DE69716925D1 - Isoxazoline derivate und ihre verwendung als antimikroben - Google Patents

Isoxazoline derivate und ihre verwendung als antimikroben

Info

Publication number
DE69716925D1
DE69716925D1 DE69716925T DE69716925T DE69716925D1 DE 69716925 D1 DE69716925 D1 DE 69716925D1 DE 69716925 T DE69716925 T DE 69716925T DE 69716925 T DE69716925 T DE 69716925T DE 69716925 D1 DE69716925 D1 DE 69716925D1
Authority
DE
Germany
Prior art keywords
antimicrobe
isoxazoline derivatives
isoxazoline
derivatives
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69716925T
Other languages
English (en)
Other versions
DE69716925T2 (de
Inventor
R Barbachyn
C Thomas
J Cleek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Publication of DE69716925D1 publication Critical patent/DE69716925D1/de
Application granted granted Critical
Publication of DE69716925T2 publication Critical patent/DE69716925T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
DE69716925T 1996-08-21 1997-08-15 Isoxazoline derivate und ihre verwendung als antimikroben Expired - Fee Related DE69716925T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2428796P 1996-08-21 1996-08-21
PCT/US1997/013934 WO1998007708A1 (en) 1996-08-21 1997-08-15 Isoxazoline derivatives useful as antimicrobials

Publications (2)

Publication Number Publication Date
DE69716925D1 true DE69716925D1 (de) 2002-12-12
DE69716925T2 DE69716925T2 (de) 2003-09-11

Family

ID=21819822

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69716925T Expired - Fee Related DE69716925T2 (de) 1996-08-21 1997-08-15 Isoxazoline derivate und ihre verwendung als antimikroben

Country Status (10)

Country Link
US (2) US5990136A (de)
EP (1) EP0920421B1 (de)
JP (1) JP2000516245A (de)
AT (1) ATE227277T1 (de)
AU (1) AU3973697A (de)
DE (1) DE69716925T2 (de)
DK (1) DK0920421T3 (de)
ES (1) ES2186916T3 (de)
PT (1) PT920421E (de)
WO (1) WO1998007708A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
WO1998054161A1 (en) 1997-05-30 1998-12-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
NZ506292A (en) * 1998-02-13 2003-05-30 Upjohn Co Substituted aminophenyl isoxazoline methylamide derivatives useful as antimicrobials
EP1060179A1 (de) * 1998-02-25 2000-12-20 PHARMACIA & UPJOHN COMPANY Substituierte aminomethyl isoxazolin derivate verwendbar als antimikrobielle mittel
EE200000707A (et) 1998-06-05 2002-04-15 Astrazeneca Ab Oksasolidinooni derivaadid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid
TW572757B (en) * 1998-08-24 2004-01-21 Bristol Myers Squibb Co Novel isoxazolinone antibacterial agents
US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
ES2256331T3 (es) 2000-12-21 2006-07-16 PHARMACIA & UPJOHN COMPANY LLC Derivados de quinolina antimicrobianos y uso de los mismos para tratar infecciones bacterianas.
JPWO2002053523A1 (ja) * 2000-12-26 2004-04-30 財団法人乙卯研究所 トロポロン誘導体
EP1443930A1 (de) * 2001-10-25 2004-08-11 AstraZeneca AB Isoxazolinderivative verwendbar als antimikrobielle agenzien
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
BRPI0407304A (pt) * 2003-02-07 2006-01-10 Warner Lambert Co Agentes antibacterianos
BRPI0407252A (pt) * 2003-02-07 2006-01-31 Warner Lambert Co Agentes antibacterianos.
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
WO2005082900A2 (en) * 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone amidoximes as antibacterial agents
JP2008509125A (ja) * 2004-08-06 2008-03-27 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 抗菌剤としてのオキシンドールオキサゾリジノン
KR101508862B1 (ko) * 2010-08-05 2015-04-07 조에티스 엘엘씨 구충제로서 이속사졸린 유도체
US9173887B2 (en) 2010-12-22 2015-11-03 Abbvie Inc. Hepatitis C inhibitors and uses thereof
US9938816B2 (en) * 2012-10-03 2018-04-10 Shell Oil Company Optimizing performance of a drilling assembly
WO2021000297A1 (en) * 2019-07-03 2021-01-07 Merck Sharp & Dohme Corp. Compounds and methods of use thereof as antibacterial agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL137326C (de) * 1967-08-26
US4283403A (en) * 1976-06-14 1981-08-11 Eli Lilly And Company Substituted isoxazolines for control of plant phytopathogens
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
CA2147753C (en) * 1992-12-08 2004-08-03 Michael Robert Barbachyn Tropone-substituted phenyloxazolidinone antibacterial agents
ATE187447T1 (de) * 1993-11-26 1999-12-15 Pfizer 3-phenyl-2-isoxazoline derivate als entzündugshemmende mittel
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
US5710159A (en) * 1996-05-09 1998-01-20 The Dupont Merck Pharmaceutical Company Integrin receptor antagonists

Also Published As

Publication number Publication date
DK0920421T3 (da) 2003-03-10
EP0920421A1 (de) 1999-06-09
PT920421E (pt) 2003-03-31
DE69716925T2 (de) 2003-09-11
EP0920421B1 (de) 2002-11-06
ES2186916T3 (es) 2003-05-16
AU3973697A (en) 1998-03-06
US6093736A (en) 2000-07-25
ATE227277T1 (de) 2002-11-15
JP2000516245A (ja) 2000-12-05
US5990136A (en) 1999-11-23
WO1998007708A1 (en) 1998-02-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee