CA2107789A1 - Inhibition retrovirale par des acides nucleiques antisens complementaires de sequences d'encapsidation - Google Patents
Inhibition retrovirale par des acides nucleiques antisens complementaires de sequences d'encapsidationInfo
- Publication number
- CA2107789A1 CA2107789A1 CA002107789A CA2107789A CA2107789A1 CA 2107789 A1 CA2107789 A1 CA 2107789A1 CA 002107789 A CA002107789 A CA 002107789A CA 2107789 A CA2107789 A CA 2107789A CA 2107789 A1 CA2107789 A1 CA 2107789A1
- Authority
- CA
- Canada
- Prior art keywords
- rna
- antisense
- dna
- packaging
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/027—New breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0337—Animal models for infectious diseases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68087391A | 1991-04-05 | 1991-04-05 | |
US680,873 | 1991-04-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2107789A1 true CA2107789A1 (fr) | 1992-10-06 |
Family
ID=24732881
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002107789A Abandoned CA2107789A1 (fr) | 1991-04-05 | 1992-04-03 | Inhibition retrovirale par des acides nucleiques antisens complementaires de sequences d'encapsidation |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0578776A4 (fr) |
JP (1) | JPH06506599A (fr) |
AU (1) | AU655279B2 (fr) |
CA (1) | CA2107789A1 (fr) |
WO (1) | WO1992017211A1 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4126484A1 (de) * | 1991-08-10 | 1993-02-11 | Bayer Ag | Expressionsvektoren und deren verwendung zur darstellung hiv-resistenter menschlicher zellen fuer therapeutische anwendungen |
DE4225094A1 (de) * | 1992-04-28 | 1993-11-04 | Frank Andreas Harald Meyer | Medikament zur gentherapeutischen behandlung von menschen, tieren und pflanzen, insbesondere zur blockierung der virenvermehrung und der tumorgene sowie verfahren zur herstellung des medikaments |
ES2312164T3 (es) | 1992-09-25 | 2009-02-16 | Aventis Pharma S.A. | Vectores de adenovirus para la transferencia de genes extraños en celulas del sistema nervioso central, particularmente en el cerebro. |
EP0598935A1 (fr) * | 1992-11-24 | 1994-06-01 | Bayer Ag | Vecteurs d'expression et leur utilisation pour la production de cellules humaines résistantes à HIV pour utilisation thérapeutique |
US5583035A (en) * | 1992-12-07 | 1996-12-10 | Bayer Aktiengesellschaft | HIV antisense expression vectors |
FR2702152B1 (fr) * | 1993-03-03 | 1995-05-24 | Inst Nat Sante Rech Med | Virus recombinants et leur utilisation en thérapie génique. |
US5712384A (en) * | 1994-01-05 | 1998-01-27 | Gene Shears Pty Ltd. | Ribozymes targeting retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs |
JP3691849B2 (ja) * | 1994-01-05 | 2005-09-07 | ジーン・シアーズ・ピーティーワイ・リミテッド | レトロウイルスパッケージング配列を標的とするリボザイム、その発現構築物、および斯かる構築物を含む組換えレトロウイルス |
KR100696410B1 (ko) * | 1994-01-05 | 2008-11-07 | 진 쉬어즈 피티와이., 엘티디. | 레트로바이러스 패키징 서열 발현 제작물을 표적으로 하는 리보자임 및 그러한 제작물을 가진 재조합 레트로바이러스 |
WO1995027783A1 (fr) * | 1994-04-06 | 1995-10-19 | Joshi Sukhwal Sadna | Inhibition de la multiplication du vih-1 dans des cellules de mammiferes |
US20020058636A1 (en) * | 1994-09-21 | 2002-05-16 | Geoffrey P. Symonds | Ribozymes targeting the retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs |
US7994144B2 (en) | 2001-07-10 | 2011-08-09 | Johnson & Johnson Research Pty, Limited | Process for the preparation of a composition of genetically modified hematopoietic progenitor cells |
NZ530624A (en) | 2001-07-10 | 2009-02-28 | Johnson & Johnson Res Pty Ltd | Compositions comprising C34+ hematopoietic progenitor cells transformed with an anti-viral agent for treating HIV |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4757055A (en) * | 1980-11-12 | 1988-07-12 | The Johns Hopkins University | Method for selectively controlling unwanted expression or function of foreign nucleic acids in animal or mammalian cells |
US4740463A (en) * | 1984-04-13 | 1988-04-26 | Massachusetts Institute Of Technology | Methods and artificial genes for antagonizing the function of an oncogene |
WO1988010311A1 (fr) * | 1987-06-26 | 1988-12-29 | Syntro Corporation | Cytomegalovirus humain recombinant contenant des genes etrangers et son utilisation |
ATE208813T1 (de) * | 1988-02-16 | 2001-11-15 | Greatbatch Gen Aid Ltd | Modifizierte zellen mit resistenz gegen retroviralinfektionen |
EP0402402B1 (fr) * | 1988-02-26 | 1995-12-27 | Worcester Foundation For Biomedical Research, Inc. | Inhibition du htlv-iii par des oligonucleotides exogenes |
-
1992
- 1992-04-03 AU AU17780/92A patent/AU655279B2/en not_active Ceased
- 1992-04-03 EP EP92910993A patent/EP0578776A4/fr not_active Withdrawn
- 1992-04-03 CA CA002107789A patent/CA2107789A1/fr not_active Abandoned
- 1992-04-03 WO PCT/US1992/002911 patent/WO1992017211A1/fr not_active Application Discontinuation
- 1992-04-03 JP JP4510048A patent/JPH06506599A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JPH06506599A (ja) | 1994-07-28 |
WO1992017211A1 (fr) | 1992-10-15 |
AU1778092A (en) | 1992-11-02 |
EP0578776A1 (fr) | 1994-01-19 |
AU655279B2 (en) | 1994-12-15 |
EP0578776A4 (fr) | 1995-04-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued | ||
FZDE | Discontinued |
Effective date: 20010403 |