DE69717630T2 - 3-phenyl-furan-(5h)-2-on- und dihydrofuran-2-on-derivate als antibakterielle mittel - Google Patents

3-phenyl-furan-(5h)-2-on- und dihydrofuran-2-on-derivate als antibakterielle mittel

Info

Publication number
DE69717630T2
DE69717630T2 DE69717630T DE69717630T DE69717630T2 DE 69717630 T2 DE69717630 T2 DE 69717630T2 DE 69717630 T DE69717630 T DE 69717630T DE 69717630 T DE69717630 T DE 69717630T DE 69717630 T2 DE69717630 T2 DE 69717630T2
Authority
DE
Germany
Prior art keywords
dihydrofuran
furan
phenyl
derivatives
antibacterial agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69717630T
Other languages
English (en)
Other versions
DE69717630D1 (de
Inventor
Barry Gravestock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of DE69717630D1 publication Critical patent/DE69717630D1/de
Application granted granted Critical
Publication of DE69717630T2 publication Critical patent/DE69717630T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
DE69717630T 1996-05-11 1997-04-17 3-phenyl-furan-(5h)-2-on- und dihydrofuran-2-on-derivate als antibakterielle mittel Expired - Fee Related DE69717630T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9609919.7A GB9609919D0 (en) 1996-05-11 1996-05-11 Chemical compounds
PCT/GB1997/001061 WO1997043280A1 (en) 1996-05-11 1997-04-17 3-phenyl-furan-(5h)-2-one and dihydrofuran-2-one derivatives as antibacterial agents

Publications (2)

Publication Number Publication Date
DE69717630D1 DE69717630D1 (de) 2003-01-16
DE69717630T2 true DE69717630T2 (de) 2003-06-26

Family

ID=10793591

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69717630T Expired - Fee Related DE69717630T2 (de) 1996-05-11 1997-04-17 3-phenyl-furan-(5h)-2-on- und dihydrofuran-2-on-derivate als antibakterielle mittel

Country Status (7)

Country Link
US (3) US6110936A (de)
EP (1) EP0912561B1 (de)
JP (1) JP2000510143A (de)
AU (1) AU2572297A (de)
DE (1) DE69717630T2 (de)
GB (1) GB9609919D0 (de)
WO (1) WO1997043280A1 (de)

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GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
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US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
SI1427711T1 (sl) 2001-09-11 2005-12-31 Astrazeneca Ab Oksazolidinonski in/ali izoksazolinski derivati kot antibakterijska sredstva
EP1443930A1 (de) 2001-10-25 2004-08-11 AstraZeneca AB Isoxazolinderivative verwendbar als antimikrobielle agenzien
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
BR0308018A (pt) 2002-02-28 2005-01-04 Astrazeneca Ab Composto ou um seu sal farmaceuticamente aceitável ou um seu éster hidrolisável in vivo, pró-droga, método para produzir um efeito antibacteriano em um animal de sangue quente, uso de um composto ou um seu sal farmaceuticamente aceitável ou um seu éster hirolisável in vivo, composição farmacêutica, e, processo para a preparação de um composto ou um seu sal farmaceuticamente aceitável ou um seu éster hidrolisável in vivo
PL372191A1 (en) 2002-02-28 2005-07-11 Astrazeneca Ab 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents
EP1539745B1 (de) * 2002-08-12 2006-03-29 Pharmacia & Upjohn Company LLC N-aryl-2-oxazolidinone und deren derivate
AU2003280143A1 (en) * 2002-11-21 2004-06-15 Pharmacia & Upjohn Company Llc N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinone-5-carboxamide derivates and related compounds as antibacterial agents
BRPI0407304A (pt) * 2003-02-07 2006-01-10 Warner Lambert Co Agentes antibacterianos
BRPI0407252A (pt) * 2003-02-07 2006-01-31 Warner Lambert Co Agentes antibacterianos.
US20040204463A1 (en) * 2003-04-01 2004-10-14 Harris Christina Renee N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
WO2004106329A2 (en) * 2003-06-03 2004-12-09 Dr. Reddy's Laboratories Ltd. Novel antiinfective compounds and their pharmaceutical compositions
US7687627B2 (en) * 2003-09-08 2010-03-30 Wockhardt Limited Substituted piperidino phenyloxazolidinones having antimicrobial activity with improved in vivo efficacy
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
JP2008509125A (ja) * 2004-08-06 2008-03-27 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 抗菌剤としてのオキシンドールオキサゾリジノン
GB0500895D0 (en) * 2005-01-17 2005-02-23 Isis Innovation Biocidal surface functionalisation
GB0616724D0 (en) * 2006-08-23 2006-10-04 Isis Innovation Surface adhesion using arylcarbene reactive intermediates
US9193678B2 (en) 2009-03-02 2015-11-24 Oxford Advanced Surfaces Ltd Chemical agents capable of forming covalent 3-D networks

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FR2458547B2 (fr) * 1978-06-09 1986-05-16 Delalande Sa Nouvelles n-aryle azolones, leur procede de preparation et leur application en therapeutique
CH647772A5 (fr) * 1979-05-07 1985-02-15 Delalande Sa Derives de la 5h-furanone-2 et de la 3h-dihydro-furanone-2, leurs procedes de preparation, et medicament les contenant.
FR2456097A1 (fr) * 1979-05-07 1980-12-05 Delalande Sa Nouveaux derives de la 5 h-furanone-2 et de la 3 h-dihydrofuranone-2, leur procede de preparation et leur application en therapeutique
FR2500450A1 (fr) * 1981-02-25 1982-08-27 Delalande Sa Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
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CA1260948A (en) * 1984-12-05 1989-09-26 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents
CA1320730C (en) * 1987-10-16 1993-07-27 The Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
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JPH0873455A (ja) * 1994-03-15 1996-03-19 Upjohn Co:The オキサゾリジノン誘導体及びこれを有効成分とする医薬組成物
DE4425609A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl- und Benzothienyloxazolidinone
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
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DE19514313A1 (de) * 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone
JP3933198B2 (ja) * 1994-10-26 2007-06-20 ファルマシア・アンド・アップジョン・カンパニー フェニルオキサゾリジノン抗菌剤
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Also Published As

Publication number Publication date
GB9609919D0 (en) 1996-07-17
DE69717630D1 (de) 2003-01-16
US6350775B1 (en) 2002-02-26
US20030166684A1 (en) 2003-09-04
AU2572297A (en) 1997-12-05
WO1997043280A1 (en) 1997-11-20
US6110936A (en) 2000-08-29
EP0912561B1 (de) 2002-12-04
EP0912561A1 (de) 1999-05-06
JP2000510143A (ja) 2000-08-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee