DE69818294D1 - Oxazolidinone derivate und pharmazeutische zusammensetzungen - Google Patents

Oxazolidinone derivate und pharmazeutische zusammensetzungen

Info

Publication number
DE69818294D1
DE69818294D1 DE69818294T DE69818294T DE69818294D1 DE 69818294 D1 DE69818294 D1 DE 69818294D1 DE 69818294 T DE69818294 T DE 69818294T DE 69818294 T DE69818294 T DE 69818294T DE 69818294 D1 DE69818294 D1 DE 69818294D1
Authority
DE
Germany
Prior art keywords
pharmaceutical compositions
oxazolidinone derivatives
organisms
compound
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69818294T
Other languages
English (en)
Other versions
DE69818294T2 (de
Inventor
B Hester
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Application granted granted Critical
Publication of DE69818294D1 publication Critical patent/DE69818294D1/de
Publication of DE69818294T2 publication Critical patent/DE69818294T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
DE69818294T 1997-11-12 1998-10-30 Oxazolidinone derivate und pharmazeutische zusammensetzungen Expired - Fee Related DE69818294T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6537697P 1997-11-12 1997-11-12
US65376P 1997-11-12
PCT/US1998/022639 WO1999024428A1 (en) 1997-11-12 1998-10-30 Oxazolidinone derivatives and pharmaceutical compositions

Publications (2)

Publication Number Publication Date
DE69818294D1 true DE69818294D1 (de) 2003-10-23
DE69818294T2 DE69818294T2 (de) 2004-07-08

Family

ID=22062294

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69818294T Expired - Fee Related DE69818294T2 (de) 1997-11-12 1998-10-30 Oxazolidinone derivate und pharmazeutische zusammensetzungen

Country Status (22)

Country Link
US (1) US5998406A (de)
EP (1) EP1030852B1 (de)
JP (1) JP2001522849A (de)
KR (1) KR20010031953A (de)
CN (1) CN1154644C (de)
AT (1) ATE250054T1 (de)
AU (1) AU739055B2 (de)
BR (1) BR9813985A (de)
CA (1) CA2303959A1 (de)
DE (1) DE69818294T2 (de)
DK (1) DK1030852T3 (de)
ES (1) ES2207010T3 (de)
HK (1) HK1030373A1 (de)
HU (1) HUP0100470A3 (de)
IL (1) IL136062A (de)
NO (1) NO317291B1 (de)
NZ (1) NZ504503A (de)
PT (1) PT1030852E (de)
RU (1) RU2215740C2 (de)
SK (1) SK284577B6 (de)
TR (1) TR200001330T2 (de)
WO (1) WO1999024428A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE200000707A (et) 1998-06-05 2002-04-15 Astrazeneca Ab Oksasolidinooni derivaadid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
KR100355345B1 (ko) * 2000-01-21 2002-10-12 한국과학기술연구원 티오펜환을 함유한 신규한 옥사졸리디논 유도체, 그의 제조방법 및 조성물
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
EP1539745B1 (de) * 2002-08-12 2006-03-29 Pharmacia & Upjohn Company LLC N-aryl-2-oxazolidinone und deren derivate
DE10300111A1 (de) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
BRPI0413838A (pt) * 2003-08-25 2006-10-24 Warner Lambert Co compostos de ariloxazolidinona antimicrobianos
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
WO2006056877A2 (en) * 2004-11-29 2006-06-01 Pharmacia & Upjohn Company Llc Diazepine oxazolidinones as antibacterial agents
DE102004062475A1 (de) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung
EP1685841A1 (de) * 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prophylaxe und Behandlung von thrombolischen Erkrankungen
ES2335307T3 (es) 2005-06-29 2010-03-24 PHARMACIA & UPJOHN COMPANY LLC Homomorfolin oxalidinonas como agentes antibacterianos.
DE102005045518A1 (de) 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
RU2429236C2 (ru) 2005-10-04 2011-09-20 Байер Шеринг Фарма Акциенгезельшафт Новая полиморфная форма и аморфная форма 5-хлор-n-({(5s)-2-оксо-3-[4-(3-оксо-4-морфолинил)-фенил]-1, 3-оксазолидин-5-ил}-метил)-2-тиофенкарбоксамида
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
DE102005047558A1 (de) * 2005-10-04 2008-02-07 Bayer Healthcare Ag Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen
TW200804358A (en) 2006-03-31 2008-01-16 Res Found Itsuu Lab Novel compound having heterocycle
JPWO2009044777A1 (ja) * 2007-10-02 2011-02-10 財団法人乙卯研究所 ７員ヘテロ環を有するオキサゾリジノン誘導体
WO2012059823A1 (en) 2010-11-03 2012-05-10 Wockhardt Limited Process for the preparation of phosphoric acid mono- (l-{4- [(s) -5- (acetylaminomethyl) - 2 - oxo - oxazolidin- 3 - yl] - 2, 6 - difluorophenyl} - 4 -methoxymethylpiperidin- 4 - yl) ester
WO2015173664A1 (en) 2014-05-14 2015-11-19 Wockhardt Limited Process for the preparation of (5s)-n-{3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801600A (en) * 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
CA1320730C (en) * 1987-10-16 1993-07-27 The Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
DE3884563T2 (de) * 1987-10-21 1994-02-17 Du Pont Merck Pharma Aminomethyl-oxo-oxazolidinyl-ethenylbenzen-Derivate, nützlich als antibakterielles Mittel.
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
DE68929303T2 (de) * 1988-09-15 2002-05-02 Upjohn Co 3-(Stickstoff substituierte)phenyl-5-beta-amidomethyloxazoliden-2-one
WO1993009103A1 (en) * 1991-11-01 1993-05-13 The Upjohn Company Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
AU698699B2 (en) * 1993-11-22 1998-11-05 Pharmacia & Upjohn Company Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones
JPH0873455A (ja) * 1994-03-15 1996-03-19 Upjohn Co:The オキサゾリジノン誘導体及びこれを有効成分とする医薬組成物
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
NO20002434L (no) 2000-05-11
BR9813985A (pt) 2000-09-26
ES2207010T3 (es) 2004-05-16
SK284577B6 (sk) 2005-07-01
DE69818294T2 (de) 2004-07-08
ATE250054T1 (de) 2003-10-15
CN1154644C (zh) 2004-06-23
NZ504503A (en) 2002-10-25
PT1030852E (pt) 2004-02-27
CA2303959A1 (en) 1999-05-20
IL136062A (en) 2004-02-08
HUP0100470A2 (hu) 2002-05-29
SK6182000A3 (en) 2000-12-11
IL136062A0 (en) 2001-05-20
KR20010031953A (ko) 2001-04-16
HUP0100470A3 (en) 2002-08-28
WO1999024428A1 (en) 1999-05-20
NO20002434D0 (no) 2000-05-11
EP1030852A1 (de) 2000-08-30
TR200001330T2 (tr) 2000-11-21
NO317291B1 (no) 2004-10-04
CN1271358A (zh) 2000-10-25
HK1030373A1 (en) 2001-05-04
US5998406A (en) 1999-12-07
JP2001522849A (ja) 2001-11-20
RU2215740C2 (ru) 2003-11-10
AU1277899A (en) 1999-05-31
DK1030852T3 (da) 2003-12-22
AU739055B2 (en) 2001-10-04
EP1030852B1 (de) 2003-09-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee