US3557778A - Blood specimen collection assembly - Google Patents
Blood specimen collection assembly Download PDFInfo
- Publication number
- US3557778A US3557778A US776347A US3557778DA US3557778A US 3557778 A US3557778 A US 3557778A US 776347 A US776347 A US 776347A US 3557778D A US3557778D A US 3557778DA US 3557778 A US3557778 A US 3557778A
- Authority
- US
- United States
- Prior art keywords
- assembly
- receptacle
- fluid
- chamber
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/15003—Source of blood for venous or arterial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150221—Valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150259—Improved gripping, e.g. with high friction pattern or projections on the housing surface or an ergonometric shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150351—Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
- A61B5/150381—Design of piercing elements
- A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
- A61B5/150381—Design of piercing elements
- A61B5/150473—Double-ended needles, e.g. used with pre-evacuated sampling tubes
- A61B5/150496—Details of construction of hub, i.e. element used to attach the double-ended needle to a piercing device or sampling device
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
- A61B5/154—Devices using pre-evacuated means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/22—Valves or arrangement of valves
- A61M39/24—Check- or non-return valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/22—Valves or arrangement of valves
- A61M39/24—Check- or non-return valves
- A61M2039/242—Check- or non-return valves designed to open when a predetermined pressure or flow rate has been reached, e.g. check valve actuated by fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/22—Valves or arrangement of valves
- A61M39/24—Check- or non-return valves
- A61M2039/2473—Valve comprising a non-deformable, movable element, e.g. ball-valve, valve with movable stopper or reciprocating element
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/22—Valves or arrangement of valves
- A61M39/24—Check- or non-return valves
- A61M2039/2473—Valve comprising a non-deformable, movable element, e.g. ball-valve, valve with movable stopper or reciprocating element
- A61M2039/248—Ball-valve
Definitions
- a blood specimen collection assembly having a fluid inlet and a fluid outlet with valve means disposed within the assembly for movement to and from an open and closed position whereby to prevent the backflow of testing fluid from a specimen receptacle, which is coupled with the assembly, into the patients bloodstream during use of the assembly.
- the specimen receptacle is in the form of an evacuated container and is coupled with the collection assembly when the same is in use, the receptacle being in communication with the assembly to provide negative pressure through the assembly for opening the valve and withdrawing the specimen, the valve resuming its closed position upon filling of the receptacle.
- BLOOD SPECIMEN COLLECTION ASSEMBLY This invention relates to improvements in devices used for taking blood samples from patients, and more specifically, to a blood collection assembly having check valve means therein to prevent backflow of the blood specimen and testing solution into the bloodstream of the patient.
- blood specimencollection devices have been used in the past for obtaining a quantity of blood from the patient suitable for subsequent mixing with a test solution, such devices have generally been so constructed that after withdrawing the blood specimen in one container, it was then necessary to transfer the blood into another container carrying the test fluid. This process subjected the blood specimen to possible contamination from various sources and subsequently increased the changes of obtaining invalid results from the test.
- test fluid container In more recent times devices have been developed which combine the specimen container and the test fluid container into one unit such that the blood specimen, upon being withdrawn through a hollow needle inserted in the patients vein, flows directly into the container having the testing solution therein. The test is thus carried out without requiring that the blood be transferred from one container to another. Since the needle remains in the patients arm during mixing of the blood specimen with the test fluid, however, there is a very grave danger that some of the mixture may flow back into the vein before the needle can be removed. Oftentimes the test fluid is of such a nature that only a very small amount need be released into the bloodstream before causing serious damage or even death to the patient being examined.
- a primary object of the present invention is to provide a blood specimen collection assembly which includes an evacuated specimen receptacle normally containing an amount of testing fluid therein, which receptacle is adapted to directly receive the blood specimen withdrawn from the patient by the assembly, the assembly additionally including check valve means whereby to prevent baekflow of the blood and fluid mixture from the receptacle into the bloodstream of the patrent.
- Another important object of this invention is to provide a blood specimen collection assembly for communication with a specimen receptacle, the assembly having a body provided with a chamber therein, a hollow needle in communication with the chamber and extending from one end of the body for penetrating a vein of the patient, valve means within the chamber shiftable to and from an open and closed condition permitting inflow of blood through the needle and a fluid outlet whereby said assembly is placed in communication with said receptacle to permit blood to be drawn through said assembly by the negative pressure exerted from the receptacle through the assembly.
- Yet another object of the instant invention is the provision of a blood specimen collection assembly comprising a combination of components including check valve means within the body of the assembly, the check valve means having a ball adapted for a sealing the fluid inlet of the assembly against backflow and structure for spacing the ball from the fluid outlet during flow of blood through the assembly to the specimen receptacle.
- a yet further object of the present invention is to provide a blood specimen collection assembly wherein the blood specimen is withdrawn from the patient into the specimen receptacle by means of a negative pressure exerted through the assembly by virtue of said receptacle being evacuated, the negative pressure causing shifting movement of a check valve to initially permit inflow of blood into the assembly and therethrough into the receptacle, the check valve then being permitted to shift to a closed position whereby to preclude backflow of the blood and testing mixture into the vein of the patient.
- FIG. I is a fragmentary, elevational view partially in section and showing one form of the invention with a specimen receptacle and holder;
- FIG. 2 is an enlarged, fragmentary, substantially central sectional view thereof with the receptacle and holder removed;
- FIG. 3 is a sectional view taken along line 3 -3 of FIG. 2;
- FIG. 4 is a side elevational view of another form of the invention with the specimen receptacle and holder removed;
- FIG. 5 is an enlarged, fragmentary, substantially central sectional view of the assembly shown in FIG. 4;
- FIG. 6 is a sectional view taken along line 6 6 of FIG. 5.
- the blood specimen collection assembly 10 as illustrated in the embodiment of the invention shown in FIG. 1 includes, as
- a body 12 having coupled therewith a specimen receptacle 14, there being a holder I6 provided for said receptacle in order that the assembly 10 may be utilized in the manner hereinafter described.
- the body I2 is best illustrated in the sectional showing of FIG. 2 of the drawing, the same including a head 18 and a fitting 20, said head I8 and fitting 20 preferably being formed of compatible materials whereby the same may be fitted together in cooperating relationship whereby to define a chamber 22 therebetween, the forwardmost end of said chamber being defined by a conical sidewall 24 formed interiorly of head 18, the normally rearmost end of the chamber 22 being defined by a face 26 presented by an inner end of fitting 20.
- a fluid inlet passage 28 extends through head 18 and is in communication with chamber 22, there being a hollow needle 30 carried within and extending substantially outwardly from said passage 28, which needle is penetrated into the vein of the patient during utilization of the assembly I0.
- a fluid outlet passageway 32 is formed substantially centrally of fitting 20 and carries tubular member 34 which extends rearwardly or to the right of the assembly I0 viewing FIGS. 1 and 2.
- the chamber 22 has check valve means disposed therein, said check valve means including a shiftable ball 36 and a plurality of ball-supporting flutes 38 formed as a part of the face 26 of fitting 20.
- Said check valve means permits longitudinal shifting movement of the ball 36 within the passage from the full line position shown in FIG. 2 of the drawing wherein the ball is in sealing engagement with the sidewall 24 whereby to close fluid inlet needle 30 to the dotted line position of FIG. 2 wherein the ball 36 is in engagement with the outer inclined edges 40 of the flutes 38, such engagement spacing ball 36 from the mouth 42 of tubular outlet member 34 whereby blood may pass through said outlet tube 34 and into the specimen receptacle when the assembly 10 is utilized in the manner hereinafter described.
- specimen receptacle 14 which receptacle contains a predetermined amount of testing material in the nature of a suitable liquid or powder which is intended to react with the blood in a predeten'nined manner in order to indicate certain desired characteristics. It is important that the blood, when mixed with such testing material, not be permitted to flow back through assembly 10 and into the bloodstream of the patient whose blood is being tested.
- a negative pressure is drawn on the receptacle l4 and the open end thereof is tightly closed by a stopper 44 having a centrally disposed thin section 46, to the opposite end of receptacle 14 being permanently sealed inasmuch as the same is in the nature of a test tube or the like.
- the holder 16 which is tubular in nature, having an open right-hand end viewing FIG. 1 (not shown) is provided at its opposite end with a closure wall 48 having a central aperture 50 which is threaded to complementally engage the threads 52 carried exteriorly of fitting 20.
- holder 16 may be coupled with the assembly 10 by interengagement of the threads thereof and the receptacle 14 can then be telescoped into the holder 16, it
- holder 16 could be provided with a pair of oppositely disposed finger-engaging flanges (not shown) whereby to permit the user of the complete assembly to easily grasp the holder 16 and exert, as by pressing thereupon with his thumb, a longitudinally directed force upon the receptacle 14.
- a longitudinally directed force upon the receptacle 14.
- the patients arm is prepared as by placing a constricting band thereabout and a venipuncture is made below the band with the tip of needle 30.
- Receptacle 14 is then pushed further into the holder 16 thereby causing section 46 to be fully punctured by tubular member 34 and thereby place the evacuated receptacle 14 in communication with assembly through said member 34, chamber 22 and needle 30 and thus into communication with the vein of the patient.
- the evacuated nature of receptacle 14 causes the negative pressure therein to be created through the assembly 10 thereby shifting ball 36 from the full line to the dotted line position of FIG. 2, thence opening fluid inlet 56 of chamber 22 and permitting flow of blood through needle 30 into the chamber 22 and thence outwardly through mouth 42 into tubular member 34 and into the specimen receptacle 14 where it mixes with the testing material.
- the constricting band When receptacle [4 is sufficiently full of the blood specimen, the constricting band is released and the needle 30 removed from the vein of the patient, Release of the constricting band creates a negative pressure in the area above the band's former position and this pressure is transferred through the assembly 10.
- the negative pressure created by releasing the constricting band draws ball 36 toward wall 24 and thereby seals inlet 56, precluding backflow of the blood and testing material mixture into the vein of the patient.
- FIGS. 46 of the drawing is generally similar in nature to that of F lGS. ll-
- FIGS. 46 is likewise adapted to be coupled with a specimen receptacle and holder, although the same are not shown in FIGS. 46.
- an assembly H0 having a body 112 comprised of a head 118 and a fitting 120, the same being coupled together whereby to cooperated to define a chamber 122,
- fitting 120 the normally forwardmost portionof said chamber being defined by a conical sidewall 124 and the rearmost end of said chamber being defined by a face 126 of fitting 120.
- a passage 128 is provided through head 118 and receives a needle 130.
- fitting has a central passage 132 therethrough which carries a tubular member 134.
- Check valve means is disposed in the passage 122 and includes a shittable ball 136 which is movable between the full line and dotted line position of H0. 5.
- a coil spring I40 normally urges ball 136 toward sidewall 124 thereby closing the fluid inlet 156.
- the'ball When a negative pressure is exerted through the assembly 110 the'ball is caused to move from its dotted line position against spring 140 and toward the fluid outlet mouth 142, the ball being retained in a position spaced from said mouth by the spring 140, thereby permitting blood to flow through the assembly as by moving through needle 130, chamber 122 and tubular member 134 and thence into the specimen receptacle which has been suitably coupled with the assembly 110.
- the assembly safely and suffi ciently precludes any backflow of the blood and testing material into the blood stream of the patient inasmuch as the check valve means is positioned in the flow path ahead of the point of mixture of the blood with the testing material.
- a blood specimen collection assembly comprising:
- a body having a chamber provided with a fluid inlet at one end and a fluid outlet at the opposite end, said chamber having a conical sidewall adjacent said fluid inlet and a plurality of radially spaced flutes adjacent said fluid outlet, surrounding said outlet and extending into said chamber;
- a hollow needle extending from said one end of the body and in fluid eommunicationwith the chamber through said inlet;
- check valve means in said chamber to permit flow of fluid through said chamber in one direction only, said check valve means including a ball larger in diameter than said fluid inlet and shiftable from a position in engagement with said conical wall whereby to close said fluid inlet and a position supported by said flutes in spaced relationship from said fluid outlet whereby to permit flow of fluid-
Abstract
A blood specimen collection assembly having a fluid inlet and a fluid outlet with valve means disposed within the assembly for movement to and from an open and closed position whereby to prevent the backflow of testing fluid from a specimen receptacle, which is coupled with the assembly, into the patient''s bloodstream during use of the assembly. The specimen receptacle is in the form of an evacuated container and is coupled with the collection assembly when the same is in use, the receptacle being in communication with the assembly to provide negative pressure through the assembly for opening the valve and withdrawing the specimen, the valve resuming its closed position upon filling of the receptacle.
Description
United States Patent [72] lnventor Elbert L. Hughes Independence, M0. (358 California Ave., Aurora, 111., 60506) {21] Appl. No. 776,347 [22] Filed Nov. 18, 1968 Patented Jan. 26, 1971 [541 BLOOD SPECIMEN COLLECTION ASSEMBLY 1 Claim, 6 Drawing Figs.
1,363,128 12/1920 Kitaoka 128/218 Primary Examiner-Warner H. Camp Att0rney-Schmidt, Johnson, Hovey, Williams & Chase ABSTRACT: A blood specimen collection assembly having a fluid inlet and a fluid outlet with valve means disposed within the assembly for movement to and from an open and closed position whereby to prevent the backflow of testing fluid from a specimen receptacle, which is coupled with the assembly, into the patients bloodstream during use of the assembly. The specimen receptacle is in the form of an evacuated container and is coupled with the collection assembly when the same is in use, the receptacle being in communication with the assembly to provide negative pressure through the assembly for opening the valve and withdrawing the specimen, the valve resuming its closed position upon filling of the receptacle.
BLOOD SPECIMEN COLLECTION ASSEMBLY This invention relates to improvements in devices used for taking blood samples from patients, and more specifically, to a blood collection assembly having check valve means therein to prevent backflow of the blood specimen and testing solution into the bloodstream of the patient.
Although blood specimencollection devices have been used in the past for obtaining a quantity of blood from the patient suitable for subsequent mixing with a test solution, such devices have generally been so constructed that after withdrawing the blood specimen in one container, it was then necessary to transfer the blood into another container carrying the test fluid. This process subjected the blood specimen to possible contamination from various sources and subsequently increased the changes of obtaining invalid results from the test.
In more recent times devices have been developed which combine the specimen container and the test fluid container into one unit such that the blood specimen, upon being withdrawn through a hollow needle inserted in the patients vein, flows directly into the container having the testing solution therein. The test is thus carried out without requiring that the blood be transferred from one container to another. Since the needle remains in the patients arm during mixing of the blood specimen with the test fluid, however, there is a very grave danger that some of the mixture may flow back into the vein before the needle can be removed. Oftentimes the test fluid is of such a nature that only a very small amount need be released into the bloodstream before causing serious damage or even death to the patient being examined.
A primary object of the present invention is to provide a blood specimen collection assembly which includes an evacuated specimen receptacle normally containing an amount of testing fluid therein, which receptacle is adapted to directly receive the blood specimen withdrawn from the patient by the assembly, the assembly additionally including check valve means whereby to prevent baekflow of the blood and fluid mixture from the receptacle into the bloodstream of the patrent.
Another important object of this invention is to provide a blood specimen collection assembly for communication with a specimen receptacle, the assembly having a body provided with a chamber therein, a hollow needle in communication with the chamber and extending from one end of the body for penetrating a vein of the patient, valve means within the chamber shiftable to and from an open and closed condition permitting inflow of blood through the needle and a fluid outlet whereby said assembly is placed in communication with said receptacle to permit blood to be drawn through said assembly by the negative pressure exerted from the receptacle through the assembly.
Yet another object of the instant invention is the provision of a blood specimen collection assembly comprising a combination of components including check valve means within the body of the assembly, the check valve means having a ball adapted for a sealing the fluid inlet of the assembly against backflow and structure for spacing the ball from the fluid outlet during flow of blood through the assembly to the specimen receptacle.
A yet further object of the present invention is to provide a blood specimen collection assembly wherein the blood specimen is withdrawn from the patient into the specimen receptacle by means of a negative pressure exerted through the assembly by virtue of said receptacle being evacuated, the negative pressure causing shifting movement of a check valve to initially permit inflow of blood into the assembly and therethrough into the receptacle, the check valve then being permitted to shift to a closed position whereby to preclude backflow of the blood and testing mixture into the vein of the patient.
Other objects of this invention include many details of construction which will become apparent from following specification and accompanying drawing, wherein:
FIG. I is a fragmentary, elevational view partially in section and showing one form of the invention with a specimen receptacle and holder;
FIG. 2 is an enlarged, fragmentary, substantially central sectional view thereof with the receptacle and holder removed;
FIG. 3 is a sectional view taken along line 3 -3 of FIG. 2;
FIG. 4 is a side elevational view of another form of the invention with the specimen receptacle and holder removed;
FIG. 5 is an enlarged, fragmentary, substantially central sectional view of the assembly shown in FIG. 4; and
FIG. 6 is a sectional view taken along line 6 6 of FIG. 5.
The blood specimen collection assembly 10 as illustrated in the embodiment of the invention shown in FIG. 1 includes, as
its primary components, a body 12 having coupled therewith a specimen receptacle 14, there being a holder I6 provided for said receptacle in order that the assembly 10 may be utilized in the manner hereinafter described.
The body I2 is best illustrated in the sectional showing of FIG. 2 of the drawing, the same including a head 18 and a fitting 20, said head I8 and fitting 20 preferably being formed of compatible materials whereby the same may be fitted together in cooperating relationship whereby to define a chamber 22 therebetween, the forwardmost end of said chamber being defined by a conical sidewall 24 formed interiorly of head 18, the normally rearmost end of the chamber 22 being defined by a face 26 presented by an inner end of fitting 20.
A fluid inlet passage 28 extends through head 18 and is in communication with chamber 22, there being a hollow needle 30 carried within and extending substantially outwardly from said passage 28, which needle is penetrated into the vein of the patient during utilization of the assembly I0.
A fluid outlet passageway 32 is formed substantially centrally of fitting 20 and carries tubular member 34 which extends rearwardly or to the right of the assembly I0 viewing FIGS. 1 and 2.
In the embodiment of the invention illustrated in FIGS. 1- 3, the chamber 22 has check valve means disposed therein, said check valve means including a shiftable ball 36 and a plurality of ball-supporting flutes 38 formed as a part of the face 26 of fitting 20. Said check valve means permits longitudinal shifting movement of the ball 36 within the passage from the full line position shown in FIG. 2 of the drawing wherein the ball is in sealing engagement with the sidewall 24 whereby to close fluid inlet needle 30 to the dotted line position of FIG. 2 wherein the ball 36 is in engagement with the outer inclined edges 40 of the flutes 38, such engagement spacing ball 36 from the mouth 42 of tubular outlet member 34 whereby blood may pass through said outlet tube 34 and into the specimen receptacle when the assembly 10 is utilized in the manner hereinafter described.
In order to permit such utilization of the assembly 10 the same is normally coupled with specimen receptacle 14, which receptacle contains a predetermined amount of testing material in the nature of a suitable liquid or powder which is intended to react with the blood in a predeten'nined manner in order to indicate certain desired characteristics. It is important that the blood, when mixed with such testing material, not be permitted to flow back through assembly 10 and into the bloodstream of the patient whose blood is being tested. In order to achievethis result, a negative pressure is drawn on the receptacle l4 and the open end thereof is tightly closed by a stopper 44 having a centrally disposed thin section 46, to the opposite end of receptacle 14 being permanently sealed inasmuch as the same is in the nature of a test tube or the like.
In order to permit utilization of the assembly 10, the holder 16, which is tubular in nature, having an open right-hand end viewing FIG. 1 (not shown) is provided at its opposite end with a closure wall 48 having a central aperture 50 which is threaded to complementally engage the threads 52 carried exteriorly of fitting 20. Thus, holder 16 may be coupled with the assembly 10 by interengagement of the threads thereof and the receptacle 14 can then be telescoped into the holder 16, it
being noted that holder 16 could be provided with a pair of oppositely disposed finger-engaging flanges (not shown) whereby to permit the user of the complete assembly to easily grasp the holder 16 and exert, as by pressing thereupon with his thumb, a longitudinally directed force upon the receptacle 14. When such force is directed against the receptacle 14, the same, as it is being telescoped into the holder 16, will cause the central section 46 of stopper 44 to move into initial engagement with the sharpened end 54 of the tubular outlet member 34 whereby to cause end 54 to slightly penetrate section 46.
When the assembly has been prepared as by bringing the various components into the relative engagement hereinabove described, the patients arm is prepared as by placing a constricting band thereabout and a venipuncture is made below the band with the tip of needle 30. Receptacle 14 is then pushed further into the holder 16 thereby causing section 46 to be fully punctured by tubular member 34 and thereby place the evacuated receptacle 14 in communication with assembly through said member 34, chamber 22 and needle 30 and thus into communication with the vein of the patient. The evacuated nature of receptacle 14 causes the negative pressure therein to be created through the assembly 10 thereby shifting ball 36 from the full line to the dotted line position of FIG. 2, thence opening fluid inlet 56 of chamber 22 and permitting flow of blood through needle 30 into the chamber 22 and thence outwardly through mouth 42 into tubular member 34 and into the specimen receptacle 14 where it mixes with the testing material.
When receptacle [4 is sufficiently full of the blood specimen, the constricting band is released and the needle 30 removed from the vein of the patient, Release of the constricting band creates a negative pressure in the area above the band's former position and this pressure is transferred through the assembly 10. In the past, when collection devices of this nature were not provided with any check valve means, it was a simple matter to accidentally allow some of the blood and testing material mixture to be drawn back through the assembly and into the patient's bloodstream under the negative vein pressure, often resulting in serious illness or death. With the present invention, however, the negative pressure created by releasing the constricting band draws ball 36 toward wall 24 and thereby seals inlet 56, precluding backflow of the blood and testing material mixture into the vein of the patient.
The embodiment of the invention illustrated in FIGS. 46 of the drawing is generally similar in nature to that of F lGS. ll-
3 and is likewise adapted to be coupled with a specimen receptacle and holder, although the same are not shown in FIGS. 46.
Thus there is provided an assembly H0 having a body 112 comprised of a head 118 and a fitting 120, the same being coupled together whereby to cooperated to define a chamber 122,
the normally forwardmost portionof said chamber being defined by a conical sidewall 124 and the rearmost end of said chamber being defined by a face 126 of fitting 120. A passage 128 is provided through head 118 and receives a needle 130. Likewise, fitting has a central passage 132 therethrough which carries a tubular member 134.
Check valve means is disposed in the passage 122 and includes a shittable ball 136 which is movable between the full line and dotted line position of H0. 5. A coil spring I40 normally urges ball 136 toward sidewall 124 thereby closing the fluid inlet 156. When a negative pressure is exerted through the assembly 110 the'ball is caused to move from its dotted line position against spring 140 and toward the fluid outlet mouth 142, the ball being retained in a position spaced from said mouth by the spring 140, thereby permitting blood to flow through the assembly as by moving through needle 130, chamber 122 and tubular member 134 and thence into the specimen receptacle which has been suitably coupled with the assembly 110.
In either form of the invention the assembly safely and suffi ciently precludes any backflow of the blood and testing material into the blood stream of the patient inasmuch as the check valve means is positioned in the flow path ahead of the point of mixture of the blood with the testing material. Thus,
at any time that the constricting band about the patients arm is released, it will cause shifting movement of the ball to a closed, sealing condition thereby effectively and fully precluding the flow of any of the blood and testing material mixture back through the assembly from thespecimen receptacle 14 into the bloodstream of the patient.
lclaim:
l. A blood specimen collection assembly comprising:
a partially evacuated specimen receptacle;
a body having a chamber provided with a fluid inlet at one end and a fluid outlet at the opposite end, said chamber having a conical sidewall adjacent said fluid inlet and a plurality of radially spaced flutes adjacent said fluid outlet, surrounding said outlet and extending into said chamber;
a hollow needle extending from said one end of the body and in fluid eommunicationwith the chamber through said inlet;
a fitting closing said opposite end of the chamber and having said fluid outlet formed therein, said fluid outlet being in communication with said receptacle; and
check valve means in said chamber to permit flow of fluid through said chamber in one direction only, said check valve means including a ball larger in diameter than said fluid inlet and shiftable from a position in engagement with said conical wall whereby to close said fluid inlet and a position supported by said flutes in spaced relationship from said fluid outlet whereby to permit flow of fluid-
Claims (1)
1. A blood specimen collection assembly comprising: a partially evacuated specimen receptacle; a body having a chamber provided with a fluid inlet at one end and a fluid outlet at the opposite end, said chamber having a conical sidewall adjacent said fluid inlet and a plurality of radially spaced flutes adjacent said fluid outlet, surrounding said outlet and extending into said chamber; a hollow needle extending from said one end of the body and in fluid communication with the chamber through said inlet; a fitting closing said opposite end of the chamber and having said fluid outlet formed therein, said fluid outlet being in communication with said receptacle; and check valve means in said chamber to permit flow of fluid through said chamber in one direction only, said check valve means including a ball larger in diameter than said fluid inlet and shiftable from a position in engagement with said conical wall whereby to close said fluid inlet and a position supported by said flutes in spaced relationship from said fluid outlet whereby to permit flow of fluid through said chamber, out of said outlet and into said receptacle.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77634768A | 1968-11-18 | 1968-11-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
US3557778A true US3557778A (en) | 1971-01-26 |
Family
ID=25107134
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US776347A Expired - Lifetime US3557778A (en) | 1968-11-18 | 1968-11-18 | Blood specimen collection assembly |
Country Status (1)
Country | Link |
---|---|
US (1) | US3557778A (en) |
Cited By (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2332967A1 (en) * | 1972-06-29 | 1974-01-10 | Becton Dickinson Co | DEVICE FOR COLLECTING BLOOD SAMPLE |
DE2332133A1 (en) * | 1972-06-28 | 1974-01-10 | Becton Dickinson Co | CANNULA UNIT FOR COLLECTING BLOOD SAMPLE |
US3848579A (en) * | 1973-02-23 | 1974-11-19 | Real A Villa | Automatic elasto-valvular hypodermic sampling needle |
US3881448A (en) * | 1973-11-23 | 1975-05-06 | Olof A Hallstrom | Milking valve |
US3916894A (en) * | 1972-09-20 | 1975-11-04 | Nosco Plastics | Syringe seals and piston |
FR2333521A1 (en) * | 1975-12-03 | 1977-07-01 | Burron Medical Prod Inc | SYSTEM FOR THE ADMINISTRATION OF A PARENTERAL LIQUID |
US4245635A (en) * | 1979-01-29 | 1981-01-20 | Jelco Laboratories | Catheter assembly for intermittent intravenous use |
FR2477403A1 (en) * | 1980-03-10 | 1981-09-11 | Becton Dickinson Co | MULTIPLE SAMPLE PICKUP ASSEMBLY HAVING AN ANTI-DISCHARGE VALVE |
EP0051718A1 (en) * | 1980-11-08 | 1982-05-19 | Intermedicat Gmbh | Entering device for catheters |
US4333479A (en) * | 1979-10-01 | 1982-06-08 | Shiplee Iii Lewis D | Disposable needle assembly |
US4349035A (en) * | 1978-03-14 | 1982-09-14 | Johnson & Johnson | Blood collection assembly with unidirectional flow valve |
US4481008A (en) * | 1981-10-08 | 1984-11-06 | Bioresearch Inc. | Apparatus and method for relieving excess negativity in a drainage device |
FR2563990A1 (en) * | 1984-05-10 | 1985-11-15 | Labarthe Jean | Instrument for taking small quantities of blood |
US4732162A (en) * | 1985-10-18 | 1988-03-22 | Martell Medical Products, Inc. | Automatic and position-sensitive syringe and method for nonaspirating or aspirating obtaining of blood samples |
DE8703971U1 (en) * | 1987-03-17 | 1988-07-21 | Ballies, Uwe, Dr. Med., 2300 Kiel, De | |
US4857061A (en) * | 1988-04-15 | 1989-08-15 | Miller Michael D | Single-flow valve-hypodermic needle combination |
EP0335840A2 (en) * | 1988-03-30 | 1989-10-04 | Urbano Barbabella | A gravity valve device to prevent liquids from draining completely out of vessels |
WO1989010723A1 (en) * | 1988-05-02 | 1989-11-16 | Nielsen Bjoern | A blood sampling equipment with needle, holder and vacuum vial |
FR2636537A1 (en) * | 1988-09-16 | 1990-03-23 | Garde Claude | Suction and withdrawal syringe |
US4915688A (en) * | 1987-12-03 | 1990-04-10 | Baxter International Inc. | Apparatus for administering solution to a patient |
WO1990003777A1 (en) * | 1988-10-14 | 1990-04-19 | Corpak, Inc. | Valve means for enteral therapy administration set |
US4973248A (en) * | 1988-12-09 | 1990-11-27 | Myron International, Inc. | Delivery system for dentinal/enamel adhesive materials |
US5167238A (en) * | 1991-05-02 | 1992-12-01 | Cobe Laboratories, Inc. | Fluid sampling device |
US5309924A (en) * | 1992-04-29 | 1994-05-10 | Peabody Alan M | Spill-proof blood collection device |
FR2735373A1 (en) * | 1995-06-16 | 1996-12-20 | Debiotech Sa | ANGIOPLASTY DEVICE |
WO1998007462A1 (en) * | 1996-08-20 | 1998-02-26 | Backes Claus H | Medical high-pressure injection system |
US5743883A (en) * | 1995-06-07 | 1998-04-28 | Visconti; Peter L. | Thoracentesis catheter instruments having self-sealing valves |
GB2327885A (en) * | 1997-08-02 | 1999-02-10 | Nmt Group Plc | Filling needle |
US6050957A (en) * | 1998-07-01 | 2000-04-18 | Desch; Larry W. | Multiple-draw, variable suction syringe |
US6217556B1 (en) | 1998-03-19 | 2001-04-17 | Allegiance Corporation | Drainage catheter |
US20020158083A1 (en) * | 1991-12-06 | 2002-10-31 | Brown Paul E. | Dispensing valve |
US20050101879A1 (en) * | 2003-11-06 | 2005-05-12 | Shidham Vinod B. | Needle aspiration biopsy device and method |
EP1614384A2 (en) * | 2004-07-09 | 2006-01-11 | Nipro Corporation | Blood collection needle |
US20060155213A1 (en) * | 2005-01-10 | 2006-07-13 | Madonia James R | Self flushing luer activated blood sampling devices |
US20090018174A1 (en) * | 2005-11-08 | 2009-01-15 | Pradip Kumar Bhatnagar | Macrolides as anti-inflammatory agents |
US20110190723A1 (en) * | 2006-04-12 | 2011-08-04 | Fangrow Thomas F | Pressure-regulating vials and containers |
US20110208160A1 (en) * | 2010-02-24 | 2011-08-25 | Becton, Dickinson And Company | Safety Drug Delivery System |
US20110208128A1 (en) * | 2010-02-24 | 2011-08-25 | Becton, Dickinson And Company | Safety Drug Delivery Connectors |
US8465461B2 (en) | 2010-07-27 | 2013-06-18 | Becton, Dickinson And Company | Blunt needle safety drug delivery system |
US20140074044A1 (en) * | 2011-05-06 | 2014-03-13 | Sanofi-Aventis Deutschland Gmbh | Needle Hub and Valve for Needle Hub |
US8968249B2 (en) | 2002-05-10 | 2015-03-03 | Covidien Lp | Introducer seal assembly |
US9089475B2 (en) | 2013-01-23 | 2015-07-28 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
CN104826178A (en) * | 2010-03-12 | 2015-08-12 | 凯希特许有限公司 | Reduced-pressure dressing connection pads, systems, and methods |
US9107808B2 (en) | 2007-03-09 | 2015-08-18 | Icu Medical, Inc. | Adaptors for removing medicinal fluids from a container |
US9132062B2 (en) | 2011-08-18 | 2015-09-15 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US20150351728A1 (en) * | 2013-01-09 | 2015-12-10 | Floyd Nathan Stewart | Urine sample device |
CN105251115A (en) * | 2015-10-21 | 2016-01-20 | 深圳市安特高科实业有限公司 | Medical valve, medical communicating device and transfusion assembly |
US9351905B2 (en) | 2008-08-20 | 2016-05-31 | Icu Medical, Inc. | Anti-reflux vial adaptors |
US9610217B2 (en) | 2012-03-22 | 2017-04-04 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US9615997B2 (en) | 2013-01-23 | 2017-04-11 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US9987195B2 (en) | 2012-01-13 | 2018-06-05 | Icu Medical, Inc. | Pressure-regulating vial adaptors and methods |
US10201476B2 (en) | 2014-06-20 | 2019-02-12 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US10292904B2 (en) | 2016-01-29 | 2019-05-21 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US11504302B2 (en) | 2013-07-19 | 2022-11-22 | Icu Medical, Inc. | Pressure-regulating fluid transfer systems and methods |
US11744775B2 (en) | 2016-09-30 | 2023-09-05 | Icu Medical, Inc. | Pressure-regulating vial access devices and methods |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1174673A (en) * | 1915-09-10 | 1916-03-07 | Lilly Co Eli | Syringe. |
US1174745A (en) * | 1915-03-11 | 1916-03-07 | Lilly Co Eli | Hypodermic syringe. |
US1363128A (en) * | 1920-02-11 | 1920-12-21 | Shigezo Nishitani | Injection-syringe |
US2102704A (en) * | 1935-06-10 | 1937-12-21 | George N Hein | Syringe cartridge |
US3123073A (en) * | 1964-03-03 | Blood sampling assembly | ||
US3382865A (en) * | 1965-10-18 | 1968-05-14 | Ashton L. Worrall Jr. | Device for taking multiple blood samples or the like |
-
1968
- 1968-11-18 US US776347A patent/US3557778A/en not_active Expired - Lifetime
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3123073A (en) * | 1964-03-03 | Blood sampling assembly | ||
US1174745A (en) * | 1915-03-11 | 1916-03-07 | Lilly Co Eli | Hypodermic syringe. |
US1174673A (en) * | 1915-09-10 | 1916-03-07 | Lilly Co Eli | Syringe. |
US1363128A (en) * | 1920-02-11 | 1920-12-21 | Shigezo Nishitani | Injection-syringe |
US2102704A (en) * | 1935-06-10 | 1937-12-21 | George N Hein | Syringe cartridge |
US3382865A (en) * | 1965-10-18 | 1968-05-14 | Ashton L. Worrall Jr. | Device for taking multiple blood samples or the like |
Cited By (117)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2332133A1 (en) * | 1972-06-28 | 1974-01-10 | Becton Dickinson Co | CANNULA UNIT FOR COLLECTING BLOOD SAMPLE |
US3874367A (en) * | 1972-06-29 | 1975-04-01 | Becton Dickinson Co | Valved blood sampling needle assembly |
DE2332967A1 (en) * | 1972-06-29 | 1974-01-10 | Becton Dickinson Co | DEVICE FOR COLLECTING BLOOD SAMPLE |
US3916894A (en) * | 1972-09-20 | 1975-11-04 | Nosco Plastics | Syringe seals and piston |
US3848579A (en) * | 1973-02-23 | 1974-11-19 | Real A Villa | Automatic elasto-valvular hypodermic sampling needle |
US3881448A (en) * | 1973-11-23 | 1975-05-06 | Olof A Hallstrom | Milking valve |
FR2333521A1 (en) * | 1975-12-03 | 1977-07-01 | Burron Medical Prod Inc | SYSTEM FOR THE ADMINISTRATION OF A PARENTERAL LIQUID |
US4349035A (en) * | 1978-03-14 | 1982-09-14 | Johnson & Johnson | Blood collection assembly with unidirectional flow valve |
US4245635A (en) * | 1979-01-29 | 1981-01-20 | Jelco Laboratories | Catheter assembly for intermittent intravenous use |
US4333479A (en) * | 1979-10-01 | 1982-06-08 | Shiplee Iii Lewis D | Disposable needle assembly |
US4317456A (en) * | 1980-03-10 | 1982-03-02 | Becton, Dickinson And Company | Multiple sample needle with anti-backflow valve |
FR2477403A1 (en) * | 1980-03-10 | 1981-09-11 | Becton Dickinson Co | MULTIPLE SAMPLE PICKUP ASSEMBLY HAVING AN ANTI-DISCHARGE VALVE |
DE3103031A1 (en) * | 1980-03-10 | 1981-12-17 | Becton, Dickinson and Co., 07652 Paramus, N.J. | DEVICE FOR TAKING BODY LIQUIDS |
EP0051718A1 (en) * | 1980-11-08 | 1982-05-19 | Intermedicat Gmbh | Entering device for catheters |
US4481008A (en) * | 1981-10-08 | 1984-11-06 | Bioresearch Inc. | Apparatus and method for relieving excess negativity in a drainage device |
FR2563990A1 (en) * | 1984-05-10 | 1985-11-15 | Labarthe Jean | Instrument for taking small quantities of blood |
US4732162A (en) * | 1985-10-18 | 1988-03-22 | Martell Medical Products, Inc. | Automatic and position-sensitive syringe and method for nonaspirating or aspirating obtaining of blood samples |
DE8703971U1 (en) * | 1987-03-17 | 1988-07-21 | Ballies, Uwe, Dr. Med., 2300 Kiel, De | |
US4915688A (en) * | 1987-12-03 | 1990-04-10 | Baxter International Inc. | Apparatus for administering solution to a patient |
EP0335840A2 (en) * | 1988-03-30 | 1989-10-04 | Urbano Barbabella | A gravity valve device to prevent liquids from draining completely out of vessels |
EP0335840A3 (en) * | 1988-03-30 | 1990-01-31 | Urbano Barbabella | A gravity valve device to prevent liquids from draining completely out of vessels |
US4857061A (en) * | 1988-04-15 | 1989-08-15 | Miller Michael D | Single-flow valve-hypodermic needle combination |
WO1989010723A1 (en) * | 1988-05-02 | 1989-11-16 | Nielsen Bjoern | A blood sampling equipment with needle, holder and vacuum vial |
AU618603B2 (en) * | 1988-05-02 | 1992-01-02 | Bjorn Nielsen | A blood sampling equipment with needle, holder and vacuum vial |
FR2636537A1 (en) * | 1988-09-16 | 1990-03-23 | Garde Claude | Suction and withdrawal syringe |
WO1990003777A1 (en) * | 1988-10-14 | 1990-04-19 | Corpak, Inc. | Valve means for enteral therapy administration set |
US4973248A (en) * | 1988-12-09 | 1990-11-27 | Myron International, Inc. | Delivery system for dentinal/enamel adhesive materials |
US5167238A (en) * | 1991-05-02 | 1992-12-01 | Cobe Laboratories, Inc. | Fluid sampling device |
US5301686A (en) * | 1991-05-02 | 1994-04-12 | Cobe Laboratories, Inc. | Fluid sampling method |
US20020158083A1 (en) * | 1991-12-06 | 2002-10-31 | Brown Paul E. | Dispensing valve |
US5309924A (en) * | 1992-04-29 | 1994-05-10 | Peabody Alan M | Spill-proof blood collection device |
US5743883A (en) * | 1995-06-07 | 1998-04-28 | Visconti; Peter L. | Thoracentesis catheter instruments having self-sealing valves |
FR2735373A1 (en) * | 1995-06-16 | 1996-12-20 | Debiotech Sa | ANGIOPLASTY DEVICE |
WO1997000093A1 (en) * | 1995-06-16 | 1997-01-03 | Debiotech S.A. | Angioplasty device |
WO1998007462A1 (en) * | 1996-08-20 | 1998-02-26 | Backes Claus H | Medical high-pressure injection system |
GB2327885A (en) * | 1997-08-02 | 1999-02-10 | Nmt Group Plc | Filling needle |
US6217556B1 (en) | 1998-03-19 | 2001-04-17 | Allegiance Corporation | Drainage catheter |
US6050957A (en) * | 1998-07-01 | 2000-04-18 | Desch; Larry W. | Multiple-draw, variable suction syringe |
US8968249B2 (en) | 2002-05-10 | 2015-03-03 | Covidien Lp | Introducer seal assembly |
US20050101879A1 (en) * | 2003-11-06 | 2005-05-12 | Shidham Vinod B. | Needle aspiration biopsy device and method |
US20060009714A1 (en) * | 2004-07-09 | 2006-01-12 | Yoshio Higaki | Blood collection needle |
JP2006020934A (en) * | 2004-07-09 | 2006-01-26 | Nipro Corp | Blood collection needle |
EP1614384A3 (en) * | 2004-07-09 | 2006-03-22 | Nipro Corporation | Blood collection needle |
US7267653B2 (en) | 2004-07-09 | 2007-09-11 | Nipro Corporation | Blood collection needle |
EP1614384A2 (en) * | 2004-07-09 | 2006-01-11 | Nipro Corporation | Blood collection needle |
US20060155213A1 (en) * | 2005-01-10 | 2006-07-13 | Madonia James R | Self flushing luer activated blood sampling devices |
US7314452B2 (en) * | 2005-01-10 | 2008-01-01 | Edwards Lifesciences Corporation | Self flushing luer activated blood sampling devices |
US20080064985A1 (en) * | 2005-01-10 | 2008-03-13 | Madonia James R | Self flushing luer activated blood sampling devices |
US7963950B2 (en) | 2005-01-10 | 2011-06-21 | Edwards Lifesciences Corporation | Self flushing luer activated blood sampling devices |
US20090018174A1 (en) * | 2005-11-08 | 2009-01-15 | Pradip Kumar Bhatnagar | Macrolides as anti-inflammatory agents |
US8945084B2 (en) | 2006-04-12 | 2015-02-03 | Icu Medical, Inc. | Pressure-regulating vial adaptors and methods |
US9060921B2 (en) | 2006-04-12 | 2015-06-23 | Icu Medical, Inc. | Air-filtering vial adaptors and methods |
US9993391B2 (en) | 2006-04-12 | 2018-06-12 | Icu Medical, Inc. | Devices and methods for transferring medicinal fluid to or from a container |
US9993390B2 (en) | 2006-04-12 | 2018-06-12 | Icu Medical, Inc. | Pressure-regulating vial adaptors and methods |
US11696871B2 (en) | 2006-04-12 | 2023-07-11 | Icu Medical, Inc. | Devices for accessing medicinal fluid from a container |
US11013664B2 (en) | 2006-04-12 | 2021-05-25 | Icu Medical, Inc. | Devices for transferring fluid to or from a vial |
US8882738B2 (en) | 2006-04-12 | 2014-11-11 | Icu Medical, Inc. | Locking vial adaptors and methods |
US10022302B2 (en) | 2006-04-12 | 2018-07-17 | Icu Medical, Inc. | Devices for transferring medicinal fluids to or from a container |
US20110190723A1 (en) * | 2006-04-12 | 2011-08-04 | Fangrow Thomas F | Pressure-regulating vials and containers |
US8974433B2 (en) | 2006-04-12 | 2015-03-10 | Icu Medical, Inc. | Pressure-regulating vials and containers |
US8992501B2 (en) | 2006-04-12 | 2015-03-31 | Icu Medical, Inc. | Pressure-regulating vial adaptors and methods |
US9005179B2 (en) | 2006-04-12 | 2015-04-14 | Icu Medical, Inc. | Pressure-regulating apparatus for withdrawing medicinal fluid from a vial |
US9005180B2 (en) | 2006-04-12 | 2015-04-14 | Icu Medical, Inc. | Vial adaptors and methods for regulating pressure |
US10492993B2 (en) | 2006-04-12 | 2019-12-03 | Icu Medical, Inc. | Vial access devices and methods |
US10071020B2 (en) | 2006-04-12 | 2018-09-11 | Icu Medical, Inc. | Devices for transferring fluid to or from a vial |
US9662272B2 (en) | 2006-04-12 | 2017-05-30 | Icu Medical, Inc. | Devices and methods for transferring fluid to or from a vial |
US9072657B2 (en) | 2006-04-12 | 2015-07-07 | Icu Medical, Inc. | Pressure-regulating vial adaptors and methods |
US10327992B2 (en) | 2006-04-12 | 2019-06-25 | Icu Medical, Inc. | Fluid transfer apparatus with pressure regulation |
US10327989B2 (en) | 2006-04-12 | 2019-06-25 | Icu Medical, Inc. | Devices and methods for transferring fluid to or from a vial |
US10327993B2 (en) | 2006-04-12 | 2019-06-25 | Icu Medical, Inc. | Vial access devices |
US10327991B2 (en) | 2006-04-12 | 2019-06-25 | Icu Medical, Inc. | Fluid transfer apparatus with filtered air input |
US9107808B2 (en) | 2007-03-09 | 2015-08-18 | Icu Medical, Inc. | Adaptors for removing medicinal fluids from a container |
US9351905B2 (en) | 2008-08-20 | 2016-05-31 | Icu Medical, Inc. | Anti-reflux vial adaptors |
US9931275B2 (en) | 2008-08-20 | 2018-04-03 | Icu Medical, Inc. | Anti-reflux vial adaptors |
CN102844073B (en) * | 2010-02-24 | 2015-11-25 | 贝克顿·迪金森公司 | A kind of drug conveying adapter |
US9205248B2 (en) * | 2010-02-24 | 2015-12-08 | Becton, Dickinson And Company | Safety Drug delivery connectors |
US20110208128A1 (en) * | 2010-02-24 | 2011-08-25 | Becton, Dickinson And Company | Safety Drug Delivery Connectors |
US9056163B2 (en) | 2010-02-24 | 2015-06-16 | Becton, Dickinson And Company | Safety drug delivery system |
US20110208160A1 (en) * | 2010-02-24 | 2011-08-25 | Becton, Dickinson And Company | Safety Drug Delivery System |
US9381339B2 (en) | 2010-02-24 | 2016-07-05 | Becton, Dickinson And Company | Safety drug delivery connectors |
CN102844073A (en) * | 2010-02-24 | 2012-12-26 | 贝克顿·迪金森公司 | Safety drug delivery connectors |
WO2011106374A1 (en) * | 2010-02-24 | 2011-09-01 | Becton, Dickinson And Company | Safety drug delivery connectors |
CN104826178A (en) * | 2010-03-12 | 2015-08-12 | 凯希特许有限公司 | Reduced-pressure dressing connection pads, systems, and methods |
US9427502B2 (en) | 2010-03-12 | 2016-08-30 | Kci Licensing, Inc. | Reduced-pressure dressing connection pads, systems, and methods |
US10556044B2 (en) | 2010-03-12 | 2020-02-11 | Kci Licensing, Inc. | Reduced-pressure dressing connection pads, systems, and methods |
EP2921199A1 (en) * | 2010-03-12 | 2015-09-23 | KCI Licensing Inc. | Reduced-pressure dressing connection pads, systems, and methods |
CN104826178B (en) * | 2010-03-12 | 2018-05-04 | 凯希特许有限公司 | Reduced-pressure dressings connection gasket, system and method |
US8465461B2 (en) | 2010-07-27 | 2013-06-18 | Becton, Dickinson And Company | Blunt needle safety drug delivery system |
US9044554B2 (en) | 2010-07-27 | 2015-06-02 | Becton, Dickinson And Company | Blunt needle safety drug delivery system |
US9345845B2 (en) * | 2011-05-06 | 2016-05-24 | Sanofi-Aventis Deutschland Gmbh | Needle hub and valve for needle hub |
US20140074044A1 (en) * | 2011-05-06 | 2014-03-13 | Sanofi-Aventis Deutschland Gmbh | Needle Hub and Valve for Needle Hub |
US10688022B2 (en) | 2011-08-18 | 2020-06-23 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US11672734B2 (en) | 2011-08-18 | 2023-06-13 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US9895291B2 (en) | 2011-08-18 | 2018-02-20 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US11129773B2 (en) | 2011-08-18 | 2021-09-28 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US9132062B2 (en) | 2011-08-18 | 2015-09-15 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US9987195B2 (en) | 2012-01-13 | 2018-06-05 | Icu Medical, Inc. | Pressure-regulating vial adaptors and methods |
US9610217B2 (en) | 2012-03-22 | 2017-04-04 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US10299989B2 (en) | 2012-03-22 | 2019-05-28 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US11185471B2 (en) | 2012-03-22 | 2021-11-30 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US11654086B2 (en) | 2012-03-22 | 2023-05-23 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US10918573B2 (en) | 2012-03-22 | 2021-02-16 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US20150351728A1 (en) * | 2013-01-09 | 2015-12-10 | Floyd Nathan Stewart | Urine sample device |
US9089475B2 (en) | 2013-01-23 | 2015-07-28 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US9615997B2 (en) | 2013-01-23 | 2017-04-11 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US9763855B2 (en) | 2013-01-23 | 2017-09-19 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US10806672B2 (en) | 2013-01-23 | 2020-10-20 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US11857499B2 (en) | 2013-01-23 | 2024-01-02 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US10117807B2 (en) | 2013-01-23 | 2018-11-06 | Icu Medical, Inc. | Pressure-regulating devices for transferring medicinal fluid |
US11504302B2 (en) | 2013-07-19 | 2022-11-22 | Icu Medical, Inc. | Pressure-regulating fluid transfer systems and methods |
US11648181B2 (en) | 2013-07-19 | 2023-05-16 | Icu Medical, Inc. | Pressure-regulating fluid transfer systems and methods |
US10987277B2 (en) | 2014-06-20 | 2021-04-27 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US10201476B2 (en) | 2014-06-20 | 2019-02-12 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
CN105251115A (en) * | 2015-10-21 | 2016-01-20 | 深圳市安特高科实业有限公司 | Medical valve, medical communicating device and transfusion assembly |
US10292904B2 (en) | 2016-01-29 | 2019-05-21 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US11529289B2 (en) | 2016-01-29 | 2022-12-20 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
US11744775B2 (en) | 2016-09-30 | 2023-09-05 | Icu Medical, Inc. | Pressure-regulating vial access devices and methods |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US3557778A (en) | Blood specimen collection assembly | |
US3464412A (en) | Intermixing syringe | |
US3874367A (en) | Valved blood sampling needle assembly | |
US3411503A (en) | Collapsible mixing syringe with extrusion casing | |
US3494351A (en) | Multiple vial fluid collecting device | |
US3200813A (en) | Aspirating syringes | |
US3494352A (en) | Apparatus for taking multiple samples | |
US4312362A (en) | Single sample needle with vein entry indicator | |
US5295970A (en) | Apparatus and method for vascular guide wire insertion with blood flashback containment features | |
US4266559A (en) | Blood sampler | |
US3996923A (en) | Blood taking device | |
US4943283A (en) | Blood collecting apparatus with shielded needles | |
US3817240A (en) | Multiple sample needle assembly with one-way valve and blood flow indicator | |
US3753432A (en) | Hypodermic syringe for blood tests | |
US3712295A (en) | Centrifuge tube | |
US5947932A (en) | Closed system blood sampling device | |
US3460529A (en) | Sterile device for extracting urine samples and the like and package for same | |
US3734079A (en) | Apparatus for blood tests | |
US2519555A (en) | Sterile medicament insufflator cartridge and insufflator | |
US3595217A (en) | Fine needle aspiration biopsy of prostate | |
EP0017728A3 (en) | Blood letting instrument with blood sampling cannula and method of evacuating the cannula | |
US3566859A (en) | Vacuum syringe | |
US3308809A (en) | Blood withdrawal device and dispenser | |
US3162195A (en) | Vacuated body fluid collection vial | |
US2437381A (en) | Embalming appliance |