Search Images Maps Play YouTube Gmail Drive Calendar More »
Sign in
Screen reader users: click this link for accessible mode. Accessible mode has the same essential features but works better with your reader.

Patents

  1. Advanced Patent Search
Publication numberCN1295486 A
Publication typeApplication
Application numberCN 99804498
PCT numberPCT/US1999/028885
Publication date16 May 2001
Filing date3 Dec 1999
Priority date1 Feb 1999
Also published asCA2323201A1, EP1067975A1, WO2000044420A1
Publication number99804498.9, CN 1295486 A, CN 1295486A, CN 99804498, CN-A-1295486, CN1295486 A, CN1295486A, CN99804498, CN99804498.9, PCT/1999/28885, PCT/US/1999/028885, PCT/US/1999/28885, PCT/US/99/028885, PCT/US/99/28885, PCT/US1999/028885, PCT/US1999/28885, PCT/US1999028885, PCT/US199928885, PCT/US99/028885, PCT/US99/28885, PCT/US99028885, PCT/US9928885
Inventors史蒂芬O罗斯
Applicant巴克斯特国际公司
Export CitationBiBTeX, EndNote, RefMan
External Links: SIPO, Espacenet
Metered dose infusion pump and method
CN 1295486 A
Abstract  translated from Chinese
一种管内给药组件(14)包括一轴向运动的往复式泵压头(98),其具有一泵压头入口(110)和泵压头出口(112)。 A dosing assembly inner tube (14) includes an axial movement of the reciprocating pump head (98), having a pump head inlet (110) and the pump head outlet (112). 输入管(96)具有安装在泵压头入口(110)的第一端和适于与一贮液器相连的第二端。 Inlet tube (96) having a first end and a second end adapted to be connected with a liquid reservoir mounted on the pump head inlet (110). 一输出管(100)具有与泵压头出口(112)相连的第一端及适于与患者血管液态相连的第二端。 An output tube (100) having a first end and a second end adapted to patients with vascular liquid connected to the pump head outlet (112) is connected. 轴向运动的往复式泵压头(98)的泵压头入口(110)和泵压头出口(118)沿泵压头(98)轴向设置。 Axial movement of the reciprocating pump head (98) of the pump head inlet (110) and the pump head outlet (118) disposed axially along the pump head (98). 管内注液泵(80)装配有给药组件(14)且包括一可控制地与泵压头(98)相连的线性往复驱动装置。 Inner tube injection pump (80) equipped with a dosing assembly (14) and comprises a controllably with the pump head (98) connected to the linear reciprocating drive means. 贮液器可采用注射器(94),通过在注射器出口(108)处产生负压力从注射器泵送液体。 The reservoir may be a syringe (94), by generating a negative pressure in the syringe outlet (108) at the pumped fluid from the syringe. 一种液体管内注射的方法使用了给药组件(14)和线性往复驱动装置(132)。 Within a liquid injection tube method using a dosing assembly (14) and a linear reciprocating drive means (132).
Claims(20)  translated from Chinese
1. 1. 一种管内给药组件,其包括:一轴向运动的往复式泵压头,其具有一泵压头入口和一泵压头出口;一具有第一和第二端的输入管,所述第一端与所述泵压头入口液态相连,所述第二端适于与一贮液器液态相连;及一具有第一和第二端的输出管,所述第一端与所述泵压头出口液态相连,所述第二端适于与一患者的血管液态相连。 An inner tube administration assembly comprising: an axially reciprocating pump head movement, having a pump head inlet and a pump head outlet; having first and second ends of the inlet tube, the first end of the pump head is connected to the liquid inlet, said second end adapted for connection with a reservoir of liquid; and having first and second ends of the outlet tube, said first end connected to said pump head outlet liquid connected, said second end adapted for connection with a patient's blood vessel liquid.
2. 2. 根据权利要求1所述的管内给药组件,其特征在于:所述轴向运动的往复式泵压头包括一可滑动地容纳在一液缸中的活塞,所述活塞可在液缸内的排放位置和再装填位置之间轴向运动,以将液体吸入所述泵压头入口并从所述泵压头出口排出液体。 Administered according to the inner tube assembly as claimed in claim 1, wherein: the axial movement of the reciprocating pump head comprises a slidably received in a cylinder in a piston cylinder in fluid discharge position and axial movement between the refill position, to the liquid suction inlet of the pump head and the liquid is discharged from the pump head outlet.
3. 3. 根据权利要求2所述的管内给药组件,其特征在于:所述轴向运动的往复式泵压头还包括一与所述液缸液态相连的控制阀,用以当所述活塞从排放位置移动至再装填位置时,使液流仅从所述泵压头入口进入所述液缸,且当所述活塞从再装填位置移动至排放位置时,使液流仅从所述泵压头出口排出。 Administered according to the inner tube assembly as claimed in claim 2, wherein: the axial movement of the reciprocating pump head further comprises a control valve and the hydraulic cylinder connected to a liquid, for when the piston moves from the discharge position When moved to the refill position, liquid flow only from the pump head inlet into said cylinder, and when said piston is moved from the refill position to the discharge position, so that the liquid flow only from the pump head outlet discharge.
4. 4. 根据权利要求2所述的管内给药组件,其特征在于:所述轴向运动的往复式泵压头还包括一装配至所述活塞的连杆,用于在排放位置和再装填位置之间移动所述活塞,所述连杆与一线性往复驱动装置接合。 Administered according to the inner tube assembly as claimed in claim 2, wherein: the axial movement of the reciprocating pump head further comprises a linkage assembly to said piston for movement between the discharge position and the refill position moving said piston, said connecting rod and a linear reciprocating drive means engagement.
5. 5. 根据权利要求1所述的管内给药组件,其特征在于:其还包括一与所述输入管中第二端液态相连的贮液器,所述贮液器包括一具有液缸的注射器,所述液缸具有一开式第一端和一限定了液体出口的第二端,及可滑动地容纳在所述开式第一端的活塞,所述输入管的第二端与所述液缸的液体出口相连。 Administered according to the inner tube assembly as claimed in claim 1, characterized in that: it further comprises a reservoir tube with said second input terminal connected to the liquid, the reservoir comprises a syringe having a cylinder, the said hydraulic cylinder having an open first end and a second end defining a liquid outlet, and slidably received in said open first end of the piston, the input end and the second tube cylinder The liquid is connected to the outlet.
6. 6. 根据权利要求1所述的管内给药组件,其特征在于:所述往复泵压头的泵压头入口和泵压头出口沿所述泵压头轴向设置。 Administered according to the inner tube assembly as claimed in claim 1, wherein: said reciprocating pump head pump head inlet and the pump head outlet of the pump head along the axial direction.
7. 7. 一种管内注液泵,其包括:一轴向运动的往复式泵压头,其具有一泵压头入口和一泵压头出口;一壳体,其具有容纳所述泵压头的泵压头接收器;一贮液器;一具有第一和第二端的输入管,所述第一端与所述泵压头入口液态相连,所述第二端与一贮液器液态相连;一具有第一和第二端的输出管,所述第一端与所述泵压头出口液态相连,所述第二端适于与一患者的血管液态相连;及一线性往复驱动装置,其在所述壳体内与泵压头可控制地相连。 An inner tube injection pump, comprising: an axial reciprocating movement of the pump head, the pump head having a pump head inlet and an outlet; a housing which accommodates the pump head having a pump pressure first receiver; an accumulator; having first and second ends of the inlet tube, the first end of the pump head with a liquid inlet connected to said second end connected to a reservoir of liquid; having first and second ends of the outlet tube, said first end connected to said pump head outlet liquid, said second end adapted for connection with a patient's blood vessel liquid; and a linear reciprocating drive means, which in the the housing and the pump head can be connected controllably.
8. 8. 根据权利要求7所述的管内注液泵,其特征在于:所述贮液器安装在所述壳体内部。 According to claim 7 within a tube injection pump, wherein: said reservoir is mounted inside the housing.
9. 9. 根据权利要求7所述的管内注液泵,其特征在于:所述贮液器包括一具有液缸的注射器,所述液缸具有一开式第一端和一限定了液体出口的第二端,以及可滑动地容纳在所述开式第一端的活塞,所述输入管的第二端与所述液缸的液体出口相连。 According to claim 7 of the inner tube injection pump, characterized in that: the reservoir comprises a syringe having a cylinder, said cylinder having an open first end and a liquid outlet defining a second end , and slidably received in said open first end of the piston, the second end of said input tube and the liquid outlet of the cylinder is connected.
10. 10. 根据权利要求7所述的管内注液泵,其特征在于:所述贮液器包括一Ⅳ袋。 Injection pump according to claim 7, wherein the inner tube, characterized in that: the reservoir comprises a pouch Ⅳ.
11. 11. 根据权利要求7所述的管内注液泵,其特征在于:所述轴向运动的往复式泵压头包括一可滑动容纳在一液缸中的活塞,所述活塞可在液缸内的排放位置和再装填位置之间轴向运动,以将液体吸入所述泵入口并从所述泵排出液体;及一与所述液缸液态相连的控制阀,用以当所述活塞从排放位置移动至再装填位置时,使液流仅从所述泵压头入口进入液缸,且当所述活塞从再装填位置移动至排放位置时,使液流仅从所述泵压头出口排出,及一装配至所述活塞的连杆,用于在所述排放位置和装填位置之间移动所述活塞,所述连杆与所述线性往复驱动装置接合。 According to claim 7 of the inner tube injection pump, characterized in that: the axial movement of the reciprocating pump head comprises a slidably accommodated in a cylinder in a piston cylinder can be discharged in liquid axial movement between the position and the refill position, to the liquid suction inlet of the pump and the liquid is discharged from said pump; and control valve with said hydraulic cylinder connected to a liquid, for when the piston is moved from the discharge position when to refill position, liquid flow only from the pump head inlet into the cylinder, and when the piston is moved from the loaded position to the discharge position again, so that the liquid flow only from the pump head outlet, and an assembly to said piston rod for movement between the loading position and the discharge position of the piston, the connecting rod with the linear reciprocating drive means engagement.
12. 12. 根据权利要求7所述的管内注液泵,其特征在于:所述线性往复驱动装置包括一具有一旋转驱动轴的电动机及线性转换器的旋转机构,其可控制地与所述驱动轴和轴向运动的往复式泵压头相连,以便控制所述泵压头。 According to claim 7 of the inner tube injection pump, wherein: said driving means comprises a linear reciprocating rotation of the rotary mechanism having a linear motor and the drive shaft of the converter, which can be controlled with the drive shaft and the shaft is connected to the ram movement of the reciprocating pump, so as to control the pump head.
13. 13. 根据权利要求12所述的管内注液泵,其特征在于:所述线性转换器的旋转机构包括一具有边缘的凸轮,所述凸轮偏心固定于所述驱动轴上,及一凸轮随动件,其可控制地与所述凸轮边缘接合并被偏压接触所述凸轮边缘,因此,当所述凸轮转动时,所述凸轮随动件可线性往复运动,所述凸轮随动件与轴向运动的往复式泵压头相连接以便驱动所述泵压头。 Injection pump according to claim 12, wherein the inner tube, wherein: said rotating means comprises a linear transducer having a cam edge, said eccentric cam fixed to the drive shaft, and a cam follower, which may be controllably engaged with said cam and biased into contact with the edge of the cam edge, and therefore, when the cam is rotated, the cam follower is linearly reciprocated, the cam follower and axial movement reciprocating pump head connected to drive said pump head.
14. 14. 根据权利要求7所述的管内注液泵,其还包括:可控制地与所述往复线性驱动装置相连的控制器,用以控制所述泵压头的预定程序操作。 According to claim 7 of the inner tube injection pump, further comprising: controllably controller with the reciprocating linear drive means connected to control the pump head of a predetermined program operation.
15. 15. 根据权利要求14所述的管内注液泵,其还包括:一可控制地与所述输出管相连并与所述控制器耦合连接的压力传感器,用以探测下游阻塞。 According to claim 14 of the inner tube injection pump, further comprising: a controllably coupled with said output pipe coupled to the controller and coupled to said pressure sensor for detecting a downstream obstruction.
16. 16. 根据权利要求14所述的管内注液泵,其还包括:一可控制地与所述线性驱动装置相连并与所述控制器耦合连接的编码器,用以对所述控制器发出表示泵输出量的信号。 According to claim 14 of the inner tube injection pump, further comprising: a controllably connected to said linear drive means coupled with said controller and an encoder connected to said controller to issue an output indicating that the pump semaphore.
17. 17. 一种对患者进行管内注射药液的方法,其包括;设置一轴向运动的往复式泵压头,该泵压头具有一泵压头入口和一泵压头出口;设置一输入管和一输出管,所述输入管和输出管均具有第一和第二端;使所述输入管的第一端与所述泵压头入口液态相连,且所述输入管的第二端与一贮液器液态相连;使所述输出管的第一端与所述泵压头出口液态相连,且其第二端与一患者的血管液态相连;使一往复线性驱动装置与所述泵压头可控制地相连;以及驱动所述往复线性驱动装置。 A patient of the inner tube injects a drug solution, comprising; disposed axially reciprocating pump head of a movement, the pump head having a pump head inlet and a pump head outlet; provided an inlet tube and a output pipe, said inlet and outlet tubes each having first and second ends; said inlet pipe and said first end of the pump head is connected to the liquid inlet, and a second end of said inlet pipe and a reservoir liquid dispenser is connected; said first end of the delivery pipe with the liquid outlet of the pump head is connected, and a second end connected to a blood vessel of liquid; make a reciprocating linear drive means and the pump head can be control connected to ground; and driving means for driving said reciprocating linear.
18. 18. 根据权利要求17所述的方法,其还包括:设置一可控制地与所述往复线性驱动装置相连的编码器,以便根据上述每次往复操作产生一信号;设置一与所述编码器相连的控制器,用以接收对于所述往复线性驱动装置的信号;及设定所述控制器的程序,用以控制所述线性驱动装置的动作速率并根据从所述编码器接受的信号来计算泵压头的输出量。 A method according to claim 17, further comprising: providing a can with the reciprocating linear drive means for controllably encoder connected to generate a signal in response to the above-described operation each time the shuttle; provided with an encoder coupled to the a controller for receiving the linear reciprocating driving means for the signal; and setting the controller program, for controlling the rate of operation of said linear drive means and from said encoder based on received signals to calculate the pump output indenter.
19. 19. 根据权利要求17所述的方法,其特征在于:所述轴向运动的往复式泵压头包括一鼻腔定量喷雾泵机构,该机构包括一雾化器,所述方法还包括阻塞雾化器。 The method according to claim 17, wherein: said axial reciprocating movement of the pump head comprises a nasal metered dose pump mechanism which comprises a nebulizer, the method further comprises blocking the atomizer.
20. 20. 根据权利要求17所述的方法,其还包括:设置一作为贮液器的注射器,所述注射器为一液缸,其具有一开式第一端和一限定了液体出口的第二端,以及容纳在所述开式第一端的柱塞;使所述输入管的第二端与所述注射器液缸的液体出口相连;通过驱动所述往复线性驱动装置,在所述注射器的液体出口产生负压力,以便从所述注射器中抽出液体。 The method according to claim 17, further comprising: providing a syringe as the reservoir, the syringe is a cylinder having an open first end and a second end defining a liquid outlet, and received in the open first end of the plunger; said input is connected to the second end of the tube to the liquid outlet of the syringe cylinder; by driving the reciprocating linear drive means, the liquid outlet of the syringe to generate negative pressure, so that removal of fluid from the syringe.
Description  translated from Chinese
定量注液泵及其方法 Quantitative injection pump and method

技术领域 FIELD

本发明涉及注液泵,更特别涉及一种定量注液泵,一种用于注液泵的给药组件及一种用于对患者进行血管内注射时输送规定量药液的方法。 The present invention relates to the injection pump, and more particularly to a quantitative injection pump, an injection pump assembly for dosing and transporting a chemical solution when a predetermined amount of patient A method for intravascular injection.

为了确保具有潜在危险性药物的准确用量,已存在制造更精密复杂泵送设备的趋势。 To ensure accurate amount of potentially dangerous drugs, to produce more sophisticated pumping apparatus trend exists. 虽然,目前在技术上已能够成功提高泵送精度,但是仍存在一些严重的缺陷。 Although it is technically possible to successfully improve the accuracy of pumping, but there are still some serious flaws. 更重要的是,许多这些泵均依赖于非常精密和复杂的驱动设备和泵压头结构,因此增加了泵的复杂性和成本。 More importantly, many of these pumps rely on highly precise and complicated driving device and the pump head structure, thereby increasing the complexity and cost of the pump. 例如,虽然已经花费了很大的努力来设计更精密的蠕动泵,这种泵依靠将一低成本Ⅳ管作为一次性泵腔,但是,力图增加精确性必然会大大导致泵结构的复杂化及成本的提高。 For example, although a great deal of effort has been spent to design more sophisticated peristaltic pump, the pump will depend on a cost-Ⅳ tube as a disposable pump chamber, however, trying to increase the accuracy of the pump will definitely lead to complex structures and increase costs. 利用一次性盒体作为泵压头的泵的生产者也会遇到要求降低制造成本,提高可靠性和采用精密盒体的问题。 Use disposable cartridge body as pump head pump producers will encounter required to reduce manufacturing costs, improve reliability, and the use of sophisticated cassette problems.

本发明的目的在于克服上述一个或多个问题。 Object of the present invention to overcome one or more of the problems described above.

本发明的第一个方面提供了一种管内给药组件,其包括:一轴向运动的往复式泵压头,该泵压头具有一泵压头入口和一泵压头出口。 A first aspect of the present invention provides the administration of a tube assembly comprising: an axially reciprocating pump head movement, the pump head having a pump head inlet and a pump head outlet. 一输入管具有安装在泵压头入口的第一端及和适于与一贮液器相连的第二端。 An input terminal and a first and a second end adapted to connected to a reservoir tube having an inlet mounted on the pump head. 一输出管具有与泵压头出口相连的第一端及一适于与一患者血管液态相连的第二端。 An output tube having a pump head outlet connected to a first end and a liquid adapted for connection with a patient's vascular second end. 往复式泵压头的泵压头入口和泵压头出口最好沿泵压头轴向设置。 Reciprocating pump head pump head inlet and the pump head outlet is preferably disposed axially along the pump head. 给药组件可包括一与输入管第二端相连的贮液器,同时贮液器包括一注射器。 Administration assembly may include a tube with an input connected to the second end of the reservoir, while the reservoir comprises a syringe. 在一最佳实施例中,轴向运动的往复式泵压头包括一可滑动容纳在液缸内的活塞,所述活塞在液缸内的排放位置和再装填位置之间移动,以使液流抽入泵压头入口,并从泵压头出口排出。 In a preferred embodiment, the axial movement of the reciprocating pump head comprises a piston slidably received in said fluid cylinder to move the piston in the cylinder between a discharge position and fluid refill position, so that the liquid flow drawn into the pump head inlet, and is discharged from the pump head outlet. 一控制阀与液缸液态相连,以当活塞从排放位置移动至再装填位置时,促使液流仅从泵压头入口进入液缸,且当活塞从再装填位置移动至排放位置时,促使液流仅从泵压头出口排出。 A control valve is connected with the liquid cylinder, to when the piston from the discharge position to the refill position, prompting the flow only from the pump head inlet into the cylinder, and when the piston is moved from the refill position to the discharge position, prompting liquid flow only from the pump head outlet. 一连杆装配在活塞上,用于在排放位置和再装填位置之间移动活塞,连杆与一线性往复驱动装置接合。 A connecting rod mounted on the piston, for communication between the discharge position and the refill position of the piston, connecting rod and a linear reciprocating drive means engagement.

本发明的第二方面提供了一种管内注液泵,其包括:一轴向运动的往复式泵压头,该泵压头具有一泵压头入口和一泵压头出口。 The second aspect of the invention provides a tube within the injection pump, comprising: an axially reciprocating pump head movement, the pump head having a pump head inlet and a pump head outlet. 一壳体包括一容纳泵压头的泵压头接收器。 A housing including a receiving pump head pump head receiver. 一贮液器通过一输入管与泵入口液态相连。 A reservoir through a feed pipe connected to the pump inlet liquid. 一输出管具有与泵压头出口液态相连的第一端及适于与一患者血管液态相连的第二端。 An outlet tube having a first end and a second end adapted for patients with blood vessels connected to the liquid and a pump head connected to the liquid outlet. 一在壳体内的线性往复驱动装置可控制地与泵压头相连,以驱动泵压头。 A linear reciprocating drive within the housing, the control means may be connected with the pump head to drive the pump head. 贮液器最好也设置在壳体内。 Reservoir is also preferably disposed within the housing. 在另一种最佳结构中,一控制器可控制地与往复线性驱动装置相连,用于控制泵压头的预定程序操作,而给出一理想的输出曲线。 In another preferred construction, a controller controllably connected to the linear reciprocal drive means, for controlling the pump head of a predetermined program operation, to give a desired output curve. 在另一最佳实施例中,轴向运动的往复式泵压头包括一可滑动容纳在液缸中的活塞,所述活塞可在液缸内的排放位置和再装填位置之间轴向运动,以将液体吸入泵压头入口并从泵压头出口排出液体。 In another preferred embodiment, the axial movement of the reciprocating pump head includes a cylinder slidably received in the piston, the piston is axially movable between a discharge position and the fluid refill position of the cylinder to the liquid drawn into the pump head inlet and outlet from the pump discharge liquid pressure head. 当活塞从排放位置移动至再装填位置时,一与液缸液态相连的控制阀使液流仅从泵压头入口进入液缸,且当活塞从再装填位置移动至排放位置时,使液流仅从泵压头出口排出。 When the piston moves from the discharged position to the refill position, a control valve connected with the cylinder so that the liquid flow only from the pump inlet into the cylinder head, and when the piston is moved from the refill position to the discharge position, so that the liquid flow Only from the pump head outlet. 一装配至活塞的连杆在排放位置和再装填位置之间移动活塞。 A piston rod assembly to between the discharge position and the refill position of the piston. 所述连杆与一线性往复驱动装置接合。 Said connecting rod and a linear reciprocating drive means engagement. 线性往复驱动装置最好包括一具有一旋转驱动轴的电动机及一可控制地与驱动轴和轴向运动的往复式泵压头相连的线性转换器的旋转机构,用以驱动泵压头。 Linear reciprocating drive means preferably comprises a rotating mechanism having a rotary drive shaft of the motor and the reciprocating linear converter pump head and the axial movement of the drive shaft and connected to a controllable manner, for driving the pump head. 线性转换器的旋转机构可包括一偏心固定于电动机驱动轴上的凸轮及一受偏压接触凸轮边缘的凸轮随动件。 Rotation mechanism linear converter may comprise a cam eccentrically fixed to the motor drive shaft and a cam edge of the cam is biased into contact with the movable member. 当凸轮转动时,与轴向运动的往复式泵压头相连的凸轮随动件作线性往复运动。 As the cam rotates, the cam and the axial movement of the reciprocating pump head connected to the follower member into a linear reciprocating motion. 一与电动机相连的编码器与控制器电耦合,以便能够精确监控泵的输出。 Encoder and a controller electrically coupled with the motor connected to be able to accurately monitor the output of the pump.

本发明的第三方面提供了一种对患者进行管内注射药液的方法,该方法包括设置一轴向运动的往复式泵压头,该泵压头具有一泵压头入口和一泵压头出口并设有输入管和输出管。 The third aspect of the invention provides a patient the drug solution injection tube, the method comprising setting an axially reciprocating pump head movement, the pump head having a pump head inlet and a pump head export and has inlet and outlet pipes. 输入管的第一端与泵压头入口液态相连,且输入管的第二端与一贮液器液态相连。 A first end of the inlet tube and a liquid inlet connected to the pump head, and a second end connected to a reservoir of liquid feed tube. 输出管的第一端与泵压头出口液态相连,且第二端与患者的血管液态相连。 A first end of the outlet tube and the pump head is connected to the liquid outlet, and a second end connected to the patient's blood vessel liquid. 往复线性驱动装置与泵压头可控制地相连且被操纵使液体从贮液器排放至患者血管,在该方法的一个最佳实施例中,轴向运动的往复式泵压头为包括一雾化器的鼻腔定量喷雾泵机构,且该方法还包括阻塞所述雾化器。 Linear drive means and the reciprocating pump head can be manipulated and controllably connected to the liquid discharge from the reservoir to a patient blood vessel, in a preferred embodiment of the method, the axial movement of the reciprocating pump head to include a mist quantification of the nasal spray pump mechanism, and the method further comprises blocking the atomizer.

本发明的管内给药组件使用了一重量大大减轻的轴向运动的往复式泵压头,该泵压头多年来已在千万个手动往复式鼻腔定量喷雾泵中用于对患者鼻腔供给悬浮微粒药物。 Administration of the inner tube assembly of the present invention uses a reciprocating pump head greatly reduce the weight of the axial movement of the pump head has been used for many years in thousands of manual reciprocating nasal metered nasal pump supplying the suspension to the patient drug particles. 结果,可购得的泵压头成品数量实际上是极大的,因此可大大降低了成本。 As a result, the number of finished products available pressure head of the pump is actually enormous, thus greatly reducing costs. 另外,在大量场合下,简单的泵压头机构已能保证其精度和可靠性。 In addition, in a large number of situations, a simple pump head mechanism has been able to ensure its accuracy and reliability. 由于成本较低,因此给药组件易于采用一次性产品,从而进一步加强了卫生和安全性。 Due to lower costs, ease of administration, the use of disposable products, components, thus further strengthening the health and safety. 泵压头所具有的极轻重量有助其与流动性注液泵一起使用。 Extremely light weight pump head has helped to use it with liquidity injection pump. 因为泵压头需要简单的线性动作来产生精确的输出,因此,大量线性往复式驱动装置适于与装有轴向运动的往复式泵压头的注液泵一起使用。 Because the pump head requires simple linear movements to produce accurate output, therefore, a large number of linear reciprocating driving means is adapted with the axial movement of the injection pump is equipped with a reciprocating pump head together. 使用了所述泵压头的注液泵能够提供大致连续的液体流或快速注射。 Use of the pump head of the injection pump capable of providing a substantially continuous flow of liquid or bolus injection. 并且,它还能够在整个大量的泵压头动作期间输送非常准确的流体量。 Further, it is capable of delivering very precise amount of fluid throughout a large number of pressure head during pump operation.

图1为用于说明本发明管内注液泵的示意图;图2为利用了一注射贮液器的本发明管内注液泵的一个实施例的透视图;图3为图2中管内注液泵的泵送机构和给药组件的透视图;图4为用于本发明的管内注液泵的典型轴向往复泵头的分解视图。 Figure 1 is a schematic diagram of the present invention is an explanatory injection pump tube; Figure 2 is a perspective view of the use of an accumulator injection pipe of the present invention, an injection pump embodiment; injection pump inner tube 2 in Figure 3 is perspective view of the pumping mechanism and administering assembly; Figure 4 is a typical axially reciprocating pump head used in the present invention, the inner tube of the injection pump of an exploded view.

给药组件14包括一泵压头16,该泵压头通过一输入管20、由一贮液器18接收液体且经一输出管22将液体输送至与患者血管液态相连的一患者连接体24。 Dosing assembly 14 includes a pump head 16, the pump head 20 through an inlet tube, by a reservoir 18 receives liquid through an outlet tube 22 and the liquid delivered to a patient and the patient is connected to the liquid vessel linker 24 . 患者连接体可以是本领域已知的针,导管或任意其它适合的装置。 Patients linker may be known in the art needles, catheters or any other suitable means. 一排气过滤器26最好与输出管液态相连,以便在将液体导入至患者之前,排出任意可能已导入液体内的气泡。 An exhaust filter 26 is preferably connected to the output tube of liquid so that the liquid is introduced into the patient prior to discharge any air bubbles may have been introduced into the liquid inside. 泵压头16最好包括一轴向运动的往复式泵压头,其带有一与输入管20液态相连的泵压头入口28和一与输出管22液态相连的泵压头出口30。 The pump head 16 preferably includes an axial reciprocating movement of the pump head, which is provided with a pump head with inlet conduit 20 connected to the liquid inlet 28 and an outlet tube 22 and a liquid outlet connected to the pump head 30. 如图1所示,泵压头入口28和出口30最好是同轴的。 As shown in Figure 1, the pump head inlet 28 and outlet 30 are preferably coaxial. 泵压头16最好包括一成品鼻腔定量喷雾泵机构,该机构已被改进来减活任何雾化器,以便空气不会经定量喷雾泵进入被泵送的液体。 The pump head 16 preferably includes a quantitative finished nasal spray pump mechanism that has been modified to deactivating any atomizer so that air does not enter the liquid being pumped by the quantitative spray pump. 在Haber等人的美国专利NO.5,433,191中披露了这种鼻腔定量喷雾泵,整个文献可在本申请中结合使用。 Such quantitative discloses nasal spray pump in Haber et al., U.S. Patent NO.5,433,191 using the entire document may be incorporated in the present application. 合适的鼻腔定量喷雾泵机构的其它例子包括德国Pfeiffer制造的装置,其包括型号no.10358BSK 5635(100μl)及型号no.6958.59002/600(50μl)。 Other examples of suitable nasal spray pump mechanism comprises a quantitative means Pfeiffer manufactured in Germany, which includes model no.10358BSK 5635 (100μl) and model no.6958.59002 / 600 (50μl). 这些典型泵压头中的每一个均具有同轴的泵入口和出口,且被轴向往复驱动。 Typical pump head each have coaxial pump inlet and outlet, and is axially reciprocally driven.

泵体12包括一用于封装泵中电子部件及驱动装置的壳体36。 Pump 12 includes a pump for encapsulating the electronic component and the drive unit housing 36. 在壳体中设置一用于控制泵驱动装置工作的控制器38。 Disposed in the housing for controlling the pump drive a working controller 38. 控制器38最好包括具有选择功能的可编程微信息处理器和存储器,以便控制并监测泵送机构的工作且控制用于患者的药液的选择输送曲线。 The controller 38 preferably includes a programmable microcontroller, select an information processor and a memory, in order to control and monitoring and controlling a pumping mechanism for pumping the liquid to a patient's curve. 另外,如本领域技术人员所理解的那样,多种逻辑电路能够实现控制器的功能,不过与微信息处理器和配套的存储器一样,这些电路不具有重设程序的优点。 Additionally, as the skilled artisan will appreciate, a variety of logic circuits to achieve functions of the controller, but with the micro processor and associated memory information, these circuits do not have the advantage of resetting procedure.

控制器38通过连接器40被连接至包括一编码器44的驱动装置42,编码器44本身通过连接器46连接至控制器。 The controller 38 through the connector 40 is connected to the driving device 44 comprises an encoder 42, encoder 44 is itself connected to the controller via connector 46. 驱动装置可采用任意用于对泵压头16提供线性往复驱动的适合驱动装置。 Drive means may take any of the pump head 16 is used to provide a linear reciprocating driving means for driving. 编码器44的功能在于对控制器38提供一表示驱动周期的信号,因此泵压头起动来监控泵的输出。 Encoder 44 function is to provide a signal to the controller 38 a view illustrating an operation cycle, and therefore pump head start to monitor the output of the pump. 驱动装置42最好为一电动机且编码器为一霍尔传感器。 Driving means 42 is preferably an electric motor and that the encoder is a Hall sensor. 在这一实施例中,电动机的驱动轴48与线性转换器50的转动机构相耦合,线性转换器50本身通过联动装置52可控制地与轴向运动的往复泵压头16相连,联动装置52可采用凸轮从动件或类似装置。 In this embodiment, the drive shaft of the motor 48 and linear transducer is coupled to the rotation mechanism 50, 16 is connected to the linear converter 50 itself can be controlled by the linkage 52 to a reciprocating pump with axial movement of the ram, the linkage means 52 the cam follower may be used or the like. 另外,驱动装置42可以是能够直接对泵压头16施加线性往复运动的电动螺线管或气动缸。 Electric addition, the driving device 42 may be able to be applied directly to the pump head 16 linear reciprocating solenoid or pneumatic cylinder. 泵体12最好也包括一接收器53,其用于容纳泵压头16和给药组件14的其它部件并保持给药组件14与下文所述的泵驱动设备和传感器可控制地相连。 The pump body 12 also preferably includes a receiver 53, for receiving the pump head 16 and the dosing member 14 and other components remain attached to controllably administered assembly 14 described below with the pump drive devices and sensors.

泵体12还包括多个传感器。 Pump body 12 further includes a plurality of sensors. 一位置传感器54通过连接器56与所述控制器相连,其用于对所述控制器发出说明泵压头16在接收器53内正确定位的信号。 A position sensor 54 through the connector 56 connected to said controller for said controller to issue instructions to the pump head 16 in the correct positioning of the receiver 53 a signal. 按程序设定所述控制器,以便如果未接收到信号,则会对使用者提供一适当的告警信号。 According to the procedure sets the controller, so that if the signal is not received, it will provide an appropriate alert signal to the user.

一出口压力传感器58通过连接器60与所述控制器相连。 An outlet pressure sensor 58 is connected through connector 60 to the controller. 所述出口压力传感器可控制地与给药组件14的输出管22相连,用于检测在输出管22内部、表示下游堵塞的压力增量。 The outlet pressure sensor assembly can be controlled with the administration tube 22 is connected to the output 14, for detecting the internal pressure increment output tube 22, represents a downstream blockage. 一入口压力传感器162通过连接器64被连接至所述控制器且可控制地与输入管20相连,以便探测在输入管20中表示缺少泵压头16上游流体的压力减少量,其可能在贮液器18排空时产生。 An inlet pressure sensor 162 through the connector 64 is connected to the controller and connected to the input tube 20 may be controlled so as to detect 20 indicates lack of pressure in the inlet tube 16 upstream of the pump head to reduce the amount of fluid, which may in the reservoir generated when the accumulator (18) emptying. 控制器38通过连接器66被连接至电源68。 The controller 38 through the connector 66 is connected to the power supply 68. 电源68可以采用电池或一包括合适交/直流转换器的标准交流输出端的接线。 Power supply 68 can include a battery or an AC output terminal of the appropriate standard AC / DC converter. 设置与电源相连的另一传感器来探测电源状态。 Set the power supply is connected to another sensor to detect the power status. 所有传感器均经它们各自的连线将信号提供至控制器38。 All sensors were confirmed by their respective connection provides a signal to the controller 38. 正确设定控制器38的程序以接收并处理其接收的传感器信号。 Correct setting program of the controller 38 to receive and process the sensor signals it receives. 正确的影像或告警信号通过以连线72连接至所述控制器的显示器70被输送至使用者。 The right image or the alarm is passed to the wire 72 is connected to the display controller 70 is delivered to the user. 除了显示告警信号以外,所述显示器还将有用信息,如泵的速率,泵送量,输送曲线等输送至泵的使用者。 In addition to the alarm signal is displayed, the display will also be useful information, such as pump rate, volume pumped, delivery profile delivered to the pump and other users. 所述显示器可采用传统的液晶点阵显示器。 The display may be a conventional liquid crystal dot matrix display. 用户输入端74通过连线76与所述控制器耦合。 User input terminal 74 via line 76 is coupled with the controller. 使用者通过所述输入端控制泵的操作。 User-controlled operation of the pump via the input terminal. 控制器38响应各种输入信号,从而控制泵送机构。 The controller 38 in response to various input signals, thereby controlling the pumping mechanism.

注液泵10可以被设计为一次性的,同时给药组件14被永久密封在壳体36内部。 Injection pump 10 may be designed to be disposable, while administration of assembly 14 is permanently sealed inside the housing 36. 显然,这一实施例无需使用位置传感器54。 Obviously, this embodiment eliminates the need for the position sensor 54. 另一方面,泵体是可以重复使用的,而给药组件14则是一次性的。 On the other hand, the pump body is reusable, while the administration assembly 14 is disposable.

本发明中管内注液泵的注射器泵80的例子如图2所示。 Examples of the present invention, the tube of the syringe pump injection pump 80 is shown in Fig. 注射器泵80具有一刚性壳体82,该壳体包括有一封闭泵机械部分和电子部分的外壳84。 The syringe pump 80 has a rigid housing 82, the housing comprises a closed pump housing 84 and the mechanical portion of the electronic part. 在外壳84的盖90中设有一如传统液晶点阵显示器这样的显示器86及多个输入端88。 In the housing cover 90 is provided with a conventional LCD dot matrix display such as a display 86 and a plurality of input terminals 88 84. 所述壳体还限定了一用于容纳给药组件14的细长形接收器92。 Said housing further defining an elongated receiver 14 for receiving the administration assembly 92. 在这一实施例中,给药组件14包括一通过输入管96连接至一实际往复式泵压头98的注射器94及一被连接至泵压头98中泵压头出口的输出管100。 In this embodiment, the dosing assembly 14 comprises a tube 96 is connected via an input to an actual reciprocating pump head 98 and a syringe 94 is connected to the pump head 98, the output of the pump head outlet pipe 100.

注射器94可采用本领域熟知的传统结构。 Syringe 94 may be a conventional structure known in the art. 注射器94还包括一液缸102,其具有一用于容纳柱塞106的开式远端104。 Syringe 94 further comprises a hydraulic cylinder 102 having a plunger 106 for receiving the open distal end 104. 液缸102的近端限定了用于液缸102中所含的液体的出口108。 The proximal end of cylinder 102 is a liquid outlet defining a liquid contained in the cylinder 102 for 108. 如本领域技术人员易于理解的那样,通过抽出柱塞106可将液体经出口108吸入所述液缸,或通过插入活塞可排出所述液体。 As those skilled in the art will readily appreciate, by withdrawing the plunger 106 may be drawn into the liquid through the outlet cylinder 108, or by inserting the piston can be discharged liquid.

图3更详细地示出了注射器下游的给药组件14以及泵机构。 Figure 3 shows in more detail a dosing syringe assembly 14 and downstream of the pump mechanism. 轴向往复式泵压头98包括同轴设置的泵压头入口110和泵压头出口112,输入管96被连接至泵压头入口110,输出管100被连接至泵压头出口112。 Axially reciprocating pump head 98 includes a coaxial pump head inlet disposed 110 and pump head outlet 112, inlet tube 96 is connected to the pump head inlet 110, outlet tube 100 is connected to the pump head outlet 112. 在图3的分解图中所示的轴向往复式泵压头98包括一限定了泵腔和一活塞116(参见图3)的液缸114,所述活塞在液缸114内的最小泵腔容积量的排放位置和最大泵容积量的再装填位置之间往复滑动。 Axially reciprocating pump head shown in exploded view in FIG. 3 includes a 98 defining a pump chamber and a piston 116 (see FIG. 3) of the hydraulic cylinder 114, the minimum piston pump chamber 114 in the cylinder reciprocal sliding between the discharge position and the maximum volumetric capacity of the pump volumetric capacity refill position. 活塞116由连杆118驱动,连杆118还限定了泵压头的出口112。 Piston 116 driven by a connecting rod 118, the link 118 also defines the outlet 112 of the pump head. 所述连杆还包括一推压盘120,如下文更详细说明的那样,用于促进连杆的动作。 The link further comprises a pressing plate 120, as described in greater detail below, the operation for promoting the link. 如图4所示,推压盘120为与连杆118分离的独立元件。 As shown, the pressing plate 4 and the connecting rod 120 to 118 independent separate elements.

所述给药组件通过一固定块126与泵的驱动装置可控制地相连。 The dosing assembly by a fixed block 126 is connected to the pump drive means for controllably. 固定块126限定了一支架128,其用于容纳轴向往复式泵压头98的液缸114。 Fixed block 126 defines a bracket 128, for accommodating axial reciprocating pump head 98 of the hydraulic cylinder 114. 在限定于固定块126中的槽130内设有一推动捕捉板适配器(pushcapture plate adapter)124。 In limited to fixed block 126 in tank 130 equipped with a push to capture the plate adapter (pushcapture plate adapter) 124. 一凸轮随动件132卡设在固定块126的凹口134内部,且可沿箭头136所示方向、由一偏心置于电动机142的轴140的凸轮138往复线性驱动。 A cam follower 132 provided in the card 134 inside the recess 126 of the fixed block and movable in the direction indicated by arrow 136, by an eccentric cam 138 into the linear motor 142 reciprocates the shaft 140 of the drive. 从图3中可明显得知,当轴140转动时,通过凸轮随动件与凸轮138边缘啮合,凸轮随动件132沿轴向运动的泵压头98轴线作线性往复运动。 As is apparent from Figure 3 that, when the shaft 140 rotates, cam follower by engagement with the edge of the cam 138, the cam follower 132 to move axially of the axis of the pump head 98 is linearly reciprocated. 可利用一未示出的弹簧偏压凸轮随动件与一凸轮接触。 Can be used a not shown spring biased cam follower in contact with a cam. 凸轮随动件132的远端限定一个槽144,其容纳了给药组件的连杆118并反作用于推压盘120以轴向驱动泵压头98。 The distal end of the cam follower 132 defines a slot 144 that accommodates the connecting rod 118 and the administration component reacts to the pressing plate 120 to an axial drive pump head 98.

输出管100最好是一标准静脉注射(Ⅳ)管,该管通常采用聚氯乙烯(PVC)。 Output tube 100 is preferably a standard intravenous (Ⅳ) tube, which is usually polyvinyl chloride (PVC). 输出管100可包括一硅酮部分122,其通过捕捉板/适配器124连接至输出管100的主体。 Outlet tube 100 may include a silicone section 122 which is connected to the body through the outlet tube 100 to capture the plate / adapter 124. PVC Ⅳ管(或硅酮部分122)安装在一起到上述图1所示的出口压力传感器58作用的压力检测电阻144之间。 Between the PVC Ⅳ tube (or the silicone section 122) mounted together to said outlet pressure sensor 58 in Fig. 1 shows the effect of the pressure sensing resistor 144. 压力检测电阻探测与由下游阻塞造成的压力增量相关的管膨胀,并在超过选定压力时,对控制器发出信号。 Pressure sensing resistor probe tube expansion and pressure increase caused by the downstream blockage related and, when the pressure exceeds a selected, the controller sends a signal.

图3为一典型的轴向运动的往复式泵压头98。 Figure 3 is a typical reciprocating pump axial movement of the ram 98. 泵压头98包括一内部设有活塞116的液缸114。 The pump head 98 comprises an inner cylinder provided with a piston 116 114. 特别是,球体146容纳在液缸114中且抵靠在液缸114中直径减小的部分148。 In particular, the ball 146 received in the cylinder 114 and abuts against the cylinder 114 of reduced diameter portion 148. 随后,将弹簧150设置在液缸内,且抵靠在液缸内、邻接直径减小部分148的凸缘(未示出)。 Subsequently, the spring 150 disposed in the liquid cylinder, and abuts against the fluid cylinder, adjacent to the reduced diameter of the flange portion 148 (not shown). 接着,杆152沿轴向被插入液缸内且衔接弹簧150的远端。 Subsequently, the rod 152 is axially inserted into the liquid cylinder and the convergence of the distal end of the spring 150. 与连杆118一样,活塞116设置在弹簧150上。 And connecting rod 118, the piston 116 is provided on the spring 150. 连杆118内的小孔154限定了将液体输送至泵压头出口112的导管,盖156与液体114上的凸缘158接合,以使轴向往复运动的泵压头98上的各部件保持在它们的装配位置。 Apertures 154 of the link 118 defines the liquid delivered to the pump head outlet conduit 112, the cover 156 and the flange 158 engages the liquid 114, so that the axially reciprocating pump head 98 on each member holding in their assembled position. 推压盘120在端接泵压头出口118的孔159中容纳了连杆118的远端。 Terminating the pressing plate 120 in the pump head 159 in the outlet aperture 118 to accommodate the distal end of the connecting rod 118. 借助推压盘120轴向将连杆118压入使活塞116运动至排放位置,泵压头经液缸泵送液体。 120 by means of the pressing plate 118 pressed into the axial direction to the piston rod 116 is moved to the discharge position, the pump head through the cylinder of the pumped liquid. 通过减小连杆118上的轴向力,弹簧150偏压活塞116至再装填位置。 By reducing the axial force rod 118, the spring 150 bias the piston 116 to a refill position. 当迫使活塞从排放位置朝装填位置运动时,球体146在直径缩小部分148处封闭了泵出口110。 When forcing the piston toward the loading position from the discharge position, the ball 146 in reduced diameter section 148 of the pump outlet 110 closed. 因此,在液缸内的液体由泵出口排出。 Therefore, the liquid discharged from the cylinder of liquid in the pump outlet. 当弹簧偏压活塞至装填位置时,球体146上的封闭压力减弱且流体流入泵入口110。 When the spring biasing the piston in the loaded position, the closure pressure on the ball 146 is weakened and the fluid flows into the pump inlet 110. 通过一单向止回阀(未示出)可防止液体流入连杆118的泵出口112。 Through a one-way check valve (not shown) prevents the liquid to flow into the pump outlet 118 of the link 112.

泵压头排出行程可为具有一系列步进部分的全排放行程,以提供较小量的快速给药(bolus dosage)或可采用具有快速返回功能的连续全排放行程以提供大致连续的液体流。 The pump head discharge stroke can be a series of step with full discharge stroke portion, to provide a small amount of a rapid administration (bolus dosage) or may be used with a fast return of continuous full discharge stroke to provide substantially continuous liquid flow . 如本领域技术人员所理解的那样,可将凸轮形状设计为能允许泵压头机构中的弹簧大体瞬时将泵柱塞从排放位置移至再装填位置,从而开始泵送行程的另一排放部分。 As the skilled artisan will appreciate, the shape of the cam can be designed to allow the pump head spring mechanism substantially instantaneously move the pump plunger from the discharged position refill position, to start another discharge portion of the pumping stroke .

虽然未示出,可采用一标准Ⅳ袋代替注射器94。 Although not shown, may be used in place of a standard syringe 94 Ⅳ bag. 显然,这要求对刚性外壳82进行改进。 Obviously, this requires a rigid housing 82 be improved. 另一方面,液体的供给源可远离泵的外壳,并经与一远程贮液器相连的输入管96供给至给药组件14。 On the other hand, the supply source of the liquid may be remote from the pump housing, and dried with a remote reservoir connected to the inlet tube 96 is supplied to the dosing assembly 14.

本发明的注液泵和给药组件使用了一种标准化泵压头,通过大量用作鼻腔定量,这种泵压头泵压头已证明是精确且非常可靠的。 And administration of the injection pump assembly of the present invention uses a standardized pump head, is used by a large number of nasal quantitative, this pump head pump head has proved to be accurate and very reliable. 结果,在不有损于精确性或可靠性的情况下,使给药组件的成本降至最低。 As a result, without detriment of the accuracy or reliability of the case, the cost of administration of the component to a minimum. 泵压头的简单线性动作可通过多种不同形式的往复线性驱动装置,包括非常简单、价廉且高可靠性的机构控制。 Pump head by a simple linear motion in many different forms of reciprocating linear drives including very simple, inexpensive and highly reliable mechanism control. 给药组件可采用一种泵组件,其包括一能够以不同输送曲线进行注射的预定程序微信息处理器。 A pump assembly may be administered assembly, comprising a conveyor capable of different injection curve information predetermined program micro processor.

Referenced by
Citing PatentFiling datePublication dateApplicantTitle
CN104033348A *9 Jun 201410 Sep 2014四川大学Digital quantitative continuous liquid injection pump
Classifications
International ClassificationA61M5/142, F04B13/00, F04B1/34, A61M1/00, F04B9/02, F04B1/00, F04B23/00
Cooperative ClassificationA61M5/142
European ClassificationA61M5/142
Legal Events
DateCodeEventDescription
16 May 2001C06Publication
23 Oct 2002C02Deemed withdrawal of patent application after publication (patent law 2001)