DE3568333D1 - Novel 4,5-bis(4-methoxyphenyl)-2-(pyrrol-2-yl)thiazoles, process for the preparation thereof and pharmaceutical composition containing the same - Google Patents
Novel 4,5-bis(4-methoxyphenyl)-2-(pyrrol-2-yl)thiazoles, process for the preparation thereof and pharmaceutical composition containing the sameInfo
- Publication number
- DE3568333D1 DE3568333D1 DE8585104786T DE3568333T DE3568333D1 DE 3568333 D1 DE3568333 D1 DE 3568333D1 DE 8585104786 T DE8585104786 T DE 8585104786T DE 3568333 T DE3568333 T DE 3568333T DE 3568333 D1 DE3568333 D1 DE 3568333D1
- Authority
- DE
- Germany
- Prior art keywords
- thiazoles
- pyrrol
- methoxyphenyl
- bis
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7992484A JPS60222481A (ja) | 1984-04-19 | 1984-04-19 | 新規なジフエニルピロリルチアゾ−ル誘導体、その製造法およびそれを有効成分とする医薬組成物 |
| JP15618484A JPS6133186A (ja) | 1984-07-25 | 1984-07-25 | 新規なジフエニルピロリルチアゾ−ル誘導体、その製造法およびそれを有効成分とする医薬組成物 |
| JP4080285A JPS61200985A (ja) | 1985-02-28 | 1985-02-28 | 新規なジフエニルピロリルチアゾ−ル誘導体、その製造法およびそれを有効成分とする医薬組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3568333D1 true DE3568333D1 (en) | 1989-03-30 |
Family
ID=27290610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8585104786T Expired DE3568333D1 (en) | 1984-04-19 | 1985-04-19 | Novel 4,5-bis(4-methoxyphenyl)-2-(pyrrol-2-yl)thiazoles, process for the preparation thereof and pharmaceutical composition containing the same |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US4659726A (de) |
| EP (1) | EP0159677B1 (de) |
| DE (1) | DE3568333D1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2036192A1 (en) | 1990-02-13 | 1991-08-14 | Nicholas Meanwell | Heterocyclic carboxylic acids and esters |
| US5077305A (en) * | 1990-02-13 | 1991-12-31 | Bristol-Myers Squibb Co. | Thiazole carboxylic acids and esters |
| CA2396738C (en) | 1990-11-30 | 2006-08-29 | Masatoshi Chihiro | Thiazole derivatives as active superoxide radical inhibitors |
| IT1254199B (it) * | 1992-02-06 | 1995-09-14 | Ministero Dell Uni E Della | Tiazolilpirroli ad attivita' fungicida |
| GB9617611D0 (en) * | 1996-08-22 | 1996-10-02 | Vasogen Inc | Treatment of autoimmune disease |
| US6669965B2 (en) | 1992-02-07 | 2003-12-30 | Vasogen Ireland Limited | Method of treating atherosclerosis |
| US5591457A (en) * | 1992-02-07 | 1997-01-07 | Vasogen Inc | Method of inhibiting the aggregation of blood platelets and stimulating the immune systems of a human |
| US5980954A (en) | 1992-02-07 | 1999-11-09 | Vasogen Ireland Limited | Treatment of autoimmune diseases |
| US6204058B1 (en) | 1992-02-07 | 2001-03-20 | Vasogen Ireland Limited | Treatment of autoimmune diseases |
| JPH05229943A (ja) * | 1992-02-25 | 1993-09-07 | Kanebo Ltd | 脳保護剤 |
| MY128323A (en) | 1996-09-30 | 2007-01-31 | Otsuka Pharma Co Ltd | Thiazole derivatives for inhibition of cytokine production and of cell adhesion |
| JP2010501567A (ja) | 2006-08-24 | 2010-01-21 | ノバルティス アクチエンゲゼルシャフト | 代謝系、心血管系および他の障害の処置のためのステアロイル−ＣｏＡ不飽和化酵素（ＳＣＤ）阻害剤としての２−（ピラジン−２−イル）−チアゾールおよび２−（１Ｈ−ピラゾール−３−イル）チアゾール誘導体ならびに関連化合物 |
| CN101516877B (zh) | 2006-09-22 | 2013-09-11 | 诺瓦提斯公司 | 杂环有机化合物 |
| CA2672776A1 (en) | 2006-12-20 | 2008-06-26 | Novartis Ag | 2-substituted 5-membered heterocycles as scd inhibitors |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4168315A (en) * | 1977-09-28 | 1979-09-18 | The Upjohn Company | Dianisyl thiazole compound, compositions and method of antithrombotic treatment |
| US4322428A (en) * | 1980-04-02 | 1982-03-30 | Eli Lilly And Company | 2(4-Fluorophenyl)-4,5,-bis(4-methoxyphenyl)thiazole and method of use |
| DE3141063A1 (de) * | 1981-10-13 | 1983-04-28 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue imidazol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
-
1985
- 1985-04-12 US US06/722,322 patent/US4659726A/en not_active Expired - Lifetime
- 1985-04-19 EP EP85104786A patent/EP0159677B1/de not_active Expired
- 1985-04-19 DE DE8585104786T patent/DE3568333D1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0159677A2 (de) | 1985-10-30 |
| EP0159677A3 (en) | 1987-01-28 |
| EP0159677B1 (de) | 1989-02-22 |
| US4659726A (en) | 1987-04-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |