DE60035127D1 - POLYSACCHARIDE-COATED CARRIER, THEIR MANUFACTURE AND USE - Google Patents

POLYSACCHARIDE-COATED CARRIER, THEIR MANUFACTURE AND USE

Info

Publication number
DE60035127D1
DE60035127D1 DE60035127T DE60035127T DE60035127D1 DE 60035127 D1 DE60035127 D1 DE 60035127D1 DE 60035127 T DE60035127 T DE 60035127T DE 60035127 T DE60035127 T DE 60035127T DE 60035127 D1 DE60035127 D1 DE 60035127D1
Authority
DE
Germany
Prior art keywords
polysaccharide
manufacture
coated carrier
coated
carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60035127T
Other languages
German (de)
Other versions
DE60035127T2 (en
Inventor
Hrair Kirakossian
John S Pease
Carsten Schelp
Marcel R Pirio
Uwe Stohr
Andreas Wiegand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Products GmbH
Original Assignee
Dade Behring Marburg GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade Behring Marburg GmbH filed Critical Dade Behring Marburg GmbH
Application granted granted Critical
Publication of DE60035127D1 publication Critical patent/DE60035127D1/en
Publication of DE60035127T2 publication Critical patent/DE60035127T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/548—Carbohydrates, e.g. dextran
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/969—Multiple layering of reactants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/827—Lectins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
DE60035127T 2000-03-06 2000-03-06 POLYSACCHARIDE-COATED CARRIER, THEIR MANUFACTURE AND USE Expired - Lifetime DE60035127T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/005978 WO2001067105A1 (en) 2000-03-06 2000-03-06 Carriers coated with polysaccharides, their preparation and use

Publications (2)

Publication Number Publication Date
DE60035127D1 true DE60035127D1 (en) 2007-07-19
DE60035127T2 DE60035127T2 (en) 2008-02-14

Family

ID=21741129

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60035127T Expired - Lifetime DE60035127T2 (en) 2000-03-06 2000-03-06 POLYSACCHARIDE-COATED CARRIER, THEIR MANUFACTURE AND USE

Country Status (7)

Country Link
US (1) US7179660B1 (en)
EP (1) EP1264181B1 (en)
JP (1) JP4448642B2 (en)
CA (1) CA2400993C (en)
DE (1) DE60035127T2 (en)
ES (1) ES2287006T3 (en)
WO (1) WO2001067105A1 (en)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020164825A1 (en) * 2000-09-09 2002-11-07 Wen-Tien Chen Cell separation matrix
EP1546723A4 (en) * 2002-08-16 2007-03-07 Decision Biomarkers Inc Reading of fluorescent arrays
DE10318801A1 (en) * 2003-04-17 2004-11-04 Aesculap Ag & Co. Kg Flat implant and its use in surgery
EP1494028A1 (en) * 2003-07-03 2005-01-05 Labsoft Diagnostics AG Immunomagnetic separation of specific target cells
JP4665161B2 (en) * 2004-02-06 2011-04-06 国立大学法人高知大学 Method for measuring Raman spectrum, noble metal particles used in the method, and method for producing the noble metal particles
CN104090097B (en) * 2004-02-26 2017-04-12 康多尔生物技术有限公司 Aqueous solution of specificity binding interaction culture medium serving as binding pair
US7887880B2 (en) * 2004-06-30 2011-02-15 Auburn University Preparation and application of stabilized iron nanoparticles for dechlorination of chlorinated hydrocarbons in soils, sediments, and ground water
US20060040258A1 (en) * 2004-08-23 2006-02-23 Huiyan Guo Water-soluble conjugates and methods of preparation
DE102004042124B4 (en) * 2004-08-30 2006-07-06 Dade Behring Marburg Gmbh Homogeneous method for the determination of an analyte in the presence of an excess of cross-reacting substances
CA2595292C (en) * 2005-01-20 2014-03-04 Luminex Corporation Magnetic microspheres for use in fluorescence-based applications
US20060166376A1 (en) * 2005-01-21 2006-07-27 Craig Alan R Compositions for use as a signal generation component and methods of using same
EP1715344A1 (en) * 2005-04-22 2006-10-25 Universiteit Utrecht Holding B.V. Immobilisation of antigenic carbohydrates to support detection of pathogenic micro-organisms
JP2006321932A (en) * 2005-05-20 2006-11-30 Jsr Corp Carrier polymer particle and its production method
JP4873123B2 (en) * 2005-11-28 2012-02-08 Ｊｓｒ株式会社 Method for producing carrier polymer particles
WO2006123686A1 (en) * 2005-05-20 2006-11-23 Jsr Corporation Support polymer particle, process for producing the same, magnetic particle for specific trapping, and process for producing the same
JP5007920B2 (en) * 2005-08-31 2012-08-22 日立金属株式会社 Nucleic acid extraction method, cancer cell detection method and magnetic beads
SG131016A1 (en) 2005-09-19 2007-04-26 Millipore Corp Asymmetric porous adsorptive bead
MX2008007716A (en) 2005-12-13 2008-09-26 Exthera Ab Method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from blood.
EP2015071A1 (en) * 2007-07-13 2009-01-14 FUJIFILM Corporation Carrier, process for producing same, bioreactor, and chip for surface plasmon resonance analysis
WO2009064977A2 (en) * 2007-11-14 2009-05-22 E.I. Du Pont De Nemours And Company Dextran-based polymer tissue adhesive for medical use
CA2723076A1 (en) * 2008-05-09 2009-11-12 Zhiping Liu A molecule detecting system
JP5253974B2 (en) * 2008-11-14 2013-07-31 株式会社コーセー MULTILAYER COATED PARTICLE, PROCESS FOR PRODUCING THE SAME, AND EXTERNAL SKIN CONTAINING THE SAME
US20120149128A1 (en) * 2009-02-23 2012-06-14 Victor Manneh Assays and assay devices
EP2230515B1 (en) 2009-03-16 2014-12-17 Agilent Technologies, Inc. Passivation of surfaces after ligand coupling
US20120225496A1 (en) 2009-11-17 2012-09-06 Satoru Yoshida Organic colored microparticles, diagnostic reagent kit containing the same, and in vitro diagnosis method
CN106178161B (en) 2009-12-01 2020-12-22 艾克塞拉医疗公司 Method for removing cytokines from blood using surface immobilized polysaccharides
CN102109521A (en) * 2010-12-16 2011-06-29 中国环境科学研究院 Immunolatex microsphere for detecting CpTI and preparation method thereof
WO2012112724A1 (en) 2011-02-15 2012-08-23 Exthera Medical, Llc Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines
US8394647B2 (en) 2011-02-17 2013-03-12 Siemens Healthcare Diagnostics Inc. Reducing non-covalently bound polysaccharide on supports
EP2541250A1 (en) * 2011-06-30 2013-01-02 Koninklijke Philips Electronics N.V. Molecular architecture on magnetic particles for affinity assays with low non-specific binding
WO2013070653A1 (en) * 2011-11-09 2013-05-16 Board Of Trustees Michigan State University Metallic nanoparticle synthesis with carbohydrate capping agent
JP6226958B2 (en) * 2012-04-18 2017-11-08 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドＳｉｅｍｅｎｓ Ｈｅａｌｔｈｃａｒｅ Ｄｉａｇｎｏｓｔｉｃｓ Ｉｎｃ． COMPOUNDS AND METHODS FOR PRODUCING CONJUGATE REAGENTS
EP2861273B1 (en) 2012-06-13 2017-08-23 ExThera Medical Corporation Use of heparin and carbohydrates to treat cancer
US9244083B2 (en) 2012-11-30 2016-01-26 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting vitamin D
US20140308751A1 (en) 2013-04-12 2014-10-16 Siemens Healthcare Diagnostics Inc. Assays for Analyte Homologs
EP3013445B1 (en) * 2013-06-24 2019-11-06 ExThera Medical Corporation Blood filtration system containing mannose coated substrate
US10124072B2 (en) * 2013-09-18 2018-11-13 Caliper Life Sciences, Inc. In-vivo reactive species imaging
WO2015069942A1 (en) 2013-11-08 2015-05-14 Exthera Medical Corporation Methods for diagnosing infectious diseases using adsorption media
BR112016024569B1 (en) 2014-04-24 2023-01-03 Exthera Medical Corporation EX VIVO METHOD FOR REMOVING BACTERIA FROM A SPECIMEN TAKEN FROM AN INDIVIDUAL WHO IS SUSPECTED TO BE INFECTED WITH THE SAME
JP6681349B2 (en) 2014-06-27 2020-04-15 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドＳｉｅｍｅｎｓ Ｈｅａｌｔｈｃａｒｅ Ｄｉａｇｎｏｓｔｉｃｓ Ｉｎｃ． Binding partners specific for vitamin D epimers
KR20170016009A (en) 2014-06-27 2017-02-10 지멘스 헬쓰케어 다이아그노스틱스 인크. Binding partners specific for vitamin d epimers in vitamin d assays
EP3197342B1 (en) 2014-09-22 2020-08-05 ExThera Medical Corporation Wearable hemoperfusion device
JP6852259B2 (en) * 2016-01-07 2021-03-31 昭和電工マテリアルズ株式会社 Separator and column
US11911551B2 (en) 2016-03-02 2024-02-27 Exthera Medical Corporation Method for treating drug intoxication
EP3422943A4 (en) 2016-03-02 2019-10-16 ExThera Medical Corporation Method for treating drug intoxication
CN116337851A (en) * 2018-07-18 2023-06-27 科美博阳诊断技术(上海)有限公司 Homogeneous chemiluminescence detection kit and application thereof
CN116559151A (en) * 2018-07-18 2023-08-08 上海索昕生物科技有限公司 Microsphere composition for chemiluminescence detection and application thereof
CN110736737A (en) * 2018-07-18 2020-01-31 博阳生物科技（上海）有限公司 microsphere composition for chemiluminescence detection and application thereof
US20210247398A1 (en) 2018-07-30 2021-08-12 Siemens Healthcare Diagnostics Inc. Kits, microfluidics devices, and methods for performing biotin assays
WO2020068541A1 (en) 2018-09-25 2020-04-02 Siemens Healthcare Diagnostics Inc. Methods and compositions for removing biotin interference from assays using molecular traps
CN116626285A (en) * 2019-07-19 2023-08-22 科美博阳诊断技术(上海)有限公司 Homogeneous chemiluminescence analysis method and application thereof
CN116577512A (en) * 2019-07-19 2023-08-11 科美博阳诊断技术(上海)有限公司 Application of donor reagent in diagnosis of myocardial injury of subject
CN116754757A (en) * 2019-07-19 2023-09-15 上海索昕生物科技有限公司 Donor particle for homogeneous chemiluminescence analysis and application thereof
CN112240928B (en) * 2019-07-19 2023-06-13 科美博阳诊断技术(上海)有限公司 Homogeneous chemiluminescence analysis method and application thereof
CN112240937B (en) * 2019-07-19 2023-06-13 科美博阳诊断技术(上海)有限公司 Application of donor reagent in diagnosis of bacterial inflammatory diseases of subject infection
CN110441531B (en) * 2019-08-17 2022-08-23 宁波奥丞生物科技有限公司 Kit for detecting procalcitonin in blood and preparation method thereof
CN110895283A (en) * 2019-12-10 2020-03-20 宁波奥丞生物科技有限公司 High-sensitivity D-dimer detection kit and use method thereof
CN110907654A (en) * 2019-12-10 2020-03-24 宁波奥丞生物科技有限公司 Free estriol quantitative detection kit and preparation method thereof
CN113125730B (en) * 2019-12-31 2023-07-07 科美博阳诊断技术(上海)有限公司 Homogeneous detection kit for interleukin 6 and application thereof
CN113125711B (en) * 2019-12-31 2023-07-28 科美博阳诊断技术(上海)有限公司 Acceptor reagent and application thereof
CN113125732B (en) * 2019-12-31 2023-08-08 科美博阳诊断技术(上海)有限公司 Homogeneous detection kit for interleukin 6 and application thereof
CN113125721B (en) * 2019-12-31 2023-07-07 科美博阳诊断技术(上海)有限公司 Homogeneous detection kit for creatine kinase isozymes and application thereof
CN116859057A (en) * 2019-12-31 2023-10-10 科美诊断技术(苏州)有限公司 Myoglobin homogeneous detection kit and application thereof
CN113125714B (en) * 2019-12-31 2023-06-16 科美博阳诊断技术(上海)有限公司 Human immunodeficiency virus antibody detection kit and application thereof
CN113125701B (en) * 2019-12-31 2024-01-30 科美博阳诊断技术(上海)有限公司 Homogeneous chemiluminescence detection kit and application thereof
CN116400074A (en) * 2019-12-31 2023-07-07 科美博阳诊断技术(上海)有限公司 CRP detection kit and application thereof
CN117805359A (en) * 2019-12-31 2024-04-02 科美诊断技术(苏州)有限公司 Myoglobin homogeneous detection kit and application thereof
CN113125700B (en) * 2019-12-31 2023-08-08 科美博阳诊断技术(上海)有限公司 Homogeneous detection kit for creatine kinase isozymes and application thereof
GB2616351A (en) * 2021-12-01 2023-09-06 Droplet Genomics Uab Core-shell microcapsules, manufacturing processes and uses

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
CA1190838A (en) 1981-07-17 1985-07-23 Cavit Akin Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer
EP0136347A1 (en) 1983-02-25 1985-04-10 Covalent Technology Corporation Insoluble surfaces treated to inhibit non-specific protein binding
US4891324A (en) 1987-01-07 1990-01-02 Syntex (U.S.A.) Inc. Particle with luminescer for assays
EP0438534A4 (en) 1988-10-11 1991-09-11 Coulter Corporation Immunoreactant carriers having a novel biocompatible intermediate coating and process of making same
US5466609A (en) * 1990-10-31 1995-11-14 Coulter Corporation Biodegradable gelatin-aminodextran particle coatings of and processes for making same
US5169754A (en) * 1990-10-31 1992-12-08 Coulter Corporation Biodegradable particle coatings having a protein covalently immobilized by means of a crosslinking agent and processes for making same
US5639620A (en) * 1990-10-31 1997-06-17 Coulter Corporation Polymeric particles having a biodegradable gelatin or aminodextran coating and process for making same
AU652804B2 (en) 1991-01-19 1994-09-08 Meito Sangyo Kabushiki Kaisha Composition containing ultrafine particles of magnetic metal oxide
FR2672128B1 (en) 1991-01-28 1995-08-18 Cis Bio Int METHOD FOR MEASURING THE LUMINESCENCE EMITTED IN A LUMINESCENCE ASSAY.
US5578498A (en) 1991-05-22 1996-11-26 Behringwerke Ag Metal chelate containing compositions for use in chemiluminescent assays
IL101945A (en) 1991-05-22 1998-02-08 Behringwerke Ag Methods for determining an analyte using induced luminescence, and kits therefor
DE4117782C2 (en) * 1991-05-28 1997-07-17 Diagnostikforschung Inst Nanocrystalline magnetic iron oxide particles, processes for their production and diagnostic and / or therapeutic agents
WO1994002486A1 (en) 1992-07-20 1994-02-03 Syntex (U.S.A.) Inc. Novel chemiluminescent compounds and methods of use
WO1994003501A1 (en) * 1992-08-05 1994-02-17 Meito Sangyo Kabushiki Kaisha Small-diameter composite composed of water-soluble carboxypolysaccharide and magnetic iron oxide
DE69331970T2 (en) 1992-10-15 2002-12-19 Coulter Int Corp PARTICLES WITH GELATINE-AMINODEXTRAN COVERS AND METHOD FOR THE PRODUCTION THEREOF
EP0716746B1 (en) 1993-09-03 1999-03-17 Behringwerke Ag Fluorescent oxygen channeling immunoassays
DE4428851C2 (en) 1994-08-04 2000-05-04 Diagnostikforschung Inst Nanoparticles containing iron, their production and application in diagnostics and therapy
DE19509694A1 (en) 1995-03-08 1996-09-19 Schering Ag Use of magnetites to determine the perfusion of human tissue using MR diagnostics
US5786161A (en) 1996-06-06 1998-07-28 Miltenyi Biotec. Gmbh Isolation and characterization of allergen-binding cells for diagnosis of hypersensitivity
US6231982B1 (en) 1997-12-10 2001-05-15 Dade Behring Inc. Particle reagents having reduced matrix effects and containing an aldehyde-reactive functional group

Also Published As

Publication number Publication date
JP2003526786A (en) 2003-09-09
DE60035127T2 (en) 2008-02-14
ES2287006T3 (en) 2007-12-16
EP1264181A1 (en) 2002-12-11
CA2400993C (en) 2011-06-07
JP4448642B2 (en) 2010-04-14
EP1264181B1 (en) 2007-06-06
US7179660B1 (en) 2007-02-20
WO2001067105A1 (en) 2001-09-13
CA2400993A1 (en) 2001-09-13

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Owner name: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH, , DE