CN102670815B

CN102670815B - External traditional Chinese medicine for curing beriberi

Info

Publication number: CN102670815B
Application number: CN2011100592725A
Authority: CN
Inventors: 王力
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-03-14
Filing date: 2011-03-14
Publication date: 2013-08-07
Anticipated expiration: 2031-03-14
Also published as: CN102670815A

Abstract

The invention relates to an external traditional Chinese medicine for curing beriberi and belongs to the technical field of traditional Chinese medicines. The pharmacodynamic raw materials of the external traditional Chinese medicine include, by weight, 10%-20% of fructus evodiae stirred and baked with ginger juice, 10%-20% of phellodendron processed with salt-water, 10%-20% of sophora flavescens, 8%-18% of fresh cordate houttuynia, 8%-15% of cutch, 8%-15% of nutgall, 3%-8% of toad venom powder and 5%-12% of peppermint oil. The medicine has special prominent curing effect for various beriberi, and beriberi patients cannot suffer a relapse of the beriberi and rebounding of the beriberi. The medicine has functions such as pain relief, itch relief, blood stanching, pus relief, festering relief, necrotic tissue removal, fresh tissue generation, bacterium prevention, antivirus and tissue regeneration prompting. The medicine has the advantages of being simple in processing, convenient to use, easy to carry along, low in cost, unique in effect, suitable for industrial processing and production and the like.

Description

A kind of external Chinese medicine for the treatment of beriberi

Technical field

The present invention relates to the field of Chinese medicines, particularly relate to a kind of with the formulated external specific drug that is specifically designed to the treatment beriberi of Chinese medicine compound.

Background technology

Beriberi is the most common a kind of disease of China resident, the urban residents that particularly are engaged in agriculture for a long time, build, raise and the colony that is poorly off, the easy infection beriberi of these people.

For a long time, for beriberi special good therapeutic scheme and special effect medicine never, cause many patients' beriberi protracted course of disease, outbreak repeatedly in the medical treatment, have in addition also caused other disease.Because the cause of disease of beriberi is complicated, various antibacterials, virus is mixed and is existed, and interacts, and is difficult to effectively suit the medicine to the illness radical cure.

According to investigations, be engaged in the labourer in raising, building, farmland for a long time, wherein suffer from the crowd of beriberi up to about 10%.Suffer from after the beriberi, most of people take exception to, and not medication is not treated yet, and cause finally that sb.'s illness took a turn for the worse, are difficult to cure.Though various about the medicine number for the treatment of beriberi in the market, really there is the medicine of special positive effect not have real the genus, thus cause the beriberi patient to the distrust for the treatment of and medicine, thereby abandoned treatment and medication.But they very thirst for that a kind of medicine that really can effectively treat beriberi is arranged, and can really remove the misery of disease for them, for their life and health brings glad tidings.

Summary of the invention

The present invention is directed to the defective in the above-mentioned field, the inventor uses Chinese medical theory through repeatedly practising for many years, repeatedly adjusts drug formulation and concocting method, has invented the pure Chinese medicine external specific drug of this group special for treating beriberi.This medical instrument has pain relieving, antipruritic, hemostasis, ends pus, only festers, removes the rotten and lets fresh grow, antibiotic, antiviral, and effects such as short tissue regeneration all have outstanding especially therapeutic effect to various beriberi, do not recur, rebound.

A kind of external Chinese medicine for the treatment of beriberi, its active ingredient is made up of following crude drug and weight percentage thereof: processed with Rhizoma Zingiberis Recens Fructus Evodiae 10-20%, processed with salt Cortex Phellodendri 10-20%, Radix Sophorae Flavescentis 10-20%, fresh Herba Houttuyniae 8-18%, Catechu 8-15%, Galla Chinensis 8-15%, Venenum Bufonis powder 3-8%, Oleum menthae 5-12%.

Preferably: processed with Rhizoma Zingiberis Recens Fructus Evodiae 10-18%, processed with salt Cortex Phellodendri 13-20%, Radix Sophorae Flavescentis 12-20%, fresh Herba Houttuyniae 10-15%, Catechu 10-15%, Galla Chinensis 10-12%, Venenum Bufonis powder 5-7%, Oleum menthae 7-10%.

More preferably: processed with Rhizoma Zingiberis Recens Fructus Evodiae 16%, processed with salt Cortex Phellodendri 16%, Radix Sophorae Flavescentis 15%, fresh Herba Houttuyniae 15%, Catechu 12%, Galla Chinensis 12%, Venenum Bufonis powder 5%, Herba Menthae 9%.

Described external Chinese medicine is unguentum.

Above-mentioned external preparation method of Chinese medicine, (1) weighting raw materials by weight, (2) produce the aqueous extract of processed with Rhizoma Zingiberis Recens Fructus Evodiae, processed with salt Cortex Phellodendri, Radix Sophorae Flavescentis, (3) water vapour steaming and decocting behind the mixing in the aqueous extract that Catechu and Galla Chinensis are pulverized, fresh Herba Houttuyniae is mashed adding (2) is become paste, (4) dry in the air cold to 30-25 ℃ of adding Venenum Bufonis powder and Oleum menthae, stirring gets final product.

Crude drug in the described step (2) is crushed to powder, is conducive to quick, the effectively extraction of effective ingredient.

Described step (3) digestion time is 3 hours.

This prescription is made up of following eight flavor Chinese medicines: Fructus Evodiae, Cortex Phellodendri, Radix Sophorae Flavescentis, Herba Houttuyniae, Catechu, Galla Chinensis, Venenum Bufonis, Herba Menthae.The most outstanding characteristics of we are with the multi-flavor medicine in the side, and through special preparation method, make medicine reach combination among the strong ones, by multipath, many target spots, realized expelling pathogenetic factors and reinforcing antipathogenetic qi, equilibrium between yin and yang, improvement adjust the affected area environment, gives full play to the sterilization detoxifcation of medicine, the function of removing the rotten and letting fresh grow, the real etiology and pathogenesis of eliminating exists and development environment condition, and beriberi is cured in the shortest time completely.

1, Fructus Evodiae: be rutaceae Fructus Evodiae green fruit

Another name: Fructus Evodiae, the Podbielniak Fructus Evodiae, the Guizhou Fructus Evodiae, Fructus Zanthoxyli Ailanthoidis, smelly spicy tree is dredged the hair Fructus Evodiae, A, the lacquer spicy, the floating and thready pulse Fructus Evodiae, the gas spicy, bent medicine, excellent spicy, Shi Hu, tea is peppery, Fructus Zanthoxyli Ailanthoidis

Composition: contain organic compound such as volatile oil, rutaecarpin, bitter principle, steroidal

Nature and flavor: arduous, warm, poisonous.

Effect: warming middle-JIAO, pain relieving is regulated the flow of vital energy, dampness, the contrary acid regurgitation of stopping vomiting, headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, abdominal pain during menstruation is had loose bowels just before dawn, vascular hypertension, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.

Annotate: when this medicine was used for we, unavailable salt, vinegar, Radix Glycyrrhizae processed product must adopt the processed with Rhizoma Zingiberis Recens Fructus Evodiae, can produce distinctive therapeutic effect.Processed with Rhizoma Zingiberis Recens: get clean Fructus Evodiae, add Rhizoma Zingiberis Recens juice and mix thoroughly, fry and do to spending.Every Fructus Evodiae 100kg is with Rhizoma Zingiberis Recens 25kg extracting juice.

2, Cortex Phellodendri: be the skin of rutaceae Cortex Phellodendri

Composition: contain organic compound such as berberine, phellodendrine, keto acid, sterol

Nature and flavor: bitter cold

Effect: heat and toxic materials clearing away medicine; Heat clearing and dampness removing medicine.Cure mainly: hygropyretic dysentery, have loose bowels, jaundice; Nocturnal emission, stranguria with turbid discharge, leukorrhagia; The hectic fever due to YIN-deficiency consumptive fever; And aphtha of the mouth and tongue; Conjunctival congestion and swelling pain; Skin sore; Skin eczema.

Annotate: our unavailable wine, honey product, palpus be used the processed with salt Cortex Phellodendri.Stir-baked CORTEX PHELLODENDRI with salt solution: get the Cortex Phellodendri sheet, spray with saline, mix thoroughly, put in the pot with the little stir-fry of slow fire, taking-up cools, and dries (every Cortex Phellodendri sheet 100 jin with 2 jin half of Sal, add certain amount of boiling water and dissolve clarification).

3, Radix Sophorae Flavescentis: be the root of subfamily plant Radix Sophorae Flavescentis

Composition: contain organic compound such as multiple alkaloid, flavonoid, kaempferol.

Nature and flavor: bitter cold.

Effect: heat clearing and damp drying; Wind dispelling insecticide.Main damp-heat dysentery; Discharging fresh blood stool; Jaundice; Dysuria; Edema; Leukorrhagia; Pudendal pruritus; Scabies; Leprosy; Skin pruritus; The noxious dampness skin infection. the Deficiency and coldness of spleen and stomach person avoids clothes.The careful usefulness of stomach weak person.

4, Herba Houttuyniae: be the saururaceae plant houttuynia cordata whole herb with root

Composition: herb contains volatile oil, contains very strong antimicrobial component Herba Houttuyniae comet in the oil.

Nature and flavor: hot cold

Effect: heat-clearing and toxic substances removing, inducing diuresis to remove edema.Control pneumonia, lung abscess, hematodiarrhoea, malaria, edema, gonorrhea, leucorrhea, carbuncle, hemorrhoid, proctoptosis, eczema, tinea alba, scabies.

5, Catechu: be the concentrate of subfamily plant catechu myron liquid

Composition: contain the gentle matter of catechu grass, cachou extract, wait organic compound

Nature and flavor: pained flat

Effect: removing dampness is arranged, granulation promoting, hold back skin ulcer, hemostasis, effect such as fester only.

6, Galla Chinensis: post the insect gall that stays on the Fructus rhois chinensis tree for times Aphidiadae insecticide Chinese Nut-gall aphid

Another name: Wu Yanpao, Conch Meretricis seu Cyclinae, hundred worm storehouses, red autumnal leaves peach, non-irrigated gall nut, Chinese Nut-gall aphid, melaphis peitan Tsai et Tang, lacquer gall nut, wooden Radix Aconiti Lateralis Preparata, Balls on the Folium rhois chinensis

Composition: contain tannin, organic compound such as tannic acid, resin

Nature and flavor: sour, puckery, cold.Return lung, large intestine, kidney channel.

Effect: the pathogenic fire reducing of astringing the lung, relieving diarrhea with astringents, the arresting sweating hemostasis, removing dampness is held back skin ulcer.Be used for chronic cough of deficiency lung, the lung-heat phlegmatic cough, the chronic diarrhea chronic dysentery, night sweat is quenched one's thirst, the hemorrhoidal bleeding of having blood in stool, traumatic hemorrhage, carbuncle sore tumefacting virus, Skin wet and rotten.

7, Venenum Bufonis: this product is the dry secretions of Bufonidae animal Bufo siccus Bufo bufo gargarizans Cantor or Bufo melanostictus B.melanostictus Schneider.

Different name: Oviductus Ranae shortcake, Oviductus Ranae slurry, toad shortcake

Nature and flavor: suffering, temperature; Poisonous.The GUIXIN warp.

Effect: detoxifcation, pain relieving, the refreshment of having one's ideas straightened out.Be used for the carbuncle furuncle, laryngopharynx swelling and pain, the heatstroke coma, stomachache is vomited and diarrhoea.

The present invention is with in the direct adding side behind its grind up.

8, Oleum menthae: for the bright stem and leaf of Herba Menthae distills the aromatic oil that makes

Composition: contain Organic substances such as menthol, ketone, rosmarinic acid

Nature and flavor: Herba Menthae acrid in the mouth, cool in nature is nontoxic.

Effect: wind and heat dispersing, detoxifcation, pain relieving, antipruritic, go effects such as skin heat.

We are compound preparation, and prescription designs at first based on the thorough elimination cause of disease.Processed with Rhizoma Zingiberis Recens Fructus Evodiae in the side, processed with salt Cortex Phellodendri, Radix Sophorae Flavescentis itself all have the effect of stronger antibacterial, antiinflammatory, antiviral, treatment beriberi.This three flavors Chinese medicine has more highlighted extremely strong sterilization, antiviral, dampness again through the process of preparing Chinese medicine and the adjustment of specific process, and functions such as pain relieving have special role to eliminating the cause of disease.The bright product of Herba Houttuyniae for suppress multiple pathogenic bacteria, virus has very strong effect, is potent heat-clearing and toxic substances removing, the pain that disappears evacuation of pus improves the best medicine of exempting from the disease cell function, can strengthen ourly sterilize, antiviral, elimination etiology and pathogenesis advantage.Catechu in the side, Galla Chinensis mainly act as removing dampness, hold back the open sore part, hemostasis, end pus, only fester, aforementioned a few flavor medicine produces joint effect with it, remove the focus environment, this two flavors medicine all has effect such as removing the necrotic tissue and promoting granulation and pain relieving preferably, therefore provides the good condition of removing the rotten and letting fresh grow for the focus rehabilitation.So the cause of disease of elimination pro-is arranged, the environment that must change follow-up could be established newborn may existing again, for new organization is created essential condition.Venenum Bufonis mainly act as pain relieving and produces anaesthetic effect.Because of severe patient pain unbearably, this medicine also has certain zest, add the Venenum Bufonis composition after, make the patient can alleviate the pain sensation.Oleum menthae, main the heat effect that disappears, beriberi belongs to pyretic toxicity disease, and Oleum menthae can produce cool and sweet-smelling sensation to the affected part.Through the reasonable compatibility of above-mentioned eight kinds of medicines, it is outstanding especially that its sterilization, antiviral, heat clearing and damp drying are ended pus, hemostasis, pain relieving, antipruritic effect, and through many person-times of application for many years, effect is fairly obvious.We's reason and good sense is: to eliminate etiology and pathogenesis, be auxilliary with the environment that changes the affected part, highlight polarity and the application of medicine.

Chinese medicine of the present invention is medicine for external use, can adopt various forms.As the solid in the above-mentioned raw materials medicine is pulverized, add the appropriate solvent paste making agent (this solvent generally adopts water) that stirs with the liquid material medicine then, smear the affected part: the solid material medicine can also be made water and mention thing and liquid material medicine and be mixed together and become liquid preparation, soak or smear the affected part; Or the above-mentioned raw materials medicine become packaged preparation, and solid material medicine and liquid material medicine are packed respectively, are soaked in water during use, and medicinal liquid soaks the affected part and all can simultaneously.

Using method and suitable disease

1, before smearing ointment, the sufferer place must be cleared up, clean, disinfect the back coating.

2, thickness of covering is 1 millimeter.

3, for more serious patient, available health cotton balls soaks full ointment behind the coating, and the absorbent cotton ball chuck to the toe seam, is being swathed toe with gauze, is conducive to bring into play drug effect.

4, this ointment is applicable to all kinds of beriberi, no matter slight, severe all has outstanding therapeutic effect.

5, for the not diabrosis state of an illness of toe epidermis, coating 1-3 days, all can be cured at every day 2-3 times.

6, lighter for toe skin and flesh ulceration, coating 3-5 days, all can be cured at every day 3-4 times.

7, fester for toe, the blood of suppurating, the slough severe patient of smelling as of rotten fish, coating 4-7 days, can all be cured in 7 days at every day 4-5 times.

The specific embodiment

The present invention is described in further detail below in conjunction with embodiment.

Following crude drug is commercially available.

Embodiment 1

Processed with Rhizoma Zingiberis Recens Fructus Evodiae 10Kg, processed with salt Cortex Phellodendri 20Kg, Radix Sophorae Flavescentis 20Kg, fresh Herba Houttuyniae 8Kg, Catechu 8Kg, Galla Chinensis 15Kg, Venenum Bufonis powder 7Kg, Herba Menthae 12Kg.

Preparation method is: processed with Rhizoma Zingiberis Recens Fructus Evodiae, processed with salt Cortex Phellodendri, Radix Sophorae Flavescentis, proportional quantity are in accordance with regulations pulverized, and go into interior decoction of pot of ceramic, and waste is left and taken medicinal liquid when boiling to finite concentration, and fluid temperature is kept about 45 ° of C; With Catechu, Galla Chinensis pulverization, fresh Herba Houttuyniae is smashed to pieces, adds in the medicinal liquid, stirs fully, becomes till the unguentum shape; Ointment is packed in the terrine, put into steamer, the closed container mouth steamed 3 hours; During with the ointment cold to 30 of the steaming ° C left and right sides, add Venenum Bufonis and Oleum menthae, fully stir, pack into then in the vial of sterilization, can use.

Embodiment 2

Processed with Rhizoma Zingiberis Recens Fructus Evodiae 20Kg, processed with salt Cortex Phellodendri 13Kg, Radix Sophorae Flavescentis 12Kg, fresh Herba Houttuyniae 18Kg, Catechu 15Kg, Galla Chinensis 10Kg, Venenum Bufonis powder 5Kg, Herba Menthae 7Kg.

Preparation method such as embodiment 1

Embodiment 3

Processed with Rhizoma Zingiberis Recens Fructus Evodiae 16Kg, processed with salt Cortex Phellodendri 16Kg, Radix Sophorae Flavescentis 15Kg, fresh Herba Houttuyniae 15Kg, Catechu 12Kg, Galla Chinensis 12Kg, Venenum Bufonis powder 5Kg, Herba Menthae 9Kg.

Preparation method such as embodiment 1

Experimental example: treating beri-beri clinical experiment data

This medicine is through many person-times clinical practice for many years, existingly imitates the hundreds of examples for the treatment of beriberi patient in various degree.No matter age size, sex difference, all obtain well-content effect.Be the relevant data of clinical treatment record below.

1, record is treated in 30 light beriberi patients' tracking.

12 years old-55 years old age, its middle school student 12 people, the male lives the rural area, and is with family in straitened circumstances, and living environment is poor, and father and mother all have beriberi.Other 18 people are adult, women 7 people, male 11 people, are engaged in raising, building, farmland work respectively.Living habit mostly is not to be liked foot bath, seldom changes footwear.Majority often wear water shoes, rubber overshoes, often noxious pollutants such as contact humidity, feces, water, soil.The most poverty of family bad habit such as pay no attention to hygiene.

Symptom is: toe seam is itched, hypodynia, skin are broken, skin is water-white, skin projection, is visible as the blister shape, gauffer is arranged.But firmly rub the scaling bits with the hands.

Treatment: with all healings in ointment, the every day of the coating embodiment of the invention 1 behind the 75% ethanol cleaning affected part 3 times, 3 days.When paying a return visit after 1 month, unmanned recurrence bounce-back.

2,50 serious beriberi patients are followed the tracks of the record for the treatment of.

Adult women 12 people wherein, 38 people are adult male, the age is 19 years old-50 years old, is engaged in raising, building, farmland work respectively.Custom is for seldom having a bath, seldom changing footwear, and most people have beriberi in the family, and majority often wear water shoes, rubber overshoes.Long-term contact water, soil, feces, humidity, pollutant etc.Some people does not have medication or treatment after suffering from beriberi.There are a few peoples to steep foot with salt and Borax, but poor effect, until being in a bad way.

Symptom is: fester in toe bifurcation place, and the water of suppurating, blood and slime with yellow pus, have stench flavor, and toe and half sole swelling have the slough phenomenon, the crust lividity, and pain is unbearably.It is difficult to walk, and has more than 10 people can not wear normal footwear, can only wear the simple and easy footwear that the front hollows out the back suspender belt, is in a bad way.

Treatment: the slough at patient's toe place is disposed, after disinfecting in alcohol, soaked full ointment (ointment that random packet adopts embodiment 1,2,3 to make) with the health cotton balls and smear the affected part, and press from both sides to the toe seam, swathe with gauze, change medicine every day 4 times to 5 times.Whenever change medicine one time, with the ethanol cleaning once.First-class medicine had better not be walked about, and rests 3 days, grows after the new organization normal activity again.Can fully recover in general 5-7 days, and pay a return visit after 1 month, it is invalid not have 1 people.Do not have 1 people and recur bounce-back.Warn simultaneously and keep foot's health.

Claims

1. external Chinese medicine for the treatment of beriberi, its active ingredient is made up of following crude drug and weight percentage thereof: processed with Rhizoma Zingiberis Recens Fructus Evodiae 10-20%, processed with salt Cortex Phellodendri 10-20%, Radix Sophorae Flavescentis 10-20%, fresh Herba Houttuyniae 8-18%, Catechu 8-15%, Galla Chinensis 8-15%, Venenum Bufonis powder 3-8%, Oleum menthae 5-12%.

2. the external Chinese medicine for the treatment of beriberi according to claim 1, wherein processed with Rhizoma Zingiberis Recens Fructus Evodiae 10-18%, processed with salt Cortex Phellodendri 13-20%, Radix Sophorae Flavescentis 12-20%, fresh Herba Houttuyniae 10-15%, Catechu 10-15%, Galla Chinensis 10-12%, Venenum Bufonis powder 5-7%, Oleum menthae 7-10%.

3. the external Chinese medicine for the treatment of beriberi according to claim 2, wherein processed with Rhizoma Zingiberis Recens Fructus Evodiae 16%, processed with salt Cortex Phellodendri 16%, Radix Sophorae Flavescentis 15%, fresh Herba Houttuyniae 15%, Catechu 12%, Galla Chinensis 12%, Venenum Bufonis powder 5%, Oleum menthae 9%.

4. according to the external Chinese medicine of the arbitrary described treatment beriberi of claim 1 to 3, its dosage form is unguentum.

5. the external preparation method of Chinese medicine of the described treatment beriberi of claim 4, comprise the steps: (1) weighting raw materials by weight, (2) produce the aqueous extract of processed with Rhizoma Zingiberis Recens Fructus Evodiae, processed with salt Cortex Phellodendri, Radix Sophorae Flavescentis, (3) water vapour steaming and decocting behind the mixing in the aqueous extract that Catechu and Galla Chinensis are pulverized, fresh Herba Houttuyniae is mashed adding (2) is become paste, (4) dry in the air cold to 25-30 ℃ of adding Venenum Bufonis powder and Oleum menthae, stirring gets final product.

6. preparation method according to claim 5, the crude drug in the described step (2) is crushed to powder.

7. preparation method according to claim 5, described step (3) digestion time is 3 hours.