US4950245A - Multiple fluid cartridge and pump - Google Patents

Multiple fluid cartridge and pump Download PDF

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Publication number
US4950245A
US4950245A US07/216,512 US21651288A US4950245A US 4950245 A US4950245 A US 4950245A US 21651288 A US21651288 A US 21651288A US 4950245 A US4950245 A US 4950245A
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Prior art keywords
cartridge
pump
fluid
housing
linear
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US07/216,512
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Eric W. Brown
Charles Kienholz
Steve Busak
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I Flow Corp
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I Flow Corp
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Priority to US07/216,512 priority Critical patent/US4950245A/en
Assigned to I-FLOW CORPORATION reassignment I-FLOW CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: BROWN, ERIC W., BUSAK, STEVE, KIENHOLZ, CHARLES
Priority to US07/301,628 priority patent/US5011378A/en
Priority to US07/351,981 priority patent/US5131816A/en
Priority to EP19890111139 priority patent/EP0354324A3/en
Priority to JP1174111A priority patent/JPH0482564A/en
Application granted granted Critical
Publication of US4950245A publication Critical patent/US4950245A/en
Assigned to SILICON VALLEY BANK reassignment SILICON VALLEY BANK SECURITY INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: I-FLOW CORPORATION
Assigned to SILICON VALLEY BANK reassignment SILICON VALLEY BANK SECURITY INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: I-FLOW CORPORATION
Anticipated expiration legal-status Critical
Assigned to I-FLOW CORPORATION reassignment I-FLOW CORPORATION RELEASE Assignors: SILICON VALLEY BANK
Assigned to I-FLOW CORPORATION reassignment I-FLOW CORPORATION RELEASE BY SECURED PARTY (SEE DOCUMENT FOR DETAILS). Assignors: SILICON VALLEY BANK
Assigned to I-FLOW CORPORATION reassignment I-FLOW CORPORATION RELEASE Assignors: SILICON VALLEY BANK
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14228—Pumping with an aspiration and an expulsion action with linear peristaltic action, i.e. comprising at least three pressurising members or a helical member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A61M5/16827—Flow controllers controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/12—Pressure infusion

Definitions

  • This invention relates to a multiple fluid cartridge which is insertable into a programmable infusion pump.
  • An object of the present invention is to provide in a single ambulatory housing, separately controlled pumping mechanisms for each of a plurality of fluid sources. It is a still further object of the present invention to provide multiple fluid source cartridges which are attachable to a pump of the present invention.
  • the present invention is directed to an infusion pump system including a fluid source cartridge which is attachable to a pump housing.
  • the pump housing has a plurality of linear peristaltic pumps.
  • Each fluid source in the cartridge has a linear fluid conduit which aligns with a peristaltic pump when the cartridge is inserted into the housing.
  • the pumping of fluid from any of the fluid sources in the cartridge is controlled by the source's respective peristaltic pump.
  • the infusion pump housing may be advantageously provided with a programmable controller to permit individual control over each of the peristaltic pumps. This permits operating the pumps sequentially or concurrently and at any selected pumping rate.
  • the multiple fluid source cartridge may be further provided with a module containing a plurality of plunger members. Each module overlies a linear conduit and the plunger members are alternately moved by the fingers of the peristaltic pump in the pump housing to cause fluid to be pumped from its respective fluid source.
  • the same cartridge may be used for any number from one to four fluid sources, it being only necessary to provide the appropriate number of plunger modules in the cartridge.
  • FIG. 1 is a perspective view of the pump and cartridge of the present invention.
  • FIG. 2 is a side view illustrating how a cartridge attaches to a pump according to the present invention.
  • FIG. 3 is a plan view of a cartridge of the present invention with the top wall of the cartridge housing removed.
  • FIG. 4 is a bottom plan view of the pump of the present invention without a cartridge in place.
  • FIG. 5 is an end view of the pump of FIG. 4.
  • FIG. 6 is a side cross-sectional view of the pump and cartridge of the present invention.
  • a pump housing 10 is provided for pumping fluid from a multiple fluid cartridge 20.
  • the pump housing 10 is provided with a liquid crystal display 12, a keyboard 14 and as shown in FIG. 5, programming jacks 16.
  • the underside of the pump housing 10 forms a cavity for receiving the cartridge 20.
  • the cavity extends through one end of the pump housing 10. Just inside the open end of the housing, there are two cartridge retaining holes 18 for engaging retaining knobs 34 on the cartridge.
  • the cartridge 20 houses one or more fluid sources 44.
  • the cartridge 20 further has space for four plunger modules 24.
  • Each plunger module 24 has three plunger members which are used for pumping fluid through a linear fluid conduit positioned directly beneath the module 24.
  • the inside end of the fluid conduit connects to one of the fluid sources in the body of the cartridge 20.
  • a connector 26 serves as the output port for delivering fluid into an output lumen.
  • FIG. 1 all four lumens are being used by the cartridge 20.
  • the lumens are fused together to form a multi-lumen tube for outputting the fluid to a connector for making connection with an implanted catheter, for example.
  • the multi-lumen output tube may be connected to any of a variety of a multi-lumen connectors. Three possibilities are shown in FIG. 1.
  • a needle connector 28 may be used in which each lumen is connected to a hollow injection needle.
  • the needle connector may be inserted through a silicone block to make connection with a connector for a multi-lumen catheter.
  • Another option is a multi-lumen connector such as that described in co-pending U.S. patent application Ser. No. 178,673 filed on Apr. 7, 1988, owned by the same assignee as the present invention.
  • the disclosure of said application is hereby incorporated by reference herein.
  • a third possibility for the output tube is to connect each lumen separately to a luer connector 32 so that individual connections can be made to four separate catheter lines.
  • the cartridge 20 is provided with a retaining knob 34 on two opposite sides near its front end.
  • the retaining knob 34 is preferably a linear flange cocked at an angle with respect to the bottom of the cartridge.
  • the knob 34 is cocked at approximately a 45 degree angle with respect to the bottom of the cartridge, one end of the knob pointing towards the top of the cartridge and the other end of the knob pointing towards the front end of the cartridge. This permits the end of the knob 34 which points towards the top of the cartridge to be inserted into the retaining hole 18 in the pump housing 10 while the rear of the cartridge 20 hangs below the pump as shown in FIG. 2.
  • the retaining hole 18 has an entrance opening 19 at the front of the housing. Once the entire knob 34 has been inserted through the opening 19 into the retaining hole 18, the cartridge 20 can be swung upwards to fully engage the pump housing 10.
  • a lock 36 is provided for engaging a tab 22 on the rear end of the cartridge.
  • the lock 36 according to the presently preferred embodiment is provided with a beveled edge 38 and a retaining edge 39.
  • a spring 40 urges the lock 36 to hold the cartridge in place.
  • the cartridge tab 22 slides along the beveled edge 38 and pushes the lock back against the action of the spring 40.
  • the spring forces the lock back beneath the cartridge tab 22 so that the tab 22 is held up on top of the retaining edge 39.
  • the lock 36 prevents the cartridge 20 from falling out of the pump housing.
  • the retaining knob 34 which entered the retaining holes 18 in a horizontal position are at an angle when the cartridge is fully inserted. Thus, the retaining knobs 34 cannot slide out of the retaining holes 18.
  • the cartridge lock 36 of the pump housing is further shown in FIG. 4, where it can be seen that the lock 36 swivels about an axis 41.
  • the spring 40 urges the engaging end of the lock 36 against the cartridge 20.
  • a cartridge can be released from the pump housing 10 by pushing against the other end of the lock 36 which forms a button 42 through an opening in the pump housing.
  • button 42 When button 42 is pressed, the lock 36 swings away from the cartridge 20, permitting the tab 22 to disengage from the retaining edge 39 of the lock.
  • the back end of the cartridge can fall out of the pump housing and when the retaining knobs 34 are in horizontal position with respect to the pump housing, they may be slid out through the openings 19.
  • FIG. 3 reveals the fluid sources stored within the cartridge 20.
  • Each fluid source 44 is provided with a linear fluid conduit 45 beneath a plunger module 24.
  • the fluid sources 44 are flexible pouches.
  • the presently suggested procedure for using the cartridges 20 is to provide them with empty pouches.
  • the desired fluid is injected into the connector port 26, using a syringe or other conventional means.
  • the connector port 26 is attached to the output tube.
  • the cartridge may be inserted into the pump housing 10 and a purge cycle may be run on each of the fluid sources to pump out all of the air which may have gotten into the pouch or conduit line. After purging the air, the cartridge 20 is ready for use in an infusion.
  • the pump of the present invention is provided with a plurality, four in this case, of linear peristaltic pumps.
  • Linear peristaltic pumps are well known and any conventional design may be used to accomplish the objectives of the present invention.
  • the pump of the preferred embodiment is a three finger pump, called such because of the three cams which are repeatedly lowered and raised to provide the desired pumping action.
  • Each pump thus activates three cam followers, including an output cam follower 46 and a pump cam follower 48 and an input cam follower 50.
  • Power for the pumps is provided by a battery which may be loaded into a cavity behind a battery cover 52 alongside the peristaltic pumps within the housing 10.
  • Each pump is provided with its own motor 54 which turns a cam shaft 56.
  • the cam shaft 56 is provided with a timing disk 58.
  • the timing disk is read by a timing circuit on a printed circuit board 60.
  • Signal feedback from the timing circuit on the printed circuit board 60 can be provided to control the speed of the motor 54 and thus control the rate of fluid infusion from any of the fluid sources.
  • a spring 62 is located about each of the cam followers to urge the cam follower into a retracted position.
  • Each plunger module 24 includes an output valve 63, a pump 64 and an input valve 66.
  • the linear fluid conduit 45 beneath each plunger assembly 24 is provided through a silicone block 68.
  • a silicone block 68 is provided in each of the plunger modules.
  • a connector 70 at the end of the fluid conduit within the cartridge 20 is used for attaching the conduit to its respective fluid source 44.
  • Each linear conduit 45 has an enlarged portion beneath the pump plunger 64. This enlarged portion of the conduit is called a pump tube 74.
  • Pumping is performed as follows. With the pump plunger 64 and the input valve 66 retracted, the output cam follower 46 is lowered against the output valve 63 to close off the fluid conduits. This permits the pump tube 74 to fill with fluid. Next, the input valve 66 is lowered by the input cam follower 50 to close off the pump tube 74 and prevent fluid from flowing back into the fluid source 44. The output cam follower 46 is then retracted permitting the output valve 63 to open. The pump plunger 64 is activated by the pump cam follower 48 to push fluid out through the conduit and into the output tube. Then the output valve 63 is again closed by the output cam follower 46.
  • the pump cam follower 48 and the input cam follower 50 are retracted to permit the pump plunger 64 and the input valve 66 to open, thereby permitting the pump tube to refill with fluid.
  • fluid is pumped out of the fluid source pouch 44.
  • the rate of pumping is controlled by the speed of the motor 54 which is monitored by the timing printed circuit board 60.
  • a programmable microprocessor is provided on a control circuit board 76.
  • Each of the four pump motors is controlled by the controller board 76. Since each fluid source has its own pump and pump motor, the rate and sequence of fluid infusion is entirely flexible. Infusions may take place concurrently or sequentially and at any rate. The desired sequence and rates of infusion are programmed into the controller board 76 through the programming jacks 16.
  • the pump of the present invention provides physicians with the great latitude for selecting multiple-fluid drug regimens for treating patient illnesses.
  • the present invention allows for a cam follower to be in the lowered position. In such a position, the cam follower would block a cartridge from being slid into its space. However, when the cartridge is swung into position, the extended cam follower merely pushes up against its corresponding plunger member.

Abstract

A pump housing which contains a plurality of linear peristaltic pumps and receives a fluid source cartridge. The cartridge is provided with retaining knobs for engaging retaining holes in the front end of the pump housing. A cartridge further contains a tab at its rear end for engaging a locking mechanism in the pump housing. The cartridge contains linear fluid conduits which align with the linear peristaltic pumps for pumping fluid from the fluid source pouches within the cartridge. Each pump is individually controlled by a programmable controller within the pump.

Description

BACKGROUND OF THE INVENTION
This invention relates to a multiple fluid cartridge which is insertable into a programmable infusion pump.
It is an object of this invention to provide a compact, lightweight infusion pump which may be used for ambulatory patients. It is a further object of this invention to provide a pump which can be conveniently used with fluid source cartridges.
There has been a demonstrated need for pumps which can intravenously administer a plurality of drug solutions. For example, multiple drug chemotherapy treatments have been used to treat diseases such as cancer. Many of the drugs used in chemotherapy and other therapies cannot be mixed together prior to an infusion. Some of these drugs react to neutralize one another. Other drugs react to form precipitates which may block the catheter tube, or possibly cause an embolism in the patient.
Pumps have been developed which can concurrently pump a plurality of fluids through a multilumen catheter into a patient. The multilumen catheter keeps the drugs separate until they reach the bloodstream. For example, in U.S. Pat. No. 4,741,736 (Brown), a pump is disclosed which uses a roller to push fluid out of a plurality of compartments in an infusion pump. The different fluids in each of the compartment is pumped out at the same time by the action of the single roller
In infusion pump patent, U.S. Pat. No. 4,666,430 (Brown and Tai), a multiple syringe pump is disclosed in which a canister of compressed gas serves as the power source for pumping fluid out of a syringe. All of the syringes are controlled by the same canister of gas, and variation in the pumping rate of a syringe is controlled by valves on the outlets of the syringes.
An object of the present invention is to provide in a single ambulatory housing, separately controlled pumping mechanisms for each of a plurality of fluid sources. It is a still further object of the present invention to provide multiple fluid source cartridges which are attachable to a pump of the present invention.
SUMMARY OF THE INVENTION
The present invention is directed to an infusion pump system including a fluid source cartridge which is attachable to a pump housing. The pump housing has a plurality of linear peristaltic pumps. Each fluid source in the cartridge has a linear fluid conduit which aligns with a peristaltic pump when the cartridge is inserted into the housing. The pumping of fluid from any of the fluid sources in the cartridge is controlled by the source's respective peristaltic pump.
The infusion pump housing may be advantageously provided with a programmable controller to permit individual control over each of the peristaltic pumps. This permits operating the pumps sequentially or concurrently and at any selected pumping rate.
The multiple fluid source cartridge may be further provided with a module containing a plurality of plunger members. Each module overlies a linear conduit and the plunger members are alternately moved by the fingers of the peristaltic pump in the pump housing to cause fluid to be pumped from its respective fluid source. The same cartridge may be used for any number from one to four fluid sources, it being only necessary to provide the appropriate number of plunger modules in the cartridge.
Other objects and advantages of the present invention will become apparent during the following description of the presently preferred embodiment of the invention taken in conjunction with the drawings.
DETAILED DESCRIPTION OF THE DRAWINGS
FIG. 1 is a perspective view of the pump and cartridge of the present invention.
FIG. 2 is a side view illustrating how a cartridge attaches to a pump according to the present invention.
FIG. 3 is a plan view of a cartridge of the present invention with the top wall of the cartridge housing removed.
FIG. 4 is a bottom plan view of the pump of the present invention without a cartridge in place.
FIG. 5 is an end view of the pump of FIG. 4.
FIG. 6 is a side cross-sectional view of the pump and cartridge of the present invention.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
Referring now to FIG. 1, a pump housing 10 is provided for pumping fluid from a multiple fluid cartridge 20. The pump housing 10 is provided with a liquid crystal display 12, a keyboard 14 and as shown in FIG. 5, programming jacks 16. The underside of the pump housing 10 forms a cavity for receiving the cartridge 20. The cavity extends through one end of the pump housing 10. Just inside the open end of the housing, there are two cartridge retaining holes 18 for engaging retaining knobs 34 on the cartridge.
The cartridge 20 houses one or more fluid sources 44. The cartridge 20 further has space for four plunger modules 24. Each plunger module 24 has three plunger members which are used for pumping fluid through a linear fluid conduit positioned directly beneath the module 24. The inside end of the fluid conduit connects to one of the fluid sources in the body of the cartridge 20. At the outer end of the linear fluid conduit a connector 26 serves as the output port for delivering fluid into an output lumen.
In FIG. 1, all four lumens are being used by the cartridge 20. The lumens are fused together to form a multi-lumen tube for outputting the fluid to a connector for making connection with an implanted catheter, for example. The multi-lumen output tube may be connected to any of a variety of a multi-lumen connectors. Three possibilities are shown in FIG. 1. A needle connector 28 may be used in which each lumen is connected to a hollow injection needle. The needle connector may be inserted through a silicone block to make connection with a connector for a multi-lumen catheter. Another option is a multi-lumen connector such as that described in co-pending U.S. patent application Ser. No. 178,673 filed on Apr. 7, 1988, owned by the same assignee as the present invention. The disclosure of said application is hereby incorporated by reference herein. A third possibility for the output tube is to connect each lumen separately to a luer connector 32 so that individual connections can be made to four separate catheter lines.
The cartridge 20 is provided with a retaining knob 34 on two opposite sides near its front end. The retaining knob 34 is preferably a linear flange cocked at an angle with respect to the bottom of the cartridge. Preferably, the knob 34 is cocked at approximately a 45 degree angle with respect to the bottom of the cartridge, one end of the knob pointing towards the top of the cartridge and the other end of the knob pointing towards the front end of the cartridge. This permits the end of the knob 34 which points towards the top of the cartridge to be inserted into the retaining hole 18 in the pump housing 10 while the rear of the cartridge 20 hangs below the pump as shown in FIG. 2. The retaining hole 18 has an entrance opening 19 at the front of the housing. Once the entire knob 34 has been inserted through the opening 19 into the retaining hole 18, the cartridge 20 can be swung upwards to fully engage the pump housing 10.
At the rear of the pump housing 10, a lock 36 is provided for engaging a tab 22 on the rear end of the cartridge. The lock 36 according to the presently preferred embodiment is provided with a beveled edge 38 and a retaining edge 39. A spring 40 urges the lock 36 to hold the cartridge in place. As the cartridge 20 is pushed up into the housing, the cartridge tab 22 slides along the beveled edge 38 and pushes the lock back against the action of the spring 40. Once the tab 22 gets above the retaining edge 39, the spring forces the lock back beneath the cartridge tab 22 so that the tab 22 is held up on top of the retaining edge 39. Thus, the lock 36 prevents the cartridge 20 from falling out of the pump housing. At the front of the cartridge, the retaining knob 34 which entered the retaining holes 18 in a horizontal position are at an angle when the cartridge is fully inserted. Thus, the retaining knobs 34 cannot slide out of the retaining holes 18.
The cartridge lock 36 of the pump housing is further shown in FIG. 4, where it can be seen that the lock 36 swivels about an axis 41. The spring 40 urges the engaging end of the lock 36 against the cartridge 20. A cartridge can be released from the pump housing 10 by pushing against the other end of the lock 36 which forms a button 42 through an opening in the pump housing. When button 42 is pressed, the lock 36 swings away from the cartridge 20, permitting the tab 22 to disengage from the retaining edge 39 of the lock. Thus, the back end of the cartridge can fall out of the pump housing and when the retaining knobs 34 are in horizontal position with respect to the pump housing, they may be slid out through the openings 19.
FIG. 3 reveals the fluid sources stored within the cartridge 20. Each fluid source 44 is provided with a linear fluid conduit 45 beneath a plunger module 24. The fluid sources 44 are flexible pouches. The presently suggested procedure for using the cartridges 20 is to provide them with empty pouches. The desired fluid is injected into the connector port 26, using a syringe or other conventional means. After filling the pouch 44 with the desired amount of fluid, the connector port 26 is attached to the output tube. When all of the pouches are filled with their fluid, the cartridge may be inserted into the pump housing 10 and a purge cycle may be run on each of the fluid sources to pump out all of the air which may have gotten into the pouch or conduit line. After purging the air, the cartridge 20 is ready for use in an infusion.
Referring now to FIGS. 4 and 6, the pump of the present invention is provided with a plurality, four in this case, of linear peristaltic pumps. Linear peristaltic pumps are well known and any conventional design may be used to accomplish the objectives of the present invention. The pump of the preferred embodiment is a three finger pump, called such because of the three cams which are repeatedly lowered and raised to provide the desired pumping action. Each pump thus activates three cam followers, including an output cam follower 46 and a pump cam follower 48 and an input cam follower 50. Power for the pumps is provided by a battery which may be loaded into a cavity behind a battery cover 52 alongside the peristaltic pumps within the housing 10. Each pump is provided with its own motor 54 which turns a cam shaft 56. The cam shaft 56 is provided with a timing disk 58. The timing disk is read by a timing circuit on a printed circuit board 60. Signal feedback from the timing circuit on the printed circuit board 60 can be provided to control the speed of the motor 54 and thus control the rate of fluid infusion from any of the fluid sources. A spring 62 is located about each of the cam followers to urge the cam follower into a retracted position.
The cam followers interact with the plungers of the plunger module 24. Each plunger module 24 includes an output valve 63, a pump 64 and an input valve 66. The linear fluid conduit 45 beneath each plunger assembly 24 is provided through a silicone block 68. A silicone block 68 is provided in each of the plunger modules. A connector 70 at the end of the fluid conduit within the cartridge 20 is used for attaching the conduit to its respective fluid source 44. Each linear conduit 45 has an enlarged portion beneath the pump plunger 64. This enlarged portion of the conduit is called a pump tube 74.
Pumping is performed as follows. With the pump plunger 64 and the input valve 66 retracted, the output cam follower 46 is lowered against the output valve 63 to close off the fluid conduits. This permits the pump tube 74 to fill with fluid. Next, the input valve 66 is lowered by the input cam follower 50 to close off the pump tube 74 and prevent fluid from flowing back into the fluid source 44. The output cam follower 46 is then retracted permitting the output valve 63 to open. The pump plunger 64 is activated by the pump cam follower 48 to push fluid out through the conduit and into the output tube. Then the output valve 63 is again closed by the output cam follower 46. The pump cam follower 48 and the input cam follower 50 are retracted to permit the pump plunger 64 and the input valve 66 to open, thereby permitting the pump tube to refill with fluid. Thus, fluid is pumped out of the fluid source pouch 44. The rate of pumping is controlled by the speed of the motor 54 which is monitored by the timing printed circuit board 60.
A programmable microprocessor is provided on a control circuit board 76. Each of the four pump motors is controlled by the controller board 76. Since each fluid source has its own pump and pump motor, the rate and sequence of fluid infusion is entirely flexible. Infusions may take place concurrently or sequentially and at any rate. The desired sequence and rates of infusion are programmed into the controller board 76 through the programming jacks 16. Thus, in accordance with the present invention, multiple fluid infusion treatments may be delivered to a patient in any number of sequences and rates with an ambulatory pump. Thus, the pump of the present invention provides physicians with the great latitude for selecting multiple-fluid drug regimens for treating patient illnesses.
It is further noted that by swinging the cartridges into the cartridge receiving space of the pump housing, rather than sliding the cartridge into that space, the present invention allows for a cam follower to be in the lowered position. In such a position, the cam follower would block a cartridge from being slid into its space. However, when the cartridge is swung into position, the extended cam follower merely pushes up against its corresponding plunger member.
Of course, it should be understood that various changes and modifications to the prefered embodiment described above will be apparent to those skilled in the art. For example, any number of fluid sources may be provided in a cartridge. Also, if a pump ensured that all the cam followers were retracted, the cartridge could be inserted by sliding it into place. These and other changes can be made without departing from the spirit and scope of the invention and without diminishing its attendant advantages. It is therefore intended that such changes and modifications be covered by the following claims.

Claims (4)

I claim:
1. A multiple fluid source cartridge comprising;
a rigid housing;
a plurality of fluid containing compartments located within said housing;
a linear conduit connected to each one of said fluid containing compartments;
a plurality of plunger members superposed on each of said linear conduits; and
an output port accessible from outside said housing for each of said linear fluid conduits.
2. The cartride of claim 1 further comprising a detachable module for housing each plurality of plunger members.
3. The cartridge of claim 1 wherein said output port for each of said linear fluid conduits connects to a multilumen catheter.
4. The cartridge of claim 1 wherein said fluid containing compartments comprise flexible pouches.
US07/216,512 1988-07-08 1988-07-08 Multiple fluid cartridge and pump Expired - Lifetime US4950245A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US07/216,512 US4950245A (en) 1988-07-08 1988-07-08 Multiple fluid cartridge and pump
US07/301,628 US5011378A (en) 1988-07-08 1989-01-24 Pump tube mount and cartridge for infusion pump
US07/351,981 US5131816A (en) 1988-07-08 1989-05-15 Cartridge fed programmable ambulatory infusion pumps powered by DC electric motors
EP19890111139 EP0354324A3 (en) 1988-07-08 1989-06-19 Cartridge-type programmable ambulatory infusion pump
JP1174111A JPH0482564A (en) 1988-07-08 1989-07-07 Injection pump device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/216,512 US4950245A (en) 1988-07-08 1988-07-08 Multiple fluid cartridge and pump

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US07/301,628 Continuation-In-Part US5011378A (en) 1988-07-08 1989-01-24 Pump tube mount and cartridge for infusion pump
US07/351,981 Continuation-In-Part US5131816A (en) 1988-07-08 1989-05-15 Cartridge fed programmable ambulatory infusion pumps powered by DC electric motors

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US4950245A true US4950245A (en) 1990-08-21

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Cited By (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057081A (en) * 1990-06-15 1991-10-15 Sherwood Medical Company Peristaltic infusion device
US5131816A (en) * 1988-07-08 1992-07-21 I-Flow Corporation Cartridge fed programmable ambulatory infusion pumps powered by DC electric motors
US5171301A (en) * 1991-10-15 1992-12-15 Imed Corporation Multiple mini-pump infusion system
US5207645A (en) * 1991-06-25 1993-05-04 Medication Delivery Devices Infusion pump, treatment fluid bag therefor, and method for the use thereof
US5256157A (en) * 1991-01-31 1993-10-26 Baxter International Inc. Automated infusion pump with replaceable memory cartridges
US5277175A (en) * 1991-07-12 1994-01-11 Riggs John H Continuous flow nebulizer apparatus and method, having means maintaining a constant-level reservoir
US5355872A (en) * 1992-03-04 1994-10-18 Riggs John H Low flow rate nebulizer apparatus and method of nebulization
US5454792A (en) * 1993-04-19 1995-10-03 Hyproteck, Inc. Linear slide valve for CVC access
US5564915A (en) * 1993-10-28 1996-10-15 Sims Deltec, Inc. Pressure plate for pump and reservoir enclosure
US5567136A (en) * 1993-10-28 1996-10-22 Sims Deltec, Inc. Pressure plate for pump and reservoir enclosure
US5569181A (en) * 1993-10-28 1996-10-29 Medrad, Inc. Sterility assurance for contrast delivery system
US5588816A (en) * 1993-05-26 1996-12-31 Quest Medical, Inc. Disposable cassette for cardioplegia delivery system
USRE35501E (en) * 1991-06-25 1997-05-06 Medication Delivery Devices Infusion pump, treatment fluid bag therefor, and method for the use thereof
US5634896A (en) * 1993-03-03 1997-06-03 Deka Products Limited Partnership Liquid pumping mechanisms for peritoneal dialysis systems employing fluid pressure
US5739508A (en) * 1994-07-12 1998-04-14 Medrad, Inc. Closed loop information path for medical fluid delivery systems
US5806519A (en) * 1993-10-28 1998-09-15 Medrad, Inc. Total system for contrast delivery
US5840026A (en) * 1994-09-21 1998-11-24 Medrad, Inc. Patient specific dosing contrast delivery systems and methods
US5843037A (en) * 1993-10-28 1998-12-01 Medrad Inc. Multipatient fluid dispensing
US5879143A (en) * 1996-04-26 1999-03-09 Sims Deltec, Inc. Reservoir enclosure adaptors and methods
US5911716A (en) * 1992-01-24 1999-06-15 I-Flow Corporation Platen pump
US5941696A (en) * 1996-09-10 1999-08-24 Embrex, Inc. Peristaltic pump
USD418219S (en) * 1995-02-09 1999-12-28 Zambon Group S.P.A. Programmable pump for infusion
US6063052A (en) * 1993-10-28 2000-05-16 Medrad, Inc. Injection system and pumping system for use therein
US6251098B1 (en) 1992-01-24 2001-06-26 I-Flow, Corp. Fluid container for use with platen pump
US6345962B1 (en) 2000-05-22 2002-02-12 Douglas E. Sutter Fluid operated pump
US6358239B1 (en) 1992-01-24 2002-03-19 I-Flow Corporation Platen pump
US20020045856A1 (en) * 2000-05-10 2002-04-18 Ali Jaafar Apparatus and method for out-of-hospital thrombolytic therapy
US6482171B1 (en) * 1991-07-16 2002-11-19 Heartport, Inc. Multi-lumen catheter
US20030169234A1 (en) * 2002-03-05 2003-09-11 Kempisty Mark S. Remote control system including an on-screen display (OSD)
US20030181866A1 (en) * 2002-03-21 2003-09-25 Kent Abrahamson Pump and tube set thereof
US6668753B2 (en) 2002-02-13 2003-12-30 Embrex, Inc. Methods and apparatus for delivering fluid to egg injection devices
US20040127816A1 (en) * 2002-12-30 2004-07-01 Adriano Braun Galvao Handheld blood collection device
US20040158189A1 (en) * 2003-02-07 2004-08-12 Claudio Tonelli Integrated blood treatment module and extracorporeal blood treatment apparatus
US20040158190A1 (en) * 2003-02-07 2004-08-12 Jacques Duchamp Support element for an integrated module for blood treatment, an integrated module for blood treatment, and a manufacturing process for an integrated module for blood treatment
US20040162513A1 (en) * 2003-02-07 2004-08-19 Roberto Neri Support element, an integrated module for extracorporeal blood treatment comprising the support element, an apparatus for extracorporeal blood treatment equipped with the integrated module, and an assembly process for an integrated module for extracorporeal blood treatment
US20040167457A1 (en) * 2003-02-07 2004-08-26 Claudio Tonelli Support element for an integrated blood treatment module, integrated blood treatment module and extracorporeal blood treatment apparatus equipped with said integrated module
US6783514B2 (en) * 1997-01-31 2004-08-31 United States Surgical Corporation Fibrin sealant applicator
US20050011823A1 (en) * 2003-02-07 2005-01-20 Annalisa Delnevo Extracorporeal blood treatment machine
US20050033245A1 (en) * 2002-03-21 2005-02-10 Kent Abrahamson Pump and tube set thereof
US20050247203A1 (en) * 2002-06-24 2005-11-10 Jacques Chevallet Gas separation devices
US20080215029A1 (en) * 1993-01-22 2008-09-04 I-Flow Corporation Platen pump
US20080275422A1 (en) * 2007-05-02 2008-11-06 Cardinal Health 303, Inc. Intravenous Fluid Container
US20090149743A1 (en) * 2005-11-21 2009-06-11 Acist Medical Systems, Inc. Medical Fluid Injection System
WO2009086182A1 (en) * 2007-12-21 2009-07-09 Carticept Medical, Inc. Articular injection system
US20110021905A1 (en) * 2007-12-21 2011-01-27 Carticept Medical, Inc. Injection system for delivering multiple fluids within the anatomy
US7925330B2 (en) 2004-11-24 2011-04-12 Medrad, Inc. Devices, systems and methods for determining parameters of one or more phases of an injection procedure
US7934912B2 (en) 2007-09-27 2011-05-03 Curlin Medical Inc Peristaltic pump assembly with cassette and mounting pin arrangement
US8062008B2 (en) 2007-09-27 2011-11-22 Curlin Medical Inc. Peristaltic pump and removable cassette therefor
EP2390506A1 (en) * 2010-03-23 2011-11-30 Andreas Hettich GmbH&Co. KG Device for supplying fluid and controlling a fluid system
US8083503B2 (en) 2007-09-27 2011-12-27 Curlin Medical Inc. Peristaltic pump assembly and regulator therefor
US8197235B2 (en) 2009-02-18 2012-06-12 Davis David L Infusion pump with integrated permanent magnet
US8353864B2 (en) 2009-02-18 2013-01-15 Davis David L Low cost disposable infusion pump
US20140356193A1 (en) * 2011-09-21 2014-12-04 Sanofi-Aventis Deutschland Gmbh Peristaltic Pump and Method of Transporting Material with a Peristaltic Pump
US9008759B2 (en) 2007-07-17 2015-04-14 Bayer Medical Care Inc. Devices and systems for determination of parameters for a procedure, for estimation of cardiopulmonary function and for fluid delivery
US9044542B2 (en) 2007-12-21 2015-06-02 Carticept Medical, Inc. Imaging-guided anesthesia injection systems and methods
US9302044B2 (en) 2006-12-29 2016-04-05 Bayer Healthcare Llc Patient-based parameter generation systems for medical injection procedures
US9421330B2 (en) 2008-11-03 2016-08-23 Bayer Healthcare Llc Mitigation of contrast-induced nephropathy
US9616166B2 (en) 2004-11-16 2017-04-11 Bayer Healthcare Llc Systems and methods of determining injection protocols for diagnostic imaging procedures
US9700672B2 (en) 2011-09-21 2017-07-11 Bayer Healthcare Llc Continuous multi-fluid pump device, drive and actuating system and method
US9949704B2 (en) 2012-05-14 2018-04-24 Bayer Healthcare Llc Systems and methods for determination of pharmaceutical fluid injection protocols based on x-ray tube voltage
US9959389B2 (en) 2010-06-24 2018-05-01 Bayer Healthcare Llc Modeling of pharmaceutical propagation and parameter generation for injection protocols
US10006454B2 (en) 2011-08-02 2018-06-26 Baxter International Inc. Infusion pump with independently controllable valves and low power operation and methods thereof
US10357602B2 (en) * 2007-05-02 2019-07-23 Carefusion 303, Inc. Automated intravenous fluid container delivery device and system
US10507319B2 (en) 2015-01-09 2019-12-17 Bayer Healthcare Llc Multiple fluid delivery system with multi-use disposable set and features thereof
WO2020076917A1 (en) * 2018-10-09 2020-04-16 University Of Washington Integrated multi-medication treatment delivery system
US10898638B2 (en) 2016-03-03 2021-01-26 Bayer Healthcare Llc System and method for improved fluid delivery in multi-fluid injector systems
WO2021041313A1 (en) * 2019-08-30 2021-03-04 Fresenius Medical Care Holdings, Inc. Multi-lumen tube assemblies for medical fluid pumping systems
USD914197S1 (en) 2018-08-16 2021-03-23 Deka Products Limited Partnership Syringe pump
USD914196S1 (en) * 2018-08-16 2021-03-23 Deka Products Limited Partnership Peristaltic pump
USD914195S1 (en) 2018-08-16 2021-03-23 Deka Products Limited Partnership Syringe pump
WO2021072263A1 (en) * 2019-10-11 2021-04-15 Merit Medical Systems, Inc. Keyed fluid line connectors and methods
USD918396S1 (en) 2018-08-16 2021-05-04 Deka Products Limited Partnership Central controller
US11141535B2 (en) 2017-08-31 2021-10-12 Bayer Healthcare Llc Fluid path impedance assessment for improving fluid delivery performance
US11224551B2 (en) 2007-05-02 2022-01-18 Carefusion 303, Inc. Automated intravenous fluid container delivery device and system
US11278853B2 (en) 2013-03-13 2022-03-22 Bayer Healthcare Llc Method for controlling fluid accuracy and backflow compensation
US11478581B2 (en) 2017-08-31 2022-10-25 Bayer Healthcare Llc Fluid injector system volume compensation system and method
USD978352S1 (en) 2020-10-28 2023-02-14 Smiths Medical Asd, Inc. Cartridge cap
US11598664B2 (en) 2017-08-31 2023-03-07 Bayer Healthcare Llc Injector pressure calibration system and method
US11779702B2 (en) 2017-08-31 2023-10-10 Bayer Healthcare Llc Method for dynamic pressure control in a fluid injector system
US11786652B2 (en) 2017-08-31 2023-10-17 Bayer Healthcare Llc System and method for drive member position and fluid injector system mechanical calibration
US11806506B2 (en) * 2020-06-01 2023-11-07 DASH Anesthesia Intravenous fluid delivery system and apparatus

Citations (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2351828A (en) * 1942-01-08 1944-06-20 G L Meyers Surgical pump
US4094318A (en) * 1976-07-09 1978-06-13 Burron Medical Products, Inc. Electronic control means for a plurality of intravenous infusion sets
US4142524A (en) * 1977-06-02 1979-03-06 Andros Incorporated Cassette for intravenous delivery system
US4199307A (en) * 1977-07-05 1980-04-22 Andros Incorporated Medical infusion system
US4273121A (en) * 1978-02-17 1981-06-16 Andros Incorporated Medical infusion system
US4340153A (en) * 1980-11-28 1982-07-20 Spivey David L Method and apparatus for medication dispensing
US4397639A (en) * 1980-04-24 1983-08-09 Ferring Arzneimittel Gmbh Device for the intermittent pulsatory application of fluid medicaments
US4479797A (en) * 1981-07-04 1984-10-30 Terumo Corporation Medication infusion device
US4497370A (en) * 1982-08-12 1985-02-05 Breslin Michael K Apparatus and method for recovery of liquid hydrocarbons from ground water
US4498843A (en) * 1982-08-02 1985-02-12 Schneider Philip H Insulin infusion pump
US4563175A (en) * 1983-12-19 1986-01-07 Lafond Margaret Multiple syringe pump
DE3500467A1 (en) * 1985-01-09 1986-07-10 Bernard, geb.Kaemmerer, Ingrid, 4803 Steinhagen Variable infusion device for medical purposes
US4601700A (en) * 1984-05-21 1986-07-22 Quest Medical, Inc. Method for flow control monitoring
US4650469A (en) * 1984-10-19 1987-03-17 Deltec Systems, Inc. Drug delivery system
US4653987A (en) * 1984-07-06 1987-03-31 Tsuyoshi Tsuji Finger peristaltic infusion pump
US4657490A (en) * 1985-03-27 1987-04-14 Quest Medical, Inc. Infusion pump with disposable cassette
US4666430A (en) * 1984-12-05 1987-05-19 I-Flow Corporation Infusion pump
US4673390A (en) * 1984-11-29 1987-06-16 Minnesota Mining & Manufacturing Company Multiple solution IV system
US4696671A (en) * 1984-02-08 1987-09-29 Omni-Flow, Inc. Infusion system having plural fluid input ports and at least one patient output port
US4705506A (en) * 1984-11-29 1987-11-10 Minnesota Mining And Manufacturing Company Multiple solution IV system with setup error protection
US4718467A (en) * 1986-05-30 1988-01-12 Baxter Travenol Laboratories, Inc. Pumping module arrangement and manifold
US4725205A (en) * 1987-01-30 1988-02-16 Fisher Scientific Group Inc. Peristaltic pump with cam action compensator
US4728265A (en) * 1987-01-30 1988-03-01 Fisher Scientific Group Inc. Peristaltic pump with cam action compensator
US4731057A (en) * 1985-08-05 1988-03-15 Nikkiso Co., Ltd. Transfusion apparatus
US4734092A (en) * 1987-02-18 1988-03-29 Ivac Corporation Ambulatory drug delivery device
US4741736A (en) * 1986-12-10 1988-05-03 I-Flow Corporation Programmable infusion pump
US4756706A (en) * 1985-01-23 1988-07-12 American Hospital Supply Corporation Centrally managed modular infusion pump system
US4850972A (en) * 1987-01-16 1989-07-25 Pacesetter Infusion, Ltd. Progammable multiple pump medication infusion system with printer
US4865584A (en) * 1984-02-08 1989-09-12 Omni-Flow, Inc. Cassette for programable multiple input infusion system

Patent Citations (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2351828A (en) * 1942-01-08 1944-06-20 G L Meyers Surgical pump
US4094318A (en) * 1976-07-09 1978-06-13 Burron Medical Products, Inc. Electronic control means for a plurality of intravenous infusion sets
US4142524A (en) * 1977-06-02 1979-03-06 Andros Incorporated Cassette for intravenous delivery system
US4199307A (en) * 1977-07-05 1980-04-22 Andros Incorporated Medical infusion system
US4273121A (en) * 1978-02-17 1981-06-16 Andros Incorporated Medical infusion system
US4397639A (en) * 1980-04-24 1983-08-09 Ferring Arzneimittel Gmbh Device for the intermittent pulsatory application of fluid medicaments
US4340153A (en) * 1980-11-28 1982-07-20 Spivey David L Method and apparatus for medication dispensing
US4479797A (en) * 1981-07-04 1984-10-30 Terumo Corporation Medication infusion device
US4498843A (en) * 1982-08-02 1985-02-12 Schneider Philip H Insulin infusion pump
US4497370A (en) * 1982-08-12 1985-02-05 Breslin Michael K Apparatus and method for recovery of liquid hydrocarbons from ground water
US4563175A (en) * 1983-12-19 1986-01-07 Lafond Margaret Multiple syringe pump
US4865584A (en) * 1984-02-08 1989-09-12 Omni-Flow, Inc. Cassette for programable multiple input infusion system
US4696671A (en) * 1984-02-08 1987-09-29 Omni-Flow, Inc. Infusion system having plural fluid input ports and at least one patient output port
US4601700A (en) * 1984-05-21 1986-07-22 Quest Medical, Inc. Method for flow control monitoring
US4653987A (en) * 1984-07-06 1987-03-31 Tsuyoshi Tsuji Finger peristaltic infusion pump
US4650469A (en) * 1984-10-19 1987-03-17 Deltec Systems, Inc. Drug delivery system
US4673390A (en) * 1984-11-29 1987-06-16 Minnesota Mining & Manufacturing Company Multiple solution IV system
US4705506A (en) * 1984-11-29 1987-11-10 Minnesota Mining And Manufacturing Company Multiple solution IV system with setup error protection
US4666430A (en) * 1984-12-05 1987-05-19 I-Flow Corporation Infusion pump
DE3500467A1 (en) * 1985-01-09 1986-07-10 Bernard, geb.Kaemmerer, Ingrid, 4803 Steinhagen Variable infusion device for medical purposes
US4756706A (en) * 1985-01-23 1988-07-12 American Hospital Supply Corporation Centrally managed modular infusion pump system
US4657490A (en) * 1985-03-27 1987-04-14 Quest Medical, Inc. Infusion pump with disposable cassette
US4731057A (en) * 1985-08-05 1988-03-15 Nikkiso Co., Ltd. Transfusion apparatus
US4718467A (en) * 1986-05-30 1988-01-12 Baxter Travenol Laboratories, Inc. Pumping module arrangement and manifold
US4741736A (en) * 1986-12-10 1988-05-03 I-Flow Corporation Programmable infusion pump
US4850972A (en) * 1987-01-16 1989-07-25 Pacesetter Infusion, Ltd. Progammable multiple pump medication infusion system with printer
US4725205A (en) * 1987-01-30 1988-02-16 Fisher Scientific Group Inc. Peristaltic pump with cam action compensator
US4728265A (en) * 1987-01-30 1988-03-01 Fisher Scientific Group Inc. Peristaltic pump with cam action compensator
US4734092A (en) * 1987-02-18 1988-03-29 Ivac Corporation Ambulatory drug delivery device

Cited By (149)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5131816A (en) * 1988-07-08 1992-07-21 I-Flow Corporation Cartridge fed programmable ambulatory infusion pumps powered by DC electric motors
US5057081A (en) * 1990-06-15 1991-10-15 Sherwood Medical Company Peristaltic infusion device
US5256157A (en) * 1991-01-31 1993-10-26 Baxter International Inc. Automated infusion pump with replaceable memory cartridges
US5207645A (en) * 1991-06-25 1993-05-04 Medication Delivery Devices Infusion pump, treatment fluid bag therefor, and method for the use thereof
US5433704A (en) * 1991-06-25 1995-07-18 Medication Delivery Devices Infusion pump, treatment fluid bag therefor, and method for the use thereof
US5743878A (en) * 1991-06-25 1998-04-28 Medication Delivery Devices, Inc. Infusion pump, treatment fluid bag therefor, and method for the use thereof
USRE35501E (en) * 1991-06-25 1997-05-06 Medication Delivery Devices Infusion pump, treatment fluid bag therefor, and method for the use thereof
US5584811A (en) * 1991-06-25 1996-12-17 Medication Delivery Devices, Inc. Infusion pump, treatment fluid bag therefor, and method for the use thereof
US5277175A (en) * 1991-07-12 1994-01-11 Riggs John H Continuous flow nebulizer apparatus and method, having means maintaining a constant-level reservoir
US6482171B1 (en) * 1991-07-16 2002-11-19 Heartport, Inc. Multi-lumen catheter
US5171301A (en) * 1991-10-15 1992-12-15 Imed Corporation Multiple mini-pump infusion system
US6358239B1 (en) 1992-01-24 2002-03-19 I-Flow Corporation Platen pump
US6871759B2 (en) 1992-01-24 2005-03-29 I-Flow Corporation Platen pump
US20040108333A1 (en) * 1992-01-24 2004-06-10 Rake Kenneth W. Platen pump
US20050211725A1 (en) * 1992-01-24 2005-09-29 Rake Kenneth W Platen pump
US7083068B2 (en) 1992-01-24 2006-08-01 I-Flow Corporation Platen pump
US6251098B1 (en) 1992-01-24 2001-06-26 I-Flow, Corp. Fluid container for use with platen pump
US5911716A (en) * 1992-01-24 1999-06-15 I-Flow Corporation Platen pump
US7337922B2 (en) 1992-01-24 2008-03-04 I-Flow Corporation Platen pump
US5355872A (en) * 1992-03-04 1994-10-18 Riggs John H Low flow rate nebulizer apparatus and method of nebulization
US20080215029A1 (en) * 1993-01-22 2008-09-04 I-Flow Corporation Platen pump
US5634896A (en) * 1993-03-03 1997-06-03 Deka Products Limited Partnership Liquid pumping mechanisms for peritoneal dialysis systems employing fluid pressure
US5454792A (en) * 1993-04-19 1995-10-03 Hyproteck, Inc. Linear slide valve for CVC access
US5588816A (en) * 1993-05-26 1996-12-31 Quest Medical, Inc. Disposable cassette for cardioplegia delivery system
US5806519A (en) * 1993-10-28 1998-09-15 Medrad, Inc. Total system for contrast delivery
US6731971B2 (en) 1993-10-28 2004-05-04 Medrad, Inc. Fluid delivery system including a reusable flow path and a per-patient disposable fluid path
US6063052A (en) * 1993-10-28 2000-05-16 Medrad, Inc. Injection system and pumping system for use therein
US6149627A (en) * 1993-10-28 2000-11-21 Medrad, Inc. Multi-patient fluid dispensing
US7427281B2 (en) 1993-10-28 2008-09-23 Medrad, Inc. Method of delivering fluid mixtures to multiple patients
US6306117B1 (en) 1993-10-28 2001-10-23 Medrad, Inc. Multi-patient fluid dispensing
US5843037A (en) * 1993-10-28 1998-12-01 Medrad Inc. Multipatient fluid dispensing
US5564915A (en) * 1993-10-28 1996-10-15 Sims Deltec, Inc. Pressure plate for pump and reservoir enclosure
US5567136A (en) * 1993-10-28 1996-10-22 Sims Deltec, Inc. Pressure plate for pump and reservoir enclosure
US6901283B2 (en) 1993-10-28 2005-05-31 Medrad, Inc. Adjusting a condition of a fluid medium to produce an image of a patient
US6442418B1 (en) 1993-10-28 2002-08-27 Medrad, Inc. Total system for contrast delivery
US5569181A (en) * 1993-10-28 1996-10-29 Medrad, Inc. Sterility assurance for contrast delivery system
US5739508A (en) * 1994-07-12 1998-04-14 Medrad, Inc. Closed loop information path for medical fluid delivery systems
US5920054A (en) * 1994-07-12 1999-07-06 Medrad, Inc. Closed loop information path for medical fluid delivery systems
US5840026A (en) * 1994-09-21 1998-11-24 Medrad, Inc. Patient specific dosing contrast delivery systems and methods
US6889074B2 (en) 1994-09-21 2005-05-03 Medrad, Inc. Patient specific dosing contrast delivery systems and methods
US7313431B2 (en) 1994-09-21 2007-12-25 Medrad, Inc. System and method for inflating a balloon catheter and delivering fluid media to a patient
US6385483B1 (en) 1994-09-21 2002-05-07 Medrad, Inc. Patient specific dosing contrast delivery systems and methods
USD418219S (en) * 1995-02-09 1999-12-28 Zambon Group S.P.A. Programmable pump for infusion
US5879143A (en) * 1996-04-26 1999-03-09 Sims Deltec, Inc. Reservoir enclosure adaptors and methods
US5941696A (en) * 1996-09-10 1999-08-24 Embrex, Inc. Peristaltic pump
US6783514B2 (en) * 1997-01-31 2004-08-31 United States Surgical Corporation Fibrin sealant applicator
US20020045856A1 (en) * 2000-05-10 2002-04-18 Ali Jaafar Apparatus and method for out-of-hospital thrombolytic therapy
US6699230B2 (en) * 2000-05-10 2004-03-02 Minnesota Medical Physics, Llc Apparatus and method for out-of-hospital thrombolytic therapy
US6345962B1 (en) 2000-05-22 2002-02-12 Douglas E. Sutter Fluid operated pump
US6668753B2 (en) 2002-02-13 2003-12-30 Embrex, Inc. Methods and apparatus for delivering fluid to egg injection devices
US20030169234A1 (en) * 2002-03-05 2003-09-11 Kempisty Mark S. Remote control system including an on-screen display (OSD)
US20050033245A1 (en) * 2002-03-21 2005-02-10 Kent Abrahamson Pump and tube set thereof
US6942473B2 (en) 2002-03-21 2005-09-13 Hospira, Inc. Pump and tube set thereof
US20030181866A1 (en) * 2002-03-21 2003-09-25 Kent Abrahamson Pump and tube set thereof
US7517387B2 (en) 2002-06-24 2009-04-14 Gambro Lundia Ab Gas separation devices
US20050247203A1 (en) * 2002-06-24 2005-11-10 Jacques Chevallet Gas separation devices
US20040127816A1 (en) * 2002-12-30 2004-07-01 Adriano Braun Galvao Handheld blood collection device
US7314554B2 (en) 2003-02-07 2008-01-01 Gambro Lundia Ab Extracorporeal blood treatment machine
US20040162513A1 (en) * 2003-02-07 2004-08-19 Roberto Neri Support element, an integrated module for extracorporeal blood treatment comprising the support element, an apparatus for extracorporeal blood treatment equipped with the integrated module, and an assembly process for an integrated module for extracorporeal blood treatment
US7232418B2 (en) 2003-02-07 2007-06-19 Gambro Lundia Ab Support element, an integrated module for extracorporeal blood treatment comprising the support element, an apparatus for extracorporeal blood treatment equipped with the integrated module, and an assembly process for an integrated module for extracorporeal blood treatment
US7247146B2 (en) 2003-02-07 2007-07-24 Gambro Lundia Ab Support element for an integrated blood treatment module, integrated blood treatment module and extracorporeal blood treatment apparatus equipped with said integrated module
US20070181483A1 (en) * 2003-02-07 2007-08-09 Claudio Tonelli Integrated blood treatment module and extracorporeal blood treatment apparatus
US20070193940A1 (en) * 2003-02-07 2007-08-23 Gambro Lundia Ab Integrated module for blood treatment
US20070249983A1 (en) * 2003-02-07 2007-10-25 Gambro Lundia Ab Machine for extracorporeal blood treatment coupled to a support element
US20070293803A1 (en) * 2003-02-07 2007-12-20 Gambro Lundia Ab Integrated blood treatment module having a support element
US20040158190A1 (en) * 2003-02-07 2004-08-12 Jacques Duchamp Support element for an integrated module for blood treatment, an integrated module for blood treatment, and a manufacturing process for an integrated module for blood treatment
US20050011823A1 (en) * 2003-02-07 2005-01-20 Annalisa Delnevo Extracorporeal blood treatment machine
US20040158189A1 (en) * 2003-02-07 2004-08-12 Claudio Tonelli Integrated blood treatment module and extracorporeal blood treatment apparatus
US20080060988A1 (en) * 2003-02-07 2008-03-13 Annalisa Delnevo Extracorporeal blood treatment machine
US7223336B2 (en) 2003-02-07 2007-05-29 Gambro Lundia Ab Integrated blood treatment module and extracorporeal blood treatment apparatus
US7223338B2 (en) 2003-02-07 2007-05-29 Gambro Lundia Ab Support element for an integrated module for blood treatment, an integrated module for blood treatment, and a manufacturing process for an integrated module for blood treatment
US7867393B2 (en) 2003-02-07 2011-01-11 Gambro Lundia Ab Integrated module for blood treatment
US20040167457A1 (en) * 2003-02-07 2004-08-26 Claudio Tonelli Support element for an integrated blood treatment module, integrated blood treatment module and extracorporeal blood treatment apparatus equipped with said integrated module
US7993516B2 (en) 2003-02-07 2011-08-09 Gambro Lundia Ab Integrated blood treatment module and extracorporeal blood treatment apparatus
US7727391B2 (en) 2003-02-07 2010-06-01 Gambro Lundia Ab Extracorporeal blood treatment machine
US7641626B2 (en) 2003-02-07 2010-01-05 Gambro Lundia Ab Integrated blood treatment module having a support element
US7727176B2 (en) 2003-02-07 2010-06-01 Gambro Lundia Ab Machine for extracorporeal blood treatment coupled to a support element
US9616166B2 (en) 2004-11-16 2017-04-11 Bayer Healthcare Llc Systems and methods of determining injection protocols for diagnostic imaging procedures
US9950107B2 (en) 2004-11-24 2018-04-24 Bayer Healthcare Llc Systems and methods for managing workflow for injection procedures
US10166326B2 (en) 2004-11-24 2019-01-01 Bayer Healthcare Llc Devices, systems and methods for determining parameters of one or more phases of an injection procedure
US7925330B2 (en) 2004-11-24 2011-04-12 Medrad, Inc. Devices, systems and methods for determining parameters of one or more phases of an injection procedure
US9238099B2 (en) 2004-11-24 2016-01-19 Bayer Healthcare Llc System and apparatus for modeling pressures generated during an injection procedure
US20090149743A1 (en) * 2005-11-21 2009-06-11 Acist Medical Systems, Inc. Medical Fluid Injection System
US10226568B2 (en) 2005-11-21 2019-03-12 Acist Medical Systems, Inc. Customizable medical fluid injection system and method
US9259526B2 (en) 2005-11-21 2016-02-16 Acist Medical Systems, Inc. Medical fluid injection system and method for guided setup
US9457140B2 (en) 2005-11-21 2016-10-04 Acist Medical Systems, Inc. Medical fluid injection system
US9566381B2 (en) 2005-11-21 2017-02-14 Acist Medical Systems, Inc. Disposable fluid connector having multiple tubing components and an electrical connector
EP2468350A1 (en) * 2005-11-21 2012-06-27 ACIST Medical Systems, Inc. Medical fluid injection system
US10463782B2 (en) 2006-12-29 2019-11-05 Bayer Healthcare Llc Patient-based parameter generation systems for medical injection procedures
US9302044B2 (en) 2006-12-29 2016-04-05 Bayer Healthcare Llc Patient-based parameter generation systems for medical injection procedures
US20080275422A1 (en) * 2007-05-02 2008-11-06 Cardinal Health 303, Inc. Intravenous Fluid Container
US10357602B2 (en) * 2007-05-02 2019-07-23 Carefusion 303, Inc. Automated intravenous fluid container delivery device and system
US8257337B2 (en) * 2007-05-02 2012-09-04 Carefusion 303, Inc. Intravenous fluid container
US11224551B2 (en) 2007-05-02 2022-01-18 Carefusion 303, Inc. Automated intravenous fluid container delivery device and system
US9008759B2 (en) 2007-07-17 2015-04-14 Bayer Medical Care Inc. Devices and systems for determination of parameters for a procedure, for estimation of cardiopulmonary function and for fluid delivery
US8083503B2 (en) 2007-09-27 2011-12-27 Curlin Medical Inc. Peristaltic pump assembly and regulator therefor
US8062008B2 (en) 2007-09-27 2011-11-22 Curlin Medical Inc. Peristaltic pump and removable cassette therefor
US7934912B2 (en) 2007-09-27 2011-05-03 Curlin Medical Inc Peristaltic pump assembly with cassette and mounting pin arrangement
US9044542B2 (en) 2007-12-21 2015-06-02 Carticept Medical, Inc. Imaging-guided anesthesia injection systems and methods
US20110021905A1 (en) * 2007-12-21 2011-01-27 Carticept Medical, Inc. Injection system for delivering multiple fluids within the anatomy
US9067015B2 (en) 2007-12-21 2015-06-30 Carticept Medical, Inc. System for injecting fluids in a subject
US20150297831A1 (en) * 2007-12-21 2015-10-22 Carticept Medical, Inc. Systems and methods for injecting and aspirating fluids
US8007487B2 (en) 2007-12-21 2011-08-30 Carticept Medical, Inc. Method of treating a joint using an articular injection system
US8545440B2 (en) * 2007-12-21 2013-10-01 Carticept Medical, Inc. Injection system for delivering multiple fluids within the anatomy
US8425464B2 (en) 2007-12-21 2013-04-23 Carticept Medical, Inc. Imaging-guided anesthetic injection method
US9398894B2 (en) 2007-12-21 2016-07-26 Carticept Medical, Inc. Removable cassette for articular injection system
US8079976B2 (en) 2007-12-21 2011-12-20 Carticept Medical, Inc. Articular injection system
US8425463B2 (en) 2007-12-21 2013-04-23 Carticept Medical, Inc. Anesthetic injection system
US8142414B2 (en) 2007-12-21 2012-03-27 Carticept Medical, Inc. Methods of injecting fluids into joints using a handpiece assembly
WO2009086182A1 (en) * 2007-12-21 2009-07-09 Carticept Medical, Inc. Articular injection system
US8002736B2 (en) 2007-12-21 2011-08-23 Carticept Medical, Inc. Injection systems for delivery of fluids to joints
US9421330B2 (en) 2008-11-03 2016-08-23 Bayer Healthcare Llc Mitigation of contrast-induced nephropathy
US8197235B2 (en) 2009-02-18 2012-06-12 Davis David L Infusion pump with integrated permanent magnet
US8353864B2 (en) 2009-02-18 2013-01-15 Davis David L Low cost disposable infusion pump
EP2390506A1 (en) * 2010-03-23 2011-11-30 Andreas Hettich GmbH&Co. KG Device for supplying fluid and controlling a fluid system
US9959389B2 (en) 2010-06-24 2018-05-01 Bayer Healthcare Llc Modeling of pharmaceutical propagation and parameter generation for injection protocols
US10865786B2 (en) 2011-08-02 2020-12-15 Baxter International Inc. Infusion pump with independently controllable valves and low power operation and methods thereof
US10851773B2 (en) 2011-08-02 2020-12-01 Baxter International Inc. Infusion pump with independently controllable valves and low power operation and methods thereof
US10006454B2 (en) 2011-08-02 2018-06-26 Baxter International Inc. Infusion pump with independently controllable valves and low power operation and methods thereof
US9700672B2 (en) 2011-09-21 2017-07-11 Bayer Healthcare Llc Continuous multi-fluid pump device, drive and actuating system and method
US10519946B2 (en) * 2011-09-21 2019-12-31 Sanofi-Aventis Deutschland Gmbh Peristaltic pump and method of transporting material with a peristaltic pump
US20140356193A1 (en) * 2011-09-21 2014-12-04 Sanofi-Aventis Deutschland Gmbh Peristaltic Pump and Method of Transporting Material with a Peristaltic Pump
US11191501B2 (en) 2012-05-14 2021-12-07 Bayer Healthcare Llc Systems and methods for determination of pharmaceutical fluid injection protocols based on x-ray tube voltage
US9949704B2 (en) 2012-05-14 2018-04-24 Bayer Healthcare Llc Systems and methods for determination of pharmaceutical fluid injection protocols based on x-ray tube voltage
US11278853B2 (en) 2013-03-13 2022-03-22 Bayer Healthcare Llc Method for controlling fluid accuracy and backflow compensation
US10507319B2 (en) 2015-01-09 2019-12-17 Bayer Healthcare Llc Multiple fluid delivery system with multi-use disposable set and features thereof
US11491318B2 (en) 2015-01-09 2022-11-08 Bayer Healthcare Llc Multiple fluid delivery system with multi-use disposable set and features thereof
US11672902B2 (en) 2016-03-03 2023-06-13 Bayer Healthcare Llc System and method for improved fluid delivery in multi-fluid injector systems
US10898638B2 (en) 2016-03-03 2021-01-26 Bayer Healthcare Llc System and method for improved fluid delivery in multi-fluid injector systems
US11598664B2 (en) 2017-08-31 2023-03-07 Bayer Healthcare Llc Injector pressure calibration system and method
US11478581B2 (en) 2017-08-31 2022-10-25 Bayer Healthcare Llc Fluid injector system volume compensation system and method
US11141535B2 (en) 2017-08-31 2021-10-12 Bayer Healthcare Llc Fluid path impedance assessment for improving fluid delivery performance
US11826553B2 (en) 2017-08-31 2023-11-28 Bayer Healthcare Llc Fluid path impedance assessment for improving fluid delivery performance
US11786652B2 (en) 2017-08-31 2023-10-17 Bayer Healthcare Llc System and method for drive member position and fluid injector system mechanical calibration
US11779702B2 (en) 2017-08-31 2023-10-10 Bayer Healthcare Llc Method for dynamic pressure control in a fluid injector system
USD914195S1 (en) 2018-08-16 2021-03-23 Deka Products Limited Partnership Syringe pump
USD918396S1 (en) 2018-08-16 2021-05-04 Deka Products Limited Partnership Central controller
USD954968S1 (en) 2018-08-16 2022-06-14 Deka Products Limited Partnership Central controller
USD914196S1 (en) * 2018-08-16 2021-03-23 Deka Products Limited Partnership Peristaltic pump
USD914197S1 (en) 2018-08-16 2021-03-23 Deka Products Limited Partnership Syringe pump
USD1021072S1 (en) 2018-08-16 2024-04-02 Deka Products Limited Partnership Syringe pump
USD1021073S1 (en) 2018-08-16 2024-04-02 Deka Products Limited Partnership Syringe pump
WO2020076917A1 (en) * 2018-10-09 2020-04-16 University Of Washington Integrated multi-medication treatment delivery system
CN114286703A (en) * 2019-08-30 2022-04-05 费森尤斯医疗保健控股公司 Multi-lumen tubing assembly for medical fluid pumping system
US11207452B2 (en) 2019-08-30 2021-12-28 Fresenius Medical Care Holdings, Inc. Multi-lumen tube assemblies for medical fluid pumping systems
WO2021041313A1 (en) * 2019-08-30 2021-03-04 Fresenius Medical Care Holdings, Inc. Multi-lumen tube assemblies for medical fluid pumping systems
WO2021072263A1 (en) * 2019-10-11 2021-04-15 Merit Medical Systems, Inc. Keyed fluid line connectors and methods
US11806506B2 (en) * 2020-06-01 2023-11-07 DASH Anesthesia Intravenous fluid delivery system and apparatus
USD978352S1 (en) 2020-10-28 2023-02-14 Smiths Medical Asd, Inc. Cartridge cap

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