CN1295486A - Metered dose infusion pump and method - Google Patents
Metered dose infusion pump and method Download PDFInfo
- Publication number
- CN1295486A CN1295486A CN99804498A CN99804498A CN1295486A CN 1295486 A CN1295486 A CN 1295486A CN 99804498 A CN99804498 A CN 99804498A CN 99804498 A CN99804498 A CN 99804498A CN 1295486 A CN1295486 A CN 1295486A
- Authority
- CN
- China
- Prior art keywords
- pump
- liquid
- pump head
- outlet
- head
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract description 15
- 238000001802 infusion Methods 0.000 title abstract description 5
- 239000007788 liquid Substances 0.000 claims abstract description 97
- 230000009021 linear effect Effects 0.000 claims abstract description 36
- 210000004204 blood vessel Anatomy 0.000 claims abstract description 5
- 239000012530 fluid Substances 0.000 claims description 42
- 210000003128 head Anatomy 0.000 claims description 39
- 230000007246 mechanism Effects 0.000 claims description 17
- 210000003928 nasal cavity Anatomy 0.000 claims description 8
- 239000003814 drug Substances 0.000 claims description 5
- 238000002347 injection Methods 0.000 claims description 5
- 239000007924 injection Substances 0.000 claims description 5
- 239000006199 nebulizer Substances 0.000 claims description 5
- 230000009471 action Effects 0.000 claims description 3
- 238000001514 detection method Methods 0.000 claims 1
- 230000008878 coupling Effects 0.000 abstract description 4
- 238000010168 coupling process Methods 0.000 abstract description 4
- 238000005859 coupling reaction Methods 0.000 abstract description 4
- 238000004891 communication Methods 0.000 abstract 1
- 238000005086 pumping Methods 0.000 description 7
- 238000010253 intravenous injection Methods 0.000 description 5
- 238000007599 discharging Methods 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 239000004973 liquid crystal related substance Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000009849 deactivation Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
Abstract
An intravascular administration set (14) includes an axially actuated reciprocating pump head (98) having a pump head inlet (110) and a pump head outlet (112). An inlet tube (96) has a first end attached to the pump head inlet (110) and a second end adapted for coupling with a liquid reservoir. An outlet tube (100) has a first end coupled to the pump head outlet (112) and a second end adapted for coupling in liquid communication with a blood vessel of a patient. The pump head inlet (110) and the pump head outlet (118) of the axially reciprocating pump head (98) are disposed axially of the pump head (98). An intravascular infusion pump (80) incorporates the administration set (14) and includes a linear reciprocating drive operatively associated with the pump head (98). The liquid reservoir may be a syringe (94) and liquid is pumped from the syringe by creating a negative pressure at the syringe outlet (108). A method of intravascular infusion of liquid utilizes the administration set (14) and linear reciprocating drive (132).
Description
Technical field
The present invention relates to topping-up pump, relate more specifically to a kind of metered dose infusion pump, a kind of administration assembly that is used for topping-up pump and a kind of method of carrying the ormal weight medicinal liquid when being used for that the patient carried out intravascular injection.
Background technology
In the last few years, extensively adopted the topping-up pump pressure device of carrying medicinal liquid in the patient managed in hospital or other patient care place.Because transporting velocity mediating recipe measurer has higher accuracy and can change the administration delivery profile to optimize drug effect, therefore, topping-up pump has replaced the injecting systems of GRAVITY CONTROL under many occasions.Topping-up pump be specially adapted to whole long-time during, with the consumption of accurate mensuration and timing the patient is supplied with dangerous drug, so that drug effect and patient's safety reaches maximization.
In order to ensure accurate consumption, there has been the trend of the more accurate complicated pumping equipment of manufacturing with potential danger medicine.Though, can successfully improve the pumping precision technically at present, still there are some serious defectives.The more important thing is that many these pumps all depend on very accurate and complicated driving arrangement and pump head structure, therefore increased the complexity and the cost of pump.For example, design more accurate peristaltic pump though spent very big effort, this pump relies on a low-cost IV pipe as disposable pump chamber,, try hard to increase the raising that accuracy will inevitably cause the complicated and cost of pump configuration greatly.Utilize disposable box body also can run into requirement reduction manufacturing cost, improve the problem of reliability and the accurate box body of employing as the Producer of the pump of pump head.
The objective of the invention is to overcome above-mentioned one or more problem.
Summary of the invention
First aspect of the present invention provides administration assembly in a kind of pipe, and it comprises: the reciprocating pump pressure head of an axially-movable, this pump head have pump head inlet and pump head outlet.One input pipe has first end that is installed in the pump head inlet and reaches and second end that is suitable for linking to each other with a liquid reservoir.One outlet tube has first end and that links to each other with the pump head outlet and is suitable for liquid second end that links to each other with a patient vessel.The pump head of reciprocating pump pressure head enters the mouth and the pump head outlet is best axially is provided with along pump head.Administration assembly can comprise a liquid reservoir that links to each other with input pipe second end, and liquid reservoir comprises a syringe simultaneously.In a most preferred embodiment, the reciprocating pump pressure head of axially-movable comprises that one slidably is contained in the piston in the fluid cylinder, described piston in fluid cylinder exhaust position and recharge between the position and to move so that liquid stream suction pump head inlet, and discharge from the pump head outlet.One control valve and fluid cylinder are liquid to link to each other, to move to when recharging the position from exhaust position when piston, impels liquid stream only to enter fluid cylinder from the pump head inlet, and when piston when the position of recharging moves to exhaust position, impel liquid stream only to export discharge from pump head.One connecting rod is assemblied on the piston, is used at the exhaust position and the mobile piston between the position that recharges, and connecting rod engages with a linear reciprocating drive unit.
A second aspect of the present invention provides topping-up pump in a kind of pipe, and it comprises: the reciprocating pump pressure head of an axially-movable, this pump head have pump head inlet and pump head outlet.One housing comprises that one holds the pump head receptor of pump head.One liquid reservoir links to each other by an input pipe and pump intake are liquid.One outlet tube has with liquid first end that links to each other of pump head outlet and is suitable for liquid second end that links to each other with a patient vessel.One controllably links to each other with pump head at the intravital linear reciprocating drive unit of shell, with the driving pump pressure head.Liquid reservoir preferably also is arranged in the housing.In another kind of optimum structure, a controller controllably links to each other with the reciprocal linear driving device, is used for the preset program operation of control pump pressure head, and provides an ideal curve of output.In another most preferred embodiment, the reciprocating pump pressure head of axially-movable comprises that one slidably is contained in the piston in the fluid cylinder, described piston can be in fluid cylinder the exhaust position and the axially-movable between the position of recharging, with liquid suction pump pressure head inlet and from pump head outlet drain.When piston moves to when recharging the position from exhaust position, one makes liquid stream only enter fluid cylinder from the pump head inlet with the liquid control valve that links to each other of fluid cylinder, and when piston when the position of recharging moves to exhaust position, make liquid stream only export discharge from pump head.One is assembled to the connecting rod of piston at the exhaust position and the mobile piston between the position that recharges.Described connecting rod engages with a linear reciprocating drive unit.Linear reciprocating drive unit preferably includes the rotating mechanism of the converter,linear that a motor and with a rotating driveshaft controllably links to each other with the reciprocating pump pressure head of driving shaft and axially-movable, in order to the driving pump pressure head.The cam and one that the off-centre that can comprise the rotating mechanism of converter,linear is fixed on the motor drive shaft is subjected to bias voltage to contact the cam-follower of cam edge.When cam rotates, make linear reciprocal movement with the cam-follower that the reciprocating pump pressure head of axially-movable links to each other.One encoder that links to each other with motor and controller electric coupling are so that can accurately monitor the output of pump.
A third aspect of the present invention provide a kind of the patient is managed in the method for liquid medicine injection, this method comprises the reciprocating pump pressure head that an axially-movable is set, this pump head has pump head inlet and a pump head exports and be provided with input pipe and outlet tube.First end of input pipe links to each other with the pump head inlet is liquid, and second end of input pipe links to each other with a liquid reservoir is liquid.First end of outlet tube links to each other with the pump head outlet is liquid, and second end links to each other with patient's blood vessel is liquid.The reciprocal linear driving device controllably links to each other with pump head and is handled and makes liquid be disposed to the patient vessel from liquid reservoir, in a most preferred embodiment of this method, the reciprocating pump pressure head of axially-movable is the quantitative atomizing pump of the nasal cavity mechanism that comprises a nebulizer, and this method also comprises the described nebulizer of obstruction.
Administration assembly has used the reciprocating pump pressure head of the axially-movable that a weight alleviates greatly in the pipe of the present invention, and this pump head has been used for patient's nasal cavity is supplied with the suspended particulates medicine for many years in ten million quantitative atomizing pump of manual reciprocating type nasal cavity.As a result, the pump head finished product quantity that can buy is actually greatly, therefore can greatly reduce cost.In addition, under a large amount of occasions, simple pump head mechanism can guarantee its precision and reliability.Because cost is lower, so administration assembly is easy to adopt disposable products, thereby further strengthened health and safety.The utmost point light weight that pump head had helps it and uses with mobile topping-up pump.Because pump head needs simple line movement to produce accurate output, therefore, a large amount of linear reciprocating drivers are suitable for using with the topping-up pump of the reciprocating pump pressure head that axially-movable is housed.Used the topping-up pump of described pump head that roughly successive flow of liquid or fast injection can be provided.And it can also carry Fluid Volume very accurately during whole a large amount of pumps head action.
Brief description of the drawings
Fig. 1 is the sketch map that is used to illustrate topping-up pump in the pipe of the present invention;
Fig. 2 is the perspective view that has utilized embodiment of topping-up pump in the pipe of the present invention of an injection liquid reservoir;
Fig. 3 is the pumping mechanism of the interior topping-up pump of pipe among Fig. 2 and the perspective view of administration assembly;
Fig. 4 is used for the decomposition view of the typical shaft of topping-up pump in the pipe of the present invention to reciprocal pump head.
The detailed description of most preferred embodiment
Fig. 1 has schematically provided topping-up pump 10 in a kind of pipe of the present invention.Topping-up pump 10 comprises a pump housing 12 and an administration assembly 14 in the pipe.
The pump housing 12 comprises that one is used for encapsulating the housing 36 of pump electronic unit and driving device.One controller 38 that is used for the work of control pump driving device is set in housing.Controller 38 preferably includes micromessage processor able to programme and the memorizer with selection function, so that control and the work of monitoring pumping mechanism and the selection delivery profile of the medicinal liquid that control is used for the patient.In addition, as skilled in the art to understand, multiple logic circuit can be realized the function of controller, but the same with micromessage processor and supporting memorizer, and these circuit do not have the advantage of reconfiguration procedure.
The pump housing 12 also comprises a plurality of pick offs.One position sensor 54 links to each other with described controller by adapter 56, and it is used for described controller is sent explanation pump head 16 correct localized signal in receptor 53.Follow procedure is set described controller, if so that do not receive signal, then can provide a suitable warning signal to user.
One outlet pressure sensor 58 links to each other with described controller by adapter 60.Described outlet pressure sensor controllably links to each other with the outlet tube 22 of administration assembly 14, the pressure increment of be used to detect in outlet tube 22 inside, the expression downstream being stopped up.One inlet pressure transducer 162 is connected to described controller by adapter 64 and controllably links to each other with input pipe 20, so that survey the pressure reduction of representing to lack pump head 16 upstream fluid in input pipe 20, it may produce when liquid reservoir 18 emptyings.Controller 38 is connected to power supply 68 by adapter 66.Power supply 68 can adopt battery or to comprise the wiring of the standard ac output end of suitable AC/DC transducer.Another pick off that setting links to each other with power supply is surveyed power supply status.All the sensors all provides signal to controller 38 through their lines separately.The program of correct setting controller 38 is to receive and to handle the sensor signal of its reception.Correct image or warning signal are transported to user by the display 70 that is connected to described controller with line 72.Except the display alarm signal, described display is also with useful information, and as the speed of pump, pump output, delivery profile etc. are delivered to the user of pump.Described display can adopt traditional liquid crystal dot matrix display.User input 74 is by line 76 and described controller coupling.User is by the operation of described input control pump.The various input signals of controller 38 responses, thereby control pumping mechanism.
Topping-up pump 10 can be designed as disposable, simultaneously administration assembly 14 by permanent seal in housing 36 inside.Obviously, this embodiment need not use location pick off 54.On the other hand, the pump housing is can be reusable, and administration assembly 14 then is disposable.
The example of the syringe pump 80 of the interior topping-up pump of pipe as shown in Figure 2 among the present invention.Syringe pump 80 has a stiff case 82, and this housing includes the shell 84 of a canned pump mechanical part and electronic section.In the lid 90 of shell 84, be provided with just like traditional liquid crystal dot matrix display such display 86 and a plurality of input 88.Described housing also defines an elongated shape receptor 92 that is used to hold administration assembly 14.In this embodiment, administration assembly 14 comprises that a syringe 94 and that is connected to an actual reciprocating pump pressure head 98 by input pipe 96 is connected to the outlet tube 100 of pump head outlet in the pump head 98.
Syringe 94 can adopt traditional structure well known in the art.Syringe 94 also comprises a fluid cylinder 102, and it has an open type far-end 104 that is used to hold plunger 106.The near-end of fluid cylinder 102 defines the outlet 108 that is used for the contained liquid of fluid cylinder 102.Such as easily understood by the skilled person, liquid described fluid cylinder can be sucked through exporting 108 by extracting plunger 106 out, or described liquid can be discharged by inserting piston.
Fig. 3 illustrates in greater detail the administration assembly 14 and the pump machanism in syringe downstream.Axially reciprocating pump pressure head 98 comprises the pump head inlet 110 and the pump head outlet 112 of coaxial setting, and input pipe 96 is connected to pump head inlet 110, and outlet tube 100 is connected to pump head outlet 112.Comprise that at the axial reciprocating pump pressure head 98 shown in the exploded view of Fig. 3 one defines the fluid cylinder 114 of a pump chamber and a piston 116 (referring to Fig. 3), the exhaust position and the recharging of maximum pump cubical content of the minimum pump chamber amount of described piston in fluid cylinder 114 reciprocatingly slide between the position.Piston 116 is driven by connecting rod 118, and connecting rod 118 also defines the outlet 112 of pump head.Described connecting rod also comprises a pushing dish 120, as hereinafter being described in more detail, is used to promote the action of connecting rod.As shown in Figure 4, pushing dish 120 is and connecting rod 118 isolating independent components.
Described administration assembly controllably links to each other with the driving device of pump by a fixed block 126.Fixed block 126 defines a support 128, and it is used to hold the fluid cylinder 114 of axial reciprocating pump pressure head 98.Be provided with one in the groove 130 in being defined in fixed block 126 and promote to catch plate adapter (pushcapture plate adapter) 124.One cam-follower 132 is fastened on recess 134 inside of fixed block 126, and can place the cam 138 reciprocal linear driving of the axle 140 of motor 142 along direction shown in the arrow 136, by an off-centre.Can learn obviously that from Fig. 3 when axle 140 rotated, by cam-follower and the engagement of cam 138 edges, pump head 98 axis that cam-follower 132 moves were vertically made linear reciprocal movement.Can utilize a unshowned spring bias voltage cam-follower to contact with a cam.The far-end of cam-follower 132 limits a groove 144, and it has held the connecting rod 118 of administration assembly and has reacted on pushing dish 120 with axial driving pump pressure head 98.
Fig. 3 is the reciprocating pump pressure head 98 of a typical axially-movable.Pump head 98 comprises that an inside is provided with the fluid cylinder 114 of piston 116.Particularly, spheroid 146 is contained in the fluid cylinder 114 and is resisted against the part 148 that diameter reduces in the fluid cylinder 114.Subsequently, spring 150 is arranged in the fluid cylinder, and is resisted against and divides 148 flange (not shown) in the fluid cylinder, in abutting connection with reduced diameter portion.Then, bar 152 is inserted in the fluid cylinder vertically and is connected the far-end of spring 150.The same with connecting rod 118, piston 116 is arranged on the spring 150.Apertures 154 in the connecting rod 118 define the conduit that liquid is delivered to pump head outlet 112, and lid 156 engages with flange 158 on the liquid 114, so that each parts on the pump head 98 of axially reciprocating remain on their rigging position.Pushing dish 120 has held the far-end of connecting rod 118 in the hole 159 of termination pump head outlet 118.Axially connecting rod 118 is pressed into by pushing dish 120 and makes piston 116 move to exhaust position, pump head is through the fluid cylinder pumping liquid.By reducing the axial force on the connecting rod 118, spring 150 biases piston 116 are to the position of recharging.When force piston from exhaust position when move in the loading position, spheroid 146 has sealed pump discharge 110 at reduced part 148 places.Therefore, the liquid in fluid cylinder is discharged by pump discharge.When spring biased plunger during to the loading position, the confining pressure on the spheroid 146 weakens and fluid inflow pump inlet 110.Can prevent that by an one way stop peturn valve (not shown) liquid from flowing into the pump discharge 112 of connecting rod 118.
Pump head is discharged stroke and be can be the full discharging stroke with a series of stepping parts, maybe can adopt the complete continuously discharging stroke with fast return function so that roughly successive flow of liquid to be provided so that quick administration (bolus dosage) in a small amount to be provided.As skilled in the art to understand, cam face can be designed to allow that spring in the pump head mechanism is instantaneous substantially that pump plunger is moved to the position of recharging from exhaust position, thus another discharge unit of beginning pumping stroke.
Though not shown, can adopt a standard IV bag to replace syringe 94.Obviously, this requirement improves outer rigid housing 82.On the other hand, the supply source of liquid can be away from the shell of pump, and the input pipe 96 through linking to each other with a long-range liquid reservoir is supplied to administration assembly 14.
Topping-up pump of the present invention and administration assembly have used a kind of standarizing pump pressure head, and by a large amount of quantitative as nasal cavity, this pump head pump head has proved accurately and be very reliable.As a result, under the situation that does not impair accuracy or reliability, make the cost of administration assembly reduce to minimum.The simple linear action of pump head can comprise the mechanism controls of very simple, inexpensive and high reliability by multiple multi-form reciprocal linear driving device.Administration assembly can adopt a kind of pump assembly, and it comprises the preset program micromessage processor that can inject with different delivery profile.
Claims (20)
1. administration assembly in the pipe, it comprises:
The reciprocating pump pressure head of one axially-movable, it has pump head inlet and pump head outlet;
One has the input pipe of first and second ends, and described first end is suitable for linking to each other with a liquid reservoir is liquid with described liquid linking to each other of pump head inlet, described second end; And
One has the outlet tube of first and second ends, and described first end is suitable for linking to each other with a patient blood vessel is liquid with described liquid linking to each other of pump head outlet, described second end.
2. administration assembly in the pipe according to claim 1, it is characterized in that: the reciprocating pump pressure head of described axially-movable comprises that one is slidably received within the piston in the fluid cylinder, described piston can be in fluid cylinder the exhaust position and the axially-movable between the position of recharging, liquid is sucked described pump head inlet and from described pump head outlet drain.
3. administration assembly in the pipe according to claim 2, it is characterized in that: the reciprocating pump pressure head of described axially-movable also comprises a control valve that links to each other with described fluid cylinder liquid state, in order to move to when recharging the position from exhaust position when described piston, make liquid stream only enter described fluid cylinder from described pump head inlet, and when described piston when the position of recharging moves to exhaust position, liquid stream is only discharged from described pump head outlet.
4. administration assembly in the pipe according to claim 2, it is characterized in that: the reciprocating pump pressure head of described axially-movable comprises that also one is assembled to the connecting rod of described piston, be used at the exhaust position and the mobile described piston between the position that recharges, described connecting rod engages with a linear reciprocating drive unit.
5. administration assembly in the pipe according to claim 1, it is characterized in that: it also comprises a liquid reservoir that links to each other with second end liquid state in the described input pipe, described liquid reservoir comprises that one has the syringe of fluid cylinder, described fluid cylinder has second end that an open type first end and defines liquid outlet, and being slidably received within the piston of described open type first end, second end of described input pipe links to each other with the liquid outlet of described fluid cylinder.
6. administration assembly in the pipe according to claim 1 is characterized in that: the pump head inlet and the pump head outlet of described reciprocating pump pressure head axially are provided with along described pump head.
7. topping-up pump in the pipe, it comprises:
The reciprocating pump pressure head of one axially-movable, it has pump head inlet and pump head outlet;
One housing, it has the pump head receptor that holds described pump head;
One liquid reservoir;
One has the input pipe of first and second ends, described first end and described liquid linking to each other of pump head inlet, and described second end links to each other with a liquid reservoir is liquid;
One has the outlet tube of first and second ends, and described first end is suitable for linking to each other with a patient blood vessel is liquid with described liquid linking to each other of pump head outlet, described second end; And
One linear reciprocating drive unit, it controllably links to each other with pump head in described housing.
8. topping-up pump in the pipe according to claim 7, it is characterized in that: described liquid reservoir is installed in described enclosure interior.
9. topping-up pump in the pipe according to claim 7, it is characterized in that: described liquid reservoir comprises that one has the syringe of fluid cylinder, described fluid cylinder has second end that an open type first end and defines liquid outlet, and the piston that is slidably received within described open type first end, second end of described input pipe links to each other with the liquid outlet of described fluid cylinder.
10. topping-up pump in the pipe according to claim 7, it is characterized in that: described liquid reservoir comprises an IV bag.
11. topping-up pump in the pipe according to claim 7, it is characterized in that: the reciprocating pump pressure head of described axially-movable comprises that one slidably is contained in the piston in the fluid cylinder, described piston can be in fluid cylinder the exhaust position and the axially-movable between the position of recharging, liquid is sucked described pump intake and from described pump drain; Reach a control valve that links to each other with described fluid cylinder liquid state, in order to move to when recharging the position from exhaust position when described piston, make liquid stream only enter fluid cylinder from described pump head inlet, and when described piston when the position of recharging moves to exhaust position, liquid stream is only discharged from described pump head outlet, and a connecting rod that is assembled to described piston, being used between described exhaust position and loading position, moving described piston, described connecting rod engages with described linear reciprocating drive unit.
12. topping-up pump in the pipe according to claim 7, it is characterized in that: described linear reciprocating drive unit comprises that one has the motor of a rotating driveshaft and the rotating mechanism of converter,linear, it controllably links to each other with the reciprocating pump pressure head of described driving shaft and axially-movable, so that control described pump head.
13. topping-up pump in the pipe according to claim 12, it is characterized in that: the rotating mechanism of described converter,linear comprises that one has the cam at edge, described cam off-centre is fixed on the described driving shaft, an and cam-follower, it controllably engages the also biased described cam edge that contacts with described cam edge, therefore, when described cam rotates, but described cam-follower linear reciprocal movement, described cam-follower is connected so that drive described pump head with the reciprocating pump pressure head of axially-movable.
14. topping-up pump in the pipe according to claim 7, it also comprises: the controller that links to each other with described reciprocal linear driving device controllably, operate in order to the preset program of controlling described pump head.
15. topping-up pump in the pipe according to claim 14, it also comprises: a pressure transducer that controllably links to each other and be of coupled connections with described controller with described outlet tube, and in order to the detection downstream block.
16. topping-up pump in the pipe according to claim 14, it also comprises: an encoder that controllably links to each other and be of coupled connections with described controller with described linear actuating device, and in order to described controller is sent the signal of representing pump delivery.
17. one kind the patient managed in the method for liquid medicine injection, it comprises;
The reciprocating pump pressure head of one axially-movable is set, and this pump head has pump head inlet and pump head outlet;
One input pipe and an outlet tube are set, and described input pipe and outlet tube all have first and second ends;
Make first end and described liquid linking to each other of pump head inlet of described input pipe, and second end of described input pipe links to each other with a liquid reservoir is liquid;
Make first end and described liquid linking to each other of pump head outlet of described outlet tube, and its second end links to each other with a patient blood vessel is liquid;
One reciprocal linear driving device is controllably linked to each other with described pump head; And
Drive described reciprocal linear driving device.
18. method according to claim 17, it also comprises: an encoder that controllably links to each other with described reciprocal linear driving device is set, so that produce a signal according to above-mentioned each back and forth operation;
One controller that links to each other with described encoder is set, in order to receive signal for described reciprocal linear driving device; And
Set the program of described controller, in order to the speed of actions of controlling described linear actuating device and the output that calculates pump head according to the signal of accepting from described encoder.
19. method according to claim 17 is characterized in that: the reciprocating pump pressure head of described axially-movable comprises the quantitative atomizing pump of nasal cavity mechanism, and this mechanism comprises a nebulizer, and described method also comprises the obstruction nebulizer.
20. method according to claim 17, it also comprises: a syringe as liquid reservoir is set, described syringe is a fluid cylinder, and it has second end that an open type first end and defines liquid outlet, and the plunger that is contained in described open type first end;
Second end of described input pipe is linked to each other with the liquid outlet of described syringe fluid cylinder;
By driving described reciprocal linear driving device, in the liquid outlet generation negative pressure of described syringe, so that from described syringe, extract liquid out.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24337399A | 1999-02-01 | 1999-02-01 | |
| US09/243,373 | 1999-02-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1295486A true CN1295486A (en) | 2001-05-16 |
Family
ID=22918508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN99804498A Pending CN1295486A (en) | 1999-02-01 | 1999-12-03 | Metered dose infusion pump and method |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1067975A1 (en) |
| JP (1) | JP2002535554A (en) |
| KR (1) | KR20010042349A (en) |
| CN (1) | CN1295486A (en) |
| AR (1) | AR022464A1 (en) |
| AU (1) | AU3112100A (en) |
| BR (1) | BR9909316A (en) |
| CA (1) | CA2323201A1 (en) |
| CO (1) | CO5221118A1 (en) |
| HU (1) | HUP0102219A3 (en) |
| PL (1) | PL343117A1 (en) |
| TR (1) | TR200002802T1 (en) |
| TW (1) | TW418102B (en) |
| WO (1) | WO2000044420A1 (en) |
| ZA (1) | ZA200004468B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104033348A (en) * | 2014-06-09 | 2014-09-10 | 四川大学 | Digital quantitative continuous liquid injection pump |
| CN112283061A (en) * | 2020-10-29 | 2021-01-29 | 上海大学 | Micro-fluidic passive pump based on soluble gas dissolution driving |
| CN112472979A (en) * | 2020-12-02 | 2021-03-12 | 中国人民解放军陆军军医大学第一附属医院 | Micro-administration equipment for infants |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100473363B1 (en) * | 2000-10-28 | 2005-03-07 | 김용년 | Injector |
| US9033920B2 (en) | 2003-10-02 | 2015-05-19 | Medtronic, Inc. | Determining catheter status |
| US9138537B2 (en) | 2003-10-02 | 2015-09-22 | Medtronic, Inc. | Determining catheter status |
| EP1535637A1 (en) * | 2003-11-28 | 2005-06-01 | Woo Young Medical Co., Ltd. | Automatic dose infusion apparatus |
| US9044537B2 (en) | 2007-03-30 | 2015-06-02 | Medtronic, Inc. | Devices and methods for detecting catheter complications |
| KR100924947B1 (en) | 2007-08-09 | 2009-11-06 | 주식회사 씨피엘 | Medical Pump |
| WO2011044294A1 (en) * | 2009-10-06 | 2011-04-14 | Flex Partners, Inc. | Precision fluid delivery systems |
| WO2014104857A1 (en) * | 2012-12-28 | 2014-07-03 | 메디칸(주) | Static pressure and metering pump |
| KR102378501B1 (en) * | 2019-12-17 | 2022-03-25 | 이오플로우(주) | Drug injection device, driving time symmetry method and recording medium using driving time symmetry algorithm |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2300576A1 (en) * | 1975-02-12 | 1976-09-10 | Giraux Jean | Cassette form peristaltic pump - has feed tube resting on base between cartridge sides, pressed by cam operated leaf spring |
| US5009641A (en) * | 1988-12-02 | 1991-04-23 | Pacesetter Infusion, Ltd. | Patient-controlled analgesia security attachment for a medication infusion system |
| US5039279A (en) * | 1990-03-15 | 1991-08-13 | Abbott Laboratories | Sensor for detecting fluid flow from a positive displacement pump |
| US5433191A (en) | 1992-05-15 | 1995-07-18 | Habley Medical Technology Corp. | Medication sprayer |
| US5807075A (en) * | 1993-11-23 | 1998-09-15 | Sarcos, Inc. | Disposable ambulatory microprocessor controlled volumetric pump |
| US5632606A (en) * | 1993-11-23 | 1997-05-27 | Sarcos Group | Volumetric pump/valve |
| US5582593A (en) * | 1994-07-21 | 1996-12-10 | Hultman; Barry W. | Ambulatory medication delivery system |
-
1999
- 1999-12-03 AU AU31121/00A patent/AU3112100A/en not_active Abandoned
- 1999-12-03 KR KR1020007010914A patent/KR20010042349A/en not_active Application Discontinuation
- 1999-12-03 JP JP2000595722A patent/JP2002535554A/en active Pending
- 1999-12-03 CN CN99804498A patent/CN1295486A/en active Pending
- 1999-12-03 WO PCT/US1999/028885 patent/WO2000044420A1/en not_active Application Discontinuation
- 1999-12-03 BR BR9909316-2A patent/BR9909316A/en not_active Application Discontinuation
- 1999-12-03 CA CA002323201A patent/CA2323201A1/en not_active Abandoned
- 1999-12-03 PL PL99343117A patent/PL343117A1/en unknown
- 1999-12-03 HU HU0102219A patent/HUP0102219A3/en unknown
- 1999-12-03 TR TR2000/02802T patent/TR200002802T1/en unknown
- 1999-12-03 EP EP99965142A patent/EP1067975A1/en not_active Withdrawn
- 1999-12-24 TW TW088122866A patent/TW418102B/en not_active IP Right Cessation
-
2000
- 2000-01-25 CO CO00003904A patent/CO5221118A1/en not_active Application Discontinuation
- 2000-01-31 AR ARP000100416A patent/AR022464A1/en unknown
- 2000-08-29 ZA ZA200004468A patent/ZA200004468B/en unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104033348A (en) * | 2014-06-09 | 2014-09-10 | 四川大学 | Digital quantitative continuous liquid injection pump |
| CN112283061A (en) * | 2020-10-29 | 2021-01-29 | 上海大学 | Micro-fluidic passive pump based on soluble gas dissolution driving |
| CN112472979A (en) * | 2020-12-02 | 2021-03-12 | 中国人民解放军陆军军医大学第一附属医院 | Micro-administration equipment for infants |
Also Published As
| Publication number | Publication date |
|---|---|
| AU3112100A (en) | 2000-08-18 |
| WO2000044420A1 (en) | 2000-08-03 |
| HUP0102219A2 (en) | 2001-10-28 |
| BR9909316A (en) | 2000-11-21 |
| CO5221118A1 (en) | 2002-11-28 |
| CA2323201A1 (en) | 2000-08-03 |
| PL343117A1 (en) | 2001-07-30 |
| TW418102B (en) | 2001-01-11 |
| KR20010042349A (en) | 2001-05-25 |
| HUP0102219A3 (en) | 2001-12-28 |
| EP1067975A1 (en) | 2001-01-17 |
| ZA200004468B (en) | 2001-03-06 |
| TR200002802T1 (en) | 2000-12-21 |
| JP2002535554A (en) | 2002-10-22 |
| AR022464A1 (en) | 2002-09-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4382753A (en) | Nonpulsating IV pump and disposable pump chamber | |
| US4391600A (en) | Nonpulsating IV pump and disposable pump chamber | |
| US4410322A (en) | Nonpulsating TV pump and disposable pump chamber | |
| US4236880A (en) | Nonpulsating IV pump and disposable pump chamber | |
| CN100391553C (en) | Ambulatory infusion membrane pump | |
| US4919649A (en) | Fluid delivery system | |
| EP1556104B1 (en) | Medical cassette pump with single force sensor to determine the operating status | |
| US7360999B2 (en) | Means for using single force sensor to supply all necessary information for determination of status of medical pump | |
| EP0319275B1 (en) | Patient-side occlusion detection system for a medication infusion system | |
| CA1127491A (en) | Medical infusion system | |
| US5244463A (en) | Programmable infusion pump | |
| CN1295486A (en) | Metered dose infusion pump and method | |
| US20090143726A1 (en) | Means for using single force sensor to supply all necessary information for determination of status of medical pump | |
| US20080167641A1 (en) | Medical Device Adapted To Detect Disengagement Of A Transcutaneous Device | |
| CN1938061A (en) | Actuator system comprising detector means | |
| CN103415310A (en) | Methods and systems for dosing medicament | |
| CN1938060A (en) | Actuator system comprising lever mechanism | |
| WO2008144398A2 (en) | Pump module for use in a medical fluid dispensing system | |
| EP0416910A2 (en) | Ultrasonic transducer electrical interface assembly | |
| US20150190572A1 (en) | Trace Control System for an Intravenous Drip | |
| CN214970240U (en) | Infusion device | |
| RU109664U1 (en) | DEVICE FOR SUBMITTING MICRO QUANTITIES OF THE CURRENT ENVIRONMENT | |
| US20240082486A1 (en) | Drug delivery device | |
| JPH028149B2 (en) | ||
| CZ20003589A3 (en) | Intravascular application kit, intravascular infusion syringe and intravascular liquid infusion process |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |