-27 | 2013-05-28 | Edwards Lifesciences Corporation | Methods of measuring heart valve annuluses for valve replacement |
US8986361B2 (en) | 2008-10-17 | 2015-03-24 | Medtronic Corevalve, Inc. | Delivery system for deployment of medical devices |
CA2743719C (en) | 2008-11-25 | 2019-03-19 | Edwards Lifesciences Corporation | Apparatus and method for in situ expansion of prosthetic device |
US8308798B2 (en) | 2008-12-19 | 2012-11-13 | Edwards Lifesciences Corporation | Quick-connect prosthetic heart valve and methods |
EP2201911B1 (en) | 2008-12-23 | 2015-09-30 | Sorin Group Italia S.r.l. | Expandable prosthetic valve having anchoring appendages |
WO2010117680A1 (en) | 2009-03-30 | 2010-10-14 | Cardiovantage Medical, Inc. | Sutureless valve prostheses and devices and methods for delivery |
US9980818B2 (en) | 2009-03-31 | 2018-05-29 | Edwards Lifesciences Corporation | Prosthetic heart valve system with positioning markers |
CA2961053C (en) | 2009-04-15 | 2019-04-30 | Edwards Lifesciences Cardiaq Llc | Vascular implant and delivery system |
US8512397B2 (en) | 2009-04-27 | 2013-08-20 | Sorin Group Italia S.R.L. | Prosthetic vascular conduit |
US8353953B2 (en) | 2009-05-13 | 2013-01-15 | Sorin Biomedica Cardio, S.R.L. | Device for the in situ delivery of heart valves |
US9168105B2 (en) | 2009-05-13 | 2015-10-27 | Sorin Group Italia S.R.L. | Device for surgical interventions |
US8403982B2 (en) * | 2009-05-13 | 2013-03-26 | Sorin Group Italia S.R.L. | Device for the in situ delivery of heart valves |
US8468667B2 (en) | 2009-05-15 | 2013-06-25 | Jenavalve Technology, Inc. | Device for compressing a stent |
US8348998B2 (en) | 2009-06-26 | 2013-01-08 | Edwards Lifesciences Corporation | Unitary quick connect prosthetic heart valve and deployment system and methods |
US8808369B2 (en) | 2009-10-05 | 2014-08-19 | Mayo Foundation For Medical Education And Research | Minimally invasive aortic valve replacement |
US8449599B2 (en) * | 2009-12-04 | 2013-05-28 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US8870950B2 (en) | 2009-12-08 | 2014-10-28 | Mitral Tech Ltd. | Rotation-based anchoring of an implant |
CN102113921A (en) * | 2009-12-30 | 2011-07-06 | 微创医疗器械(上海)有限公司 | Intervention-type heart valve |
US9226826B2 (en) | 2010-02-24 | 2016-01-05 | Medtronic, Inc. | Transcatheter valve structure and methods for valve delivery |
WO2011111047A2 (en) | 2010-03-10 | 2011-09-15 | Mitraltech Ltd. | Prosthetic mitral valve with tissue anchors |
US8652204B2 (en) | 2010-04-01 | 2014-02-18 | Medtronic, Inc. | Transcatheter valve with torsion spring fixation and related systems and methods |
US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
CN102883684B (en) | 2010-05-10 | 2015-04-08 | 爱德华兹生命科学公司 | Prosthetic heart valve |
US9554901B2 (en) | 2010-05-12 | 2017-01-31 | Edwards Lifesciences Corporation | Low gradient prosthetic heart valve |
US11278406B2 (en) | 2010-05-20 | 2022-03-22 | Jenavalve Technology, Inc. | Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect |
US10856978B2 (en) | 2010-05-20 | 2020-12-08 | Jenavalve Technology, Inc. | Catheter system |
IT1400327B1 (en) | 2010-05-21 | 2013-05-24 | Sorin Biomedica Cardio Srl | SUPPORT DEVICE FOR VALVULAR PROSTHESIS AND CORRESPONDING CORRESPONDENT. |
JP2013526388A (en) | 2010-05-25 | 2013-06-24 | イエナバルブ テクノロジー インク | Artificial heart valve, and transcatheter delivery prosthesis comprising an artificial heart valve and a stent |
EP2579809B1 (en) | 2010-06-08 | 2020-11-25 | Regents of the University of Minnesota | Vascular elastance |
US9763657B2 (en) | 2010-07-21 | 2017-09-19 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US8992604B2 (en) | 2010-07-21 | 2015-03-31 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US11653910B2 (en) | 2010-07-21 | 2023-05-23 | Cardiovalve Ltd. | Helical anchor implantation |
US9132009B2 (en) | 2010-07-21 | 2015-09-15 | Mitraltech Ltd. | Guide wires with commissural anchors to advance a prosthetic valve |
US9918833B2 (en) | 2010-09-01 | 2018-03-20 | Medtronic Vascular Galway | Prosthetic valve support structure |
US9125741B2 (en) | 2010-09-10 | 2015-09-08 | Edwards Lifesciences Corporation | Systems and methods for ensuring safe and rapid deployment of prosthetic heart valves |
US8641757B2 (en) | 2010-09-10 | 2014-02-04 | Edwards Lifesciences Corporation | Systems for rapidly deploying surgical heart valves |
US9370418B2 (en) | 2010-09-10 | 2016-06-21 | Edwards Lifesciences Corporation | Rapidly deployable surgical heart valves |
US8845720B2 (en) | 2010-09-27 | 2014-09-30 | Edwards Lifesciences Corporation | Prosthetic heart valve frame with flexible commissures |
US20120116496A1 (en) | 2010-11-05 | 2012-05-10 | Chuter Timothy A | Stent structures for use with valve replacements |
WO2012071395A1 (en) | 2010-11-22 | 2012-05-31 | Aria Cv, Inc. | System and method for reducing pulsatile pressure |
EP2663258B1 (en) | 2011-01-11 | 2018-11-21 | Hans Reiner Figulla | Prosthetic valve for replacing an atrioventricular heart valve |
EP2663257B1 (en) | 2011-01-11 | 2016-10-26 | Hans Reiner Figulla | Valve prosthesis for replacing an atrioventricular valve of the heart |
EP2486893B1 (en) | 2011-02-14 | 2017-07-05 | Sorin Group Italia S.r.l. | Sutureless anchoring device for cardiac valve prostheses |
EP2486894B1 (en) | 2011-02-14 | 2021-06-09 | Sorin Group Italia S.r.l. | Sutureless anchoring device for cardiac valve prostheses |
EP2688516B1 (en) | 2011-03-21 | 2022-08-17 | Cephea Valve Technologies, Inc. | Disk-based valve apparatus |
US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US8945209B2 (en) | 2011-05-20 | 2015-02-03 | Edwards Lifesciences Corporation | Encapsulated heart valve |
US20120303048A1 (en) | 2011-05-24 | 2012-11-29 | Sorin Biomedica Cardio S.R.I. | Transapical valve replacement |
US20140324164A1 (en) | 2011-08-05 | 2014-10-30 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
WO2013021375A2 (en) | 2011-08-05 | 2013-02-14 | Mitraltech Ltd. | Percutaneous mitral valve replacement and sealing |
US8852272B2 (en) | 2011-08-05 | 2014-10-07 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
WO2013021374A2 (en) | 2011-08-05 | 2013-02-14 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
EP2768432A1 (en) | 2011-10-21 | 2014-08-27 | JenaValve Technology Inc. | Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect |
US9078747B2 (en) | 2011-12-21 | 2015-07-14 | Edwards Lifesciences Corporation | Anchoring device for replacing or repairing a heart valve |
EP2609893B1 (en) | 2011-12-29 | 2014-09-03 | Sorin Group Italia S.r.l. | A kit for implanting prosthetic vascular conduits |
EP2620125B1 (en) | 2012-01-24 | 2017-10-11 | Medtentia International Ltd Oy | An arrangement, a loop-shaped support, a prosthetic heart valve and a method of repairing or replacing a native heart valve |
US9427315B2 (en) | 2012-04-19 | 2016-08-30 | Caisson Interventional, LLC | Valve replacement systems and methods |
US9011515B2 (en) | 2012-04-19 | 2015-04-21 | Caisson Interventional, LLC | Heart valve assembly systems and methods |
US9878127B2 (en) | 2012-05-16 | 2018-01-30 | Jenavalve Technology, Inc. | Catheter delivery system for heart valve prosthesis |
US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US9510946B2 (en) | 2012-09-06 | 2016-12-06 | Edwards Lifesciences Corporation | Heart valve sealing devices |
EP2742911A1 (en) | 2012-12-17 | 2014-06-18 | Hans Reiner Figulla | Valve prosthesis for replacing an atrioventricular valve |
EP2948103B1 (en) | 2013-01-24 | 2022-12-07 | Cardiovalve Ltd | Ventricularly-anchored prosthetic valves |
US9439763B2 (en) | 2013-02-04 | 2016-09-13 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US10583002B2 (en) | 2013-03-11 | 2020-03-10 | Neovasc Tiara Inc. | Prosthetic valve with anti-pivoting mechanism |
CN105263443B (en) | 2013-03-14 | 2017-11-14 | 心肺医疗股份有限公司 | Sutureless valve prosthesis delivery apparatus and its application method |
US9681951B2 (en) | 2013-03-14 | 2017-06-20 | Edwards Lifesciences Cardiaq Llc | Prosthesis with outer skirt and anchors |
US11007058B2 (en) | 2013-03-15 | 2021-05-18 | Edwards Lifesciences Corporation | Valved aortic conduits |
SG11201506352SA (en) | 2013-03-15 | 2015-09-29 | Edwards Lifesciences Corp | Valved aortic conduits |
US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
EP2991586A1 (en) | 2013-05-03 | 2016-03-09 | Medtronic Inc. | Valve delivery tool |
US9468527B2 (en) | 2013-06-12 | 2016-10-18 | Edwards Lifesciences Corporation | Cardiac implant with integrated suture fasteners |
US8870948B1 (en) | 2013-07-17 | 2014-10-28 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US9919137B2 (en) | 2013-08-28 | 2018-03-20 | Edwards Lifesciences Corporation | Integrated balloon catheter inflation system |
CN105491978A (en) | 2013-08-30 | 2016-04-13 | 耶拿阀门科技股份有限公司 | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
SG11201508895RA (en) | 2013-09-20 | 2015-11-27 | Edwards Lifesciences Corp | Heart valves with increased effective orifice area |
US9421094B2 (en) | 2013-10-23 | 2016-08-23 | Caisson Interventional, LLC | Methods and systems for heart valve therapy |
US20150122687A1 (en) | 2013-11-06 | 2015-05-07 | Edwards Lifesciences Corporation | Bioprosthetic heart valves having adaptive seals to minimize paravalvular leakage |
US9549816B2 (en) | 2014-04-03 | 2017-01-24 | Edwards Lifesciences Corporation | Method for manufacturing high durability heart valve |
US9585752B2 (en) | 2014-04-30 | 2017-03-07 | Edwards Lifesciences Corporation | Holder and deployment system for surgical heart valves |
US9532870B2 (en) | 2014-06-06 | 2017-01-03 | Edwards Lifesciences Corporation | Prosthetic valve for replacing a mitral valve |
US9974647B2 (en) | 2014-06-12 | 2018-05-22 | Caisson Interventional, LLC | Two stage anchor and mitral valve assembly |
US8876850B1 (en) | 2014-06-19 | 2014-11-04 | Aria Cv, Inc. | Systems and methods for treating pulmonary hypertension |
USD867594S1 (en) | 2015-06-19 | 2019-11-19 | Edwards Lifesciences Corporation | Prosthetic heart valve |
CA2914094C (en) | 2014-06-20 | 2021-01-05 | Edwards Lifesciences Corporation | Surgical heart valves identifiable post-implant |
US10195026B2 (en) | 2014-07-22 | 2019-02-05 | Edwards Lifesciences Corporation | Mitral valve anchoring |
EP4066786A1 (en) | 2014-07-30 | 2022-10-05 | Cardiovalve Ltd. | Articulatable prosthetic valve |
US10058424B2 (en) | 2014-08-21 | 2018-08-28 | Edwards Lifesciences Corporation | Dual-flange prosthetic valve frame |
US10016272B2 (en) | 2014-09-12 | 2018-07-10 | Mitral Valve Technologies Sarl | Mitral repair and replacement devices and methods |
US9750605B2 (en) | 2014-10-23 | 2017-09-05 | Caisson Interventional, LLC | Systems and methods for heart valve therapy |
US9750607B2 (en) | 2014-10-23 | 2017-09-05 | Caisson Interventional, LLC | Systems and methods for heart valve therapy |
US9439757B2 (en) | 2014-12-09 | 2016-09-13 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
EP3253333B1 (en) | 2015-02-05 | 2024-04-03 | Cardiovalve Ltd | Prosthetic valve with axially-sliding frames |
US9974651B2 (en) | 2015-02-05 | 2018-05-22 | Mitral Tech Ltd. | Prosthetic valve with axially-sliding frames |
CN107613908B (en) | 2015-03-19 | 2020-03-10 | 凯森因特万逊奈尔有限公司 | Systems and methods for heart valve therapy |
US20180116843A1 (en) | 2015-03-20 | 2018-05-03 | Jenavalve Technology, Inc. | Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath |
US10064718B2 (en) | 2015-04-16 | 2018-09-04 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US10010417B2 (en) | 2015-04-16 | 2018-07-03 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US10610249B2 (en) | 2015-04-30 | 2020-04-07 | Septulus Ab | Tissue cutting device and system |
US10709555B2 (en) | 2015-05-01 | 2020-07-14 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
EP3294220B1 (en) | 2015-05-14 | 2023-12-06 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
WO2016183526A1 (en) | 2015-05-14 | 2016-11-17 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
WO2017004369A1 (en) | 2015-07-02 | 2017-01-05 | Edwards Lifesciences Corporation | Hybrid heart valves adapted for post-implant expansion |
CR20170597A (en) | 2015-07-02 | 2018-04-20 | Edwards Lifesciences Corp | INTEGRATED HYBRID HEART VALVES |
US10034747B2 (en) | 2015-08-27 | 2018-07-31 | Medtronic Vascular, Inc. | Prosthetic valve system having a docking component and a prosthetic valve component |
EP3344158B1 (en) | 2015-09-02 | 2023-03-01 | Edwards Lifesciences Corporation | Spacer for securing a transcatheter valve to a bioprosthetic cardiac structure |
US10080653B2 (en) | 2015-09-10 | 2018-09-25 | Edwards Lifesciences Corporation | Limited expansion heart valve |
US10470876B2 (en) | 2015-11-10 | 2019-11-12 | Edwards Lifesciences Corporation | Transcatheter heart valve for replacing natural mitral valve |
US10376364B2 (en) | 2015-11-10 | 2019-08-13 | Edwards Lifesciences Corporation | Implant delivery capsule |
EP3960127A1 (en) | 2015-12-30 | 2022-03-02 | Caisson Interventional, LLC | Systems and methods for heart valve therapy |
US10433952B2 (en) | 2016-01-29 | 2019-10-08 | Neovasc Tiara Inc. | Prosthetic valve for avoiding obstruction of outflow |
CN107019581B (en) * | 2016-02-02 | 2021-07-16 | 中国人民解放军第二军医大学 | Ascending aorta and aortic valve integrated intravascular stent |
US10531866B2 (en) | 2016-02-16 | 2020-01-14 | Cardiovalve Ltd. | Techniques for providing a replacement valve and transseptal communication |
US10667904B2 (en) | 2016-03-08 | 2020-06-02 | Edwards Lifesciences Corporation | Valve implant with integrated sensor and transmitter |
EP3454795B1 (en) | 2016-05-13 | 2023-01-11 | JenaValve Technology, Inc. | Heart valve prosthesis delivery system for delivery of heart valve prosthesis with introducer sheath and loading system |
US10456245B2 (en) | 2016-05-16 | 2019-10-29 | Edwards Lifesciences Corporation | System and method for applying material to a stent |
US11331187B2 (en) | 2016-06-17 | 2022-05-17 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
US10588745B2 (en) | 2016-06-20 | 2020-03-17 | Medtronic Vascular, Inc. | Modular valve prosthesis, delivery system, and method of delivering and deploying a modular valve prosthesis |
USD800908S1 (en) | 2016-08-10 | 2017-10-24 | Mitraltech Ltd. | Prosthetic valve element |
CN114587712A (en) | 2016-08-10 | 2022-06-07 | 卡迪尔维尔福股份有限公司 | Prosthetic valve with coaxial frame |
US11331105B2 (en) | 2016-10-19 | 2022-05-17 | Aria Cv, Inc. | Diffusion resistant implantable devices for reducing pulsatile pressure |
AU2017361296B2 (en) | 2016-11-21 | 2022-09-29 | Neovasc Tiara Inc. | Methods and systems for rapid retraction of a transcatheter heart valve delivery system |
USD846122S1 (en) | 2016-12-16 | 2019-04-16 | Edwards Lifesciences Corporation | Heart valve sizer |
CR20190381A (en) | 2017-01-23 | 2019-09-27 | Cephea Valve Tech Inc | Replacement mitral valves |
AU2018203053B2 (en) | 2017-01-23 | 2020-03-05 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10561495B2 (en) | 2017-01-24 | 2020-02-18 | 4C Medical Technologies, Inc. | Systems, methods and devices for two-step delivery and implantation of prosthetic heart valve |
CN110392557A (en) | 2017-01-27 | 2019-10-29 | 耶拿阀门科技股份有限公司 | Heart valve simulation |
IT201700031905A1 (en) * | 2017-03-23 | 2018-09-23 | Enrico Riccardo Ferrari | Aortic endoprosthesis. |
US10463485B2 (en) | 2017-04-06 | 2019-11-05 | Edwards Lifesciences Corporation | Prosthetic valve holders with automatic deploying mechanisms |
CA3060663C (en) | 2017-04-28 | 2024-03-26 | Edwards Lifesciences Corporation | Prosthetic heart valve with collapsible holder |
CN110831547B (en) | 2017-06-21 | 2022-07-15 | 爱德华兹生命科学公司 | Double-wire limited expansion heart valve |
US10537426B2 (en) | 2017-08-03 | 2020-01-21 | Cardiovalve Ltd. | Prosthetic heart valve |
US11793633B2 (en) | 2017-08-03 | 2023-10-24 | Cardiovalve Ltd. | Prosthetic heart valve |
US10575948B2 (en) | 2017-08-03 | 2020-03-03 | Cardiovalve Ltd. | Prosthetic heart valve |
US11246704B2 (en) | 2017-08-03 | 2022-02-15 | Cardiovalve Ltd. | Prosthetic heart valve |
US10888421B2 (en) | 2017-09-19 | 2021-01-12 | Cardiovalve Ltd. | Prosthetic heart valve with pouch |
US10856984B2 (en) | 2017-08-25 | 2020-12-08 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
GB201720803D0 (en) | 2017-12-13 | 2018-01-24 | Mitraltech Ltd | Prosthetic Valve and delivery tool therefor |
CN117796968A (en) | 2018-01-07 | 2024-04-02 | 苏州杰成医疗科技有限公司 | valve prosthesis |
GB201800399D0 (en) | 2018-01-10 | 2018-02-21 | Mitraltech Ltd | Temperature-control during crimping of an implant |
CN111565678B (en) | 2018-01-23 | 2023-07-07 | 爱德华兹生命科学公司 | Prosthetic valve holders, systems, and methods |
AU2018424859B2 (en) | 2018-05-23 | 2024-04-04 | Corcym S.R.L. | A cardiac valve prosthesis |
US10441449B1 (en) | 2018-05-30 | 2019-10-15 | Vesper Medical, Inc. | Rotary handle stent delivery system and method |
USD908874S1 (en) | 2018-07-11 | 2021-01-26 | Edwards Lifesciences Corporation | Collapsible heart valve sizer |
US11857441B2 (en) | 2018-09-04 | 2024-01-02 | 4C Medical Technologies, Inc. | Stent loading device |
US10449073B1 (en) | 2018-09-18 | 2019-10-22 | Vesper Medical, Inc. | Rotary handle stent delivery system and method |
CA3118599A1 (en) | 2018-11-08 | 2020-05-14 | Neovasc Tiara Inc. | Ventricular deployment of a transcatheter mitral valve prosthesis |
US11602429B2 (en) | 2019-04-01 | 2023-03-14 | Neovasc Tiara Inc. | Controllably deployable prosthetic valve |
AU2020271896B2 (en) | 2019-04-10 | 2022-10-13 | Neovasc Tiara Inc. | Prosthetic valve with natural blood flow |
EP3972673A4 (en) | 2019-05-20 | 2023-06-07 | Neovasc Tiara Inc. | Introducer with hemostasis mechanism |
WO2020257643A1 (en) | 2019-06-20 | 2020-12-24 | Neovasc Tiara Inc. | Low profile prosthetic mitral valve |
EP4025287A1 (en) | 2019-09-06 | 2022-07-13 | Aria CV, Inc. | Diffusion and infusion resistant implantable devices for reducing pulsatile pressure |
WO2021126778A1 (en) | 2019-12-16 | 2021-06-24 | Edwards Lifesciences Corporation | Valve holder assembly with suture looping protection |
US11931253B2 (en) | 2020-01-31 | 2024-03-19 | 4C Medical Technologies, Inc. | Prosthetic heart valve delivery system: ball-slide attachment |
US11219541B2 (en) | 2020-05-21 | 2022-01-11 | Vesper Medical, Inc. | Wheel lock for thumbwheel actuated device |
US11707355B2 (en) | 2020-05-28 | 2023-07-25 | Medtronic, Inc. | Modular heart valve prosthesis |
Citations (229)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0084395A1 (en) | 1982-01-20 | 1983-07-27 | Martin Morris Black | Artificial heart valves |
US4922905A (en) | 1985-11-30 | 1990-05-08 | Strecker Ernst P | Dilatation catheter |
WO1990009102A1 (en) | 1989-02-17 | 1990-08-23 | Baxter International Inc. | Calcification mitigation of bioprosthetic implants |
US5002566A (en) | 1989-02-17 | 1991-03-26 | Baxter International Inc. | Calcification mitigation of bioprosthetic implants |
US5061277A (en) | 1986-08-06 | 1991-10-29 | Baxter International Inc. | Flexible cardiac valvular support prosthesis |
US5094661A (en) | 1988-04-01 | 1992-03-10 | The University Of Michigan | Calcification-resistant materials and methods of making same through use of trivalent aluminum |
US5104407A (en) | 1989-02-13 | 1992-04-14 | Baxter International Inc. | Selectively flexible annuloplasty ring |
EP0515324A1 (en) | 1991-05-24 | 1992-11-25 | SORIN BIOMEDICA CARDIO S.p.A. | A cardiac valve prosthesis, particularly for replacement of the aortic valve |
US5197979A (en) | 1990-09-07 | 1993-03-30 | Baxter International Inc. | Stentless heart valve and holder |
US5279612A (en) | 1989-06-09 | 1994-01-18 | Medtronic, Inc. | Dynamic fixation of porcine aortic valves |
US5332402A (en) | 1992-05-12 | 1994-07-26 | Teitelbaum George P | Percutaneously-inserted cardiac valve |
US5352240A (en) | 1989-05-31 | 1994-10-04 | Promedica International, Inc. | Human heart valve replacement with porcine pulmonary valve |
US5368608A (en) | 1988-04-01 | 1994-11-29 | University Of Michigan, The Board Of Regents | Calcification-resistant materials and methods of making same through use of multivalent cations |
WO1995011055A1 (en) | 1993-10-22 | 1995-04-27 | Scimed Lifesystems, Inc. | Improved stent delivery apparatus and method |
US5411552A (en) | 1990-05-18 | 1995-05-02 | Andersen; Henning R. | Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis |
WO1995024873A1 (en) | 1994-03-14 | 1995-09-21 | Cryolife, Inc. | Treated tissue for implantation and preparation methods |
US5456713A (en) | 1991-10-25 | 1995-10-10 | Cook Incorporated | Expandable transluminal graft prosthesis for repairs of aneurysm and method for implanting |
EP0592410B1 (en) | 1990-05-18 | 1995-10-11 | ANDERSEN, Henning Rud | A valve prosthesis for implantation in the body and a catheter for implantating such valve prosthesis |
WO1995028183A1 (en) | 1994-04-18 | 1995-10-26 | Hancock Jaffe Laboratories | Biological material pre-fixation treatment |
US5509930A (en) | 1993-12-17 | 1996-04-23 | Autogenics | Stentless heart valve |
WO1996013227A1 (en) | 1994-10-21 | 1996-05-09 | University Of Michigan | Calcification-resistant bioprosthetic tissue and methods of making same |
US5549666A (en) | 1994-09-02 | 1996-08-27 | Baxter International Inc. | Natural tissue valve prostheses having variably complaint leaflets |
DE19546692A1 (en) | 1995-12-14 | 1997-06-19 | Figulla Hans Reiner Prof Dr Me | Self-expandable heart valve bio-prosthesis or synthetic polyurethane valve |
WO1997032615A1 (en) | 1996-03-04 | 1997-09-12 | Baxter International Inc. | Nonpolymeric epoxy compounds for cross-linking biological tissue and bioprosthetic grafts prepared thereby |
US5683451A (en) | 1994-06-08 | 1997-11-04 | Cardiovascular Concepts, Inc. | Apparatus and methods for deployment release of intraluminal prostheses |
US5697972A (en) | 1994-07-13 | 1997-12-16 | Korea Institute Of Science And Technology | Bioprosthetic heart valves having high calcification resistance |
US5746775A (en) | 1988-04-01 | 1998-05-05 | The Board Of Regent6S Of The University Of Michigan | Method of making calcification-resistant bioprosthetic tissue |
US5755777A (en) | 1991-10-25 | 1998-05-26 | Cook Incorporated | Expandable transluminal graft prosthesis for repair of aneurysm |
WO1998043556A1 (en) | 1997-03-27 | 1998-10-08 | Baxter International Inc. | Natural tissue heart valves and methods of making same |
US5824041A (en) | 1994-06-08 | 1998-10-20 | Medtronic, Inc. | Apparatus and methods for placement and repositioning of intraluminal prostheses |
US5824080A (en) | 1995-09-28 | 1998-10-20 | The General Hospital Corporation | Photochemistry for the preparation of biologic grafts--allografts and xenografts |
WO1998046165A1 (en) | 1997-04-11 | 1998-10-22 | Cryolife, Inc. | Tissue decellularization |
US5841382A (en) | 1997-03-19 | 1998-11-24 | Lucent Technologies Inc. | Fast testing of D/A converters |
EP0778775B1 (en) | 1994-09-01 | 1999-01-20 | PHARMACIA & UPJOHN COMPANY | Cosolvent parenteral formulation of tirilazad |
US5876434A (en) | 1997-07-13 | 1999-03-02 | Litana Ltd. | Implantable medical devices of shape memory alloy |
EP0928615A1 (en) | 1996-06-12 | 1999-07-14 | A.S.A. Sangyo CO., Ltd. | Method for recovering and regenerating peritoneal dialyzate, apparatus therefor, and attachments thereof |
US5935163A (en) | 1998-03-31 | 1999-08-10 | Shelhigh, Inc. | Natural tissue heart valve prosthesis |
US5957949A (en) | 1997-05-01 | 1999-09-28 | World Medical Manufacturing Corp. | Percutaneous placement valve stent |
WO1999037337A3 (en) | 1998-01-27 | 1999-09-30 | St Jude Medical | Prostheses with associated growth factors |
US6001126A (en) | 1997-12-24 | 1999-12-14 | Baxter International Inc. | Stentless bioprosthetic heart valve with coronary protuberances and related methods for surgical repair of defective heart valves |
WO2000018445A1 (en) | 1998-09-30 | 2000-04-06 | Medtronic, Inc. | Process for reducing mineralization of tissue used in transplantation |
WO2000025702A1 (en) | 1998-11-03 | 2000-05-11 | Jacques Seguin | Prosthesis for corporeal duct, in particular vascular stent |
DE20003874U1 (en) | 2000-02-28 | 2000-05-25 | Fraunhofer Ges Forschung | Device for fastening and anchoring heart valve prostheses |
US6077297A (en) | 1993-11-04 | 2000-06-20 | C. R. Bard, Inc. | Non-migrating vascular prosthesis and minimally invasive placement system therefor |
DE19857887A1 (en) | 1998-12-15 | 2000-07-06 | Fraunhofer Ges Forschung | Anchoring support for a heart valve prosthesis comprises a single-piece component which is formed of rod shaped elements made of a memory metal, and has at least in part a lattice structure |
US6093530A (en) | 1998-02-06 | 2000-07-25 | Sulzer Carbomedics Inc. | Non-calcific biomaterial by glutaraldehyde followed by oxidative fixation |
WO2000047139A1 (en) | 1999-02-10 | 2000-08-17 | Heartport, Inc. | Methods and devices for implanting cardiac valves |
US6117169A (en) | 1998-06-24 | 2000-09-12 | Sulzer Carbomedics Inc. | Living hinge attachment of leaflet to a valve body |
WO2000053125A1 (en) | 1999-03-10 | 2000-09-14 | Sulzer Carbomedics Inc. | Pre-stressed devices incorporating materials subject to stress softening |
WO2000062714A1 (en) | 1999-04-15 | 2000-10-26 | Sulzer Carbomedics Inc. | Heart valve leaflet with scalloped free margin |
US6177514B1 (en) | 1999-04-09 | 2001-01-23 | Sulzer Carbomedics Inc. | Blocked functional reagants for cross-linking biological tissues |
US6183481B1 (en) | 1999-09-22 | 2001-02-06 | Endomed Inc. | Delivery system for self-expanding stents and grafts |
WO2001010209A1 (en) | 1999-08-11 | 2001-02-15 | Biomedical Design, Inc. | Sterilization of biological tissue |
US6200336B1 (en) | 1998-06-02 | 2001-03-13 | Cook Incorporated | Multiple-sided intraluminal medical device |
WO2000015148A8 (en) | 1998-09-10 | 2001-03-22 | Percardia Inc | Transmyocardial shunt made with a blood vessel graft for left ventricular revascularization |
US6214055B1 (en) | 1998-10-30 | 2001-04-10 | Mures Cardiovascular Research, Inc. | Method and kit for rapid preparation of autologous tissue medical devices |
EP1089676A2 (en) | 1998-06-24 | 2001-04-11 | Sulzer Carbomedics Inc. | Altering heart valve leaflet attachment geometry to influence the location and magnitude of maximum loaded stress on the leaflet |
US6231602B1 (en) | 1999-04-16 | 2001-05-15 | Edwards Lifesciences Corporation | Aortic annuloplasty ring |
WO2001035870A1 (en) | 1999-11-17 | 2001-05-25 | Jacques Seguin | Device for replacing a cardiac valve by percutaneous route |
WO2001041679A1 (en) | 1999-12-08 | 2001-06-14 | Aortech Europe Limited | Hearth valve prosthesis and method of manufacture |
US6254636B1 (en) | 1998-06-26 | 2001-07-03 | St. Jude Medical, Inc. | Single suture biological tissue aortic stentless valve |
WO2001051104A1 (en) | 2000-01-10 | 2001-07-19 | St. Jude Medical, Inc. | Biocompatible prosthetic tissue |
WO2001054625A1 (en) | 2000-01-31 | 2001-08-02 | Cook Biotech Incorporated | Stent valves and uses of same |
WO2001058503A1 (en) | 2000-02-09 | 2001-08-16 | The Children's Hospital Of Philadelphia | Stabilization of implantable bioprosthetic tissue |
WO2001062189A1 (en) | 2000-02-28 | 2001-08-30 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Device for fastening and anchoring cardiac valve prostheses |
WO2001064137A1 (en) | 2000-02-28 | 2001-09-07 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anchoring system for implantable heart valve prostheses |
US20010039450A1 (en) | 1999-06-02 | 2001-11-08 | Dusan Pavcnik | Implantable vascular device |
US6338740B1 (en) | 1999-01-26 | 2002-01-15 | Edwards Lifesciences Corporation | Flexible heart valve leaflets |
US6344044B1 (en) | 2000-02-11 | 2002-02-05 | Edwards Lifesciences Corp. | Apparatus and methods for delivery of intraluminal prosthesis |
US20020032481A1 (en) | 2000-09-12 | 2002-03-14 | Shlomo Gabbay | Heart valve prosthesis and sutureless implantation of a heart valve prosthesis |
US6379740B1 (en) | 1997-12-10 | 2002-04-30 | Sorin Biomedica Cardio S.P.A. | Method for treating a prosthesis having an apertured structure and associated devices |
US20020055775A1 (en) | 1999-01-26 | 2002-05-09 | Alain F. Carpentier | Flexible heart valve |
WO2002036048A1 (en) | 2000-10-31 | 2002-05-10 | Jacques Seguin | Tubular support for setting, by percutaneous route, a substitution cusp |
WO2002058745A1 (en) | 2000-12-06 | 2002-08-01 | Frey, Rainer | Method for conserving biological protheses, conserved biological protheses and conserving solutions |
US20020123790A1 (en) | 1999-09-28 | 2002-09-05 | White Geoffrey Hamilton | Enhanced engagement member for anchoring prosthetic devices in body lumen |
US20020133226A1 (en) | 1999-01-26 | 2002-09-19 | Salvador Marquez | Holder for flexible heart valve |
US6454799B1 (en) | 2000-04-06 | 2002-09-24 | Edwards Lifesciences Corporation | Minimally-invasive heart valves and methods of use |
US6478819B2 (en) | 1999-05-27 | 2002-11-12 | Sulzer Carbomedics Inc. | Prosthetic heart valves with flexible post geometry |
DE10121210A1 (en) | 2001-04-30 | 2002-11-14 | Universitaetsklinikum Freiburg | Replacement heart valve, comprises an anchoring element, and has a starting volume which is opened up to the normal volume using a catheter |
WO2002100301A1 (en) | 2001-06-13 | 2002-12-19 | Aortech Europe Limited | Heat valve prosthesis and method of manufacture |
WO2002102286A1 (en) | 2001-06-14 | 2002-12-27 | Cemvac System Ab | Method and device for preparation of bone cement |
WO2003003949A2 (en) | 2001-07-04 | 2003-01-16 | Jacques Seguin | Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body |
US20030014104A1 (en) | 1996-12-31 | 2003-01-16 | Alain Cribier | Value prosthesis for implantation in body channels |
US20030023300A1 (en) | 1999-12-31 | 2003-01-30 | Bailey Steven R. | Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof |
WO2003007795A2 (en) | 2001-07-16 | 2003-01-30 | Edwards Lifesciences Corporation | Tissue engineered heart valve |
EP1281375A2 (en) | 2001-08-03 | 2003-02-05 | Philipp Bonhoeffer | Implantation device and method for an endoprosthesis |
EP1281357A2 (en) | 1997-09-26 | 2003-02-05 | Duke University | Perfusion-occlusion catheter and methods |
WO2003009785A1 (en) | 2001-07-26 | 2003-02-06 | 3F Therapeutics, Inc. | Method of cutting material for use in implantable medical device |
WO2003011195A2 (en) | 2001-07-31 | 2003-02-13 | Corevalve | Assembly for setting a valve prosthesis in a corporeal duct |
US20030050694A1 (en) | 2001-09-13 | 2003-03-13 | Jibin Yang | Methods and apparatuses for deploying minimally-invasive heart valves |
US20030055495A1 (en) | 2001-03-23 | 2003-03-20 | Pease Matthew L. | Rolled minimally-invasive heart valves and methods of manufacture |
US6540782B1 (en) | 2000-02-02 | 2003-04-01 | Robert V. Snyders | Artificial heart valve |
US20030065386A1 (en) | 2001-09-28 | 2003-04-03 | Weadock Kevin Shaun | Radially expandable endoprosthesis device with two-stage deployment |
WO2003047468A1 (en) | 2001-10-11 | 2003-06-12 | Percutaneous Valve Technologies | Implantable prosthetic valve |
US20030139803A1 (en) | 2000-05-30 | 2003-07-24 | Jacques Sequin | Method of stenting a vessel with stent lumenal diameter increasing distally |
US20030139796A1 (en) | 1996-06-06 | 2003-07-24 | Jacques Sequin | Endoprosthesis deployment system for treating vascular bifurcations |
WO2003079928A2 (en) | 2002-03-21 | 2003-10-02 | Providence Health System-Oregon | Bioprosthesis and method for suturelessly making same |
WO2003013239A3 (en) | 2001-08-06 | 2003-10-02 | Peter Lamm | Method for the devitalisation of natural organs and/or for the preparation of extracellular matrices for tissue engineering |
EP1354569A1 (en) | 1996-05-08 | 2003-10-22 | SORIN BIOMEDICA S.p.A. | An angioplasty stent |
WO2003096935A1 (en) | 2002-05-16 | 2003-11-27 | Cook Incorporated | Flexible barb for anchoring a prosthesis |
US20040006380A1 (en) | 2002-07-05 | 2004-01-08 | Buck Jerrick C. | Stent delivery system |
US6682559B2 (en) | 2000-01-27 | 2004-01-27 | 3F Therapeutics, Inc. | Prosthetic heart valve |
WO2004016201A2 (en) | 2002-08-15 | 2004-02-26 | Cook Incorporated | Stent and method of forming a stent with integral barbs |
DE10301026A1 (en) | 2002-08-13 | 2004-02-26 | Markus Dr.med. Dr.disc.pol. Ferrari | Stent to be used for percutaneous insertion of artificial heart valve, comprising hook-shaped elements for exact positioning |
WO2004016200A1 (en) | 2002-08-15 | 2004-02-26 | Cook Incorporated | Implantable vascular device |
WO2004019825A1 (en) | 2002-08-13 | 2004-03-11 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Device for the implantation and fixing of heart valve prostheses |
EP1041943B1 (en) | 1997-12-24 | 2004-03-31 | Edwards Lifesciences Corporation | Kit and method for chemical fixation of stentless cardiac valvular bioprostheses |
WO2004026173A2 (en) | 2002-09-20 | 2004-04-01 | Edwards Lifesciences Corporation | Continuous heart valve support frame and method of manufacture |
WO2004026117A2 (en) | 2002-09-23 | 2004-04-01 | 3F Therapeutics, Inc. | Prosthetic mitral valve |
WO2004028399A2 (en) | 2002-06-28 | 2004-04-08 | Cook Incorporated | Thoracic deployment device |
US20040073289A1 (en) | 2002-08-23 | 2004-04-15 | William A. Cook Australia Pty. Ltd. | Asymmetric stent graft attachment |
US20040102855A1 (en) | 2002-11-21 | 2004-05-27 | Scimed Life Systems, Inc. | Anti-reflux stent |
US20040117004A1 (en) | 2002-05-16 | 2004-06-17 | Osborne Thomas A. | Stent and method of forming a stent with integral barbs |
DE10302447A1 (en) | 2003-01-21 | 2004-07-29 | pfm Produkte für die Medizin AG | Implantable device for closing holes or making connections in human or animal bodies has a contractable supporting structure formed from a single wire-like element |
US20040153145A1 (en) | 2002-11-26 | 2004-08-05 | Clemson University | Fixation method for bioprostheses |
US20040186558A1 (en) | 2001-02-05 | 2004-09-23 | Cook Incorporated | Implantable vascular device |
US20040186563A1 (en) | 2003-03-18 | 2004-09-23 | Lobbi Mario M. | Minimally-invasive heart valve with cusp positioners |
US20040193244A1 (en) | 2002-12-04 | 2004-09-30 | Cook Incorporated | Device and method for treating thoracic aorta |
WO2004082528A2 (en) | 2003-03-17 | 2004-09-30 | Cook Incorporated | Vascular valve with removable support component |
US20040210304A1 (en) | 1999-11-17 | 2004-10-21 | Corevalve, S.A. | Prosthetic valve for transluminal delivery |
US20040210307A1 (en) | 2003-04-18 | 2004-10-21 | Alexander Khairkhahan | Percutaneous transcatheter heart valve replacement |
WO2004096100A1 (en) | 2003-04-24 | 2004-11-11 | Cook Incorporated | Artificial valve prosthesis with improved flow dynamics |
US6821211B2 (en) | 2001-09-14 | 2004-11-23 | Golftech | Sport swing analysis system |
US6821297B2 (en) | 2000-02-02 | 2004-11-23 | Robert V. Snyders | Artificial heart valve, implantation instrument and method therefor |
DE10335948B3 (en) | 2003-08-04 | 2005-02-03 | Qualimed Innovative Medizinprodukte Gmbh | Stent for medical applications comprises a tubular support structure made from joined ring segments and twisted by a thread with ends guided into the support structure via a deviating unit and coupled by a connector |
US6861211B2 (en) | 1999-04-27 | 2005-03-01 | The Children's Hospital Of Philadelphia | Stabilization of implantable bioprosthetic devices |
US20050049692A1 (en) | 2003-09-02 | 2005-03-03 | Numamoto Michael J. | Medical device for reduction of pressure effects of cardiac tricuspid valve regurgitation |
US6872226B2 (en) | 2001-01-29 | 2005-03-29 | 3F Therapeutics, Inc. | Method of cutting material for use in implantable medical device |
US20050075776A1 (en) | 2002-11-28 | 2005-04-07 | Cho Young Shin | Shift control method and apparatus of an automatic transmission |
US20050075725A1 (en) | 2003-10-02 | 2005-04-07 | Rowe Stanton J. | Implantable prosthetic valve with non-laminar flow |
US20050096726A1 (en) | 2000-05-30 | 2005-05-05 | Jacques Sequin | Noncylindrical stent deployment system for treating vascular bifurcations |
US20050096735A1 (en) | 2003-10-31 | 2005-05-05 | Hikmat Hojeibane | Implantable valvular prosthesis |
US20050113910A1 (en) | 2002-01-04 | 2005-05-26 | David Paniagua | Percutaneously implantable replacement heart valve device and method of making same |
US20050119728A1 (en) | 2001-07-19 | 2005-06-02 | The Cleveland Clinic Foundation | Method for fixing tissue |
US20050119736A1 (en) | 2003-10-30 | 2005-06-02 | Peter Zilla | Bioprosthetic tissue preparation with synthetic hydrogels |
US20050137698A1 (en) | 2003-12-23 | 2005-06-23 | Amr Salahieh | Leaflet engagement elements and methods for use thereof |
US20050137689A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical, A Delware Corporation | Retrievable heart valve anchor and method |
US20050137697A1 (en) | 2003-12-23 | 2005-06-23 | Amr Salahieh | Leaflet engagement elements and methods for use thereof |
US20050137688A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical, A Delaware Corporation | Repositionable heart valve and method |
US20050137687A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Heart valve anchor and method |
US20050137690A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Low profile heart valve and delivery system |
US20050137702A1 (en) | 2003-12-23 | 2005-06-23 | Haug Ulrich R. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US20050143804A1 (en) | 2001-10-17 | 2005-06-30 | Haverkost Patrick A. | Method and system for fixation of endoluminal devices |
US20050149166A1 (en) | 2003-11-08 | 2005-07-07 | Schaeffer Darin G. | Branch vessel prosthesis with anchoring device and method |
WO2005063980A1 (en) | 2003-12-31 | 2005-07-14 | Toudai Tlo, Ltd. | METHOD OF ENZYMATICALLY CONSTRUCTING RNAi LIBRARY |
WO2005062980A2 (en) | 2003-12-23 | 2005-07-14 | Sadra Medical, Inc. | Repositionable heart valve |
WO2005070343A1 (en) | 2003-12-23 | 2005-08-04 | Laboratoires Perouse | Kit which is intended to be implanted in a conduit |
WO2005072654A1 (en) | 2004-01-23 | 2005-08-11 | Edwards Lifesciences Corporation | Anatomically approximate prosthetic mitral heart valve |
US20050197695A1 (en) | 2004-03-03 | 2005-09-08 | Sorin Biomedica Cardio S.R.L. | Minimally-invasive cardiac-valve prosthesis |
US20050234546A1 (en) | 2004-02-05 | 2005-10-20 | Alan Nugent | Transcatheter delivery of a replacement heart valve |
US20050267560A1 (en) | 2000-02-03 | 2005-12-01 | Cook Incorporated | Implantable bioabsorbable valve support frame |
US20060025857A1 (en) | 2004-04-23 | 2006-02-02 | Bjarne Bergheim | Implantable prosthetic valve |
US20060047343A1 (en) | 2004-08-24 | 2006-03-02 | Oviatt Henry W | Anti-calcification treatments for heart valves and vascular grafts |
US7018406B2 (en) | 1999-11-17 | 2006-03-28 | Corevalve Sa | Prosthetic valve for transluminal delivery |
US20060074484A1 (en) | 2004-10-02 | 2006-04-06 | Huber Christoph H | Methods and devices for repair or replacement of heart valves or adjacent tissue without the need for full cardiopulmonary support |
US20060074485A1 (en) | 2004-05-17 | 2006-04-06 | Fidel Realyvasquez | Method and apparatus for percutaneous valve repair |
US7050276B2 (en) | 2002-06-13 | 2006-05-23 | Alps Electric Co., Ltd. | GMR magnetic sensing element having an antiferromagnetic layer extending beyond the track width and method for making the same |
US20060111770A1 (en) | 1999-06-02 | 2006-05-25 | Dusan Pavcnik | Implantable vascular device comprising a bioabsorbable frame |
WO2006066327A1 (en) | 2004-12-24 | 2006-06-29 | Celxcel Pty Ltd | An implantable biomaterial and a method of producing same |
US20060149360A1 (en) | 2003-07-08 | 2006-07-06 | Ventor Technologies Ltd. | Fluid flow prosthetic device |
US20060155366A1 (en) | 2005-01-10 | 2006-07-13 | Laduca Robert | Apparatus and method for deploying an implantable device within the body |
US7078163B2 (en) | 2001-03-30 | 2006-07-18 | Medtronic, Inc. | Process for reducing mineralization of tissue used in transplantation |
CA2595233A1 (en) | 2005-01-20 | 2006-07-27 | Fraunhofer Gesellschaft Zur Forderung Der Angewandten Forschung E.V. | Catheter for the transvascular implantation of prosthetic heart valves |
US20060178740A1 (en) | 2005-02-10 | 2006-08-10 | Sorin Biomedica Cardio S.R.L. | Cardiac-valve prosthesis |
US20060210597A1 (en) | 2005-03-19 | 2006-09-21 | Cook Biotech Incorporated | Prosthetic implants including ECM composite material |
US20060229718A1 (en) | 2005-04-06 | 2006-10-12 | Salvador Marquez | Stress absorbing flexible heart valve frame |
US20060246584A1 (en) | 2002-08-01 | 2006-11-02 | Bruno Covelli | In-vitro method for the production of a homologous stented tissue-engineered heart valve |
US20060259136A1 (en) | 2005-05-13 | 2006-11-16 | Corevalve Sa | Heart valve prosthesis and methods of manufacture and use |
US20060259134A1 (en) | 2003-07-08 | 2006-11-16 | Ehud Schwammenthal | Implantable prosthetic devices particularly for transarterial delivery in the treatment of aortic stenosis, and methods of implanting such devices |
US20060259137A1 (en) | 2003-10-06 | 2006-11-16 | Jason Artof | Minimally invasive valve replacement system |
US7141064B2 (en) | 2002-05-08 | 2006-11-28 | Edwards Lifesciences Corporation | Compressed tissue for heart valve leaflets |
WO2006127756A2 (en) | 2005-05-24 | 2006-11-30 | Edwards Lifesciences Corporation | Rapid deployment prosthetic heart valve |
US20060271161A1 (en) | 2005-05-26 | 2006-11-30 | Boston Scientific Scimed, Inc. | Selective treatment of stent side branch petals |
WO2006127765A1 (en) | 2005-05-24 | 2006-11-30 | Corevalve, Inc. | A non-cylindrical prosthetic valve system for transluminal delivery |
WO2006132948A1 (en) | 2005-06-03 | 2006-12-14 | Arbor Surgical Technologies, Inc. | Apparatus and methods for making leaflets and valve prostheses including such leaflets |
US20060290027A1 (en) | 1999-12-08 | 2006-12-28 | O'connor Bernard | Heart valve prosthesis and method of manufacture |
US20070005132A1 (en) | 2002-11-26 | 2007-01-04 | Simionescu Dan T | Tissue material and process for bioprosthesis |
US20070005131A1 (en) | 2005-06-13 | 2007-01-04 | Taylor David M | Heart valve delivery system |
US20070021826A1 (en) | 2003-04-24 | 2007-01-25 | Cook Incorporated | Intralumenally implantable frames |
US20070020248A1 (en) | 2005-03-01 | 2007-01-25 | Everaerts Frank J L | Process for biological tissue |
US20070027535A1 (en) | 2005-07-28 | 2007-02-01 | Cook Incorporated | Implantable thromboresistant valve |
US20070032856A1 (en) | 2002-09-30 | 2007-02-08 | Advanced Cardiovascular Systems, Inc. | Drug eluting stent |
US20070038295A1 (en) | 2005-08-12 | 2007-02-15 | Cook Incorporated | Artificial valve prosthesis having a ring frame |
US20070038291A1 (en) | 2003-04-24 | 2007-02-15 | Cook Incorporated | Intralumenally-implantable frames |
US20070050014A1 (en) | 2005-08-31 | 2007-03-01 | Johnson Chad E | Implantable valve |
US20070088431A1 (en) | 2005-10-18 | 2007-04-19 | Henry Bourang | Heart valve delivery system with valve catheter |
WO2007047945A2 (en) | 2005-10-21 | 2007-04-26 | Cook Incorporated | Artificial valve with center leaflet attachment |
AU2006308187A1 (en) | 2005-10-28 | 2007-05-03 | Jenavalve Technology Inc. | Device for implanting and fastening heart valve prostheses |
US20070100435A1 (en) | 2003-04-24 | 2007-05-03 | Cook Incorporated | Artificial prostheses with preferred geometries |
AU2006310681A1 (en) | 2005-11-04 | 2007-05-10 | Jenavalve Technology Inc. | Self-expandable medical instrument for treatment of defects on a patient's heart |
US20070112422A1 (en) | 2005-11-16 | 2007-05-17 | Mark Dehdashtian | Transapical heart valve delivery system and method |
US20070123979A1 (en) | 2005-06-27 | 2007-05-31 | Patrick Perier | Apparatus, system, and method for treatment of posterior leaflet prolapse |
US20070123700A1 (en) | 2004-06-01 | 2007-05-31 | Yuichiro Ueda | Processes for removing cells and cell debris from tissue and tissue constructs used in transplantation and tissue reconstruction |
DE202007005491U1 (en) | 2007-04-13 | 2007-06-14 | Jenavalve Technology Gmbh | Medical device for treating aortic valve insufficiency of patient, has self-expandable endoprosthesis for positioning and fixing heart valve implant in arota of patient, and retaining segment with brackets for receiving implant |
WO2007071436A2 (en) | 2005-12-22 | 2007-06-28 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
US20070162103A1 (en) | 2001-02-05 | 2007-07-12 | Cook Incorporated | Implantable device with remodelable material and covering material |
WO2007098232A2 (en) | 2006-02-21 | 2007-08-30 | Med Institute, Inc. | Split sheath deployment system |
US20070213813A1 (en) | 2005-12-22 | 2007-09-13 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
US20070239271A1 (en) | 2006-04-10 | 2007-10-11 | Than Nguyen | Systems and methods for loading a prosthesis onto a minimally invasive delivery system |
US20070244551A1 (en) | 2006-04-14 | 2007-10-18 | Robert Stobie | Holders for prosthetic aortic heart valves |
US20070288087A1 (en) | 2006-05-30 | 2007-12-13 | Cook Incorporated | Artificial valve prosthesis |
EP1878407A1 (en) | 2006-07-12 | 2008-01-16 | Efstathios-Andreas Agathos | Human cardiac valve replacement with seal heart valve (aortic or pulmonary) |
US20080021546A1 (en) | 2006-07-18 | 2008-01-24 | Tim Patz | System for deploying balloon-expandable heart valves |
US20080033534A1 (en) | 2002-05-16 | 2008-02-07 | Cook Incorporated | Flexible Barb for Anchoring a Prosthesis |
GB2440809A (en) | 2006-07-28 | 2008-02-13 | Geoffrey Douglas Tansley | Prosthetic heart valve with leaflets curved by residual stresses |
US20080065011A1 (en) | 2006-09-08 | 2008-03-13 | Philippe Marchand | Integrated heart valve delivery system |
EP1900343A2 (en) | 2000-01-31 | 2008-03-19 | Cook Biotech, Inc. | Stent valves and uses of same |
US20080071369A1 (en) | 2006-09-19 | 2008-03-20 | Yosi Tuval | Valve fixation member having engagement arms |
US20080086205A1 (en) | 2006-10-10 | 2008-04-10 | Celonova Biosciences, Inc. | Bioprosthetic Heart Valve With Polyphosphazene |
US20080102439A1 (en) | 2006-10-27 | 2008-05-01 | Bin Tian | Biological tissue for surgical implantation |
US20080140189A1 (en) | 2006-12-06 | 2008-06-12 | Corevalve, Inc. | System and method for transapical delivery of an annulus anchored self-expanding valve |
US20080154355A1 (en) | 2006-12-22 | 2008-06-26 | Netanel Benichou | Implantable prosthetic valve assembly and method of making the same |
WO2008101083A2 (en) | 2007-02-15 | 2008-08-21 | Cook Incorporated | Artificial valve prostheses with a free leaflet portion |
EP1980220A1 (en) | 2007-04-13 | 2008-10-15 | JenaValve Technology GmbH | Medical device for treating a heart valve insufficiency or stenosis |
US20080255660A1 (en) | 2007-04-13 | 2008-10-16 | Volker Guyenot | Medical device for treating a heart valve insufficiency |
US20080255661A1 (en) | 2007-04-13 | 2008-10-16 | Helmut Straubinger | Medical device for treating a heart valve insufficiency or stenosis |
WO2008125153A1 (en) | 2007-04-13 | 2008-10-23 | Jenavalve Technology Inc. | Medical device for treating a heart valve insufficiency or stenosis |
WO2008138584A1 (en) | 2007-05-15 | 2008-11-20 | Jenavalve Technology Inc. | Handle for manipulating a catheter tip, catheter system and medical insertion system for inserting a self-expandable heart valve stent |
WO2008150529A1 (en) | 2007-06-04 | 2008-12-11 | St. Jude Medical, Inc. | Prosthetic heart valves |
US20090216313A1 (en) | 2008-02-26 | 2009-08-27 | Helmut Straubinger | Stent for the positioning and anchoring of a valvular prosthesis |
US20090216310A1 (en) | 2008-02-26 | 2009-08-27 | Helmut Straubinger | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US20100249917A1 (en) | 2009-03-30 | 2010-09-30 | Ji Zhang | Methods for Delivery of a Sutureless Pulmonary or Mitral Valve |
US20100292779A1 (en) | 2009-05-15 | 2010-11-18 | Helmut Straubinger | Device for compressing a stent and a system as well as a method for loading a stent into a medical delivery system |
US20110106244A1 (en) | 2008-01-25 | 2011-05-05 | Markus Ferrari | Medical apparatus for the therapeutic treatment of an insufficient cardiac valve |
US20110288626A1 (en) | 2010-05-20 | 2011-11-24 | Helmut Straubinger | Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect |
US20110295363A1 (en) | 2010-05-25 | 2011-12-01 | Girard Michael J | Prosthetic Heart Valve And Transcatheter Delivered Endoprosthesis Comprising A Prosthetic Heart Valve And A Stent |
US8398704B2 (en) | 2008-02-26 | 2013-03-19 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US20130079869A1 (en) | 2008-02-26 | 2013-03-28 | Helmut Straubinger | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US8465540B2 (en) | 2008-02-26 | 2013-06-18 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5584803A (en) | 1991-07-16 | 1996-12-17 | Heartport, Inc. | System for cardiac procedures |
US5728152A (en) * | 1995-06-07 | 1998-03-17 | St. Jude Medical, Inc. | Bioresorbable heart valve support |
US6273876B1 (en) | 1997-12-05 | 2001-08-14 | Intratherapeutics, Inc. | Catheter segments having circumferential supports with axial projection |
US20040044350A1 (en) | 1999-04-09 | 2004-03-04 | Evalve, Inc. | Steerable access sheath and methods of use |
US6623518B2 (en) | 2001-02-26 | 2003-09-23 | Ev3 Peripheral, Inc. | Implant delivery system with interlock |
US7264632B2 (en) | 2002-06-07 | 2007-09-04 | Medtronic Vascular, Inc. | Controlled deployment delivery system |
US20050137691A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Two piece heart valve and anchor |
US7405259B2 (en) | 2005-04-29 | 2008-07-29 | Momentive Performance Materials Inc. | Silylated polymer derived from butadiene and solvent-resistant pressure sensitive adhesive composition containing same |
-
2005
- 2005-10-28 DE DE102005051849A patent/DE102005051849B4/en not_active Expired - Fee Related
-
2006
- 2006-10-17 DK DK06828826.5T patent/DK1940321T3/en active
- 2006-10-17 PL PL06828826T patent/PL1940321T3/en unknown
- 2006-10-17 ES ES06828826T patent/ES2355583T3/en active Active
- 2006-10-17 JP JP2008536976A patent/JP4904361B2/en active Active
- 2006-10-17 PT PT06828826T patent/PT1940321E/en unknown
- 2006-10-17 SI SI200630907T patent/SI1940321T1/en unknown
- 2006-10-17 EP EP06828826A patent/EP1940321B1/en active Active
- 2006-10-17 AU AU2006308187A patent/AU2006308187C1/en not_active Ceased
- 2006-10-17 AT AT06828826T patent/ATE491413T1/en active
- 2006-10-17 CA CA2627409A patent/CA2627409C/en not_active Expired - Fee Related
- 2006-10-17 WO PCT/EP2006/010023 patent/WO2007048529A1/en active Application Filing
- 2006-10-17 DE DE502006008528T patent/DE502006008528D1/en active Active
- 2006-10-30 US US11/589,570 patent/US8092521B2/en not_active Ceased
-
2011
- 2011-02-15 CY CY20111100188T patent/CY1111205T1/en unknown
- 2011-12-09 US US13/315,913 patent/US8551160B2/en not_active Ceased
-
2013
- 2013-09-06 US US14/020,497 patent/US9044320B2/en active Active
- 2013-11-22 US US14/087,316 patent/US8834561B2/en active Active
-
2014
- 2014-08-07 US US14/454,334 patent/USRE45962E1/en active Active
- 2014-08-07 US US14/454,285 patent/USRE45790E1/en active Active
-
2015
- 2015-05-11 US US14/708,892 patent/US9402717B2/en active Active
-
2016
- 2016-06-28 US US15/195,625 patent/US9855142B2/en active Active
-
2017
- 2017-11-22 US US15/821,012 patent/US10363134B2/en active Active
-
2019
- 2019-06-17 US US16/442,793 patent/US11116628B2/en active Active
Patent Citations (481)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0084395A1 (en) | 1982-01-20 | 1983-07-27 | Martin Morris Black | Artificial heart valves |
US4922905A (en) | 1985-11-30 | 1990-05-08 | Strecker Ernst P | Dilatation catheter |
US5061277A (en) | 1986-08-06 | 1991-10-29 | Baxter International Inc. | Flexible cardiac valvular support prosthesis |
US5061277B1 (en) | 1986-08-06 | 2000-02-29 | Baxter Travenol Lab | Flexible cardiac valvular support prosthesis |
US5679112A (en) | 1988-04-01 | 1997-10-21 | The Board Of Regents Of The University Of Michigan | Calcification-resistant materials and methods of making same through use of multivalent cations |
US5094661A (en) | 1988-04-01 | 1992-03-10 | The University Of Michigan | Calcification-resistant materials and methods of making same through use of trivalent aluminum |
US5746775A (en) | 1988-04-01 | 1998-05-05 | The Board Of Regent6S Of The University Of Michigan | Method of making calcification-resistant bioprosthetic tissue |
US5368608A (en) | 1988-04-01 | 1994-11-29 | University Of Michigan, The Board Of Regents | Calcification-resistant materials and methods of making same through use of multivalent cations |
US5104407A (en) | 1989-02-13 | 1992-04-14 | Baxter International Inc. | Selectively flexible annuloplasty ring |
US5104407B1 (en) | 1989-02-13 | 1999-09-21 | Baxter Int | Selectively flexible annuloplasty ring |
EP0458877B1 (en) | 1989-02-17 | 1995-05-17 | Baxter International Inc. | Calcification mitigation of bioprosthetic implants |
US5002566A (en) | 1989-02-17 | 1991-03-26 | Baxter International Inc. | Calcification mitigation of bioprosthetic implants |
WO1990009102A1 (en) | 1989-02-17 | 1990-08-23 | Baxter International Inc. | Calcification mitigation of bioprosthetic implants |
US5352240A (en) | 1989-05-31 | 1994-10-04 | Promedica International, Inc. | Human heart valve replacement with porcine pulmonary valve |
EP0402036B1 (en) | 1989-05-31 | 1996-04-03 | ROSS, Donald N. | Human heart valve replacement with porcine pulmonary valve |
US5279612A (en) | 1989-06-09 | 1994-01-18 | Medtronic, Inc. | Dynamic fixation of porcine aortic valves |
EP0402176B1 (en) | 1989-06-09 | 1994-04-27 | Medtronic, Inc. | Dynamic fixation of porcine aortic valves |
US6168614B1 (en) | 1990-05-18 | 2001-01-02 | Heartport, Inc. | Valve prosthesis for implantation in the body |
US20030036795A1 (en) | 1990-05-18 | 2003-02-20 | Andersen Henning Rud | Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis |
US5840081A (en) | 1990-05-18 | 1998-11-24 | Andersen; Henning Rud | System and method for implanting cardiac valves |
EP0592410B1 (en) | 1990-05-18 | 1995-10-11 | ANDERSEN, Henning Rud | A valve prosthesis for implantation in the body and a catheter for implantating such valve prosthesis |
US5411552A (en) | 1990-05-18 | 1995-05-02 | Andersen; Henning R. | Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis |
US6582462B1 (en) | 1990-05-18 | 2003-06-24 | Heartport, Inc. | Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis |
EP0547135B1 (en) | 1990-09-07 | 2002-01-09 | Edwards Lifesciences Corporation | Stentless heart valve |
US5336258A (en) | 1990-09-07 | 1994-08-09 | Baxter International Inc. | Stentless heart valve and holder |
US5197979A (en) | 1990-09-07 | 1993-03-30 | Baxter International Inc. | Stentless heart valve and holder |
US5713953A (en) | 1991-05-24 | 1998-02-03 | Sorin Biomedica Cardio S.P.A. | Cardiac valve prosthesis particularly for replacement of the aortic valve |
EP0515324A1 (en) | 1991-05-24 | 1992-11-25 | SORIN BIOMEDICA CARDIO S.p.A. | A cardiac valve prosthesis, particularly for replacement of the aortic valve |
US5456713A (en) | 1991-10-25 | 1995-10-10 | Cook Incorporated | Expandable transluminal graft prosthesis for repairs of aneurysm and method for implanting |
US5755777A (en) | 1991-10-25 | 1998-05-26 | Cook Incorporated | Expandable transluminal graft prosthesis for repair of aneurysm |
US5332402A (en) | 1992-05-12 | 1994-07-26 | Teitelbaum George P | Percutaneously-inserted cardiac valve |
EP0729364B1 (en) | 1993-10-21 | 2002-01-16 | The Regents Of The University Of Michigan | Method of making calcification-resistant bioprosthetic tissue |
WO1995011055A1 (en) | 1993-10-22 | 1995-04-27 | Scimed Lifesystems, Inc. | Improved stent delivery apparatus and method |
US6077297A (en) | 1993-11-04 | 2000-06-20 | C. R. Bard, Inc. | Non-migrating vascular prosthesis and minimally invasive placement system therefor |
US5509930A (en) | 1993-12-17 | 1996-04-23 | Autogenics | Stentless heart valve |
US5632778A (en) | 1994-03-14 | 1997-05-27 | Cryolife, Inc. | Treated tissue for implantation and methods of preparation |
EP1452153A1 (en) | 1994-03-14 | 2004-09-01 | Cryolife, Inc | Treated tissue for implantation and preparation methods |
WO1995024873A1 (en) | 1994-03-14 | 1995-09-21 | Cryolife, Inc. | Treated tissue for implantation and preparation methods |
EP0871414B1 (en) | 1994-03-14 | 2004-04-28 | Cryolife, Inc | Preparation methods of tissue for implantation |
US5613982A (en) | 1994-03-14 | 1997-03-25 | Cryolife, Inc. | Method of preparing transplant tissue to reduce immunogenicity upon implantation |
US5899936A (en) | 1994-03-14 | 1999-05-04 | Cryolife, Inc. | Treated tissue for implantation and methods of preparation |
US5595571A (en) | 1994-04-18 | 1997-01-21 | Hancock Jaffe Laboratories | Biological material pre-fixation treatment |
EP0756498B1 (en) | 1994-04-18 | 2002-07-24 | Hancock Jaffe Laboratories | Biological material pre-fixation treatment |
US5843181A (en) | 1994-04-18 | 1998-12-01 | Hancock Jaffe Laboratories | Biological material pre-fixation treatment |
WO1995028183A1 (en) | 1994-04-18 | 1995-10-26 | Hancock Jaffe Laboratories | Biological material pre-fixation treatment |
US5683451A (en) | 1994-06-08 | 1997-11-04 | Cardiovascular Concepts, Inc. | Apparatus and methods for deployment release of intraluminal prostheses |
US6126685A (en) | 1994-06-08 | 2000-10-03 | Medtronic, Inc. | Apparatus and methods for placement and repositioning of intraluminal prostheses |
US5824041A (en) | 1994-06-08 | 1998-10-20 | Medtronic, Inc. | Apparatus and methods for placement and repositioning of intraluminal prostheses |
US6350278B1 (en) | 1994-06-08 | 2002-02-26 | Medtronic Ave, Inc. | Apparatus and methods for placement and repositioning of intraluminal prostheses |
US5697972A (en) | 1994-07-13 | 1997-12-16 | Korea Institute Of Science And Technology | Bioprosthetic heart valves having high calcification resistance |
EP0778775B1 (en) | 1994-09-01 | 1999-01-20 | PHARMACIA & UPJOHN COMPANY | Cosolvent parenteral formulation of tirilazad |
US5549666A (en) | 1994-09-02 | 1996-08-27 | Baxter International Inc. | Natural tissue valve prostheses having variably complaint leaflets |
WO1996013227A1 (en) | 1994-10-21 | 1996-05-09 | University Of Michigan | Calcification-resistant bioprosthetic tissue and methods of making same |
EP0786970B1 (en) | 1994-10-21 | 2005-12-07 | The University Of Michigan | Calcification-resistant bioprosthetic tissue and methods of making same |
US5674298A (en) | 1994-10-21 | 1997-10-07 | The Board Of Regents Of The University Of Michigan | Calcification-resistant bioprosthetic tissue and methods of making same |
US5824080A (en) | 1995-09-28 | 1998-10-20 | The General Hospital Corporation | Photochemistry for the preparation of biologic grafts--allografts and xenografts |
DE19546692A1 (en) | 1995-12-14 | 1997-06-19 | Figulla Hans Reiner Prof Dr Me | Self-expandable heart valve bio-prosthesis or synthetic polyurethane valve |
DE19546692C2 (en) | 1995-12-14 | 2002-11-07 | Hans-Reiner Figulla | Self-expanding heart valve prosthesis for implantation in the human body via a catheter system |
US5880242A (en) | 1996-03-04 | 1999-03-09 | Baxter International Inc. | Nonpolymeric epoxy compounds for cross linking biological tissue and bioprosthetic grafts prepared thereby |
EP0888142B1 (en) | 1996-03-04 | 2003-05-28 | Edwards Lifesciences Corporation | Nonpolymeric epoxy compounds for cross-linking biological tissue and bioprosthetic grafts prepared thereby |
WO1997032615A1 (en) | 1996-03-04 | 1997-09-12 | Baxter International Inc. | Nonpolymeric epoxy compounds for cross-linking biological tissue and bioprosthetic grafts prepared thereby |
EP1354569A1 (en) | 1996-05-08 | 2003-10-22 | SORIN BIOMEDICA S.p.A. | An angioplasty stent |
US20030139796A1 (en) | 1996-06-06 | 2003-07-24 | Jacques Sequin | Endoprosthesis deployment system for treating vascular bifurcations |
EP0928615A1 (en) | 1996-06-12 | 1999-07-14 | A.S.A. Sangyo CO., Ltd. | Method for recovering and regenerating peritoneal dialyzate, apparatus therefor, and attachments thereof |
US6908481B2 (en) | 1996-12-31 | 2005-06-21 | Edwards Lifesciences Pvt, Inc. | Value prosthesis for implantation in body channels |
US20030014104A1 (en) | 1996-12-31 | 2003-01-16 | Alain Cribier | Value prosthesis for implantation in body channels |
EP2000115A2 (en) | 1996-12-31 | 2008-12-10 | Edwards Lifesciences PVT, Inc. | Valve prosthesis for implantation in body channels |
US20080077236A1 (en) | 1996-12-31 | 2008-03-27 | Brice Letac | Valve prosthesis for implantation in body channels |
US20030109924A1 (en) * | 1996-12-31 | 2003-06-12 | Alain Cribier | Implanting a valve prosthesis in body channels |
US5841382A (en) | 1997-03-19 | 1998-11-24 | Lucent Technologies Inc. | Fast testing of D/A converters |
US6585766B1 (en) | 1997-03-27 | 2003-07-01 | Edwards Lifesciences Corporation | Cloth-covered stents for tissue heart valves |
WO1998043556A1 (en) | 1997-03-27 | 1998-10-08 | Baxter International Inc. | Natural tissue heart valves and methods of making same |
US6945997B2 (en) | 1997-03-27 | 2005-09-20 | Edwards Lifesciences Corporation | Heart valves and suture rings therefor |
US20030195620A1 (en) | 1997-03-27 | 2003-10-16 | Huynh Van Le | Heart valves and suture rings therefor |
US6102944A (en) | 1997-03-27 | 2000-08-15 | Edwards Lifesciences Corporation | Methods of tissue heart valve assembly |
EP0971649B1 (en) | 1997-03-27 | 2002-12-18 | Edwards Lifesciences Corporation | Natural tissue heart valves and methods of making same |
US5928281A (en) | 1997-03-27 | 1999-07-27 | Baxter International Inc. | Tissue heart valves |
US20060009842A1 (en) | 1997-03-27 | 2006-01-12 | Huynh Van L | Contoured heart valve suture rings |
EP0987998B1 (en) | 1997-04-11 | 2004-10-13 | CryoLife, Inc. | Tissue decellularization |
WO1998046165A1 (en) | 1997-04-11 | 1998-10-22 | Cryolife, Inc. | Tissue decellularization |
US7318998B2 (en) | 1997-04-11 | 2008-01-15 | Cryolife, Inc. | Tissue decellularization |
US5957949A (en) | 1997-05-01 | 1999-09-28 | World Medical Manufacturing Corp. | Percutaneous placement valve stent |
US5876434A (en) | 1997-07-13 | 1999-03-02 | Litana Ltd. | Implantable medical devices of shape memory alloy |
EP1017868B1 (en) | 1997-07-15 | 2003-09-03 | Litana Ltd. | Implantable medical devices of shape memory alloy |
EP1281357A2 (en) | 1997-09-26 | 2003-02-05 | Duke University | Perfusion-occlusion catheter and methods |
US6572642B2 (en) | 1997-12-10 | 2003-06-03 | Sorin Biomedica Cardio S.P.A. | Method for treating a prosthesis having an apertured structure and associated devices |
US6379740B1 (en) | 1997-12-10 | 2002-04-30 | Sorin Biomedica Cardio S.P.A. | Method for treating a prosthesis having an apertured structure and associated devices |
US6342070B1 (en) | 1997-12-24 | 2002-01-29 | Edwards Lifesciences Corp. | Stentless bioprosthetic heart valve with patent coronary protuberances and method of surgical use thereof |
EP1041942B1 (en) | 1997-12-24 | 2006-06-14 | Edwards Lifesciences Corporation | Stentless bioprosthetic heart valve with coronary protuberances |
EP1041943B1 (en) | 1997-12-24 | 2004-03-31 | Edwards Lifesciences Corporation | Kit and method for chemical fixation of stentless cardiac valvular bioprostheses |
US6001126A (en) | 1997-12-24 | 1999-12-14 | Baxter International Inc. | Stentless bioprosthetic heart valve with coronary protuberances and related methods for surgical repair of defective heart valves |
WO1999037337A3 (en) | 1998-01-27 | 1999-09-30 | St Jude Medical | Prostheses with associated growth factors |
EP1051204B1 (en) | 1998-01-27 | 2006-12-06 | St. Jude Medical, Inc. | Prostheses with associated growth factors |
US6093530A (en) | 1998-02-06 | 2000-07-25 | Sulzer Carbomedics Inc. | Non-calcific biomaterial by glutaraldehyde followed by oxidative fixation |
EP0986348B1 (en) | 1998-03-31 | 2002-09-04 | Shlomo Gabbay | Natural tissue heart valve prosthesis |
US5935163A (en) | 1998-03-31 | 1999-08-10 | Shelhigh, Inc. | Natural tissue heart valve prosthesis |
US6974474B2 (en) | 1998-06-02 | 2005-12-13 | Cook Incorporated | Multiple-sided intraluminal medical device |
US6200336B1 (en) | 1998-06-02 | 2001-03-13 | Cook Incorporated | Multiple-sided intraluminal medical device |
EP1087727B1 (en) | 1998-06-02 | 2004-11-10 | Cook Incorporated | Multiple-sided intraluminal medical device |
US20030125795A1 (en) | 1998-06-02 | 2003-07-03 | Cook Incorporated | Multiple-sided intraluminal medical device |
US6508833B2 (en) | 1998-06-02 | 2003-01-21 | Cook Incorporated | Multiple-sided intraluminal medical device |
US20010011187A1 (en) | 1998-06-02 | 2001-08-02 | Dusan Pavcnik | Multiple-sided intraluminal medical device |
US6613086B1 (en) | 1998-06-24 | 2003-09-02 | Carbomedics Inc. | Altering heart valve leaflet attachment geometry to influence the location and magnitude of maximum loaded stress on the leaflet |
EP1089676A2 (en) | 1998-06-24 | 2001-04-11 | Sulzer Carbomedics Inc. | Altering heart valve leaflet attachment geometry to influence the location and magnitude of maximum loaded stress on the leaflet |
US6117169A (en) | 1998-06-24 | 2000-09-12 | Sulzer Carbomedics Inc. | Living hinge attachment of leaflet to a valve body |
WO1999066863A9 (en) | 1998-06-24 | 2001-06-28 | Sulzer Carbomedics Inc | Altering heart valve leaflet attachment geometry to influence the location and magnitude of maximum loaded stress on the leaflet |
US6558417B2 (en) | 1998-06-26 | 2003-05-06 | St. Jude Medical, Inc. | Single suture biological tissue aortic stentless valve |
US6254636B1 (en) | 1998-06-26 | 2001-07-03 | St. Jude Medical, Inc. | Single suture biological tissue aortic stentless valve |
US20080262602A1 (en) | 1998-09-10 | 2008-10-23 | Jenavalve Technology, Inc. | Methods and conduits for flowing blood from a heart chamber to a blood vessel |
EP1112042B1 (en) | 1998-09-10 | 2007-11-14 | JenaValve Technology, Inc. | Transmyocardial shunt |
EP1886649A2 (en) | 1998-09-10 | 2008-02-13 | JenaValve Technology, Inc. | Transmyocardial shunt |
US20130144203A1 (en) | 1998-09-10 | 2013-06-06 | Jenavalve Technology, Inc. | Methods And Conduits For Flowing Blood From A Heart Chamber To A Blood Vessel |
JP2005118585A (en) | 1998-09-10 | 2005-05-12 | Percardia Inc | Transmyocardial shunt |
US20050033220A1 (en) | 1998-09-10 | 2005-02-10 | Percardia, Inc. | Left ventricular conduit with blood vessel graft |
US6254564B1 (en) | 1998-09-10 | 2001-07-03 | Percardia, Inc. | Left ventricular conduit with blood vessel graft |
WO2000015148A8 (en) | 1998-09-10 | 2001-03-22 | Percardia Inc | Transmyocardial shunt made with a blood vessel graft for left ventricular revascularization |
JP2007296375A (en) | 1998-09-10 | 2007-11-15 | Jenavalve Technology Inc | Transmyocardial shunt |
US6881199B2 (en) | 1998-09-10 | 2005-04-19 | Percardia, Inc. | Left ventricular conduit with blood vessel graft |
EP1117446B1 (en) | 1998-09-30 | 2004-11-24 | Medtronic, Inc. | Process for reducing mineralization of tissue used in transplantation |
US6509145B1 (en) | 1998-09-30 | 2003-01-21 | Medtronic, Inc. | Process for reducing mineralization of tissue used in transplantation |
WO2000018445A1 (en) | 1998-09-30 | 2000-04-06 | Medtronic, Inc. | Process for reducing mineralization of tissue used in transplantation |
US6214055B1 (en) | 1998-10-30 | 2001-04-10 | Mures Cardiovascular Research, Inc. | Method and kit for rapid preparation of autologous tissue medical devices |
WO2000025702A1 (en) | 1998-11-03 | 2000-05-11 | Jacques Seguin | Prosthesis for corporeal duct, in particular vascular stent |
DE19857887B4 (en) | 1998-12-15 | 2005-05-04 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anchoring support for a heart valve prosthesis |
DE19857887A1 (en) | 1998-12-15 | 2000-07-06 | Fraunhofer Ges Forschung | Anchoring support for a heart valve prosthesis comprises a single-piece component which is formed of rod shaped elements made of a memory metal, and has at least in part a lattice structure |
US20040148018A1 (en) | 1999-01-26 | 2004-07-29 | Carpentier Alain F. | Flexible heart valve and associated connecting band |
US6736845B2 (en) | 1999-01-26 | 2004-05-18 | Edwards Lifesciences Corporation | Holder for flexible heart valve |
US20020055775A1 (en) | 1999-01-26 | 2002-05-09 | Alain F. Carpentier | Flexible heart valve |
US20020133226A1 (en) | 1999-01-26 | 2002-09-19 | Salvador Marquez | Holder for flexible heart valve |
US6338740B1 (en) | 1999-01-26 | 2002-01-15 | Edwards Lifesciences Corporation | Flexible heart valve leaflets |
US6558418B2 (en) | 1999-01-26 | 2003-05-06 | Edwards Lifesciences Corporation | Flexible heart valve |
US20020151970A1 (en) | 1999-02-10 | 2002-10-17 | Garrison Michi E. | Methods and devices for implanting cardiac valves |
EP1164976A4 (en) | 1999-02-10 | 2005-03-16 | Heartport Inc | Methods and devices for implanting cardiac valves |
WO2000047139A1 (en) | 1999-02-10 | 2000-08-17 | Heartport, Inc. | Methods and devices for implanting cardiac valves |
US6425916B1 (en) | 1999-02-10 | 2002-07-30 | Michi E. Garrison | Methods and devices for implanting cardiac valves |
WO2000053125A1 (en) | 1999-03-10 | 2000-09-14 | Sulzer Carbomedics Inc. | Pre-stressed devices incorporating materials subject to stress softening |
US6287338B1 (en) | 1999-03-10 | 2001-09-11 | Sulzer Carbomedics Inc. | Pre-stressing devices incorporating materials subject to stress softening |
EP1158937A1 (en) | 1999-03-10 | 2001-12-05 | Sulzer Carbomedics Inc. | Pre-stressed devices incorporating materials subject to stress softening |
US6177514B1 (en) | 1999-04-09 | 2001-01-23 | Sulzer Carbomedics Inc. | Blocked functional reagants for cross-linking biological tissues |
EP1171061A1 (en) | 1999-04-15 | 2002-01-16 | Sulzer Carbomedics Inc. | Heart valve leaflet with scalloped free margin |
WO2000062714A1 (en) | 1999-04-15 | 2000-10-26 | Sulzer Carbomedics Inc. | Heart valve leaflet with scalloped free margin |
US6283995B1 (en) | 1999-04-15 | 2001-09-04 | Sulzer Carbomedics Inc. | Heart valve leaflet with scalloped free margin |
US6231602B1 (en) | 1999-04-16 | 2001-05-15 | Edwards Lifesciences Corporation | Aortic annuloplasty ring |
US6861211B2 (en) | 1999-04-27 | 2005-03-01 | The Children's Hospital Of Philadelphia | Stabilization of implantable bioprosthetic devices |
US6478819B2 (en) | 1999-05-27 | 2002-11-12 | Sulzer Carbomedics Inc. | Prosthetic heart valves with flexible post geometry |
US7452371B2 (en) | 1999-06-02 | 2008-11-18 | Cook Incorporated | Implantable vascular device |
US20060111770A1 (en) | 1999-06-02 | 2006-05-25 | Dusan Pavcnik | Implantable vascular device comprising a bioabsorbable frame |
US20010039450A1 (en) | 1999-06-02 | 2001-11-08 | Dusan Pavcnik | Implantable vascular device |
WO2001010209A1 (en) | 1999-08-11 | 2001-02-15 | Biomedical Design, Inc. | Sterilization of biological tissue |
EP1206179B1 (en) | 1999-08-11 | 2004-10-27 | Biomedical Design, Inc. | Sterilization of biological tissue |
US6521179B1 (en) | 1999-08-11 | 2003-02-18 | Biomedical Design, Inc. | Sterilization |
US6183481B1 (en) | 1999-09-22 | 2001-02-06 | Endomed Inc. | Delivery system for self-expanding stents and grafts |
US20020123790A1 (en) | 1999-09-28 | 2002-09-05 | White Geoffrey Hamilton | Enhanced engagement member for anchoring prosthetic devices in body lumen |
US7329278B2 (en) | 1999-11-17 | 2008-02-12 | Corevalve, Inc. | Prosthetic valve for transluminal delivery |
WO2001035870A1 (en) | 1999-11-17 | 2001-05-25 | Jacques Seguin | Device for replacing a cardiac valve by percutaneous route |
US20070043435A1 (en) | 1999-11-17 | 2007-02-22 | Jacques Seguin | Non-cylindrical prosthetic valve system for transluminal delivery |
EP1233731B1 (en) | 1999-11-17 | 2004-12-29 | Jacques Seguin | Device for replacing a cardiac valve by percutaneous route |
US7018406B2 (en) | 1999-11-17 | 2006-03-28 | Corevalve Sa | Prosthetic valve for transluminal delivery |
US20080133003A1 (en) | 1999-11-17 | 2008-06-05 | Jacques Seguin | Prosthetic valve for transluminal delivery |
US6830584B1 (en) | 1999-11-17 | 2004-12-14 | Jacques Seguin | Device for replacing a cardiac valve by percutaneous route |
US20040210304A1 (en) | 1999-11-17 | 2004-10-21 | Corevalve, S.A. | Prosthetic valve for transluminal delivery |
WO2001041679A1 (en) | 1999-12-08 | 2001-06-14 | Aortech Europe Limited | Hearth valve prosthesis and method of manufacture |
US20060290027A1 (en) | 1999-12-08 | 2006-12-28 | O'connor Bernard | Heart valve prosthesis and method of manufacture |
EP1235537B1 (en) | 1999-12-08 | 2008-12-31 | Aortech International PLC | Method of manufacture of a hearth valve prosthesis |
US20030023300A1 (en) | 1999-12-31 | 2003-01-30 | Bailey Steven R. | Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof |
US20060167543A1 (en) | 1999-12-31 | 2006-07-27 | Bailey Steven R | Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof |
EP1248655A1 (en) | 2000-01-10 | 2002-10-16 | St. Jude Medical, Inc. | Biocompatible prosthetic tissue |
WO2001051104A1 (en) | 2000-01-10 | 2001-07-19 | St. Jude Medical, Inc. | Biocompatible prosthetic tissue |
US6471723B1 (en) | 2000-01-10 | 2002-10-29 | St. Jude Medical, Inc. | Biocompatible prosthetic tissue |
US6682559B2 (en) | 2000-01-27 | 2004-01-27 | 3F Therapeutics, Inc. | Prosthetic heart valve |
EP1251804B1 (en) | 2000-01-27 | 2008-07-02 | 3F Therapeutics, Inc | Prosthetic heart valve |
US7037333B2 (en) | 2000-01-27 | 2006-05-02 | 3F Therapeutics, Inc. | Prosthetic heart valve |
US6911043B2 (en) | 2000-01-27 | 2005-06-28 | 3F Therapeutics, Inc. | Prosthetic heart value |
US20040049262A1 (en) | 2000-01-31 | 2004-03-11 | Obermiller Joseph F. | Stent valves and uses of same |
US20050096736A1 (en) | 2000-01-31 | 2005-05-05 | Osse Francisco J. | Percutaneous heart valve devices |
WO2001054625A1 (en) | 2000-01-31 | 2001-08-02 | Cook Biotech Incorporated | Stent valves and uses of same |
EP1900343A2 (en) | 2000-01-31 | 2008-03-19 | Cook Biotech, Inc. | Stent valves and uses of same |
EP1255510B3 (en) | 2000-01-31 | 2009-03-04 | Cook Biotech, Inc. | Stent valves |
EP1255510B1 (en) | 2000-01-31 | 2007-04-25 | Cook Biotech, Inc. | Stent valves |
US6821297B2 (en) | 2000-02-02 | 2004-11-23 | Robert V. Snyders | Artificial heart valve, implantation instrument and method therefor |
EP1251803B1 (en) | 2000-02-02 | 2005-06-01 | Robert V. Snyders | Artificial heart valve |
US6540782B1 (en) | 2000-02-02 | 2003-04-01 | Robert V. Snyders | Artificial heart valve |
US20040210301A1 (en) | 2000-02-03 | 2004-10-21 | Obermiller Joseph F. | Implantable vascular device |
US20060142846A1 (en) | 2000-02-03 | 2006-06-29 | Dusan Pavcnik | Implantable vascular device |
EP1251805B1 (en) | 2000-02-03 | 2007-03-28 | Cook Incorporated | Implantable vascular device |
US20050143807A1 (en) | 2000-02-03 | 2005-06-30 | Dusan Pavcnik | Implantable vascular device comprising a bioabsorbable frame |
US20050267560A1 (en) | 2000-02-03 | 2005-12-01 | Cook Incorporated | Implantable bioabsorbable valve support frame |
US6391538B1 (en) | 2000-02-09 | 2002-05-21 | The Children's Hospital Of Philadelphia | Stabilization of implantable bioprosthetic tissue |
WO2001058503A1 (en) | 2000-02-09 | 2001-08-16 | The Children's Hospital Of Philadelphia | Stabilization of implantable bioprosthetic tissue |
EP1257305B1 (en) | 2000-02-09 | 2005-08-24 | The Children's Hospital Of Philadelphia | Stabilization of implantable bioprosthetic tissue |
US6824970B2 (en) | 2000-02-09 | 2004-11-30 | The Children's Hospital Of Philadelphia | Stabilization of implantable bioprosthetic tissue |
US6344044B1 (en) | 2000-02-11 | 2002-02-05 | Edwards Lifesciences Corp. | Apparatus and methods for delivery of intraluminal prosthesis |
US6808529B2 (en) | 2000-02-11 | 2004-10-26 | Edwards Lifesciences Corporation | Apparatus and methods for delivery of intraluminal prostheses |
EP1253875B1 (en) | 2000-02-11 | 2005-04-27 | Edwards Lifesciences Corporation | Apparatus for delivery of intraluminal prostheses |
US20030149478A1 (en) | 2000-02-28 | 2003-08-07 | Hans-Reiner Figulla | Device for fastening and anchoring cardiac valve prostheses |
DE10010073B4 (en) | 2000-02-28 | 2005-12-22 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anchoring for implantable heart valve prostheses |
DE20003874U1 (en) | 2000-02-28 | 2000-05-25 | Fraunhofer Ges Forschung | Device for fastening and anchoring heart valve prostheses |
EP1259193B1 (en) | 2000-02-28 | 2010-11-17 | JenaValve Technology Inc. | Anchoring system for implantable heart valve prostheses |
US20030149476A1 (en) | 2000-02-28 | 2003-08-07 | Christoph Damm | Anchoring system for implantable heart valve prostheses |
EP1259195B1 (en) | 2000-02-28 | 2008-10-15 | JenaValve Technology Inc. | Device for fastening and anchoring cardiac valve prostheses |
EP1994913A2 (en) | 2000-02-28 | 2008-11-26 | JenaValve Technology Inc. | Device for fixing and anchoring heart valve prosthetics |
DE10010074B4 (en) | 2000-02-28 | 2005-04-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Device for fastening and anchoring heart valve prostheses |
WO2001062189A1 (en) | 2000-02-28 | 2001-08-30 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Device for fastening and anchoring cardiac valve prostheses |
US7198646B2 (en) | 2000-02-28 | 2007-04-03 | Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V. | Device for fastening and anchoring cardiac valve prostheses |
WO2001064137A1 (en) | 2000-02-28 | 2001-09-07 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anchoring system for implantable heart valve prostheses |
JP2003523262A (en) | 2000-02-28 | 2003-08-05 | フラウンホーファー−ゲゼルシャフト ツール フエルデルング デア アンゲヴァンテン フォルシュング エー.ファオ. | Device for fastening and locking a prosthetic valve of the heart |
DE10010073A1 (en) | 2000-02-28 | 2001-09-27 | Fraunhofer Ges Forschung | Tie piece for heart valve prosthesis consists of hooked elements, and extra hooked elements, fixed by arms or base pieces |
US20070005129A1 (en) | 2000-02-28 | 2007-01-04 | Christoph Damm | Anchoring system for implantable heart valve prostheses |
DE10010074A1 (en) | 2000-02-28 | 2001-10-18 | Fraunhofer Ges Forschung | Device for fastening and anchoring heart valve prostheses |
JP2003524504A (en) | 2000-02-28 | 2003-08-19 | フラウンホーファー−ゲゼルシャフト ツール フエルデルング デア アンゲヴァンテン フォルシュング エー.ファオ. | Implantable artificial heart valve fixation system |
US20040186565A1 (en) | 2000-04-06 | 2004-09-23 | Stefan Schreck | Minimally-invasive heart valves with wireforms |
US6454799B1 (en) | 2000-04-06 | 2002-09-24 | Edwards Lifesciences Corporation | Minimally-invasive heart valves and methods of use |
US6767362B2 (en) | 2000-04-06 | 2004-07-27 | Edwards Lifesciences Corporation | Minimally-invasive heart valves and methods of use |
US20020198594A1 (en) | 2000-04-06 | 2002-12-26 | Stefan Schreck | Minimally-invasive heart valves and methods of use |
US7381218B2 (en) | 2000-04-06 | 2008-06-03 | Edwards Lifesciences Corporation | System and method for implanting a two-part prosthetic heart valve |
US20050096726A1 (en) | 2000-05-30 | 2005-05-05 | Jacques Sequin | Noncylindrical stent deployment system for treating vascular bifurcations |
US20030139803A1 (en) | 2000-05-30 | 2003-07-24 | Jacques Sequin | Method of stenting a vessel with stent lumenal diameter increasing distally |
US20030040792A1 (en) | 2000-09-12 | 2003-02-27 | Shlomo Gabbay | Heart valve prosthesis and sutureless implantation of a heart valve prosthesis |
US20020032481A1 (en) | 2000-09-12 | 2002-03-14 | Shlomo Gabbay | Heart valve prosthesis and sutureless implantation of a heart valve prosthesis |
WO2002036048A1 (en) | 2000-10-31 | 2002-05-10 | Jacques Seguin | Tubular support for setting, by percutaneous route, a substitution cusp |
US7014655B2 (en) | 2000-12-06 | 2006-03-21 | Rainer Frey | Method for conserving biological prostheses, conserved biological prostheses and conserving solutions |
EP1347785B1 (en) | 2000-12-06 | 2004-07-14 | Frey, Rainer | Method for conserving biological protheses, conserved biological protheses and conserving solutions |
WO2002058745A1 (en) | 2000-12-06 | 2002-08-01 | Frey, Rainer | Method for conserving biological protheses, conserved biological protheses and conserving solutions |
US6872226B2 (en) | 2001-01-29 | 2005-03-29 | 3F Therapeutics, Inc. | Method of cutting material for use in implantable medical device |
US20040186558A1 (en) | 2001-02-05 | 2004-09-23 | Cook Incorporated | Implantable vascular device |
US20080097586A1 (en) | 2001-02-05 | 2008-04-24 | Dusan Pavcnik | Implantable vascular device |
US20070162103A1 (en) | 2001-02-05 | 2007-07-12 | Cook Incorporated | Implantable device with remodelable material and covering material |
US20030055495A1 (en) | 2001-03-23 | 2003-03-20 | Pease Matthew L. | Rolled minimally-invasive heart valves and methods of manufacture |
US7078163B2 (en) | 2001-03-30 | 2006-07-18 | Medtronic, Inc. | Process for reducing mineralization of tissue used in transplantation |
DE10121210A1 (en) | 2001-04-30 | 2002-11-14 | Universitaetsklinikum Freiburg | Replacement heart valve, comprises an anchoring element, and has a starting volume which is opened up to the normal volume using a catheter |
US6790230B2 (en) | 2001-04-30 | 2004-09-14 | Universitatsklinikum Freiburg | Vascular implant |
US20020193871A1 (en) | 2001-04-30 | 2002-12-19 | Universitatsklinikum Freiburg | Vascular implant |
WO2002100301A1 (en) | 2001-06-13 | 2002-12-19 | Aortech Europe Limited | Heat valve prosthesis and method of manufacture |
EP1395208B1 (en) | 2001-06-14 | 2007-01-17 | Cemvac System Aktiebolag | Method and device for preparation of bone cement |
WO2002102286A1 (en) | 2001-06-14 | 2002-12-27 | Cemvac System Ab | Method and device for preparation of bone cement |
US20080215143A1 (en) | 2001-07-04 | 2008-09-04 | Jacques Seguin | Assembly for placing a prosthetic valve in a duct in the body |
US20050043790A1 (en) | 2001-07-04 | 2005-02-24 | Jacques Seguin | Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body |
WO2003003949A2 (en) | 2001-07-04 | 2003-01-16 | Jacques Seguin | Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body |
US7252682B2 (en) | 2001-07-04 | 2007-08-07 | Corevalve, S.A. | Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body |
EP1401359B1 (en) | 2001-07-04 | 2009-08-26 | CoreValve, Inc. | Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body |
WO2003007795A2 (en) | 2001-07-16 | 2003-01-30 | Edwards Lifesciences Corporation | Tissue engineered heart valve |
EP1406561A4 (en) | 2001-07-16 | 2008-03-12 | Edwards Lifesciences Corp | Tissue engineered heart valve |
US20030027332A1 (en) | 2001-07-16 | 2003-02-06 | Edwards Lifesciences Corporation | Tissue engineered heart valve |
US20050119728A1 (en) | 2001-07-19 | 2005-06-02 | The Cleveland Clinic Foundation | Method for fixing tissue |
EP1408882B1 (en) | 2001-07-26 | 2009-02-11 | 3F Therapeutics, Inc | Method of cutting material for use in implantable medical device |
US20050098547A1 (en) | 2001-07-26 | 2005-05-12 | Cali Douglas S. | Method of cutting material for use in implantable medical device |
WO2003009785A1 (en) | 2001-07-26 | 2003-02-06 | 3F Therapeutics, Inc. | Method of cutting material for use in implantable medical device |
WO2003011195A2 (en) | 2001-07-31 | 2003-02-13 | Corevalve | Assembly for setting a valve prosthesis in a corporeal duct |
US20050033398A1 (en) | 2001-07-31 | 2005-02-10 | Jacques Seguin | Assembly for setting a valve prosthesis in a corporeal duct |
EP1281375A2 (en) | 2001-08-03 | 2003-02-05 | Philipp Bonhoeffer | Implantation device and method for an endoprosthesis |
CA2436258A1 (en) | 2001-08-03 | 2005-01-30 | Philipp Bonhoeffer | Implant implantation unit and procedure for implanting the unit |
US20030036791A1 (en) | 2001-08-03 | 2003-02-20 | Bonhoeffer Philipp | Implant implantation unit and procedure for implanting the unit |
FR2828263A1 (en) | 2001-08-03 | 2003-02-07 | Philipp Bonhoeffer | IMPLANT IMPLANTATION DEVICE AND DEVICE IMPLANTATION METHOD |
US20050009000A1 (en) | 2001-08-06 | 2005-01-13 | Wilhelm Peter Lamm | Method for the devitalisation of natural organs and/or for the preparation of extracellular matrices for tissue engineering |
EP1414295A2 (en) | 2001-08-06 | 2004-05-06 | Peter Lamm | Method for the devitalisation of natural organs and/or for the preparation of extracellular matrices for tissue engineering |
WO2003013239A3 (en) | 2001-08-06 | 2003-10-02 | Peter Lamm | Method for the devitalisation of natural organs and/or for the preparation of extracellular matrices for tissue engineering |
US20030050694A1 (en) | 2001-09-13 | 2003-03-13 | Jibin Yang | Methods and apparatuses for deploying minimally-invasive heart valves |
US6821211B2 (en) | 2001-09-14 | 2004-11-23 | Golftech | Sport swing analysis system |
US20030065386A1 (en) | 2001-09-28 | 2003-04-03 | Weadock Kevin Shaun | Radially expandable endoprosthesis device with two-stage deployment |
WO2003028592A1 (en) | 2001-09-28 | 2003-04-10 | Ethicon, Inc. | Radially expandable endoprosthesis device with two-stage deployment |
EP1435879A4 (en) | 2001-09-28 | 2006-08-23 | Ethicon Inc | Radially expandable endoprosthesis device with two-stage deployment |
WO2003047468A1 (en) | 2001-10-11 | 2003-06-12 | Percutaneous Valve Technologies | Implantable prosthetic valve |
US7393360B2 (en) | 2001-10-11 | 2008-07-01 | Edwards Lifesciences Pvt, Inc. | Implantable prosthetic valve |
US20040039436A1 (en) | 2001-10-11 | 2004-02-26 | Benjamin Spenser | Implantable prosthetic valve |
US6730118B2 (en) | 2001-10-11 | 2004-05-04 | Percutaneous Valve Technologies, Inc. | Implantable prosthetic valve |
EP1441672B1 (en) | 2001-10-11 | 2011-09-14 | Edwards Lifesciences PVT, Inc. | Implantable prosthetic valve |
US20080004688A1 (en) | 2001-10-11 | 2008-01-03 | Benjamin Spenser | Implantable prosthetic valve |
US20030153974A1 (en) | 2001-10-11 | 2003-08-14 | Benjamin Spenser | Implantable prosthetic valve |
US20030114913A1 (en) | 2001-10-11 | 2003-06-19 | Benjamin Spenser | Implantable prosthetic valve |
US6893460B2 (en) | 2001-10-11 | 2005-05-17 | Percutaneous Valve Technologies Inc. | Implantable prosthetic valve |
US20050192665A1 (en) | 2001-10-11 | 2005-09-01 | Benjamin Spenser | Implantable prosthetic valve |
EP1435878B1 (en) | 2001-10-17 | 2008-04-02 | Boston Scientific Limited | System for fixation of endoluminal devices |
US20050143804A1 (en) | 2001-10-17 | 2005-06-30 | Haverkost Patrick A. | Method and system for fixation of endoluminal devices |
US20050113910A1 (en) | 2002-01-04 | 2005-05-26 | David Paniagua | Percutaneously implantable replacement heart valve device and method of making same |
EP1494616A4 (en) | 2002-03-21 | 2006-07-12 | Providence Health Sys Oregon | Bioprosthesis and method for suturelessly making same |
WO2003079928A2 (en) | 2002-03-21 | 2003-10-02 | Providence Health System-Oregon | Bioprosthesis and method for suturelessly making same |
US7163556B2 (en) | 2002-03-21 | 2007-01-16 | Providence Health System - Oregon | Bioprosthesis and method for suturelessly making same |
US7322932B2 (en) | 2002-03-21 | 2008-01-29 | Providence Health System - Oregon | Method for suturelessly attaching a biomaterial to an implantable bioprosthesis frame |
US7141064B2 (en) | 2002-05-08 | 2006-11-28 | Edwards Lifesciences Corporation | Compressed tissue for heart valve leaflets |
WO2003096935A1 (en) | 2002-05-16 | 2003-11-27 | Cook Incorporated | Flexible barb for anchoring a prosthesis |
US20040117004A1 (en) | 2002-05-16 | 2004-06-17 | Osborne Thomas A. | Stent and method of forming a stent with integral barbs |
US20030236570A1 (en) | 2002-05-16 | 2003-12-25 | Cook Incorporated | Flexible barb for anchoring a prosthesis |
US20080033534A1 (en) | 2002-05-16 | 2008-02-07 | Cook Incorporated | Flexible Barb for Anchoring a Prosthesis |
US7081132B2 (en) | 2002-05-16 | 2006-07-25 | Cook Incorporated | Flexible barb for anchoring a prosthesis |
US7050276B2 (en) | 2002-06-13 | 2006-05-23 | Alps Electric Co., Ltd. | GMR magnetic sensing element having an antiferromagnetic layer extending beyond the track width and method for making the same |
WO2004028399A2 (en) | 2002-06-28 | 2004-04-08 | Cook Incorporated | Thoracic deployment device |
EP1519697B1 (en) | 2002-07-05 | 2015-11-18 | C.R. Bard, Inc. | Stent delivery system |
US20040006380A1 (en) | 2002-07-05 | 2004-01-08 | Buck Jerrick C. | Stent delivery system |
WO2004004597A2 (en) | 2002-07-05 | 2004-01-15 | Edwards Lifesciences Ag | Stent delivery system |
US20060246584A1 (en) | 2002-08-01 | 2006-11-02 | Bruno Covelli | In-vitro method for the production of a homologous stented tissue-engineered heart valve |
EP1499366B1 (en) | 2002-08-01 | 2007-07-25 | Universität Zürich | In-vitro method for the production of a homologous stented tissue-engineered heart valve |
DE10301026A1 (en) | 2002-08-13 | 2004-02-26 | Markus Dr.med. Dr.disc.pol. Ferrari | Stent to be used for percutaneous insertion of artificial heart valve, comprising hook-shaped elements for exact positioning |
EP1469797B1 (en) | 2002-08-13 | 2005-11-02 | Hans-Reiner Figulla | Device for the implantation and fixing of heart valve prostheses |
WO2004019825A1 (en) | 2002-08-13 | 2004-03-11 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Device for the implantation and fixing of heart valve prostheses |
WO2004016200A1 (en) | 2002-08-15 | 2004-02-26 | Cook Incorporated | Implantable vascular device |
WO2004016201A2 (en) | 2002-08-15 | 2004-02-26 | Cook Incorporated | Stent and method of forming a stent with integral barbs |
US20040073289A1 (en) | 2002-08-23 | 2004-04-15 | William A. Cook Australia Pty. Ltd. | Asymmetric stent graft attachment |
US20040078950A1 (en) | 2002-09-20 | 2004-04-29 | Stefan Schreck | Continuous heart valve support frame and method of manufacture |
EP1539047A2 (en) | 2002-09-20 | 2005-06-15 | Edwards Lifesciences Corporation | Continuous heart valve support frame and method of manufacture |
WO2004026173A2 (en) | 2002-09-20 | 2004-04-01 | Edwards Lifesciences Corporation | Continuous heart valve support frame and method of manufacture |
US7137184B2 (en) | 2002-09-20 | 2006-11-21 | Edwards Lifesciences Corporation | Continuous heart valve support frame and method of manufacture |
US7318278B2 (en) | 2002-09-20 | 2008-01-15 | Edwards Lifesciences Corporation | Method of manufacture of a heart valve support frame |
US20050150775A1 (en) | 2002-09-20 | 2005-07-14 | Xiangyang Zhang | Method of manufacture of a heart valve support frame |
US20070173932A1 (en) | 2002-09-23 | 2007-07-26 | 3F Therapeutics, Inc. | Prosthetic mitral valve |
US20040117009A1 (en) | 2002-09-23 | 2004-06-17 | Cali Douglas S. | Prosthetic mitral valve |
WO2004026117A2 (en) | 2002-09-23 | 2004-04-01 | 3F Therapeutics, Inc. | Prosthetic mitral valve |
EP1551274B1 (en) | 2002-09-23 | 2014-12-24 | Medtronic 3F Therapeutics, Inc. | Prosthetic mitral valve |
US20070032856A1 (en) | 2002-09-30 | 2007-02-08 | Advanced Cardiovascular Systems, Inc. | Drug eluting stent |
EP1560542A1 (en) | 2002-11-11 | 2005-08-10 | Devax, Inc. | Endoprosthesis deployment system for treating vascular bifurcations |
WO2004043301A1 (en) | 2002-11-11 | 2004-05-27 | Devax, Inc. | Endoprosthesis deployment system for treating vascular bifurcations |
US20040102855A1 (en) | 2002-11-21 | 2004-05-27 | Scimed Life Systems, Inc. | Anti-reflux stent |
US20070005132A1 (en) | 2002-11-26 | 2007-01-04 | Simionescu Dan T | Tissue material and process for bioprosthesis |
US20040153145A1 (en) | 2002-11-26 | 2004-08-05 | Clemson University | Fixation method for bioprostheses |
US7189259B2 (en) | 2002-11-26 | 2007-03-13 | Clemson University | Tissue material and process for bioprosthesis |
US20050075776A1 (en) | 2002-11-28 | 2005-04-07 | Cho Young Shin | Shift control method and apparatus of an automatic transmission |
US20040193244A1 (en) | 2002-12-04 | 2004-09-30 | Cook Incorporated | Device and method for treating thoracic aorta |
US20060224183A1 (en) | 2003-01-21 | 2006-10-05 | Franz Freudenthal | Implantable device |
DE10302447A1 (en) | 2003-01-21 | 2004-07-29 | pfm Produkte für die Medizin AG | Implantable device for closing holes or making connections in human or animal bodies has a contractable supporting structure formed from a single wire-like element |
WO2004082528A2 (en) | 2003-03-17 | 2004-09-30 | Cook Incorporated | Vascular valve with removable support component |
WO2004082527A2 (en) | 2003-03-18 | 2004-09-30 | Edwards Lifesciences Corporation | Minimally-invasive heart valve with cusp positioners |
US7399315B2 (en) | 2003-03-18 | 2008-07-15 | Edwards Lifescience Corporation | Minimally-invasive heart valve with cusp positioners |
US20080269878A1 (en) | 2003-03-18 | 2008-10-30 | Edwards Lifesciences Corporation | Minimally-invasive heart valve with cusp positioners |
EP1603493B1 (en) | 2003-03-18 | 2011-12-28 | Edwards Lifesciences Corporation | Minimally-invasive heart valve with cusp positioners |
US20040186563A1 (en) | 2003-03-18 | 2004-09-23 | Lobbi Mario M. | Minimally-invasive heart valve with cusp positioners |
US20040210307A1 (en) | 2003-04-18 | 2004-10-21 | Alexander Khairkhahan | Percutaneous transcatheter heart valve replacement |
WO2004096100A1 (en) | 2003-04-24 | 2004-11-11 | Cook Incorporated | Artificial valve prosthesis with improved flow dynamics |
US20070038291A1 (en) | 2003-04-24 | 2007-02-15 | Cook Incorporated | Intralumenally-implantable frames |
US20040260389A1 (en) | 2003-04-24 | 2004-12-23 | Cook Incorporated | Artificial valve prosthesis with improved flow dynamics |
US20070021826A1 (en) | 2003-04-24 | 2007-01-25 | Cook Incorporated | Intralumenally implantable frames |
US20070260327A1 (en) | 2003-04-24 | 2007-11-08 | Case Brian C | Artificial Valve Prosthesis with Improved Flow Dynamics |
US20070100435A1 (en) | 2003-04-24 | 2007-05-03 | Cook Incorporated | Artificial prostheses with preferred geometries |
US20060259134A1 (en) | 2003-07-08 | 2006-11-16 | Ehud Schwammenthal | Implantable prosthetic devices particularly for transarterial delivery in the treatment of aortic stenosis, and methods of implanting such devices |
US20060149360A1 (en) | 2003-07-08 | 2006-07-06 | Ventor Technologies Ltd. | Fluid flow prosthetic device |
US20070185565A1 (en) | 2003-07-08 | 2007-08-09 | Ventor Technologies Ltd. | Fluid flow prosthetic device |
US7201772B2 (en) | 2003-07-08 | 2007-04-10 | Ventor Technologies, Ltd. | Fluid flow prosthetic device |
DE10335948B3 (en) | 2003-08-04 | 2005-02-03 | Qualimed Innovative Medizinprodukte Gmbh | Stent for medical applications comprises a tubular support structure made from joined ring segments and twisted by a thread with ends guided into the support structure via a deviating unit and coupled by a connector |
US20050049692A1 (en) | 2003-09-02 | 2005-03-03 | Numamoto Michael J. | Medical device for reduction of pressure effects of cardiac tricuspid valve regurgitation |
WO2005021063A2 (en) | 2003-09-02 | 2005-03-10 | 3F Therapeutics, Inc. | Medical device for reduction of pressure effects of cardiac tricuspid valve regurgitation |
EP1663070A2 (en) | 2003-09-02 | 2006-06-07 | 3F Therapeutics, Inc | Medical device for reduction of pressure effects of cardiac tricuspid valve regurgitation |
US20080275549A1 (en) | 2003-10-02 | 2008-11-06 | Edwards Lifesciences Pvt, Inc. | Implantable prosthetic valve with non-laminar flow |
WO2005034812A1 (en) | 2003-10-02 | 2005-04-21 | Edwards Lifesciences Corporation | Implantable prosthetic valve with non-laminar flow |
US20050075725A1 (en) | 2003-10-02 | 2005-04-07 | Rowe Stanton J. | Implantable prosthetic valve with non-laminar flow |
EP1667614A1 (en) | 2003-10-02 | 2006-06-14 | Edwards Lifesciences Corporation | Implantable prosthetic valve with non-laminar flow |
US20060259137A1 (en) | 2003-10-06 | 2006-11-16 | Jason Artof | Minimally invasive valve replacement system |
US20050119736A1 (en) | 2003-10-30 | 2005-06-02 | Peter Zilla | Bioprosthetic tissue preparation with synthetic hydrogels |
US20050096735A1 (en) | 2003-10-31 | 2005-05-05 | Hikmat Hojeibane | Implantable valvular prosthesis |
US20050222668A1 (en) | 2003-11-08 | 2005-10-06 | Schaeffer Darin G | Flareable branch vessel prosthesis and method |
US20070179592A1 (en) | 2003-11-08 | 2007-08-02 | Schaeffer Darin G | Branch vessel prosthesis with positional indicator system and method |
US20050149166A1 (en) | 2003-11-08 | 2005-07-07 | Schaeffer Darin G. | Branch vessel prosthesis with anchoring device and method |
US20050171597A1 (en) | 2003-11-08 | 2005-08-04 | Boatman Scott E. | Helical stent for branched vessel prosthesis |
US20060058864A1 (en) | 2003-11-08 | 2006-03-16 | Schaeffer Darin G | Balloon flareable branch vessel prosthesis and method |
US20050171598A1 (en) | 2003-11-08 | 2005-08-04 | Schaeffer Darin G. | Aorta and branch vessel stent grafts and method |
US20050137697A1 (en) | 2003-12-23 | 2005-06-23 | Amr Salahieh | Leaflet engagement elements and methods for use thereof |
US20050137688A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical, A Delaware Corporation | Repositionable heart valve and method |
US20050137687A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Heart valve anchor and method |
WO2005070343A1 (en) | 2003-12-23 | 2005-08-04 | Laboratoires Perouse | Kit which is intended to be implanted in a conduit |
US20050137689A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical, A Delware Corporation | Retrievable heart valve anchor and method |
US20050137690A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Low profile heart valve and delivery system |
US20050137702A1 (en) | 2003-12-23 | 2005-06-23 | Haug Ulrich R. | Methods and apparatus for endovascularly replacing a patient's heart valve |
EP1702247B1 (en) | 2003-12-23 | 2015-08-05 | Sadra Medical, Inc. | Repositionable heart valve |
US20050137698A1 (en) | 2003-12-23 | 2005-06-23 | Amr Salahieh | Leaflet engagement elements and methods for use thereof |
WO2005062980A2 (en) | 2003-12-23 | 2005-07-14 | Sadra Medical, Inc. | Repositionable heart valve |
WO2005063980A1 (en) | 2003-12-31 | 2005-07-14 | Toudai Tlo, Ltd. | METHOD OF ENZYMATICALLY CONSTRUCTING RNAi LIBRARY |
EP1734902A1 (en) | 2004-01-23 | 2006-12-27 | Edwards Lifesciences Corporation | Anatomically approximate prosthetic mitral heart valve |
WO2005072654A1 (en) | 2004-01-23 | 2005-08-11 | Edwards Lifesciences Corporation | Anatomically approximate prosthetic mitral heart valve |
US20060293745A1 (en) | 2004-01-23 | 2006-12-28 | Carpentier Alain F | Anatomically approximate prosthetic mitral heart valve |
US20050234546A1 (en) | 2004-02-05 | 2005-10-20 | Alan Nugent | Transcatheter delivery of a replacement heart valve |
US20050197695A1 (en) | 2004-03-03 | 2005-09-08 | Sorin Biomedica Cardio S.R.L. | Minimally-invasive cardiac-valve prosthesis |
US20060025857A1 (en) | 2004-04-23 | 2006-02-02 | Bjarne Bergheim | Implantable prosthetic valve |
US20060074485A1 (en) | 2004-05-17 | 2006-04-06 | Fidel Realyvasquez | Method and apparatus for percutaneous valve repair |
US20070123700A1 (en) | 2004-06-01 | 2007-05-31 | Yuichiro Ueda | Processes for removing cells and cell debris from tissue and tissue constructs used in transplantation and tissue reconstruction |
US20060047343A1 (en) | 2004-08-24 | 2006-03-02 | Oviatt Henry W | Anti-calcification treatments for heart valves and vascular grafts |
US20060074484A1 (en) | 2004-10-02 | 2006-04-06 | Huber Christoph H | Methods and devices for repair or replacement of heart valves or adjacent tissue without the need for full cardiopulmonary support |
EP1835948B1 (en) | 2004-12-24 | 2016-02-24 | Admedus Regen Pty Ltd. | An implantable biomaterial and a method of producing same |
WO2006066327A1 (en) | 2004-12-24 | 2006-06-29 | Celxcel Pty Ltd | An implantable biomaterial and a method of producing same |
US20060193885A1 (en) | 2004-12-24 | 2006-08-31 | Celxcel Pty Ltd | Implantable biomaterial and a method of producing same |
US20060155366A1 (en) | 2005-01-10 | 2006-07-13 | Laduca Robert | Apparatus and method for deploying an implantable device within the body |
CA2595233C (en) | 2005-01-20 | 2011-05-17 | Fraunhofer Gesellschaft Zur Forderung Der Angewandten Forschung E.V. | Catheter for the transvascular implantation of prosthetic heart valves |
GB2433700A (en) | 2005-01-20 | 2007-07-04 | Fraunhofer Ges Forschung | Catheter for the transvascular implantation of prosthetic heart valves |
US20090234443A1 (en) | 2005-01-20 | 2009-09-17 | Ottma Ruediger | Catheter for the Transvascular Implantation of Prosthetic Heart Valves |
CA2595233A1 (en) | 2005-01-20 | 2006-07-27 | Fraunhofer Gesellschaft Zur Forderung Der Angewandten Forschung E.V. | Catheter for the transvascular implantation of prosthetic heart valves |
WO2006076890A1 (en) | 2005-01-20 | 2006-07-27 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Catheter for the transvascular implantation of prosthetic heart valves |
US20060178740A1 (en) | 2005-02-10 | 2006-08-10 | Sorin Biomedica Cardio S.R.L. | Cardiac-valve prosthesis |
EP1690515A1 (en) | 2005-02-10 | 2006-08-16 | Sorin Biomedica Cardio S.R.L. | Cardiac-valve prosthesis |
US20070020248A1 (en) | 2005-03-01 | 2007-01-25 | Everaerts Frank J L | Process for biological tissue |
WO2006102063A2 (en) | 2005-03-19 | 2006-09-28 | Cook Biotech Incorporated | Prosthetic implants including ecm composite material |
US20060210597A1 (en) | 2005-03-19 | 2006-09-21 | Cook Biotech Incorporated | Prosthetic implants including ECM composite material |
EP1863545B1 (en) | 2005-03-19 | 2015-11-18 | Cook Biotech, Inc. | Prosthetic implants including ECM composite material |
WO2006108090A2 (en) | 2005-04-06 | 2006-10-12 | Edwards Lifesciences Corporation | Connecting band and stress absorbing frame for highly flexible heart valve |
US20060229718A1 (en) | 2005-04-06 | 2006-10-12 | Salvador Marquez | Stress absorbing flexible heart valve frame |
US7473275B2 (en) | 2005-04-06 | 2009-01-06 | Edwards Lifesciences Corporation | Stress absorbing flexible heart valve frame |
US20060229719A1 (en) | 2005-04-06 | 2006-10-12 | Salvador Marquez | Highly flexible heart valve connecting band |
EP1893132B1 (en) | 2005-05-13 | 2011-03-02 | Medtronic Corevalve LLC | Heart valve prothesis |
US20060259136A1 (en) | 2005-05-13 | 2006-11-16 | Corevalve Sa | Heart valve prosthesis and methods of manufacture and use |
WO2006124649A2 (en) | 2005-05-13 | 2006-11-23 | Corevalve, Inc. | Heart valve prothesis and methods of manufacture and use |
US20060265056A1 (en) | 2005-05-13 | 2006-11-23 | Corevalve, Inc. | Heart valve prosthesis and methods of manufacture and use |
WO2006127765A1 (en) | 2005-05-24 | 2006-11-30 | Corevalve, Inc. | A non-cylindrical prosthetic valve system for transluminal delivery |
WO2006127756A2 (en) | 2005-05-24 | 2006-11-30 | Edwards Lifesciences Corporation | Rapid deployment prosthetic heart valve |
US20060287719A1 (en) | 2005-05-24 | 2006-12-21 | Rowe Stanton J | Rapid deployment prosthetic heart valve |
US20060287717A1 (en) | 2005-05-24 | 2006-12-21 | Rowe Stanton J | Methods for rapid deployment of prosthetic heart valves |
US20060271161A1 (en) | 2005-05-26 | 2006-11-30 | Boston Scientific Scimed, Inc. | Selective treatment of stent side branch petals |
US7238200B2 (en) | 2005-06-03 | 2007-07-03 | Arbor Surgical Technologies, Inc. | Apparatus and methods for making leaflets and valve prostheses including such leaflets |
WO2006132948A1 (en) | 2005-06-03 | 2006-12-14 | Arbor Surgical Technologies, Inc. | Apparatus and methods for making leaflets and valve prostheses including such leaflets |
US20070203576A1 (en) | 2005-06-03 | 2007-08-30 | Arbor Surgical Technologies, Inc. | Apparatus and methods for making leaflets and valve prostheses including such leaflets |
EP1901681A1 (en) | 2005-06-03 | 2008-03-26 | Arbor Surgical Technologies, Inc. | Apparatus and methods for making leaflets and valve prostheses including such leaflets |
US20070005131A1 (en) | 2005-06-13 | 2007-01-04 | Taylor David M | Heart valve delivery system |
US20070123979A1 (en) | 2005-06-27 | 2007-05-31 | Patrick Perier | Apparatus, system, and method for treatment of posterior leaflet prolapse |
US20070027535A1 (en) | 2005-07-28 | 2007-02-01 | Cook Incorporated | Implantable thromboresistant valve |
US20070038295A1 (en) | 2005-08-12 | 2007-02-15 | Cook Incorporated | Artificial valve prosthesis having a ring frame |
US20070050014A1 (en) | 2005-08-31 | 2007-03-01 | Johnson Chad E | Implantable valve |
WO2007047488A2 (en) | 2005-10-18 | 2007-04-26 | Edwards Lifesciences Corporation | Heart valve delivery system with valve catheter |
US20070088431A1 (en) | 2005-10-18 | 2007-04-19 | Henry Bourang | Heart valve delivery system with valve catheter |
WO2007047945A2 (en) | 2005-10-21 | 2007-04-26 | Cook Incorporated | Artificial valve with center leaflet attachment |
US20070093887A1 (en) | 2005-10-21 | 2007-04-26 | Cook Incorporated | Artificial valve with center leaflet attachment |
AU2006308187A1 (en) | 2005-10-28 | 2007-05-03 | Jenavalve Technology Inc. | Device for implanting and fastening heart valve prostheses |
DE102005051849B4 (en) | 2005-10-28 | 2010-01-21 | JenaValve Technology Inc., Wilmington | Device for implantation and attachment of heart valve prostheses |
US8551160B2 (en) | 2005-10-28 | 2013-10-08 | Jenavalve Technology, Inc. | Device for the implantation and fixation of prosthetic valves |
US20070100440A1 (en) | 2005-10-28 | 2007-05-03 | Jen.Cardiotec Gmbh | Device for the implantation and fixation of prosthetic valves |
US20070142906A1 (en) | 2005-11-04 | 2007-06-21 | Jen. Cardiotec Gmbh | Self-expandable medical instrument for treating defects in a patient's heart |
WO2007051620A1 (en) | 2005-11-04 | 2007-05-10 | Jenavalve Technology Inc. | Self-expandable medical instrument for treatment of defects on a patient’s heart |
US20090222076A1 (en) | 2005-11-04 | 2009-09-03 | Jen. Cardiotec Gmbh | Self-Expandable Medical Instrument for Treating of Defects in a Patient's Heart |
CA2627555A1 (en) | 2005-11-04 | 2007-05-10 | Jenavalve Technology Inc. | Self-expandable medical instrument for treating defects in a patient's heart |
AU2006310681A1 (en) | 2005-11-04 | 2007-05-10 | Jenavalve Technology Inc. | Self-expandable medical instrument for treatment of defects on a patient's heart |
US20070112422A1 (en) | 2005-11-16 | 2007-05-17 | Mark Dehdashtian | Transapical heart valve delivery system and method |
WO2007059252A1 (en) | 2005-11-16 | 2007-05-24 | Edwards Lifesciences Corporation | Transapical heart valve delivery system and method |
US20070213813A1 (en) | 2005-12-22 | 2007-09-13 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
WO2007071436A2 (en) | 2005-12-22 | 2007-06-28 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
WO2007098232A2 (en) | 2006-02-21 | 2007-08-30 | Med Institute, Inc. | Split sheath deployment system |
US20070239271A1 (en) | 2006-04-10 | 2007-10-11 | Than Nguyen | Systems and methods for loading a prosthesis onto a minimally invasive delivery system |
WO2007120543A1 (en) | 2006-04-10 | 2007-10-25 | Corevalve, Inc. | Systems and methods for loading a prosthesis onto a minimally invasive delivery system |
US20070244551A1 (en) | 2006-04-14 | 2007-10-18 | Robert Stobie | Holders for prosthetic aortic heart valves |
US20070288087A1 (en) | 2006-05-30 | 2007-12-13 | Cook Incorporated | Artificial valve prosthesis |
EP1878407A1 (en) | 2006-07-12 | 2008-01-16 | Efstathios-Andreas Agathos | Human cardiac valve replacement with seal heart valve (aortic or pulmonary) |
US20080021546A1 (en) | 2006-07-18 | 2008-01-24 | Tim Patz | System for deploying balloon-expandable heart valves |
GB2440809A (en) | 2006-07-28 | 2008-02-13 | Geoffrey Douglas Tansley | Prosthetic heart valve with leaflets curved by residual stresses |
WO2008028569A1 (en) | 2006-09-07 | 2008-03-13 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
US20080065011A1 (en) | 2006-09-08 | 2008-03-13 | Philippe Marchand | Integrated heart valve delivery system |
US20080071369A1 (en) | 2006-09-19 | 2008-03-20 | Yosi Tuval | Valve fixation member having engagement arms |
US20080071366A1 (en) | 2006-09-19 | 2008-03-20 | Yosi Tuval | Axial-force fixation member for valve |
US20080071362A1 (en) | 2006-09-19 | 2008-03-20 | Yosi Tuval | Valve prosthesis implantation techniques |
US20080071363A1 (en) | 2006-09-19 | 2008-03-20 | Yosi Tuval | Valve prosthesis fixation techniques using sandwiching |
US20080071361A1 (en) | 2006-09-19 | 2008-03-20 | Yosi Tuval | Leaflet-sensitive valve fixation member |
US20080071368A1 (en) | 2006-09-19 | 2008-03-20 | Yosi Tuval | Sinus-engaging valve fixation member |
WO2008035337A2 (en) | 2006-09-19 | 2008-03-27 | Ventor Technologies, Ltd. | Fixation member for valve |
WO2008045949A3 (en) | 2006-10-10 | 2009-06-04 | Celonova Biosciences Inc | Bioprosthetic heart valve with polyphosphazene |
US20080086205A1 (en) | 2006-10-10 | 2008-04-10 | Celonova Biosciences, Inc. | Bioprosthetic Heart Valve With Polyphosphazene |
US20080102439A1 (en) | 2006-10-27 | 2008-05-01 | Bin Tian | Biological tissue for surgical implantation |
WO2008070797A2 (en) | 2006-12-06 | 2008-06-12 | Medtronic Corevalve, Inc. | System and method for transapical delivery of an annulus anchored self-expanding valve |
US20080140189A1 (en) | 2006-12-06 | 2008-06-12 | Corevalve, Inc. | System and method for transapical delivery of an annulus anchored self-expanding valve |
WO2008079962A1 (en) | 2006-12-22 | 2008-07-03 | Edwards Lifesciences Corporation | Implantable prosthetic valve assembly and method for making the same |
US20080154355A1 (en) | 2006-12-22 | 2008-06-26 | Netanel Benichou | Implantable prosthetic valve assembly and method of making the same |
US20080200977A1 (en) | 2007-02-15 | 2008-08-21 | Cook Incorporated | Artificial Valve Prostheses with a Free Leaflet Portion |
WO2008101083A2 (en) | 2007-02-15 | 2008-08-21 | Cook Incorporated | Artificial valve prostheses with a free leaflet portion |
US20080255661A1 (en) | 2007-04-13 | 2008-10-16 | Helmut Straubinger | Medical device for treating a heart valve insufficiency or stenosis |
WO2008125153A1 (en) | 2007-04-13 | 2008-10-23 | Jenavalve Technology Inc. | Medical device for treating a heart valve insufficiency or stenosis |
EP1980220A1 (en) | 2007-04-13 | 2008-10-15 | JenaValve Technology GmbH | Medical device for treating a heart valve insufficiency or stenosis |
US20110015616A1 (en) | 2007-04-13 | 2011-01-20 | Helmut Straubinger | Handle for manipulating a catheter tip, catheter system and medical insertion system for inserting a self-expandable heart valve stent |
US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US7914575B2 (en) | 2007-04-13 | 2011-03-29 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
DE202007005491U1 (en) | 2007-04-13 | 2007-06-14 | Jenavalve Technology Gmbh | Medical device for treating aortic valve insufficiency of patient, has self-expandable endoprosthesis for positioning and fixing heart valve implant in arota of patient, and retaining segment with brackets for receiving implant |
US20100174362A1 (en) | 2007-04-13 | 2010-07-08 | Helmut Straubinger | Medical Device for Treating A Heart Valve Insufficiency or Stenosis |
US20110238159A1 (en) | 2007-04-13 | 2011-09-29 | Volker Guyenot | Medical device for treating a heart valve insufficiency |
US20080255660A1 (en) | 2007-04-13 | 2008-10-16 | Volker Guyenot | Medical device for treating a heart valve insufficiency |
WO2008138584A1 (en) | 2007-05-15 | 2008-11-20 | Jenavalve Technology Inc. | Handle for manipulating a catheter tip, catheter system and medical insertion system for inserting a self-expandable heart valve stent |
WO2008150529A1 (en) | 2007-06-04 | 2008-12-11 | St. Jude Medical, Inc. | Prosthetic heart valves |
US20110106244A1 (en) | 2008-01-25 | 2011-05-05 | Markus Ferrari | Medical apparatus for the therapeutic treatment of an insufficient cardiac valve |
US20130079869A1 (en) | 2008-02-26 | 2013-03-28 | Helmut Straubinger | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US8398704B2 (en) | 2008-02-26 | 2013-03-19 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US20090216310A1 (en) | 2008-02-26 | 2009-08-27 | Helmut Straubinger | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US8465540B2 (en) | 2008-02-26 | 2013-06-18 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis |
US20130253635A1 (en) | 2008-02-26 | 2013-09-26 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US20090216313A1 (en) | 2008-02-26 | 2009-08-27 | Helmut Straubinger | Stent for the positioning and anchoring of a valvular prosthesis |
US20100249917A1 (en) | 2009-03-30 | 2010-09-30 | Ji Zhang | Methods for Delivery of a Sutureless Pulmonary or Mitral Valve |
US20100249916A1 (en) | 2009-03-30 | 2010-09-30 | Ji Zhang | Methods and devices for transapical delivery of a sutureless valve prosthesis |
US20100249918A1 (en) | 2009-03-30 | 2010-09-30 | Ji Zhang | Devices and methods for delivery of aortic and mitral valve prostheses |
US20100249915A1 (en) | 2009-03-30 | 2010-09-30 | Ji Zhang | Valve prosthesis with movably attached claspers with apex |
US8468667B2 (en) | 2009-05-15 | 2013-06-25 | Jenavalve Technology, Inc. | Device for compressing a stent |
US20100292779A1 (en) | 2009-05-15 | 2010-11-18 | Helmut Straubinger | Device for compressing a stent and a system as well as a method for loading a stent into a medical delivery system |
US20130178930A1 (en) | 2010-05-20 | 2013-07-11 | Helmut Straubinger | Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect |
US20110288626A1 (en) | 2010-05-20 | 2011-11-24 | Helmut Straubinger | Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect |
US20110295363A1 (en) | 2010-05-25 | 2011-12-01 | Girard Michael J | Prosthetic Heart Valve And Transcatheter Delivered Endoprosthesis Comprising A Prosthetic Heart Valve And A Stent |
Non-Patent Citations (13)
Title |
---|
Aortenklappenbioprothese erfolgreich in der Entwicklung, May 16, 2003 (1 page). |
English translation of Aortenklappenbioprotheseerfolgreich in der Entwicklung (2 pages). |
English translation of DE 19 546 692 A1 (4 pages). |
English translation of EP 1 469 797 B1 (16 pages). |
File history for German Patent DE 195 46 692 filed Dec. 14, 1995 and patented Jul. 11, 2002. |
Gummert, J.F. et al., "Cardiac Surgery in Germany During 2006: A Report on Behalf of the German Society for Thoracic and Cardiovascular Surgery," Thorac. Cardiov. Surg., vol. 55, pp. 343-350 (2007) (8 pages). |
Gummert, J.F. et al., "Cardiac Surgery in Germany During 2007: A Report on Behalf of the German Society for Thoracic and Cardiovascular Surgery," Thorac. Cardiov. Surg., vol. 56, pp. 328-336 (2008) (9 pages). |
Huber, Christoph H., et al. "Direct Access Valve Replacement (DAVR)-are we entering a new era in cardiac surgery?" Eur. J. Cardio-Thoracic Surgery, vol. 29, pp. 380-385 (2006) (6 pages). |
International Search Report for PCT/EP2006/010023. |
Klein, Allan L. et al., "Age-related Prevalence of Valvular Regurgitation in Normal Subjects: A Comprehensive Color Flow Examination of 118 Volunteers," J. Am. Soc. Echocardiography, vol. 3, No. 1, pp. 54-63 (1990) (10 pages). |
Liang, Ma, et al., "Double-crowned valved stents for off-pump mitral valve replacement," Eur. J. Cardio-Thoracic Surgery, vol. 28, pp. 194-198 (2005) (5 pages). |
Screen shots from http://www.fraunhofer.de/presse/filme/2006/index.jsp, 2006 (2 pages). |
Translation of Aortenklappenbioprothese erfolgreich in der Entwicklung (2 pages). |
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